High-dose chemotherapy with autologous stem cell support in poor-risk germ cell tumors.

abstract：:A female patient presenting with B-CLL and coincident eosinophilia-myalgia syndrome (EMS) after ingestion of L-tryptophan is described. The manifestations of EMS disappeared completely during treatment with cyclophosphamide/prednisone. and there was an intermittent clinical remission of CLL with absence of the monoclo...

journal_title：Annals of hematology

authors： Böhme A,Wolter M,Hoelzer D

更新日期：1998-11-01 00:00:00

abstract：:A 72-year-old-man with night sweats and a low-grade fever was found to have bilateral adrenal enlargement associated with incipient adrenal insufficiency. Without any intervention, these adrenal lesions regressed spontaneously, accompanied by disappearance of clinical symptoms. Seven months later, however, the lesions...

journal_title：Annals of hematology

authors： Fujiwara T,Kawamura M,Sasaki A,Asahi H,Sasou S,Itoh S,Hiramori K

更新日期：2001-09-01 00:00:00

abstract：:Immune thrombocytopenia (ITP) is characterised by a transient or persistent decrease in platelets accompanied by an increased risk of bleeding, which can have a significant negative impact on patients' health-related quality of life. The condition has long been associated with an increased rate of immune-mediated plat...

journal_title：Annals of hematology

authors： Kühne T,Imbach P

更新日期：2010-07-01 00:00:00

abstract：:Early cytomegalovirus (CMV) replication (eCMV) after allogeneic hematopoietic stem cell transplantation (allo-HSCT) has been suggested as an independent factor that reduces leukemia relapse risk. We retrospectively analyzed 74 patients with acute myeloid leukemia (AML) who underwent allo-HSCT between August 2006 and S...

journal_title：Annals of hematology

authors： Jang JE,Kim SJ,Cheong JW,Hyun SY,Kim YD,Kim YR,Kim JS,Min YH

更新日期：2015-02-01 00:00:00

abstract：:Sickle cell disease (SCD) is a relatively common inherited hemolytic anemia among individuals of African descent. Genetic factors might clarify clinical diversity of the disease and variations in treatment response. Some researchers investigated heme oxygenase-1 (HMOX1) or chemokine receptor 5 (CCR5Δ32) genotypes amon...

journal_title：Annals of hematology

authors： Bakr S,Khorshied M,Talha N,Jaffer KY,Soliman N,Eid K,El-Ghamrawy M

更新日期：2019-08-01 00:00:00

abstract：:The aim of this review is to summarize the current knowledge on the clinical results of biotherapy of chronic myelogenous leukemia (CML) and potential mechanisms of the antitumor action of interferon alpha. IFN alpha treatment induces hematologic and cytogenetic remissions in patients with chronic phase CML. In additi...

journal_title：Annals of hematology

authors： Aulitzky WE,Peschel C,Schneller F,Huber C

更新日期：1995-03-01 00:00:00

abstract：:We report about a 28-year-old woman with relapsed mantle cell lymphoma (MCL, centrocytic lymphoma according to the Kiel classification) refractory to salvage chemotherapy. The patient underwent allogeneic bone marrow transplantation from a HLA-identical brother after myeloablative chemotherapy consisting of busulfan, ...

journal_title：Annals of hematology

authors： Kröger N,Hoffknecht M,Krüger W,Zeller W,Renges H,Stute N,Zschaber R,Zander AR

更新日期：2000-10-01 00:00:00

abstract：:This retrospective study evaluated the benefit of alemtuzumab monotherapy in unselected patients with advanced B-cell chronic lymphocytic leukemia (CLL) and prolymphocytic leukemia (B-PLL) to definitely describe the impact of this antibody in clinical routine use. Data were collected from 208 consecutive, mainly pretr...

journal_title：Annals of hematology

authors： Fiegl M,Stauder R,Steurer M,Mian M,Hopfinger G,Brychtova Y,Skrabs C,Zabernigg A,Schmid F,Haslbaur F,Winder G,Walder A,Lang A,Voskova D,Greil R,Mayer J,Gastl G,Austrian Collaborative Study Group on Alemtuzumab in Chronic

更新日期：2014-02-01 00:00:00

abstract：:The anti-CD38 monoclonal antibody daratumumab is approved as a single agent for the treatment of patients with relapsed and refractory multiple myeloma (RRMM) who have received at least three prior lines of therapy, including a proteasome inhibitor (PI) and an immunomodulatory agent (IMID), or who are double refractor...

journal_title：Annals of hematology

authors： Jullien M,Trudel S,Tessoulin B,Mahé B,Dubruille V,Blin N,Gastinne T,Bonnet A,Lok A,Lebourgeois A,Peterlin P,Garnier A,Chevalier P,Guillaume T,Thomaré P,Le Gouill S,Moreau P,Touzeau C

更新日期：2019-06-01 00:00:00

abstract：:Overproduction of proinflammatory cytokines is characteristic of hemophagocytic syndrome (HPS), a highly lethal inflammatory disease. Peripheral blood monocytes include two distinct subpopulations according to surface antigen expression: a major type, CD14(+)/CD16(-) (classical monocytes), and a minor type, CD14(+)/CD...

