Hemodynamic effects of atrial pacing and prenalterol infusion in patients taking beta-adrenergic blocking drugs.

abstract：BACKGROUND:Increased common carotid artery intima-media thickness (CCA-IMT) is a marker of early atherosclerosis. Low-grade inflammation is associated with the pathogenesis of atherosclerosis. Low-grade inflammation and increased CCA-IMT are observed in end-stage renal disease (ESRD). Oxidative stress is involved in ur...

journal_title：Circulation

authors： Drüeke T,Witko-Sarsat V,Massy Z,Descamps-Latscha B,Guerin AP,Marchais SJ,Gausson V,London GM

更新日期：2002-10-22 00:00:00

abstract：BACKGROUND:Heat shock protein (HSP)60 is an abundant protein found primarily in the mitochondria, though 15% to 20% is found in the cytosol. Previously we observed that HSP60 complexes with bax in the cytosol. Reduction in HSP60 precipitates translocation of bax to the mitochondria and apoptosis. We hypothesized that H...

journal_title：Circulation

authors： Gupta S,Knowlton AA

更新日期：2002-11-19 00:00:00

abstract：:To determine whether cardiac transplant rejection can be detected noninvasively with indium-111 (111In)-labeled lymphocytes, we studied 11 dogs with thoracic heterotopic cardiac transplants without immunosuppression and five dogs with transplants treated with cyclosporine (10 mg/kg/day) and prednisone (1 mg/kg/day). A...

journal_title：Circulation

authors： Eisen HJ,Eisenberg SB,Saffitz JE,Bolman RM 3rd,Sobel BE,Bergmann SR

更新日期：1987-04-01 00:00:00

abstract：BACKGROUND:Whether knowledge of genetic risk for coronary heart disease (CHD) affects health-related outcomes is unknown. We investigated whether incorporating a genetic risk score (GRS) in CHD risk estimates lowers low-density lipoprotein cholesterol (LDL-C) levels. METHODS AND RESULTS:Participants (n=203, 45-65 year...

journal_title：Circulation

authors： Kullo IJ,Jouni H,Austin EE,Brown SA,Kruisselbrink TM,Isseh IN,Haddad RA,Marroush TS,Shameer K,Olson JE,Broeckel U,Green RC,Schaid DJ,Montori VM,Bailey KR

更新日期：2016-03-22 00:00:00

abstract：BACKGROUND:The association of anticardiolipin (aCL) antibodies with coronary artery disease has been shown in several studies but remains controversial. We evaluated the association of aCL and anti-beta(2)-glycoprotein I (abeta(2)GPI) antibodies with the risk of recurrent cardiac events in postinfarction patients. MET...

journal_title：Circulation

authors： Bili A,Moss AJ,Francis CW,Zareba W,Watelet LF,Sanz I

更新日期：2000-09-12 00:00:00

abstract：BACKGROUND:Emerging studies suggest that early administration of dual antiplatelet therapy may be better than monotherapy for prevention of early recurrent stroke and cardiovascular outcomes in acute ischemic stroke and transient ischemic attack (TIA). We performed a meta-analysis of randomized, controlled trials evalu...

journal_title：Circulation

authors： Wong KS,Wang Y,Leng X,Mao C,Tang J,Bath PM,Markus HS,Gorelick PB,Liu L,Lin W,Wang Y

更新日期：2013-10-08 00:00:00

abstract：BACKGROUND:Adverse cardiovascular events associated with thrombotic occlusion occur in 4% to 12.8% of patients after coronary angioplasty. Recently, potent antiplatelet agents have been used to reduce those thrombotic complications. Tirofiban is a highly selective, short-acting inhibitor of fibrinogen binding to platel...

journal_title：Circulation

authors：

更新日期：1997-09-02 00:00:00

abstract：BACKGROUND:Cardiac-targeted expression of truncated K(v)4.2 subunit (K(v)4.2N) reduces transient outward current (I(to)) density, prolongs action potentials (APs), and enhances contractility in 3- to 4-week-old transgenic mice. By 13 to 15 weeks of age, these mice develop severely impaired cardiac function and signs of...

journal_title：Circulation

authors： Sah R,Oudit GY,Nguyen TT,Lim HW,Wickenden AD,Wilson GJ,Molkentin JD,Backx PH

更新日期：2002-04-16 00:00:00

abstract：:We have monitored ambulant intra-arterial blood pressure with the Oxford system in six subjects with autonomic failure who exhibited postural hypotension. Plotting pooled hourly mean values we have demonstrated a consistent circadian trend in blood pressure that was the inverse of the normal pattern, with the highest ...

journal_title：Circulation

authors： Mann S,Altman DG,Raftery EB,Bannister R

更新日期：1983-09-01 00:00:00

abstract：BACKGROUND:Biventricular direct cardiac compression (DCC) can potentially support the failing heart without the complications associated with a blood/device interface. The effect of uniform DCC on left and right ventricular performance was evaluated in 7 isolated canine heart preparations. METHODS AND RESULTS:A comput...

