Clinical outcomes after ablation and pacing therapy for atrial fibrillation : a meta-analysis.

Abstract:

BACKGROUND:Radiofrequency ablation of the atrioventricular node and permanent pacing are used for symptomatic relief in patients with medically refractory atrial fibrillation. In this study, meta-analysis was used to clarify clinical outcomes and survival after ablation and pacing therapy using data from the published literature. METHODS AND RESULTS:We used 21 studies with a total of 1181 patients in the meta-analysis. All patients had medically refractory atrial tachyarrhythmias, primarily atrial fibrillation (97%). Nineteen measures of clinical outcome, encompassing quality of life, ventricular function, exercise duration, and healthcare use, were derived from the studies. The meta-analysis demonstrated significant improvement after ablation and pacing therapy in all outcome measures except fractional shortening, which demonstrated a trend toward improvement (P=0.08). Ejection fraction did show significant improvement (P<0.001). The calculated 1-year total and sudden death mortality rates after ablation and pacing therapy were 6.3% and 2.0%, respectively. CONCLUSIONS:Ablation and pacing therapy improves a broad range of clinical outcomes for patients with medically refractory atrial fibrillation. The calculated 1-year mortality rates after this therapy are low and comparable with medical therapy.

journal_name

Circulation

journal_title

Circulation

authors

Wood MA,Brown-Mahoney C,Kay GN,Ellenbogen KA

doi

10.1161/01.cir.101.10.1138

subject

Has Abstract

pub_date

2000-03-14 00:00:00

pages

1138-44

issue

10

eissn

0009-7322

issn

1524-4539

journal_volume

101

pub_type

杂志文章,meta分析
  • Beta2-adrenergic receptor polymorphisms and risk of incident cardiovascular events in the elderly.

    abstract:BACKGROUND:Genetic polymorphisms at codons 16 and 27 of the beta2-adrenergic receptor have been associated with altered response to sympathetic stimulation. We examined these polymorphisms in relation to cardiovascular event risk in the Cardiovascular Health Study. METHODS AND RESULTS:A total of 808 black and 4441 whi...

    journal_title:Circulation

    pub_type: 杂志文章

    doi:10.1161/01.CIR.0000065231.07729.92

    authors: Heckbert SR,Hindorff LA,Edwards KL,Psaty BM,Lumley T,Siscovick DS,Tang Z,Durda JP,Kronmal RA,Tracy RP

    更新日期:2003-04-22 00:00:00

  • Regional three-dimensional geometry and function of left ventricles with fibrous aneurysms. A cine-computed tomography study.

    abstract:BACKGROUND:To assess the extent and nature of the dysfunction surrounding aneurysms of the left ventricle (LV), we examined the parameters of local and global three-dimensional shape, size, and function of LVs of eight patients with histologically confirmed anterior fibrous aneurysms. METHODS AND RESULTS:Three-dimensi...

    journal_title:Circulation

    pub_type: 杂志文章

    doi:10.1161/01.cir.84.3.1072

    authors: Lessick J,Sideman S,Azhari H,Marcus M,Grenadier E,Beyar R

    更新日期:1991-09-01 00:00:00

  • Decreased myocyte tension development and calcium responsiveness in rat right ventricular pressure overload.

    abstract:BACKGROUND:The contractile dysfunction observed in end-stage myocardial hypertrophy has at its base an abnormality in myocyte function. However, whether depressed contractile function is related to an alteration in contractile protein function is presently unknown. METHODS AND RESULTS:Contractile force, tension, and c...

    journal_title:Circulation

    pub_type: 杂志文章

    doi:10.1161/01.cir.95.9.2312

    authors: Fan D,Wannenburg T,de Tombe PP

    更新日期:1997-05-06 00:00:00

  • Left ventricular function during intra-aortic balloon pumping assessed by multigated cardiac blood pool imaging.

    abstract::The effectiveness of intra-aortic balloon pumping in augmenting ventricular performance during acute myocardial ischemic syndromes was determined by noninvasive multigated cardiac blood pool imaging. Nine patients with unstable angina refractory to medical therapy and nine patients with acute myocardial infarction com...

