Acute alveolitis induced by hydroxyurea in a patient with myeloproliferative syndrome.

abstract：:The efficacy of a single dose of MCNU 150 mg was evaluated in nine symptomatic patients with essential thrombocythemia (ET). As the platelet counts increased during the following 4 weeks, an extra dose of 100 mg of MCNU was administered to three patients. All patients had thrombotic or hemorrhagic complications. Seven...

journal_title：Annals of hematology

authors： Murakami H,Tamura J,Sawamura M

更新日期：1993-05-01 00:00:00

abstract：:Hematopoietic recovery after high-dose chemotherapy (HDC) in the treatment of hematological diseases may be slow and/or incomplete. This is generally attributed to progressive hematopoietic stem cell failure, although defective hematopoiesis may be in part due to poor stromal function. Chemotherapy is known to damage ...

journal_title：Annals of hematology

authors： Kemp K,Morse R,Wexler S,Cox C,Mallam E,Hows J,Donaldson C

更新日期：2010-07-01 00:00:00

abstract：:Although retreatment with alemtuzumab in relapsing B-cell chronic lymphocytic leukemia (CLL) may be beneficial, there has thus far been no thorough analysis available on this topic. Data were collected from 30 chemotherapy-pretreated patients with progressive CLL who had received alemtuzumab twice in consecutive, dist...

journal_title：Annals of hematology

authors： Fiegl M,Falkner F,Steurer M,Zojer N,Hopfinger G,Haslbauer F,Winder G,Voskova D,Andel J,Lang A,Brychtova Y,Mayer J,Greil R,Gastl G,Austrian Collaborative Study Group on Alemtuzumab in Chronic Lymphocytic Leukemia.,Czech Leuk

更新日期：2011-09-01 00:00:00

abstract：:Myelodysplastic syndromes (MDS) are hematopoietic stem cell malignancies associated with an erythroid maturation defect, resulting in anemia. Treatments for MDS include erythropoiesis-stimulating agents (ESAs). The identification of prognostic markers is important to help predict response and improve outcomes. Various...

journal_title：Annals of hematology

authors： Park S,Kelaidi C,Meunier M,Casadevall N,Gerds AT,Platzbecker U

更新日期：2020-01-01 00:00:00

abstract：:We aimed to evaluate the treatments, particularly the role of corticosteroids, in patients with late-onset hemorrhagic cystitis (LOHC) after allogeneic hematopoietic stem cell transplantation (allo-HSCT). One hundred and sixty-three consecutive patients who underwent non-T-cell-depleted allo-HSCT and met the criterion...

journal_title：Annals of hematology

authors： Mo XD,Zhang XH,Xu LP,Wang Y,Yan CH,Chen H,Chen YH,Han W,Wang FR,Wang JZ,Liu KY,Huang XJ

更新日期：2018-07-01 00:00:00

abstract：:The main purpose of this report is to focus on the importance of an accurate etiologic diagnosis of gastrointestinal complications during chemotherapy for acute myeloid leukemia, taking into account that a syndrome characterized by bowel wall thickening associated with diarrhea and abdominal pain may have etiologies d...

journal_title：Annals of hematology

authors： Capria S,Vitolo D,Cartoni C,Dessanti L,Micozzi A,Mandelli F,Meloni G

更新日期：2004-03-01 00:00:00

abstract：:Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired hemolytic disease with thrombosis as a major complication. The mechanism of thrombosis and related risk factors in PNH patients are still not well characterized. We retrospectively enrolled 99 patients with newly diagnosed PNH at our institute from 2011 to 2016....

journal_title：Annals of hematology

authors： Huang Y,Liu X,Chen F,Zhou W,Li H,Long Z,Yang C,Chen M,Han B

更新日期：2019-10-01 00:00:00

abstract：:Although lenalidomide plus dexamethasone (RD) is a therapeutic option for relapsed/refractory multiple myeloma (RRMM), limited real-world clinical data exist. The purpose of this study was to estimate efficacy and safety of RD in RRMM patients of the clinical practice. Data from patients at 25 university hospitals in ...