journal_title：Circulation

authors： Artrip JH,Wang J,Leventhal AR,Tsitlik JE,Levin HR,Burkhoff D

更新日期：1999-04-27 00:00:00

abstract：BACKGROUND:In heart failure (HF), aldosterone has been implicated in the formation of reactive interstitial fibrosis, a maladaptation that contributes to left ventricular (LV) remodeling. Eplerenone is a novel selective aldosterone blocker. The present study examined the effects of long-term monotherapy with eplerenone...

journal_title：Circulation

authors： Suzuki G,Morita H,Mishima T,Sharov VG,Todor A,Tanhehco EJ,Rudolph AE,McMahon EG,Goldstein S,Sabbah HN

更新日期：2002-12-03 00:00:00

abstract：:The morphologic consequences of transluminal angioplasty of stenotic atherosclerotic coronary arteries are unknown. This study describes the production of aortoiliac atherosclerosis in rabbits and reports the morphologic changes after transluminal angioplasty of stenotic arterial lesions. Atherosclerotic lesions were ...

journal_title：Circulation

authors： Block PC,Baughman KL,Pasternak RC,Fallon JT

更新日期：1980-04-01 00:00:00

abstract：:In this report we describe electrophysiologic and histologic findings in hearts and endocardially resected preparations from patients with sustained ventricular tachycardias in the chronic phase of myocardial infarction. We recorded simultaneously from 64 endocardial sites during tachycardia in 72 patients that were o...

journal_title：Circulation

authors： de Bakker JM,van Capelle FJ,Janse MJ,Wilde AA,Coronel R,Becker AE,Dingemans KP,van Hemel NM,Hauer RN

更新日期：1988-03-01 00:00:00

abstract：:This essay reviews the founding and early history of the Council on Clinical Cardiology of the American Heart Association (AHA), the largest of the AHA's 14 councils. Based on archival research, it stresses the factors that led to the council's formation and shaped its agenda. The council was established in the contex...

journal_title：Circulation

authors： Fye WB

更新日期：1993-03-01 00:00:00

abstract：:Real-time cross-sectional echocardiographic studies of the main coronary arteries were performed in 20 normal subjects, 12 patients with patent ductus arteriosus and 14 patients with coronary artery fistula in whom the diagnosis was established by angiography. In 12 patients, the coronary artery that formed the fistul...

journal_title：Circulation

authors： Yoshikawa J,Katao H,Yanagihara K,Takagi Y,Okumachi F,Yoshida K,Tomita Y,Fukaya T,Baba K

更新日期：1982-03-01 00:00:00

abstract：BACKGROUND:Antiplatelet agents presently used in the secondary prevention of cardiovascular disease fail to prevent the majority of cases of recurrent stroke and systemic embolization. An evaluation of the efficacy of new agents is hampered by a lack of in vivo models in humans. Asymptomatic cerebral embolic signals (E...

journal_title：Circulation

authors： Molloy J,Martin JF,Baskerville PA,Fraser SC,Markus HS

更新日期：1998-10-06 00:00:00

abstract：BACKGROUND:Recent studies have suggested that endogenous erythropoietin (Epo) plays an important role in the mobilization of bone marrow-derived endothelial progenitor cells (EPCs). However, it remains to be elucidated whether the Epo system exerts protective effects on pulmonary hypertension (PH), a fatal disorder enc...

journal_title：Circulation

authors： Satoh K,Kagaya Y,Nakano M,Ito Y,Ohta J,Tada H,Karibe A,Minegishi N,Suzuki N,Yamamoto M,Ono M,Watanabe J,Shirato K,Ishii N,Sugamura K,Shimokawa H

更新日期：2006-03-21 00:00:00

abstract：:Malignant hyperthermia is a disease resulting from defective cellular membranes, usually presenting as drug-induced pyrexic crises. We describe four patients with life threatening ventricular arrhythmias or chest pain in the absence of pyrexic crises. Three presented with life threatening arrhythmias and the fourth wi...

journal_title：Circulation

authors： Huckell VF,Staniloff HM,Britt BA,Waxman MB,Morch JE

更新日期：1978-11-01 00:00:00

abstract：BACKGROUND:The role of infections and inflammation in the pathophysiology of coronary heart disease is emerging. We studied the independent and joint effects of these 2 components on coronary risk. METHODS AND RESULTS:We measured baseline levels of C-reactive protein (CRP) and antibodies to adenovirus, enterovirus, cy...

journal_title：Circulation

authors： Roivainen M,Viik-Kajander M,Palosuo T,Toivanen P,Leinonen M,Saikku P,Tenkanen L,Manninen V,Hovi T,Mänttäri M

更新日期：2000-01-25 00:00:00

abstract：BACKGROUND:Although early trials indicate the treatment of restenosis with radiation therapy is safe and effective, the long-term impact of this new technology has been questioned. The possibility of late untoward consequences, such as aneurysm formation, perforation, and accelerated vascular disease, is of significant...

journal_title：Circulation

authors： Teirstein PS,Massullo V,Jani S,Russo RJ,Cloutier DA,Schatz RA,Guarneri EM,Steuterman S,Sirkin K,Norman S,Tripuraneni P

