Successful alemtuzumab retreatment in progressive B-cell chronic lymphocytic leukemia: a multicenter survey in 30 patients.

abstract：:A case of an 82-year-old man who suffered an acute ST-elevation myocardial infarction while receiving treatment with intravenous immunoglobulin (IVIg) for thrombocytopenia is discussed. A total of 29 other cases of thromboembolism related to IVIg therapy have been reported, and the incidence seems to be especially hig...

journal_title：Annals of hematology

authors： Hefer D,Jaloudi M

更新日期：2004-10-01 00:00:00

abstract：:In this report we show that serum has differentiation-inducing effects on primitive hematopoietic progenitor cells with the CD34++CD38- immunophenotype. Using the pre-colony forming unit (pre-CFU) assay as a model for early myelopoiesis, we compared the effects of serum-containing and serum-free media and evaluated di...

journal_title：Annals of hematology

authors： Willems R,Henckaerts E,Lenjou M,Nijs G,Rodrigus I,Moulijn AC,Slegers H,Berneman ZN,Van Bockstaele DR

更新日期：2001-01-01 00:00:00

abstract：:Data on clinical features and outcome in pediatric follicular lymphoma (pFL) are scarce. The aim of this retrospective study including 13 EICNHL and/or i-BFM study group members was to assess clinical characteristics and course in a series of 63 pFL patients. pFL was found to be associated with male gender (3:1), olde...

journal_title：Annals of hematology

authors： Attarbaschi A,Beishuizen A,Mann G,Rosolen A,Mori T,Uyttebroeck A,Niggli F,Csoka M,Krenova Z,Mellgren K,Kabickova E,Chiang AK,Reiter A,Williams D,Burkhardt B,European Intergroup for Childhood Non-Hodgkin Lymphoma (EICNHL) an

更新日期：2013-11-01 00:00:00

abstract：:Recently, the combination of rituximab and bendamustine (R-Benda) has been defined as highly active in patients with follicular lymphomas, but little is known about the efficacy of R-Benda in mucosa-associated lymphoid tissue (MALT) lymphoma. In a retrospective analysis, we have defined 14 patients with MALT lymphoma ...

journal_title：Annals of hematology

authors： Kiesewetter B,Mayerhoefer ME,Lukas J,Zielinski CC,Müllauer L,Raderer M

更新日期：2014-02-01 00:00:00

abstract：:Cells of the macrophage lineage are a major source of various cytokines and hematopoietic growth factors. With regard to the growth factors acting on cells of their own lineage, macrophage colony-stimulating factor (M-CSF) has been proven to be secreted by monocytes (MO) and macrophages (MAC), whereas the production o...

journal_title：Annals of hematology

authors： Krause SW,Kreutz M,Zenke G,Andreesen R

更新日期：1992-04-01 00:00:00

abstract：:Activation-induced cytidine deaminase (AID) is a mutator enzyme essential for somatic hypermutation (SHM) and class switch recombination (CSR) during effective adaptive immune responses. Its aberrant expression and activity have been detected in lymphomas, leukemias, and solid tumors. In chronic lymphocytic leukemia (...

journal_title：Annals of hematology

authors： Zaprazna K,Reblova K,Svobodova V,Radova L,Bystry V,Baloun J,Durechova K,Tom N,Loja T,Buresova M,Stranska K,Oltova A,Doubek M,Atchison ML,Trbusek M,Malcikova J,Pospisilova S

更新日期：2019-02-01 00:00:00

abstract：PURPOSE AND METHODS:Nowadays more people are becoming older. The median age of a patient with non-Hodgkin's lymphoma (NHL) at diagnosis is over 60 years. The incidence of NHL in elderly has increased in the last decades. Therefore, in the future, NHL will be diagnosed more often in the elderly. Data of all patients in ...

journal_title：Annals of hematology

authors： Peters FP,Lalisang RI,Fickers MM,Erdkamp FL,Wils JA,Houben SG,Wals J,Schouten HC

更新日期：2001-03-01 00:00:00

abstract：:The introduction of rituximab into the primary treatment of malignant lymphomas of the B cell lineage has had a major impact on the management of these diseases. In addition, prolonged exposure to rituximab as maintenance therapy has been beneficial in patients with follicular lymphoma and mantle cell lymphoma. For th...

