Recurrence of ventricular fibrillation in acute ischemic heart disease.

abstract：:For the past 5 years, investigators from many different laboratories have contributed to a greatly increased understanding of two very important lipid-carrying proteins in plasma--apo B-100 and apo B-48. Apo B-100, an extremely large protein composed of 4,536 amino acids, is synthesized by the liver and is crucial for...

journal_title：Circulation

authors： Young SG

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND:Age-adjusted stroke incidence has decreased over the past 50 years, likely as a result of changes in the prevalence and impact of various stroke risk factors. An updated version of the Framingham Stroke Risk Profile (FSRP) might better predict current risks in the FHS (Framingham Heart Study) and other cohor...

journal_title：Circulation

authors： Dufouil C,Beiser A,McLure LA,Wolf PA,Tzourio C,Howard VJ,Westwood AJ,Himali JJ,Sullivan L,Aparicio HJ,Kelly-Hayes M,Ritchie K,Kase CS,Pikula A,Romero JR,D'Agostino RB,Samieri C,Vasan RS,Chêne G,Howard G,Seshadri S

更新日期：2017-03-21 00:00:00

abstract：BACKGROUND:The pulmonary autograft procedure (Ross) is now considered the gold standard for aortic valve replacement. One of its advantages is the freedom from macroemboli without anticoagulation. Whether this holds true for circulating microemboli, detectable as high-intensity transient Doppler signals (HITS), has not...

journal_title：Circulation

authors： Nötzold A,Droste DW,Hagedorn G,Berndt S,Kaps M,Graf B,Sievers HH

更新日期：1997-09-16 00:00:00

abstract：:D8/17, a B cell alloantigen, and its occurrence with DR/DQ antigens was examined in 54 patients with rheumatic heart disease and matched North Indian controls. Thirty-four patients (62.9%) carried D8/17 as compared with a frequency of 12.5% in controls (chi 2 by Yates', 18.75; p less than 0.0001). A marginally increas...

journal_title：Circulation

authors： Taneja V,Mehra NK,Reddy KS,Narula J,Tandon R,Vaidya MC,Bhatia ML

更新日期：1989-08-01 00:00:00

abstract：BACKGROUND:Since Mexican Americans have adverse patterns of risk factors for myocardial infarction relative to non-Hispanic whites, the incidence of myocardial infarction should be greater among Mexican Americans than among non-Hispanic whites. This expectation conflicts with reports generated from death certificate re...

journal_title：Circulation

authors： Goff DC,Nichaman MZ,Chan W,Ramsey DJ,Labarthe DR,Ortiz C

更新日期：1997-03-18 00:00:00

abstract：BACKGROUND:Apoptosis in human atherosclerotic coronary plaques possibly causes plaque destabilization by contributing to the weakening and breaking down of the fibrous cap. We tested the hypothesis that apoptosis is quantitatively increased in unstable atherosclerotic plaques. METHODS AND RESULTS:We analyzed the expre...

journal_title：Circulation

authors： Rossi ML,Marziliano N,Merlini PA,Bramucci E,Canosi U,Belli G,Parenti DZ,Mannucci PM,Ardissino D

更新日期：2004-09-28 00:00:00

abstract：BACKGROUND:Atrial fibrillation (AF), the most common sustained arrhythmia in hypertrophic cardiomyopathy (HCM), is capable of producing symptoms that impact quality of life and is associated with risk for embolic stroke. However, the influence of AF on clinical course and outcome in HCM remains incompletely resolved. ...

journal_title：Circulation

authors： Rowin EJ,Hausvater A,Link MS,Abt P,Gionfriddo W,Wang W,Rastegar H,Estes NAM,Maron MS,Maron BJ

更新日期：2017-12-19 00:00:00

abstract：BACKGROUND:Low-density lipoprotein (LDL) impairs endothelial cell function by uncoupling endothelial nitric oxide synthase (eNOS) activity, which allows superoxide anion (O2*-)) to be generated rather than nitric oxide (*NO). Recent reports indicate that apolipoprotein (apo) A-1 mimetics inhibit the development of athe...

journal_title：Circulation

authors： Ou Z,Ou J,Ackerman AW,Oldham KT,Pritchard KA Jr

更新日期：2003-03-25 00:00:00

abstract：BACKGROUND:Incomplete ST-segment resolution (STR) after successful primary angioplasty for acute myocardial infarction (AMI) is associated with a poor prognosis. We used intracoronary Doppler velocimetry to investigate whether incomplete STR after primary angioplasty is a marker of severe microcirculatory dysfunction. ...

journal_title：Circulation

authors： Feldman LJ,Coste P,Furber A,Dupouy P,Slama MS,Monassier JP,Tron C,Lafont A,Faraggi M,Le Guludec D,Dubois-Randé JL,Steg PG,FRench Optimal STenting-2 Invest.