    journal_title:Circulation

    pub_type: 杂志文章

    doi:

    authors: Nichols AB,Pohost GM,Gold HK,Leinbach RC,Beller GA,McKusick KA,Strauss HW,Buckley MJ

    更新日期:1978-09-01 00:00:00

  • Inherited arrhythmias: a National Heart, Lung, and Blood Institute and Office of Rare Diseases workshop consensus report about the diagnosis, phenotyping, molecular mechanisms, and therapeutic approaches for primary cardiomyopathies of gene mutations affe

    abstract::The National Heart, Lung, and Blood Institute and Office of Rare Diseases at the National Institutes of Health organized a workshop (September 14 to 15, 2006, in Bethesda, Md) to advise on new research directions needed for improved identification and treatment of rare inherited arrhythmias. These included the followi...

    journal_title:Circulation

    pub_type: 杂志文章

    doi:10.1161/CIRCULATIONAHA.107.711689

    authors: Lehnart SE,Ackerman MJ,Benson DW Jr,Brugada R,Clancy CE,Donahue JK,George AL Jr,Grant AO,Groft SC,January CT,Lathrop DA,Lederer WJ,Makielski JC,Mohler PJ,Moss A,Nerbonne JM,Olson TM,Przywara DA,Towbin JA,Wang LH,M

    更新日期:2007-11-13 00:00:00

  • Prioritizing Functional Capacity as a Principal End Point for Therapies Oriented to Older Adults With Cardiovascular Disease: A Scientific Statement for Healthcare Professionals From the American Heart Association.

    abstract::Adults are living longer, and cardiovascular disease is endemic in the growing population of older adults who are surviving into old age. Functional capacity is a key metric in this population, both for the perspective it provides on aggregate health and as a vital goal of care. Whereas cardiorespiratory function has ...

    journal_title:Circulation

    pub_type: 杂志文章,评审

    doi:10.1161/CIR.0000000000000483

    authors: Forman DE,Arena R,Boxer R,Dolansky MA,Eng JJ,Fleg JL,Haykowsky M,Jahangir A,Kaminsky LA,Kitzman DW,Lewis EF,Myers J,Reeves GR,Shen WK,American Heart Association Council on Clinical Cardiology; Council on Cardiovascular and St

    更新日期:2017-04-18 00:00:00

  • Right ventricular/arterial coupling in the patient with left ventricular assistance.

    abstract:BACKGROUND:Improvements are known to occur in right ventricular (RV) ejection fraction after the use of a left ventricular assist device (LVAD); less is known, however, about the mechanism of this improvement. The concept of ventricular/arterial coupling was applied to investigate whether systolic pump function or afte...

    journal_title:Circulation

    pub_type: 杂志文章

    doi:

    authors: Morita S,Kormos RL,Mandarino WA,Eishi K,Kawai A,Gasior TA,Deneault LG,Armitage JM,Hardesty RL,Griffith BP

    更新日期:1992-11-01 00:00:00

  • Site-dependent intra-atrial conduction delay. Relationship to initiation of atrial fibrillation.

    abstract:BACKGROUND:Atrial dysrhythmia patients have exaggerated intra-atrial conduction delays and prolonged relative refractoriness in response to atrial premature depolarizations (APDs). Furthermore, atrial fibrillation (AF) is more readily inducible by APDs from the high right atrium (HRA) than the coronary sinus (CS). In t...

    journal_title:Circulation

    pub_type: 杂志文章

    doi:10.1161/01.cir.94.3.384

    authors: Papageorgiou P,Monahan K,Boyle NG,Seifert MJ,Beswick P,Zebede J,Epstein LM,Josephson ME

    更新日期:1996-08-01 00:00:00

  • Ninety-minute exclusion of acute myocardial infarction by use of quantitative point-of-care testing of myoglobin and troponin I.