journal_title：Annals of hematology

authors： Witzens-Harig M,Reiz M,Heiss C,Benner A,Hensel M,Neben K,Dreger P,Kraemer A,Ho AD

更新日期：2009-01-01 00:00:00

abstract：:Since July 2017, different generic imatinib formulations have been introduced in Italy for the treatment of patients with chronic myeloid leukemia (CML). We analyzed 168 chronic phase CML patients treated with branded imatinib for a median of 12 years (range 1-16) at a single institution who switched to a single gener...

journal_title：Annals of hematology

authors： Scalzulli E,Colafigli G,Latagliata R,Pepe S,Diverio D,Stocchi F,Di Prima A,Efficace F,Martelli M,Foà R,Breccia M

更新日期：2020-12-01 00:00:00

abstract：:The role of 18FDG-PET/CT during follow-up of patients affected by Hodgkin's lymphoma (HL) in complete remission after treatment is not fully elucidated, since a wide use of 18F fluorodeoxyglucose positron emission tomography/computed tomography (18FDG-PET/CT) in this setting could be limited by a relative high rate of...

journal_title：Annals of hematology

authors： Crocchiolo R,Fallanca F,Giovacchini G,Ferreri AJ,Assanelli A,Verona C,Pescarollo A,Bregni M,Ponzoni M,Gianolli L,Fazio F,Ciceri F

更新日期：2009-12-01 00:00:00

abstract：:Chronic hepatitis C (CHC) and iron overload are the main causes of liver disease in β-thalassemia major (βTM). There is limited data regarding the course of CHC in this population. All patients (n=144) from the thalassemia centre of the University Hospital of Patras were evaluated (January 1981 to June 2012). Patients...

journal_title：Annals of hematology

authors： Triantos C,Kourakli A,Kalafateli M,Giannakopoulou D,Koukias N,Thomopoulos K,Lampropoulou P,Bartzavali C,Fragopanagou H,Kagadis GC,Christofidou M,Tsamandas A,Nikolopoulou V,Karakantza M,Labropoulou-Karatza C

更新日期：2013-06-01 00:00:00

abstract：:We have established reference values of peripheral blood lymphocyte subsets in healthy female Wistar rats under highly standardized conditions. Using monoclonal antibodies and flow cytometry, T lymphocytes (OX19+), B lymphocytes (OX6+ and anti-Ig+), T-helper/inducer (W3/25+), and T-suppressor/cytotoxic subsets (OX8+) ...

journal_title：Annals of hematology

authors： Franch A,Castellote C,Pelegrí C,Tolosa E,Castell M

更新日期：1993-09-01 00:00:00

abstract：:The general impact of blood donation on iron status was studied in a population survey comprising 1359 nonpregnant Danish women in age cohorts of 30, 40, 50, and 60 years; 809 were premenopausal and 550 postmenopausal; 180 (13%) were blood donors. Iron stores were assessed by serum (S)-ferritin and hemoglobin (Hb). Hb...

journal_title：Annals of hematology

authors： Milman N,Kirchhoff M

更新日期：1991-07-01 00:00:00

abstract：:Mixed phenotype acute leukemia (MPAL) is a rare type of leukemia with a limited number of studies conducted to characterize its clinical spectrum and most importantly the best treatment modality. MPAL blasts show more than one phenotype either myeloid/monocytic with T- or B-lymphoid or extremely rare triple lineage as...

journal_title：Annals of hematology

authors： Rasekh EO,Osman R,Ibraheem D,Madney Y,Radwan E,Gameel A,Abdelhafiz A,Kamel A,Elfishawi S

更新日期：2020-11-23 00:00:00

abstract：:Ninety patients with Philadelphia chromosome-positive chronic myelogenous leukemia in blast crisis were reviewed to identify significant prognostic associations. At diagnosis of blast crisis the main clinical, laboratory, and cytogenetic data were recorded and evaluated for prognostic significance. At the time of the ...