journal_title：Annals of hematology

authors： Jo JC,Lee HS,Kim K,Lee JJ,Yoon SS,Bang SM,Kim JS,Eom HS,Yoon DH,Lee Y,Shin HJ,Park Y,Lee WS,Do YR,Mun YC,Lee MH,Kim HJ,Kim SH,Kim MK,Lim SN,Cho SH,Park SK,Yi JH,Lee JH,Kim J,Min CK,Korean Multiple Myel

更新日期：2020-02-01 00:00:00

abstract：:Reactive oxygen intermediates (ROI) generated in the respiratory burst reaction are crucial for the killing of bacteria and fungi in phagocytes. The key enzyme for the respiratory burst reaction is the NADPH oxidase. Reactive oxygen intermediates have additionally been proposed to be of general importance for the expr...

journal_title：Annals of hematology

authors： v Bernuth H,Kulka C,Roesler J,Gahr M,Rösen-Wolff A

更新日期：2004-04-01 00:00:00

abstract：:Autologous stem cell transplant (ASCT) is an effective treatment for non-Hodgkin lymphoma (NHL). However, recent supply issues and toxicity of carmustine have necessitated a new conditioning regimen. We conducted a multicenter, phase II study of BEB (busulfan, etoposide, and bendamustine) conditioning regimen for ASCT...

journal_title：Annals of hematology

authors： Kim DY,Chung JS,Jo JC,Cho SH,Shin HJ

更新日期：2020-04-01 00:00:00

abstract：:High-dose immunosuppressive therapy (HDIT) with autologous hematopoietic stem cell transplantation (AHSCT) is a promising approach to treatment of multiple sclerosis (MS) patients. In this paper, we present the long-term outcomes of a prospective single-center study with the analysis of the safety and efficacy of HDIT...

journal_title：Annals of hematology

authors： Shevchenko JL,Kuznetsov AN,Ionova TI,Melnichenko VY,Fedorenko DA,Kurbatova KA,Gorodokin GI,Novik AA

更新日期：2015-07-01 00:00:00

abstract：:B cell acute lymphoblastic leukemia (B-ALL) is an aggressive hematologic malignancy with limited treatment strategies. Histone deacetylases inhibitors (HDACis) are promising novel tools for cancer therapy, whose anti-tumor effects and the underlying mechanisms on B-ALL remain to be elucidated. Recently, Notch1 signali...

journal_title：Annals of hematology

authors： Shao N,Ma D,Wang J,Lu T,Guo Y,Ji C

更新日期：2013-01-01 00:00:00

abstract：:Only about one third of all patients with acute myeloid leukemia (AML) will be cured by common chemotherapy regimens. Susceptibility towards chemotherapy either of the leukemic bulk or the leukemic stem cell is considered the major determining parameter for long-term outcome. The purpose of the present study was to in...

journal_title：Annals of hematology

authors： Fiegl M,Zimmermann I,Lorenz I,Hiddemann W,Braess J

更新日期：2008-01-01 00:00:00

abstract：:Previous studies have suggested that adherence to imatinib therapy can be an obstacle among patients with chronic myeloid leukemia (CML). We studied adherence to imatinib therapy among CML patients treated at the Sahlgrenska University Hospital. We identified all CML patients that were alive at the 1st of January 2010...

journal_title：Annals of hematology

authors： Jönsson S,Olsson B,Söderberg J,Wadenvik H

更新日期：2012-05-01 00:00:00

abstract：:Thrombotic thrombocytopenic purpura (TTP) is a hematologic disorder which is clinically characterized by thrombocytopenia, microangiopathic hemolytic anemia, fever, neurologic symptoms, and cardiac and renal involvement. The pathogenic mechanisms of this disease are poorly understood. It is well known that TTP is asso...

journal_title：Annals of hematology

authors： Rozdzinski E,Hertenstein B,Schmeiser T,Seifried E,Kurrle E,Heimpel H

更新日期：1992-05-01 00:00:00

abstract：:Previous studies exploring associations between statin use and risk of multiple myeloma (MM) showed inconsistent results. We searched for articles published in English in databases (PubMed, Web of Science, EMBASE, Medline, and Google Scholar) before October 2019. The multivariate odds ratio (OR)/relative risk (RR) and...