更新日期：2003-06-03 00:00:00

abstract：:Sustained-release diltiazem (D-SR) and sustained-release verapamil (V-SR) when given twice a day have been successfully used to treat both essential hypertension and angina pectoris. Review of available studies indicates that 120 to 180 mg D-SR twice a day and 240 mg V-SR once or twice a day can lower diastolic pressu...

journal_title：Circulation

authors： Klein MD,Weiner DA

更新日期：1987-06-01 00:00:00

abstract：BACKGROUND:In the experimental setting, it has been demonstrated that preconditioning myocardium before prolonged occlusion with brief ischemic episodes affords substantial protection to the cells by delaying lethal injury, thereby limiting infarct size. Whether the same occurs in humans remains unknown. METHODS AND R...

journal_title：Circulation

authors： Ottani F,Galvani M,Ferrini D,Sorbello F,Limonetti P,Pantoli D,Rusticali F

更新日期：1995-01-15 00:00:00

abstract：BACKGROUND:Angiogenesis is a promising treatment strategy for patients who are not candidates for standard revascularization, because it promotes the growth of new blood vessels in ischemic myocardium. METHODS AND RESULTS:We conducted a randomized, double-blind, placebo-controlled study of basic fibroblast growth fact...

journal_title：Circulation

authors： Laham RJ,Sellke FW,Edelman ER,Pearlman JD,Ware JA,Brown DL,Gold JP,Simons M

更新日期：1999-11-02 00:00:00

abstract：BACKGROUND:Mitral regurgitation (MR) due to mitral valve prolapse (MVP) is often treatable by surgical repair. However, the very long-term (>10-year) durability of repair in both anterior leaflet prolapse (AL-MVP) and posterior leaflet prolapse (PL-MVP) is unknown. METHODS AND RESULTS:In 917 patients (aged 65+/-13 yea...

journal_title：Circulation

authors： Mohty D,Orszulak TA,Schaff HV,Avierinos JF,Tajik JA,Enriquez-Sarano M

更新日期：2001-09-18 00:00:00

abstract：BACKGROUND:The age association of cardiovascular disease may be in part because its metabolic risk factors tend to rise with age. Few studies have analyzed age associations of multiple metabolic risks in the same population, especially in nationally representative samples. We examined worldwide variations in the age as...

journal_title：Circulation

authors： Singh GM,Danaei G,Pelizzari PM,Lin JK,Cowan MJ,Stevens GA,Farzadfar F,Khang YH,Lu Y,Riley LM,Lim SS,Ezzati M

更新日期：2012-05-08 00:00:00

abstract：BACKGROUND:Low endothelial shear stress (ESS) promotes the development of atherosclerosis; however, its role in the progression of atherosclerotic plaques and evolution to inflamed high-risk plaques has not been studied. Our hypothesis was that the lowest values of ESS are responsible for the development of high-risk c...

journal_title：Circulation

authors： Chatzizisis YS,Jonas M,Coskun AU,Beigel R,Stone BV,Maynard C,Gerrity RG,Daley W,Rogers C,Edelman ER,Feldman CL,Stone PH

更新日期：2008-02-26 00:00:00

abstract：:Hypertrophic cardiomyopathy (HCM) or idiopathic hypertrophic subaortic stenosis (IHSS) has been defined as an autosomal dominant myocardial disease characterized by specific physical findings, echocardiographic features, asymmetric septal hypertrophy and disordered myocardial architecture. Echocardiographic and scinti...

journal_title：Circulation

authors： Come PC,Bulkley BH,Goodman ZD,Hutchins GM,Pitt B,Fortuin NJ

更新日期：1977-06-01 00:00:00

abstract：:Global ventricular function was evaluated by both multiple gated cardiac blood pool scans (MUGA) and contrast ventriculograms in a group of 17 patients with suspected coronary artery disease. The contrast ventriculograms were analyzed frame by frame to generate a volume versus time curve for each patient, while the tr...

journal_title：Circulation

authors： Burow RD,Strauss HW,Singleton R,Pond M,Rehn T,Bailey IK,Griffith LC,Nickoloff E,Pitt B

更新日期：1977-12-01 00:00:00

abstract：BACKGROUND:There has been increasing interest in the development of agents that utilize endogenous adenosine to exert their actions. We tested the hypothesis that substances that either potentiate the activity (allosteric enhancers) or increase the interstitial concentration (inhibitors of metabolism) of endogenous ade...

journal_title：Circulation

authors： Dennis DM,Raatikainen MJ,Martens JR,Belardinelli L

更新日期：1996-11-15 00:00:00

abstract：BACKGROUND:The development of selective atrial antiarrhythmic agents is a current strategy for suppression of atrial fibrillation (AF). METHODS AND RESULTS:Whole-cell patch clamp techniques were used to evaluate inactivation of peak sodium channel current (I(Na)) in myocytes isolated from canine atria and ventricles. ...

journal_title：Circulation

authors： Burashnikov A,Di Diego JM,Zygmunt AC,Belardinelli L,Antzelevitch C

更新日期：2007-09-25 00:00:00

abstract：BACKGROUND:Short-term hibernating myocardium is characterized by a decrease in contractile function in proportion to the reduced myocardial blood flow. Myocardial creatine phosphate content, initially decreased during the first minutes of ischemia, returns to near-control values, the ischemia-induced net lactate produc...

