Features of extramedullary myeloma relapse: high proliferation, minimal marrow involvement, adverse cytogenetics: a retrospective single-center study of 24 cases.

abstract：:Acute Epstein-Barr virus (EBV) infection commonly induces hematological abnormalities, most notably atypical lymphocytosis ("infectious mononucleosis"). In addition, mild decreases in platelet counts are commonly encountered in uncomplicated cases; however, severe thrombocytopenia is exceedingly rare. Here, we describ...

journal_title：Annals of hematology

authors： Walter RB,Hong TC,Bachli EB

更新日期：2002-11-01 00:00:00

abstract：:Previous studies exploring associations between statin use and risk of multiple myeloma (MM) showed inconsistent results. We searched for articles published in English in databases (PubMed, Web of Science, EMBASE, Medline, and Google Scholar) before October 2019. The multivariate odds ratio (OR)/relative risk (RR) and...

journal_title：Annals of hematology

authors： Zhang P,Liu B

更新日期：2020-08-01 00:00:00

abstract：:Post-transplantation cyclophosphamide (PTCy) demonstrated effectiveness to prevent GVHD after haploidentical hematopoietic cell transplantation (HCT). Reducing toxicities with a maximized efficacy is still challenging in HCT. In this retrospective study, we analyzed the safety and efficacy of transplantation from a 1-...

journal_title：Annals of hematology

authors： Soltermann Y,Heim D,Medinger M,Baldomero H,Halter JP,Gerull S,Arranto C,Passweg JR,Kleber M

更新日期：2019-06-01 00:00:00

abstract：:Hydroxyurea is increasingly being used to control myeloproliferative disorders, in part because of its relative lack of side effects. We present a case of life-threatening alveolitis in a patient treated with hydroxyurea for myeloproliferative syndrome. Absence of exposure to other drugs and the clinical course sugges...

journal_title：Annals of hematology

authors： Hennemann B,Bross KJ,Reichle A,Andreesen R

更新日期：1993-09-01 00:00:00

abstract：:Therapy-induced autoimmunity may mediate the destruction of cancer cells. Previous studies have demonstrated that presence of autoimmune thyroid disorder is associated with favorable outcome in patients with solid cancer. Patients with diffuse large B cell lymphoma (DLBCL) who achieved complete response on positron em...

journal_title：Annals of hematology

authors： Song MK,Chung JS,Kim SJ,Kim SS,Shin HJ

更新日期：2015-06-01 00:00:00

abstract：:Gastric MALT lymphoma is closely associated with Helicobacter pylori infection. Bacterial eradication therapy comprising clarithromycin is the first-line treatment in gastric MALT lymphoma patients. However, antimicrobial resistance to clarithromycin has been increasing in Europe, and thus far, it has not been examine...

journal_title：Annals of hematology

authors： Bilgilier C,Simonitsch-Klupp I,Kiesewetter B,Raderer M,Dolak W,Makristathis A,Steininger C

更新日期：2016-06-01 00:00:00

abstract：:The general objective of this study was to evaluate the risks of agranulocytosis and aplastic anemia in relation to drug use. Other potential risk factors, including history of infectious mononucleosis, were also evaluated. In an international population-based case-control study, cases of agranulocytosis and aplastic ...

journal_title：Annals of hematology

authors： Levy M,Kelly JP,Kaufman DW,Shapiro S

更新日期：1993-10-01 00:00:00

abstract：:Elderly and infirm patients with acute myeloid leukemia (AML) with either induction refractory or relapse disease may benefit from treatment with azacitidine. We retrospectively reviewed the data from five tertiary centers in Israel, treated between 2009 and 2015. Thirty-four patients (median age 74 years) were identi...

journal_title：Annals of hematology

authors： Ram R,Gatt M,Merkel D,Helman I,Inbar T,Nagler A,Avivi I,Ofran Y

更新日期：2017-04-01 00:00:00

abstract：:B cell acute lymphoblastic leukemia (B-ALL) is an aggressive hematologic malignancy with limited treatment strategies. Histone deacetylases inhibitors (HDACis) are promising novel tools for cancer therapy, whose anti-tumor effects and the underlying mechanisms on B-ALL remain to be elucidated. Recently, Notch1 signali...

journal_title：Annals of hematology

authors： Shao N,Ma D,Wang J,Lu T,Guo Y,Ji C

更新日期：2013-01-01 00:00:00

abstract：:MicroRNAs are a class of small non-coding RNAs that are 19-22 nucleotides in length and regulate a variety of biological processes at the post-transcriptional level. MicroRNA dysregulation disrupts normal biological processes, resulting in tumorigenesis. Acute myeloid leukemia is an invasive hematological malignancy c...

journal_title：Annals of hematology

authors： Li M,Cui X,Guan H

更新日期：2020-03-01 00:00:00

abstract：:Interferon alpha (IFN) inhibits the growth of the abnormal clone in patients with myeloproliferative disorders, leading to a reduction of the clinical and laboratory signs of the pathologic myeloproliferation. The therapeutic efficacy of IFN in polycythemia vera (PV) is demonstrated by the summarized treatment results...