    abstract:BACKGROUND:Diagnostic strategies with ECG and serum cardiac markers have been used to rule out acute myocardial infarction in 6 to 12 hours. The present study evaluated whether a multimarker strategy that used point-of-care measurement of myoglobin, creatine kinase (CK)-MB, and troponin I could exclude acute myocardial...

    journal_title:Circulation

    pub_type: 杂志文章

    doi:10.1161/hc3801.096336

    authors: McCord J,Nowak RM,McCullough PA,Foreback C,Borzak S,Tokarski G,Tomlanovich MC,Jacobsen G,Weaver WD

    更新日期:2001-09-25 00:00:00

  • Autologous endothelialized vein allograft: a solution in the search for small-caliber grafts in coronary artery bypass graft operations.

    abstract:BACKGROUND:Early graft failure after the use of less satisfactory autologous grafts (30% of all vein grafts) is caused primarily by the following problems: (1) suitable autologous transplants are limited; (2) biotechnology has not yet been able to produce reliable graft substitutes that are legally and ethically approv...

    journal_title:Circulation

    pub_type: 临床试验,杂志文章

    doi:

    authors: Lamm P,Juchem G,Milz S,Schuffenhauer M,Reichart B

    更新日期:2001-09-18 00:00:00

  • Dobutamine echocardiography and quantitative rest-redistribution 201Tl tomography in myocardial hibernation. Relation of contractile reserve to 201Tl uptake and comparative prediction of recovery of function.

    abstract:BACKGROUND:The purposes of this study were to evaluate the comparative accuracy of dobutamine echocardiography and quantitative rest-redistribution 201Tl tomography in the prediction of recovery of function after revascularization and to assess the relation of contractile reserve to thallium uptake. METHODS AND RESULT...

    journal_title:Circulation

    pub_type: 杂志文章

    doi:10.1161/01.cir.95.3.626

    authors: Qureshi U,Nagueh SF,Afridi I,Vaduganathan P,Blaustein A,Verani MS,Winters WL Jr,Zoghbi WA

    更新日期:1997-02-04 00:00:00

  • Reduction of stroke events with pravastatin: the Prospective Pravastatin Pooling (PPP) Project.

    abstract:BACKGROUND:Stroke is a leading cause of death and disability. Although clinical trials of the early lipid-lowering therapies did not demonstrate a reduction in the rates of stroke, data from recently completed statin trials strongly suggest benefit. METHODS AND RESULTS:The effect of pravastatin 40 mg/d on stroke event...

    journal_title:Circulation

    pub_type: 临床试验,杂志文章,meta分析,随机对照试验

    doi:10.1161/01.cir.103.3.387

    authors: Byington RP,Davis BR,Plehn JF,White HD,Baker J,Cobbe SM,Shepherd J

    更新日期:2001-01-23 00:00:00

  • Understanding the coronary heart disease versus total cardiovascular mortality paradox: a method to enhance the comparability of cardiovascular death statistics in the United States.

    abstract:BACKGROUND:Coronary heart disease (CHD) represents the largest share of cardiovascular disease in the United States, but there are conspicuous discrepancies between CHD and total cardiovascular death rates across the states, possibly due in part to variations in physician assignment of causes of death. Our aim was to i...

    journal_title:Circulation

    pub_type: 杂志文章

    doi:10.1161/CIRCULATIONAHA.105.595777

    authors: Murray CJ,Kulkarni SC,Ezzati M

    更新日期:2006-05-02 00:00:00

  • Endothelin-converting enzyme expression in the rat vascular injury model and human coronary atherosclerosis.

    abstract:BACKGROUND:Endothelin 1 has been implicated in various human diseases, including atherosclerosis. In this study, we examined the expression and localization of endothelin-converting enzyme-1 (ECE-1), the final key enzyme of endothelin 1 processing, in rat carotid arteries after balloon injury and in human coronary athe...

    journal_title:Circulation

    pub_type: 杂志文章

    doi:10.1161/01.cir.95.1.221

    authors: Minamino T,Kurihara H,Takahashi M,Shimada K,Maemura K,Oda H,Ishikawa T,Uchiyama T,Tanzawa K,Yazaki Y