journal_title：Circulation

authors： Schulz R,Rose J,Martin C,Brodde OE,Heusch G

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:Randomized clinical trials have shown that multivessel coronary angioplasty is feasible and provides similar long-term survival as bypass surgery in selected patients. However, the higher need for repeat intervention, in particular, coronary artery bypass graft surgery, remains a problem. The objective of th...

journal_title：Circulation

authors： Moussa I,Reimers B,Moses J,Di Mario C,Di Francesco L,Ferraro M,Colombo A

更新日期：1997-12-02 00:00:00

abstract：BACKGROUND:In recent decades, the rates of incident acute myocardial infarction (AMI) have declined in the United States, yet disparities by sex remain. In an integrated healthcare delivery system, we examined temporal trends in incident AMI among women and men. METHODS:We identified hospitalized AMI among members ≥35...

journal_title：Circulation

authors： Mefford MT,Li BH,Qian L,Reading SR,Harrison TN,Scott RD,Cavendish JJ,Jacobsen SJ,Kanter MH,Woodward M,Reynolds K

更新日期：2020-02-18 00:00:00

abstract：:To assess the effects of moderate potassium cardioplegia (37 mEq/l KCl) on the severity of myocardial ischemia during arrest and on post arrest ventricular function, 32 isolated, isovolumic feline hearts were studied before, during and 1 hour after ischemic arrest. Normothermia (37 degrees C) was maintained in the rem...

journal_title：Circulation

authors： Schaff HV,Dombroff R,Flaherty JT,Bulkley BH,Hutchins GM,Goldman RA,Gott VL

更新日期：1978-08-01 00:00:00

abstract：BACKGROUND:Vascular injury and atherothrombosis involve vessel infiltration by inflammatory leukocytes, migration of medial vascular smooth muscle cells to the intimal layer, and ultimately acute thrombosis. A strategy to simultaneously target these pathological processes has yet to be identified. The secreted protein,...

journal_title：Circulation

authors： Patel S,Huang YW,Reheman A,Pluthero FG,Chaturvedi S,Mukovozov IM,Tole S,Liu GY,Li L,Durocher Y,Ni H,Kahr WH,Robinson LA

更新日期：2012-09-11 00:00:00

abstract：BACKGROUND:Sympathetic activation and respiratory abnormalities may each be implicated in the pathophysiology of congestive heart failure (CHF). Chemoreflexes are an important mechanism regulating both sympathetic drive and breathing. We therefore tested the hypothesis that chemoreflex function is altered in CHF. METH...

journal_title：Circulation

authors： Narkiewicz K,Pesek CA,van de Borne PJ,Kato M,Somers VK

更新日期：1999-07-20 00:00:00

abstract：BACKGROUND:Postmortem interrogations of cardiac implantable electronic devices (CIEDs), recommended at autopsy in suspected cases of sudden cardiac death, are rarely performed, and data on systematic postmortem CIED analysis in the forensic pathology are missing. The aim of the study was to determine whether nonselecti...

journal_title：Circulation

authors： Lacour P,Buschmann C,Storm C,Nee J,Parwani AS,Huemer M,Attanasio P,Boldt LH,Rauch G,Kucher A,Pieske B,Haverkamp W,Blaschke F

更新日期：2018-06-19 00:00:00

abstract：:Plasma and lipoprotein cholesterol and triglyceride concentrations were measured in Pima Indians, a genetically homogeneous population with a high prevalence of obesity and diabetes and a low frequency of coronary heart disease. The data for nondiabetic Pima Indians were compared with those of U.S. Caucasians measured...

journal_title：Circulation

authors： Howard BV,Davis MP,Pettitt DJ,Knowler WC,Bennett PH

更新日期：1983-10-01 00:00:00

abstract：:Exercise trials in cardiology are often hindered by inconsistent approaches to exercise testing. These inconsistencies include the choice of exercise protocol, exercise end points, points of analysis, and absence or misuse of gas exchange data. Gas exchange techniques greatly enhance the accuracy with which cardiopulm...

journal_title：Circulation

authors： Myers J,Froelicher VF

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND:Multiple excitation wavelets are present during ventricular fibrillation (VF). The underlying wavelet organization of VF is unclear. Phase singularities (PSs)-locations of ambiguous activation state-underlie reentry and wavelet splitting and represent the sources of VF. Understanding the mechanisms of PS for...

journal_title：Circulation

authors： Valderrábano M,Chen PS,Lin SF

更新日期：2003-07-22 00:00:00

abstract：BACKGROUND:After regular coronary balloon angioplasty, it would be helpful to identify those patients who have a low cardiac event rate. Coronary angiography alone is not sensitive enough for that purpose, but it has been suggested that the combination of optimal angiographic and optimal functional results indicates a ...

journal_title：Circulation

authors： Bech GJ,Pijls NH,De Bruyne B,Peels KH,Michels HR,Bonnier HJ,Koolen JJ

更新日期：1999-02-23 00:00:00