journal_title：Annals of hematology

authors： Griesshammer M,Heinze B,Hellmann A,Popp C,Anger B,Heil G,Bangerter M,Heimpel H

更新日期：1996-11-01 00:00:00

abstract：:Only about one third of all patients with acute myeloid leukemia (AML) will be cured by common chemotherapy regimens. Susceptibility towards chemotherapy either of the leukemic bulk or the leukemic stem cell is considered the major determining parameter for long-term outcome. The purpose of the present study was to in...

journal_title：Annals of hematology

authors： Fiegl M,Zimmermann I,Lorenz I,Hiddemann W,Braess J

更新日期：2008-01-01 00:00:00

abstract：:Organizing pneumonia (OP) is a poorly understood complication of hematopoietic stem cell transplant (HSCT). We identified 15 patients diagnosed with OP following HSCT and described their clinical course. CT chest findings were remarkable for multifocal infiltrates that were predominantly consolidating or ground glass ...

journal_title：Annals of hematology

authors： Brownback KR,Frey JW,Abhyankar S

更新日期：2019-09-01 00:00:00

abstract：:Secondary hemophagocytic lymphohistiocytosis (HLH) is a rare but fatal condition with various underlying disorders in adult patients and is diagnosed based on the HLH-2004 criteria, which were established based on experience in pediatric patients. However, few studies have prospectively evaluated the treatment outcome...

journal_title：Annals of hematology

authors： Yoon SE,Eun Y,Huh K,Chung CR,Yoo IY,Cho J,Cho D,Ko YH,Park S,Kim WS,Kim SJ

更新日期：2020-09-01 00:00:00

abstract：:Relapse remains one of the major obstacles in Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL) even after allogeneic hematopoietic stem cell transplantation. The persistence of leukemia-propagating cells (LPCs) may lead to the recurrence of Ph+ALL. Using a xenograft assay, LPCs enrichment in the ...

journal_title：Annals of hematology

authors： Zhao HY,Song Y,Cao XN,Qin YZ,Lai YY,Jiang H,Jiang Q,Huang XJ,Kong Y

更新日期：2018-05-01 00:00:00

abstract：:The prognostic impact of extramedullary plasmacytomas (EMPs) on newly diagnosed symptomatic multiple myeloma (MM) was evaluated in the context of treatment approach including autologous stem cell transplantation (ASCT) and chemotherapy alone. A total of 275 consecutive patients with newly diagnosed MM were included, a...

journal_title：Annals of hematology

authors： Lee SE,Kim JH,Jeon YW,Yoon JH,Shin SH,Eom KS,Kim YJ,Kim HJ,Lee S,Cho SG,Lee JW,Min WS,Park CW,Min CK

更新日期：2015-03-01 00:00:00

abstract：:Previous studies exploring associations between statin use and risk of multiple myeloma (MM) showed inconsistent results. We searched for articles published in English in databases (PubMed, Web of Science, EMBASE, Medline, and Google Scholar) before October 2019. The multivariate odds ratio (OR)/relative risk (RR) and...

journal_title：Annals of hematology

authors： Zhang P,Liu B

更新日期：2020-08-01 00:00:00

abstract：:In the present study, we questioned whether the cholesterol synthesis inhibitor lovastatin potentiates the cytotoxicity of chemotherapeutic agents in the primitive CD34(+) subpopulation of acute myeloid leukemia (AML) cells. AML mononuclear cells (n = 17) were sorted in CD34(+) and CD34(-) fractions and compared to no...

journal_title：Annals of hematology

authors： de Jonge-Peeters SD,van der Weide K,Kuipers F,Sluiter WJ,de Vries EG,Vellenga E

更新日期：2009-06-01 00:00:00

abstract：:To investigate the problem of allogeneic bone marrow transplantation (allo-BMT) for advanced stage patients, we retrospectively analyzed 24 consecutive patients who underwent allo-BMT in the non-remission stage. Twenty-four patients (19 males and 5 females) with acute leukemia, chronic myelogenous leukemia, and malign...

journal_title：Annals of hematology

authors： Tabata M,Satake A,Okura N,Yamazaki Y,Toda A,Nishioka K,Tanaka H,Chin M,Itsukuma T,Yamaguchi M,Misawa M,Kai S,Hara H