更新日期：1999-01-19 00:00:00

abstract：BACKGROUND:Excessive proliferation and apoptosis resistance of pulmonary artery smooth muscle cells (PASMCs) are key mechanisms of pulmonary arterial hypertension (PAH). Despite the multiple combination therapy, a considerable number of patients develop severe pulmonary hypertension (PH) because of the lack of diagnost...

journal_title：Circulation

authors： Kikuchi N,Satoh K,Kurosawa R,Yaoita N,Elias-Al-Mamun M,Siddique MAH,Omura J,Satoh T,Nogi M,Sunamura S,Miyata S,Saito Y,Hoshikawa Y,Okada Y,Shimokawa H

更新日期：2018-08-07 00:00:00

abstract：BACKGROUND:Physical activity is associated with lower risk of cardiovascular disease, but the mechanisms are uncertain. Hemostatic and inflammatory markers have been linked with risk of cardiovascular disease. We therefore examined the relationship between physical activity and hemostatic and inflammatory variables. M...

journal_title：Circulation

authors： Wannamethee SG,Lowe GD,Whincup PH,Rumley A,Walker M,Lennon L

更新日期：2002-04-16 00:00:00

abstract：BACKGROUND:Several authors have reported cases in which 201Tl scintigraphy demonstrated perfusion abnormality in the septum of patients with left bundle branch block (LBBB) and normal coronary arteriogram. The mechanism of this abnormality, however, remains to be clarified. METHODS AND RESULTS:To determine whether LBB...

journal_title：Circulation

authors： Ono S,Nohara R,Kambara H,Okuda K,Kawai C

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND:Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly used to treat cardiogenic shock. However, VA-ECMO might hamper myocardial recovery. The Impella unloads the left ventricle. This study aimed to evaluate whether left ventricular unloading in patients with cardiogenic shock treated wit...

journal_title：Circulation

authors： Schrage B,Becher PM,Bernhardt A,Bezerra H,Blankenberg S,Brunner S,Colson P,Cudemus Deseda G,Dabboura S,Eckner D,Eden M,Eitel I,Frank D,Frey N,Funamoto M,Goßling A,Graf T,Hagl C,Kirchhof P,Kupka D,Landmesser U,Li

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Interferons (IFNs) play an important role in antiviral defense and have therapeutic potential in coxsackievirus heart disease. However, little is known about the relative contributions of type I and type II IFN signaling in coxsackievirus B3 (CVB3) infection or their role in the cardioselective nature of CVB...

journal_title：Circulation

authors： Wessely R,Klingel K,Knowlton KU,Kandolf R

更新日期：2001-02-06 00:00:00

abstract：:We assessed factors during an initial episode of ventricular fibrillation that may be predictive of recurrence. Of 141 consecutive patients with acute ischemic heart disease who survived an initial episode of ventricular fibrillation, 41 (29%) had recurrent ventricular fibrillation during hospitalization. The incidenc...

journal_title：Circulation

authors： Logan KR,McIlwaine WJ,Adgey AA,Pantridge JF

更新日期：1981-12-01 00:00:00

abstract：BACKGROUND:In the event of rupture of an abdominal aortic aneurysm (AAA), mortality is very high. AAA prevalence and incidence of ruptures have been reported to be decreasing. The treatment of AAA has also undergone a change in recent decades with a shift toward endovascular aneurysm repair (EVAR). Our aim was to evalu...

journal_title：Circulation

authors： Laine MT,Laukontaus SJ,Sund R,Aho PS,Kantonen I,Albäck A,Venermo M

更新日期：2017-10-31 00:00:00

abstract：BACKGROUND:The T2G1s monoclonal antifibrin antibody binds specifically to fibrin but not to fibrinogen. METHODS AND RESULTS:In a canine model of acute arterial thrombosis, we determined the feasibility of imaging thrombi using a 99mTc-labeled Fab' fragment. In 14 dogs, 10 carotid and 13 femoral artery thrombi were pro...

journal_title：Circulation

authors： Cerqueira MD,Stratton JR,Vracko R,Schaible TF,Ritchie JL

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Brain natriuretic peptide (BNP) levels are used in the evaluation of patients with heart disease, yet there is little understanding of the effect of hypoxia on natriuretic peptide secretion. Furthermore, recent data suggest that oxytocin may mediate stretch-induced atrial natriuretic peptide (ANP) secretion....

journal_title：Circulation

authors： Hopkins WE,Chen Z,Fukagawa NK,Hall C,Knot HJ,LeWinter MM

更新日期：2004-06-15 00:00:00

abstract：BACKGROUND:Early childhood introduction of nutritional habits aimed at atherosclerosis prevention reduces children's serum total cholesterol concentration, but its effect on vascular endothelial function is unknown. METHODS AND RESULTS:Between 1990 and 1992, we randomized healthy 7-month-old infants (n=1062) to interv...

journal_title：Circulation

authors： Raitakari OT,Rönnemaa T,Järvisalo MJ,Kaitosaari T,Volanen I,Kallio K,Lagström H,Jokinen E,Niinikoski H,Viikari JS,Simell O

更新日期：2005-12-13 00:00:00