    更新日期:1997-01-07 00:00:00

  • N-methyl-1-deoxynojirimycin (MOR-14), an alpha-glucosidase inhibitor, markedly reduced infarct size in rabbit hearts.

    abstract:BACKGROUND:N-methyl-1-deoxynojirimycin (MOR-14), an alpha-glucosidase inhibitor, reduces the glycogenolytic rate by inhibiting the alpha-1,6-glucosidase of glycogen-debranching enzyme in the liver, in addition to possessing an antihyperglycemic action by blocking alpha-1,4-glucosidase in the intestine. Because the redu...

    journal_title:Circulation

    pub_type: 杂志文章

    doi:10.1161/01.cir.97.13.1290

    authors: Arai M,Minatoguchi S,Takemura G,Uno Y,Kariya T,Takatsu H,Fujiwara T,Higashioka M,Yoshikuni Y,Fujiwara H

    更新日期:1998-04-07 00:00:00

  • Functional right-heart replacement with skeletal muscle ventricles.

    abstract::Skeletal muscle ventricles were constructed from the latissimus dorsi in seven dogs. All skeletal muscle ventricles underwent a vascular delay period followed by 4-7 weeks of electrical preconditioning. In group 1 (n = 5), the skeletal muscle ventricle was used to replace native right-heart function. Venous return fro...

    journal_title:Circulation

    pub_type: 杂志文章

    doi:

    authors: Bridges CR Jr,Hammond RL,Dimeo F,Anderson WA,Stephenson LW

    更新日期:1989-11-01 00:00:00

  • Lack of Ability to Present Antigens on Major Histocompatibility Complex Class II Molecules Aggravates Atherosclerosis in ApoE-/- Mice.

    abstract:BACKGROUND:Hypercholesterolemic mice lacking factors required for activation of CD4+ T cells are characterized by reduced development of atherosclerosis. Consequently, it has been assumed that atherosclerosis involves loss of tolerance against modified self-antigens generated in response to hypercholesterolemia and tha...

    journal_title:Circulation

    pub_type: 杂志文章

    doi:10.1161/CIRCULATIONAHA.118.039288

    authors: Wigren M,Rattik S,Yao Mattisson I,Tomas L,Grönberg C,Söderberg I,Alm R,Sundius L,Ljungcrantz I,Björkbacka H,Fredrikson GN,Nilsson J

    更新日期:2019-05-28 00:00:00

  • Ghrelin inhibits proinflammatory responses and nuclear factor-kappaB activation in human endothelial cells.

    abstract:BACKGROUND:Ghrelin is a novel growth hormone-releasing peptide that has been shown to improve cachexia in heart failure and cancer and to ameliorate the hemodynamic and metabolic disturbances in septic shock. Because cytokine-induced inflammation is critical in these pathological states and because the growth hormone s...

    journal_title:Circulation

    pub_type: 杂志文章

    doi:10.1161/01.CIR.0000127956.43874.F2

    authors: Li WG,Gavrila D,Liu X,Wang L,Gunnlaugsson S,Stoll LL,McCormick ML,Sigmund CD,Tang C,Weintraub NL

    更新日期:2004-05-11 00:00:00

  • Prognostic value of lead V1 ST elevation during acute inferior myocardial infarction.

    abstract:BACKGROUND:Lead V(1) directly faces the right ventricle and may exhibit ST elevation during an acute inferior myocardial infarction when the right ventricle is also involved. Leads V(1) and V(3) indirectly face the posterolateral left ventricle, and ST depression ("mirror-image" ST elevation) in V(1) through V(3) may r...

    journal_title:Circulation

    pub_type: 杂志文章,随机对照试验

    doi:10.1161/CIRCULATIONAHA.109.924068

    authors: Wong CK,Gao W,Stewart RA,French JK,Aylward PE,Benatar J,White HD,Hirulog and Early Reperfusion or Occlusion-2 Investigators.

