Cortical evoked responses following esophageal balloon distension and electrical stimulation in healthy volunteers.

abstract：:Both intracellular calcium ions and neural input are important in esophageal smooth muscle contraction. The aim of this study was to compare the effects of well-tolerated doses of the calcium-channel blocker, nifedipine (20 mg sublingually/buccally) with the anticholinergic, propantheline bromide (15 mg orally) and th...

journal_title：Digestive diseases and sciences

authors： Hongo M,Traube M,McCallum RW

更新日期：1984-04-01 00:00:00

abstract：:Metronidazole has been used to treat pouchitis, but there are no controlled data that show it is effective. Chronic unremitting pouchitis is a form of the disorder particularly difficult to manage. Diarrhea is the main symptom of pouchitis, which results from acute inflammation of the mucosa of an ileal reservoir. To ...

journal_title：Digestive diseases and sciences

authors： Madden MV,McIntyre AS,Nicholls RJ

更新日期：1994-06-01 00:00:00

abstract：:The presence in the esophagus of three distinct entities--Barrett's mucosa, Crohn's disease, and adenocarcinoma--is a very rare finding. In a 60-year-old man with a long history of heartburn and recently developed dysphagia, narrowing of the distal esophagus was found to be related to the presence of Barrett's mucosa....

journal_title：Digestive diseases and sciences

authors： Delpre G,Mor C,Avidor I,Gutman H,Leisser A,Kott I,Kadish U

更新日期：1989-02-01 00:00:00

abstract：:The diagnosis of irritable bowel syndrome requires the exclusion of any associated organic disease: a positive diagnosis would avoid expensive and potentially dangerous diagnostic procedures. A scoring system has been proposed for positive diagnosis where more than 44 points excluded organic digestive disease. The aim...

journal_title：Digestive diseases and sciences

authors： Frigerio G,Beretta A,Orsenigo G,Tadeo G,Imperiali G,Minoli G

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Obesity is a known risk factor for diverticulitis. Our objective was to examine the less investigated impact of morbid obesity (MO) on admissions and clinical course of diverticulitis in a US representative database. METHODS:We retrospectively queried the 2010-2014 Nationwide Readmission Database t...

journal_title：Digestive diseases and sciences

authors： Patel K,Krishna SG,Porter K,Stanich PP,Mumtaz K,Conwell DL,Clinton SK,Hussan H

更新日期：2020-09-01 00:00:00

abstract：:An intussusception of the small intestine in association with a long tube usually occurs in the vicinity of the mercury-filled bag and can be visualized radiographically by instilling barium directly into the tube. On rare occasions, an intussusception develops in the proximal jejunum and is difficult to recognize. We...

journal_title：Digestive diseases and sciences

authors： Peskin SR,Langevin RE Jr,Banks PA

更新日期：1986-06-01 00:00:00

abstract：:The effect of chemical deafferentation, vagotomy (VGX), and gangliosympathectomy (GSX) on the density of fibers containing calcitonin gene-related peptide (CGRP) and substance P (Sub.P) in the rat gastric wall was studied. Chemical deafferentation by capsaicin abolished the density of CGRP-immunoreactive (IR) fibers, ...

journal_title：Digestive diseases and sciences

authors： Suzuki T,Kagoshima M,Shibata M,Inaba N,Onodera S,Yamaura T,Shimada H

更新日期：1997-06-01 00:00:00

abstract：:Sera from Japanese patients with chronic liver disease were tested for hepatitis B virus (HBV) markers and antibodies to hepatitis C virus (anti-HCV), and the results were correlated to the presence of hepatocellular carcinoma. In chronic non-A, non-B liver disease, anti-HCV prevalence was high both in patients with h...

journal_title：Digestive diseases and sciences

authors： Yuki N,Hayashi N,Kasahara A,Hagiwara H,Katayama K,Fusamoto H,Kamada T

更新日期：1992-01-01 00:00:00

abstract：:Inhibition of monoamine oxidase B (MAO B) by selective inhibitors pargyline and L-deprenyl increases dopamine (DA) and norepinephrine (NE) concentrations in nucleus accumbens (NACB) and is associated with reduction in cold water restraint-induced gastric mucosal injury, inhibition of basal gastric acid output, and reg...