journal_title：Annals of hematology

authors： Takeyama N,Yabuki T,Kumagai T,Takagi S,Takamoto S,Noguchi H

更新日期：2007-11-01 00:00:00

abstract：:In this report we show that serum has differentiation-inducing effects on primitive hematopoietic progenitor cells with the CD34++CD38- immunophenotype. Using the pre-colony forming unit (pre-CFU) assay as a model for early myelopoiesis, we compared the effects of serum-containing and serum-free media and evaluated di...

journal_title：Annals of hematology

authors： Willems R,Henckaerts E,Lenjou M,Nijs G,Rodrigus I,Moulijn AC,Slegers H,Berneman ZN,Van Bockstaele DR

更新日期：2001-01-01 00:00:00

abstract：:Spontaneous splenic rupture is a rare, though life-threatening complication of some hematological malignancies and is even more infrequent as the initial symptom of acute lymphoblastic leukemia. We describe the fourth case, to our knowledge, of acute lymphoblastic leukemia presenting as splenic rupture, and for the fi...

journal_title：Annals of hematology

authors： Altès A,Brunet S,Martinez C,Soler J,Ayats R,Sureda A,López R,Domingo A

更新日期：1994-03-01 00:00:00

abstract：:Platelet function disorders (PFD) and Von Willebrand disease (VWD) are among the uncommon causes of bleeding in haematological practice. The inherited variety of PFD includes defects in platelet adhesion, aggregation, secretion and platelet procoagulant activities. VWD is classified into three major categories-type 1 ...

journal_title：Annals of hematology

authors： Gupta PK,Charan VD,Saxena R

更新日期：2007-06-01 00:00:00

abstract：:An analysis was conducted in four members of the same family, two of whom had a history of severe bleeding associated with type 2B von Willebrand's disease (VWD) which, although found to be due to the same mutation, nevertheless exhibited different phenotype patterns in the two subjects involved. Von Willebrand's fact...

journal_title：Annals of hematology

authors： Rendal E,Penas N,Larrabeiti B,Pérez A,Vale A,López-Fernández MF,Batlle J

更新日期：2001-06-01 00:00:00

abstract：:Extramedullary (e) relapse in multiple myeloma(MM) has an adverse prognosis, but knowledge concerning biological features and preferred treatment is scarce. We screened the myeloma registry of our institution for eMM relapses and identified 24 cases among 357 patients (pts).Only 8% of eMM relapses occurred after initi...

journal_title：Annals of hematology

authors： Rasche L,Bernard C,Topp MS,Kapp M,Duell J,Wesemeier C,Haralambieva E,Maeder U,Einsele H,Knop S

更新日期：2012-07-01 00:00:00

abstract：:The Wilms' tumor 1 (WT1) expression has been recognized in a substantial number of acute myeloid leukemia (AML) patients. Some studies indicated the association of diagnosed WT1 higher expression (WT1(H)) and poor outcome in the AML patients, while other studies had different opinions. Therefore, we performed a meta-a...

journal_title：Annals of hematology

authors： Yi-Ning Y,Xiao-rui W,Chu-xian Z,Chun W,You-wen Q

更新日期：2015-06-01 00:00:00

abstract：:Fanconi anemia (FA) is a DNA repair disorder resulting from mutations in genes encoding for FA DNA repair complex components and is characterized by variable congenital abnormalities, bone marrow failure (BMF), and high incidences of malignancies. FA mosaicism arises from reversion or other compensatory mutations in h...

journal_title：Annals of hematology

authors： Nicoletti E,Rao G,Bueren JA,Río P,Navarro S,Surrallés J,Choi G,Schwartz JD

更新日期：2020-05-01 00:00:00

abstract：PURPOSE:To determine whether, after very intensive induction and consolidation therapy in childhood AML, further maintenance therapy (MT) confers any advantage. PATIENTS AND METHODS:Three hundred-nine children with previously untreated AML were registered in the LAME 89/91 protocol. This three-cycle intensive regimen ...

journal_title：Annals of hematology

authors： Perel Y,Auvrignon A,Leblanc T,Michel G,Vannier JP,Dalle JH,Gandemer V,Schmitt C,Mèchinaud F,Lamagnere JP,Piguet Ch,Couillaud G,Pautard B,Baruchel A,Leverger G,Group LAME.,French Society of Pediatric Hematology and Immunol

更新日期：2004-01-01 00:00:00

abstract：:We monitored platelet activation by means of P-selectin and platelet monocyte aggregates (PMA) and platelet function by whole blood multiple electrode aggregometry and platelet adhesion under high shear in chronic immune thrombocytopenia patients to define changes in platelet activation during treatment with eltrombop...

journal_title：Annals of hematology

authors： Haselboeck J,Pabinger I,Ay C,Koder S,Panzer S

更新日期：2012-01-01 00:00:00

abstract：:Neutropenic enterocolitis (NE) is a severe gastrointestinal complication in patients who undergo aggressive chemotherapy. It is a necrotizing inflammation of the cecum, colon, and the terminal part of the ileum. The serious clinical state of NE patients requires very frequent surgical consultations; however, in a few ...