    更新日期:2010-08-03 00:00:00

  • Recurrence of ventricular fibrillation in acute ischemic heart disease.

    abstract::We assessed factors during an initial episode of ventricular fibrillation that may be predictive of recurrence. Of 141 consecutive patients with acute ischemic heart disease who survived an initial episode of ventricular fibrillation, 41 (29%) had recurrent ventricular fibrillation during hospitalization. The incidenc...

    journal_title:Circulation

    pub_type: 杂志文章

    doi:10.1161/01.cir.64.6.1163

    authors: Logan KR,McIlwaine WJ,Adgey AA,Pantridge JF

    更新日期:1981-12-01 00:00:00

  • Short-term effect of atrial fibrillation on atrial contractile function in humans.

    abstract:BACKGROUND:Conversion of chronic atrial fibrillation (AF) is associated with atrial stunning, but the short-term effect of a brief episode of AF on left atrial appendage (LAA) emptying velocity is unknown. The purpose of this study was to determine whether a short episode of AF affects left atrial function and whether ...

    journal_title:Circulation

    pub_type: 杂志文章

    doi:10.1161/01.cir.99.23.3024

    authors: Daoud EG,Marcovitz P,Knight BP,Goyal R,Man KC,Strickberger SA,Armstrong WF,Morady F

    更新日期:1999-06-15 00:00:00

  • Prediction of successful ablation site of concealed posteroseptal accessory pathways by a novel algorithm using baseline electrophysiological parameters: implication for an abbreviated ablation procedure.

    abstract:BACKGROUND:Radiofrequency catheter ablation of concealed posteroseptal accessory pathways (APS) has been a relatively difficult task for electrophysiologists. Without a detailed mapping procedure, the left versus the right posteroseptal AP could not be distinguished. We investigated the electrophysiological characteris...

    journal_title:Circulation

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1161/01.cir.93.5.982

    authors: Chiang CE,Chen SA,Tai CT,Wu TJ,Lee SH,Cheng CC,Chiou CW,Ueng KC,Wen ZC,Chang MS

    更新日期:1996-03-01 00:00:00

  • Ibutilide, a methanesulfonanilide antiarrhythmic, is a potent blocker of the rapidly activating delayed rectifier K+ current (IKr) in AT-1 cells. Concentration-, time-, voltage-, and use-dependent effects.

    abstract:BACKGROUND:Ibutilide is an action potential-prolonging antiarrhythmic currently in clinical trials. The drug shares structural similarities with E-4031 and dofetilide, specific blockers of the rapidly activating delayed rectifier K+ current (IKr). However, previous in vitro studies in guinea pig myocytes have indicated...

    journal_title:Circulation

    pub_type: 杂志文章

    doi:10.1161/01.cir.91.6.1799

    authors: Yang T,Snyders DJ,Roden DM

    更新日期:1995-03-15 00:00:00

  • Impact of controlled pericardial drainage on critical cardiac tamponade with acute type A aortic dissection.

    abstract:BACKGROUND:Cardiac tamponade is associated with fatal outcomes for patients with acute type A aortic dissection, and the presence of cardiac tamponade should prompt urgent aortic repair. However, treatment of the patient with critical cardiac tamponade who cannot survive until surgery remains unclear. We analyzed our e...

    journal_title:Circulation

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1161/CIRCULATIONAHA.111.082685

    authors: Hayashi T,Tsukube T,Yamashita T,Haraguchi T,Matsukawa R,Kozawa S,Ogawa K,Okita Y

    更新日期:2012-09-11 00:00:00

  • Regulation of shear stress in the canine coronary microcirculation.

    abstract:BACKGROUND:Physical forces, such as pressure and flow, are well known to affect vascular function in the coronary circulation. Increases in shear stress produce vasodilation in coronary arterioles in vitro, and constant-flow preparations suggest a role for shear stress-induced vasodilation during adjustments to metabol...