journal_title：Annals of hematology

authors： Zhang P,Liu B

更新日期：2020-08-01 00:00:00

abstract：:We recently reported that IgM antibody-related microparticles exist in some patients with idiopathic thrombocytopenic purpura (ITP) [14]. In this study, we investigated the relationship between antiphospholipid (cardiolipin and phosphatidylinositol) antibodies and microparticles in 56 ITP patients. We used an ELISA to...

journal_title：Annals of hematology

authors： Nomura S,Yanabu M,Fukuroi T,Kido H,Kawakatsu T,Yamaguchi K,Suzuki M,Kokawa T,Yasunaga K

更新日期：1992-07-01 00:00:00

abstract：:Data are limited in developing countries regarding the clinicopathologic features and response to therapy of chronic myeloid leukemia (CML) in the era of imatinib (IM). The objective of this study is to report on the clinicoepidemiologic features of CML in Tunisia, to evaluate the long-term outcome of patients in chro...

journal_title：Annals of hematology

authors： Ben Lakhal R,Ghedira H,Bellaaj H,Ben Youssef Y,Menif S,Manai Z,Bedoui M,Lakhal A,M'Sadek F,Elloumi M,Khélif A,Ben Romdhane N,Laatiri MA,Ben Othmen T,Meddeb B

更新日期：2018-04-01 00:00:00

abstract：:Controversy remains regarding the transplant outcomes of human leukocyte antigen-identical related bone marrow transplantation (BMT) and peripheral blood stem cell transplantation (PBSCT) for the treatment of patients with hematological malignancies. To provide an estimate of the effect of BMT and PBSCT on clinical ou...

journal_title：Annals of hematology

authors： Chang YJ,Weng CL,Sun LX,Zhao YT

更新日期：2012-03-01 00:00:00

abstract：:Venous thromboembolism (VTE) is a well-recognized complication in pediatric oncology patients. Studies in adult oncology patients have suggested a potential negative association between VTE and survival, but this association has not been examined in pediatric patients yet. The aim of this study was to assess the assoc...

journal_title：Annals of hematology

authors： Forbrigger Z,Kuhle S,Brown MM,Moorehead PC,Digout C,Kulkarni K

更新日期：2018-10-01 00:00:00

abstract：:Second allogeneic hematopoietic stem cell transplantation (allo-HSCT) has a low survival outcome and a high non-relapse mortality (NRM) rate which is a major obstacle to this treatment. We hypothesized that the status of malnourishment after first allo-HSCT as represented by the geriatric nutritional risk index (GNRI)...

journal_title：Annals of hematology

authors： Kaito S,Wada A,Adachi H,Konuma R,Kishida Y,Nagata A,Konishi T,Yamada Y,Kumagai T,Yoshifuji K,Mukae J,Akiyama M,Inamoto K,Toya T,Igarashi A,Najima Y,Muto H,Kobayashi T,Kakihana K,Ohashi K,Sakamaki H,Doki N

更新日期：2020-07-01 00:00:00

abstract：:Diagnosis of thrombotic thrombocytopenic purpura (TTP) is usually based upon the clinical features, and does not always involve histopathological evidence. We recently had experience with a patient who developed the five signs characteristic for TTP. He had been treated for liver cirrhosis associated with chronic hepa...

journal_title：Annals of hematology

authors： Hori A,Kami M,Hamaki T,Yamamoto T,Mori M,Miyakoshi S,Takeuchi K

更新日期：2001-08-01 00:00:00

abstract：:Chronic hepatitis C (CHC) and iron overload are the main causes of liver disease in β-thalassemia major (βTM). There is limited data regarding the course of CHC in this population. All patients (n=144) from the thalassemia centre of the University Hospital of Patras were evaluated (January 1981 to June 2012). Patients...