更新日期：2002-10-01 00:00:00

abstract：:Recommendations for dyslipidemia management aimed at reducing arterial occlusive events (AOEs) have been recently published. So far, no data have been reported on the management of dyslipidemia in chronic myeloid leukemia (CML) patients treated with nilotinib. We investigated 369 CML adult patients, stratified accordi...

journal_title：Annals of hematology

authors： Caocci G,Mulas O,Capodanno I,Bonifacio M,Annunziata M,Galimberti S,Luciano L,Tiribelli M,Martino B,Castagnetti F,Binotto G,Pregno P,Stagno F,Abruzzese E,Bocchia M,Gozzini A,Albano F,Fozza C,Luzi D,Efficace F,Simul

更新日期：2021-01-03 00:00:00

abstract：:Evaluation of bone marrow involvement (BMI) by conventional bone marrow biopsy (BMB) can generate false-negative results if marrow disease is focal. The sensitivity of 18F-2-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (FDG-PET/CT) in assessing BMI in extranodal NK/T cell lymphoma (ENKL) h...

journal_title：Annals of hematology

authors： Zhou Z,Chen C,Li X,Li Z,Zhang X,Chang Y,Lu L,Cui Y,Ma Y,Zhang M

更新日期：2015-06-01 00:00:00

abstract：:Ruxolitinib, a JAK1 and JAK2 inhibitor, has been tested and approved for the treatment of primary and secondary myelofibrosis (MF). Aim of our study is to report safety and efficacy of ruxolitinib in 98 patients affected by MF treated outside clinical trials and collected and treated consecutively by the Lazio Coopera...

journal_title：Annals of hematology

authors： Breccia M,Andriani A,Montanaro M,Abruzzese E,Buccisano F,Cedrone M,Centra A,Villivà N,Celesti F,Trawinska MM,Massaro F,Di Veroli A,Anaclerico B,Colafigli G,Molica M,Spadea A,Petriccione L,Cimino G,Latagliata R

更新日期：2017-03-01 00:00:00

abstract：:A 4-day colorimetric tetrazolium dye (MTT) assay was used to assess the cytotoxicity of adriamycin (ADM), vincristine (VCR), and idarubicin (IDA) in blasts isolated from 37 patients with newly diagnosed and pretreated acute myeloid leukemia (AML). The effect of verapamil (VRP) as a chemosensitizer was studied in relat...

journal_title：Annals of hematology

authors： Müller MR,Lennartz K,Boogen C,Nowrousian MR,Rajewsky MF,Seeber S

更新日期：1992-11-01 00:00:00

abstract：:In vivo, growth factors are currently investigated for their capacity to trigger leukemic stem cells into cycle and thus overcome kinetic drug resistance. In this study, the susceptibility of leukemic clonogenic cells to individual growth factors was related to cytosine-arabinoside (Ara-C) sensitivity. The effects of ...

journal_title：Annals of hematology

authors： Van der Lely N,De Witte T,Wessels J,Raymakers R,Muus P,Preijers F

更新日期：1994-05-01 00:00:00

abstract：:The objective of this study was to evaluate retrospectively the clinical characteristics, treatments, and outcomes of patients with primary diffuse large B-cell lymphoma (DLBCL) of the female genital tract. The basic characteristics, treatments, and outcomes of six patients diagnosed with primary DLBCL of the female g...

journal_title：Annals of hematology

authors： Cao XX,Li J,Zhang W,Duan MH,Shen T,Zhou DB

更新日期：2014-06-01 00:00:00

abstract：:Allogeneic hematopoietic cell transplantation (allo-HCT) remains the only curative treatment option for myelofibrosis (MF) despite the emergence of novel targeted therapies. To reduce graft rejection and graft-versus-host disease (GvHD), current allo-HCT protocols often include in vivo T lymphocyte depletion using pol...

journal_title：Annals of hematology

authors： Ecsedi M,Schmohl J,Zeiser R,Drexler B,Halter J,Medinger M,Duyster J,Kanz L,Passweg J,Finke J,Bethge W,Lengerke C

更新日期：2016-10-01 00:00:00