journal_title：Annals of hematology

authors： Lengfelder E,Berger U,Hehlmann R

更新日期：2000-03-01 00:00:00

abstract：:A patient with a lymphoid blast crisis of a chronic myelogenous leukemia (CML) was treated with vindesine, vincristine and prednisone. Blasts disappeared from the peripheral blood but persisted at a level of 60% in the bone marrow. After 5 weeks of continuous therapy, the patient became thrombopenic, and 2 weeks later...

journal_title：Annals of hematology

authors： Fink M

更新日期：1994-02-01 00:00:00

abstract：:To determine the value of aerosol amphotericin B inhalations for prevention of invasive pulmonary aspergillosis (IPA), we initiated a prospective randomized multicenter trial. The scheduled intent-to-treat interim analysis included 115 patients (30%) with prolonged neutropenia after chemotherapy for acute myeloid leuk...

journal_title：Annals of hematology

authors： Behre GF,Schwartz S,Lenz K,Ludwig WD,Wandt H,Schilling E,Heinemann V,Link H,Trittin A,Boenisch O

更新日期：1995-12-01 00:00:00

abstract：:This paper describes six Indian families in which silent-gene beta-thalassemia was encountered by us in the past 2 years. This stresses the importance of globin-chain synthesis in the diagnosis of beta-thalassemia. Of these six cases, five were diagnosed retrospectively when they had a homozygous beta-thalassemia offs...

journal_title：Annals of hematology

authors： Nadkarni A,Pawar A,Mudera VC,Mohanty D,Colah R

更新日期：1995-01-01 00:00:00

abstract：:Parainfluenza virus (PIV) infection is a significant cause of morbidity and mortality, especially in hematologic malignancy patients including hematopoietic stem cell transplantation (HCT) recipients. However, limited information is available for risk stratification in PIV-infected patients with hematologic malignancy...

journal_title：Annals of hematology

authors： Lee J,Jung J,Kim MJ,Chong YP,Lee SO,Choi SH,Kim YS,Woo JH,Choi EJ,Park HS,Lee JH,Lee JH,Lee KH,Kim SH

更新日期：2020-06-01 00:00:00

abstract：:Azacitidine and decitabine, two hypomethylating agents, are known to be effective in the treatment of high-risk myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) patients who cannot endure intensive cytotoxic chemotherapy or are not eligible for transplantation. However, the treatment response rate is l...

journal_title：Annals of hematology

authors： Wang H,Li Y,Lv N,Li Y,Wang L,Yu L

更新日期：2018-11-01 00:00:00

abstract：:Overproduction of proinflammatory cytokines is characteristic of hemophagocytic syndrome (HPS), a highly lethal inflammatory disease. Peripheral blood monocytes include two distinct subpopulations according to surface antigen expression: a major type, CD14(+)/CD16(-) (classical monocytes), and a minor type, CD14(+)/CD...

journal_title：Annals of hematology

authors： Takeyama N,Yabuki T,Kumagai T,Takagi S,Takamoto S,Noguchi H

更新日期：2007-11-01 00:00:00

abstract：:In follicular lymphoma the t(14;18) might be useful as a tumor marker in predicting the quality of the response to treatment. We investigated whether analyzing numbers of t(14;18)-positive cells in peripheral blood correlated with remission status in individual patients receiving a variety of treatments. Numbers of ci...

journal_title：Annals of hematology

authors： Mandigers CM,Meijerink JP,van 't Veer MB,Mensink EJ,Raemaekers JM

更新日期：2003-12-01 00:00:00

abstract：:Thrombotic thrombocytopenic purpura (TTP) is a hematologic disorder which is clinically characterized by thrombocytopenia, microangiopathic hemolytic anemia, fever, neurologic symptoms, and cardiac and renal involvement. The pathogenic mechanisms of this disease are poorly understood. It is well known that TTP is asso...

journal_title：Annals of hematology

authors： Rozdzinski E,Hertenstein B,Schmeiser T,Seifried E,Kurrle E,Heimpel H

更新日期：1992-05-01 00:00:00

abstract：PURPOSE:The current study was initiated to assess the clinical efficacy and side effects of rituximab in patients with relapsed advanced stage follicular lymphoma. PATIENTS AND METHODS:The study was performed as an open-label non-randomized multicenter phase-II trial and included patients older than 18 years of age wi...

journal_title：Annals of hematology

authors： Feuring-Buske M,Kneba M,Unterhalt M,Engert A,Gramatzki M,Hiller E,Trümper L,Brugger W,Ostermann H,Atzpodien J,Hallek M,Aulitzky E,Hiddemann W