journal_title：Annals of hematology

authors： Triantos C,Kourakli A,Kalafateli M,Giannakopoulou D,Koukias N,Thomopoulos K,Lampropoulou P,Bartzavali C,Fragopanagou H,Kagadis GC,Christofidou M,Tsamandas A,Nikolopoulou V,Karakantza M,Labropoulou-Karatza C

更新日期：2013-06-01 00:00:00

abstract：:Cytomegalovirus (CMV) can cause end-organ diseases including pneumonia, gastroenteritis, retinitis, and encephalitis in hematopoietic stem cell transplantation recipients. Potential differences among different CMV diseases remain uncertain. This study aimed to compare the clinical characteristics, risk factors, and mo...

journal_title：Annals of hematology

authors： Meng XY,Fu HX,Zhu XL,Wang JZ,Liu X,Yan CH,Zhang YY,Mo XD,Wang Y,Han W,Chen YH,Chen DB,Liu HX,Chang YJ,Xu LP,Liu KY,Huang XJ,Zhang XH

更新日期：2020-11-01 00:00:00

abstract：:Most cases of erythrocytosis occur secondary to chronic tissue hypoxia or as a clonal disease such as polycythemia vera with somatic mutations in the Janus kinase 2 (JAK2) gene. Rarely, erythrocytosis is caused by hereditary gene mutations. This study investigated hereditary gene mutations in 38 unrelated Korean patie...

journal_title：Annals of hematology

authors： Jang JH,Seo JY,Jang J,Jung CW,Lee KO,Kim SH,Kim HJ

更新日期：2014-06-01 00:00:00

abstract：:The appropriate management of patients with moderate aplastic anemia (mAA) remains to be unclear and controversial. A cohort of 118 patients with mAA received a novel immunosuppressive strategy of cyclosporine alternately combined with levamisole (CSA and LMS regimen), which included 42 newly diagnosed and 76 chronic ...

journal_title：Annals of hematology

authors： Li X,Shao Y,Ge M,Shi J,Huang J,Huang Z,Zhang J,Nie N,Zheng Y

更新日期：2013-09-01 00:00:00

abstract：:Spontaneous splenic rupture is a rare, though life-threatening complication of some hematological malignancies and is even more infrequent as the initial symptom of acute lymphoblastic leukemia. We describe the fourth case, to our knowledge, of acute lymphoblastic leukemia presenting as splenic rupture, and for the fi...

journal_title：Annals of hematology

authors： Altès A,Brunet S,Martinez C,Soler J,Ayats R,Sureda A,López R,Domingo A

更新日期：1994-03-01 00:00:00

abstract：:The patient was initially diagnosed as having non-Hodgkin's lymphoma and was cured following treatment with prednisolone, vincristine, daunorubicin, 1-asparaginase, and cyclophosphamide. Seven years and two months later, he developed osteosarcoma in his right femur. He received chemotherapy consisting of methotrexate,...

journal_title：Annals of hematology

authors： Kubota M,Sawada M,Watanabe K,Koishi S,Kataoka A,Usami I,Lin YW,Okuda A,Akiyama Y,Furusho K

更新日期：1997-02-01 00:00:00

abstract：:We discuss possible justifications to split study populations from a biometrical point of view. The existence of prognostic differences between subgroups are neither a sufficient nor a necessary reason to justify a splitting decision. There are essentially two separate types of relevant arguments to justify a split of...

journal_title：Annals of hematology

authors： Hasenclever D,Loeffler M

更新日期：2001-01-01 00:00:00

abstract：:To determine the value of aerosol amphotericin B inhalations for prevention of invasive pulmonary aspergillosis (IPA), we initiated a prospective randomized multicenter trial. The scheduled intent-to-treat interim analysis included 115 patients (30%) with prolonged neutropenia after chemotherapy for acute myeloid leuk...

journal_title：Annals of hematology

authors： Behre GF,Schwartz S,Lenz K,Ludwig WD,Wandt H,Schilling E,Heinemann V,Link H,Trittin A,Boenisch O

更新日期：1995-12-01 00:00:00