    journal_title:Circulation

    pub_type: 杂志文章

    doi:10.1161/01.cir.100.14.1555

    authors: Stepp DW,Nishikawa Y,Chilian WM

    更新日期:1999-10-05 00:00:00

  • Acute rheumatic fever and rheumatic heart disease: incidence and progression in the Northern Territory of Australia, 1997 to 2010.

    abstract:BACKGROUND:Although acute rheumatic fever (ARF) and its sequel, rheumatic heart disease (RHD), continue to cause a large burden of morbidity and mortality in disadvantaged populations, most studies investigating the effectiveness of control programs date from the 1950s. A control program, including a disease register, ...

    journal_title:Circulation

    pub_type: 杂志文章

    doi:10.1161/CIRCULATIONAHA.113.001477

    authors: Lawrence JG,Carapetis JR,Griffiths K,Edwards K,Condon JR

    更新日期:2013-07-30 00:00:00

  • Left ventricular concentric remodeling rather than left ventricular hypertrophy is related to the insulin resistance syndrome in elderly men.

    abstract:BACKGROUND:Associations between left ventricular (LV) geometry and the insulin resistance syndrome have been found, mostly in small studies of middle-aged hypertensives. The purpose of this study was to elucidate these associations through the use of a large sample of elderly men. METHODS AND RESULTS:We investigated 4...

    journal_title:Circulation

    pub_type: 杂志文章

    doi:10.1161/01.cir.101.22.2595

    authors: Sundström J,Lind L,Nyström N,Zethelius B,Andrén B,Hales CN,Lithell HO

    更新日期:2000-06-06 00:00:00

  • Lipoprotein(a), PCSK9 Inhibition, and Cardiovascular Risk.

    abstract:BACKGROUND:Lipoprotein(a) [Lp(a)] may play a causal role in atherosclerosis. PCSK9 (proprotein convertase subtilisin/kexin 9) inhibitors have been shown to significantly reduce plasma Lp(a) concentration. However, the relationship between Lp(a) levels, PCSK9 inhibition, and cardiovascular risk reduction remains undefin...

    journal_title:Circulation

    pub_type: 杂志文章,随机对照试验

    doi:10.1161/CIRCULATIONAHA.118.037184

    authors: O'Donoghue ML,Fazio S,Giugliano RP,Stroes ESG,Kanevsky E,Gouni-Berthold I,Im K,Lira Pineda A,Wasserman SM,Češka R,Ezhov MV,Jukema JW,Jensen HK,Tokgözoğlu SL,Mach F,Huber K,Sever PS,Keech AC,Pedersen TR,Sabatine MS

    更新日期:2019-03-19 00:00:00

  • Mechanisms by which adenosine restores conduction in dormant canine pulmonary veins.

    abstract:BACKGROUND:Adenosine acutely reconnects pulmonary veins (PVs) after radiofrequency application, revealing "dormant conduction" and identifying PVs at risk of reconnection, but the underlying mechanisms are unknown. METHODS AND RESULTS:Canine PV and left-atrial (LA) action potentials were recorded with standard microel...

    journal_title:Circulation

    pub_type: 杂志文章

    doi:10.1161/CIRCULATIONAHA.109.893107

    authors: Datino T,Macle L,Qi XY,Maguy A,Comtois P,Chartier D,Guerra PG,Arenal A,Fernández-Avilés F,Nattel S

    更新日期:2010-03-02 00:00:00

  • Evaluation of combined valvular prolapse syndrome by two-dimensional echocardiography.

    abstract::The patterns of aortic and tricuspid valve motion in 50 patients with mitral valve prolapse were analyzed by wide-angle, phased-array, two-dimensional echocardiography. Twelve patients (24%) had redundant aortic leaflets bulging into the left ventricular outflow tract during diastole. Eight of 12 patients had aortic r...

    journal_title:Circulation

    pub_type: 杂志文章

    doi:10.1161/01.cir.65.1.174

    authors: Ogawa S,Hayashi J,Sasaki H,Tani M,Akaishi M,Mitamura H,Sano M,Hoshino T,Handa S,Nakamura Y

    更新日期:1982-01-01 00:00:00