更新日期：2000-09-01 00:00:00

abstract：:We found increased numbers of CD28-negative T cells in a patient with multicentric Castleman's disease (MCD), who also had significantly decreased interleukin-2 (IL-2) production and impaired T-cell proliferation. The presence of CD28-negative T cells may be indicative of a functional T-cell defect in MCD. ...

journal_title：Annals of hematology

authors： Ishiyama T,Koike M,Kakimoto T,Akimoto Y,Tsuruoka N

更新日期：1996-10-01 00:00:00

abstract：:We monitored platelet activation by means of P-selectin and platelet monocyte aggregates (PMA) and platelet function by whole blood multiple electrode aggregometry and platelet adhesion under high shear in chronic immune thrombocytopenia patients to define changes in platelet activation during treatment with eltrombop...

journal_title：Annals of hematology

authors： Haselboeck J,Pabinger I,Ay C,Koder S,Panzer S

更新日期：2012-01-01 00:00:00

abstract：:A female patient presenting with B-CLL and coincident eosinophilia-myalgia syndrome (EMS) after ingestion of L-tryptophan is described. The manifestations of EMS disappeared completely during treatment with cyclophosphamide/prednisone. and there was an intermittent clinical remission of CLL with absence of the monoclo...

journal_title：Annals of hematology

authors： Böhme A,Wolter M,Hoelzer D

更新日期：1998-11-01 00:00:00

abstract：:Myelodysplastic syndromes are usually associated with pancytopenia. Disorders involving deletion of the long arm of chromosome 5 (5q-syndrome) and, rarely, patients with karyotypic abnormalities involving chromosome 3 associated with abnormal thrombopoiesis may have a normal or even raised platelet count. Other cytoge...

journal_title：Annals of hematology

authors： Patel K,Kelsey P

更新日期：1997-04-01 00:00:00

abstract：:The best treatment option for patients with relapsed or high-grade follicular lymphoma (FL) is unknown. In spite of major advances in the therapy for FL, disease-free survival remains short, and median time to progression is just over a year. Autologous stem cell transplantation in patients with relapsed FL is safe an...

journal_title：Annals of hematology

authors： Ganguly S,Divine CL,Deauna-Limayo D,Bodensteiner DC,Cook JD,Lewis JN,Skikne BS

更新日期：2005-08-01 00:00:00

abstract：:Autoantibody against erythrocytes has occasionally been observed in patients with de novo acute myelocytic leukemia (AML). However, it is not clear whether this autoantibody in AML patients induces frank hemolysis (autoimmune hemolytic anemia, AIHA), as seen in lymphoid neoplasms. We present two de novo AML patients w...

journal_title：Annals of hematology

authors： Tamura H,Ogata K,Yokose N,An E,Kamikubo K,Dan K,Kajii E,Nomura T

更新日期：1996-01-01 00:00:00

abstract：:The aim of the present study was to investigate the prevalence of chronic idiopathic neutropenia of adults (CINA) among an apparently healthy population born and living on the island of Crete. The study was carried out with 778 subjects, 392 men aged 16-78 years (median 43 years) and 386 women aged 15-79 years (median...

journal_title：Annals of hematology

authors： Papadaki HA,Xylouri I,Coulocheri S,Kalmanti M,Kafatos A,Eliopoulos GD

更新日期：1999-07-01 00:00:00

abstract：:Despite high-dose chemotherapy and autografting, the outcome for patients with primary refractory Hodgkin's disease (HD) or multiple relapses remains unsatisfactory. Six pediatric patients (median age: 16 years, range: 11-19) received reduced intensity conditioning and allogeneic peripheral blood stem cell transplanta...

journal_title：Annals of hematology

authors： Claviez A,Klingebiel T,Beyer J,Nürnberger W,Ehninger G,Suttorp M,Dreger P,Dörffel W,Schmitz N

更新日期：2004-04-01 00:00:00

abstract：:Indolent primary cutaneous B cell lymphomas (PCBCL) generally have a good prognosis, but they often relapse leading in some cases to extracutaneous disease and therefore, to poor survival. We developed a prognostic model to improve the therapeutic approach to these lymphomas. Two hundred and seventeen patients with di...

journal_title：Annals of hematology

authors： Mian M,Marcheselli L,Luminari S,Federico M,Cantonetti M,Sarris AH,Rossi A,Rambaldi A,Frontani M,Devizzi L,Gianni AM,Busetto M,Berti E,Martinelli G,Tsang RW,Ferreri AJ,Pinotti G,Pogliani E,Zucca E,Cortelazzo S

更新日期：2011-04-01 00:00:00

abstract：:An analysis was conducted in four members of the same family, two of whom had a history of severe bleeding associated with type 2B von Willebrand's disease (VWD) which, although found to be due to the same mutation, nevertheless exhibited different phenotype patterns in the two subjects involved. Von Willebrand's fact...

journal_title：Annals of hematology

authors： Rendal E,Penas N,Larrabeiti B,Pérez A,Vale A,López-Fernández MF,Batlle J

更新日期：2001-06-01 00:00:00