journal_title：Annals of hematology

authors： Wach M,Dmoszynska A,Wasik-Szczepanek E,Pozarowski A,Drop A,Szczepanek D

更新日期：2004-08-01 00:00:00

abstract：:Hemophagocytic lymphohistiocytosis (HLH) is a rare multisystem disorder characterized by proliferation and diffuse infiltration multiple organs with histiocytes, including the central nervous system (CNS). Neurological manifestations of HLH have been recognized in different studies with children, but they remain relat...

journal_title：Annals of hematology

authors： Cai G,Wang Y,Liu X,Han Y,Wang Z

更新日期：2017-08-01 00:00:00

abstract：:The best treatment option for patients with relapsed or high-grade follicular lymphoma (FL) is unknown. In spite of major advances in the therapy for FL, disease-free survival remains short, and median time to progression is just over a year. Autologous stem cell transplantation in patients with relapsed FL is safe an...

journal_title：Annals of hematology

authors： Ganguly S,Divine CL,Deauna-Limayo D,Bodensteiner DC,Cook JD,Lewis JN,Skikne BS

更新日期：2005-08-01 00:00:00

abstract：:In the present study, we questioned whether the cholesterol synthesis inhibitor lovastatin potentiates the cytotoxicity of chemotherapeutic agents in the primitive CD34(+) subpopulation of acute myeloid leukemia (AML) cells. AML mononuclear cells (n = 17) were sorted in CD34(+) and CD34(-) fractions and compared to no...

journal_title：Annals of hematology

authors： de Jonge-Peeters SD,van der Weide K,Kuipers F,Sluiter WJ,de Vries EG,Vellenga E

更新日期：2009-06-01 00:00:00

abstract：:Second-generation azoles may be more effective than first-generation azoles in the prevention of fungal infections in hematology patients. We performed a systematic review with meta-analysis of randomized controlled trials comparing second- with first-generation azoles in hematology patients with respect to proven or ...

journal_title：Annals of hematology

authors： Ping B,Zhu Y,Gao Y,Yue C,Wu B

更新日期：2013-06-01 00:00:00

abstract：:Mutations in the HFE gene result in iron overload and can produce hereditary hemochromatosis (HH), a disorder of iron metabolism characterized by increased intestinal iron absorption. Dietary quality, alcoholism and other life-style factors can increase the risk of iron overload, especially among genetically at risk p...

journal_title：Annals of hematology

authors： Aranda N,Viteri FE,Montserrat C,Arija V

更新日期：2010-08-01 00:00:00

abstract：:A 57-year-old man with acute myeloid leukemia (AML) French-American-British (FAB) 4 developed disseminated invasive cerebral and pulmonary aspergillosis during postinduction aplasia. According to international consensus, infection was categorized as probable (two host factors: deep neutropenia for >10 days and refract...

journal_title：Annals of hematology

authors： Damaj G,Ivanov V,Le Brigand B,D'incan E,Doglio MF,Bilger K,Faucher C,Vey N,Gastaut JA

更新日期：2004-06-01 00:00:00

abstract：:Raised percentage hypochromic red cells (%HRC) were detected at diagnosis in 10 of 34 consecutive patients with low-risk myelodysplastic syndrome (MDS) [refractory anemia (RA) (4/26) and RA with ring sideroblasts (6/8)], all of whom had normal or increased serum ferritin and bone marrow iron stores. Elevated %HRC has ...

journal_title：Annals of hematology

authors： Murphy PT,Quinn JP,O'Donghaile D,Swords R,O'Donnell JR

更新日期：2006-07-01 00:00:00

abstract：:The aim of the study was to investigate whether the well-known high anemia prevalence in pregnant women from the eastern Mediterranean and Asian regions decreased when the women immigrated to a low-frequency region (Denmark). During 70 months, 1,741 pregnant immigrant women referred from primary care to an obligatory ...

journal_title：Annals of hematology

authors： Nybo M,Friis-Hansen L,Felding P,Milman N

更新日期：2007-09-01 00:00:00

abstract：:Acute leukemia (AL) patients may experience more than one episode of bloodstream infection (BSI) caused by the same pathogen during the entire chemotherapy program. In order to identify factors influencing BSI recurrence (R-BSI) during subsequent phases of treatment, we analyzed all BSIs occurring to consecutively tre...

journal_title：Annals of hematology

authors： Cattaneo C,Antoniazzi F,Tumbarello M,Skert C,Borlenghi E,Schieppati F,Cerqui E,Pagani C,Petullà M,Re A,Rossi G

更新日期：2014-05-01 00:00:00

abstract：:Post-transplantation cyclophosphamide (PTCy) demonstrated effectiveness to prevent GVHD after haploidentical hematopoietic cell transplantation (HCT). Reducing toxicities with a maximized efficacy is still challenging in HCT. In this retrospective study, we analyzed the safety and efficacy of transplantation from a 1-...

journal_title：Annals of hematology

authors： Soltermann Y,Heim D,Medinger M,Baldomero H,Halter JP,Gerull S,Arranto C,Passweg JR,Kleber M

更新日期：2019-06-01 00:00:00