journal_title：Digestive diseases and sciences

authors： Xing LP,Washington J,Seaton J,Kauffman G Jr

更新日期：1990-01-01 00:00:00

abstract：:The efficacy of comaruman CP, a pectin of marsh cinquefoil Comarum palustre L., was investigated using a model of acetic acid-induced colitis in mice. Mice were administered comaruman CP orally 2 days prior to rectal injection of 5% acetic acid and examined for colonic damage 24 hr later. Colonic inflammation was char...

journal_title：Digestive diseases and sciences

authors： Popov SV,Ovodova RG,Markov PA,Nikitina IR,Ovodov YS

更新日期：2006-09-01 00:00:00

abstract：:Peutz-Jeghers syndrome (PJS) is an autosomal-dominant inherited disorder characterized by mucocutaneous pigmentation, hamartomatous polyposis of the gastrointestinal tract, and an increased risk for the development of both gastrointestinal and extraintestinal malignancies. Germline mutation of the STK11 gene, which en...

journal_title：Digestive diseases and sciences

authors： Gao Y,Zhang FM,Huang S,Wang X,Zhang P,Huang XD,Ji GZ,Fan ZN

更新日期：2010-04-01 00:00:00

abstract：:The effect of luminal 150 mmol saline, 0.05-0.2% (w/v) lysolecithin, and 5-20% (v/v) ethanol was studied on the mucosal morphology of the proximal small intestine in conscious guinea pigs as well as on the mucosal penetration and transfer to portal venous blood of luminal horseradish peroxidase (HRP). No ultrastructur...

journal_title：Digestive diseases and sciences

authors： Talbot RW,Foster JR,Hermon-Taylor J,Grant DA

更新日期：1984-11-01 00:00:00

abstract：OBJECTIVE:The regulation of apoptosis of intestinal mucosal cells is important in maintenance of normal intestinal physiology. SUMMARY:Sphingosine-1-phosphate (S1P) has been shown to play a critical role in cellular protection to otherwise lethal stimuli in several nonintestinal tissues. METHODS:The current study det...

journal_title：Digestive diseases and sciences

authors： Greenspon J,Li R,Xiao L,Rao JN,Marasa BS,Strauch ED,Wang JY,Turner DJ

更新日期：2009-03-01 00:00:00

abstract：:Angiotensin II (Ang II) has been reported to promote tumor progression, tumor growth and angiogenesis in many cancers. We previously observed that angiotensin II type 1 receptors (AT1R) were upregulated in human gastric cancer and may be involved in the progression of gastric cancer. We studied the effects of AT1R ant...

journal_title：Digestive diseases and sciences

authors： Huang W,Wu YL,Zhong J,Jiang FX,Tian XL,Yu LF

更新日期：2008-05-01 00:00:00

abstract：:Colonoscopy is the dominant colorectal cancer screening strategy in the USA. There are no randomized controlled trials completed of screening colonoscopy, but multiple lines of evidence establish that colonoscopy reduces colorectal cancer incidence in both the proximal and distal colon. Colonoscopy is highly operator ...

journal_title：Digestive diseases and sciences

authors： Rex DK

更新日期：2015-03-01 00:00:00

abstract：:The major heat shock protein, HSP70, is known to be involved in cytoprotection against environmental stresses mediated by their function as a "molecular chaperone." However, the influence of HSP70 on gastric mucosal healing under physical stimulation or stress is not completely understood. Rat gastric mucosal cells (R...

journal_title：Digestive diseases and sciences

authors： Odashima M,Otaka M,Matsuhashi T,Jin M,Horikawa Y,Ohba R,Itoh H,Watanabe S

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Restoring normal fecal flora through intestinal microbiota transplantation (IMT) was successful in curing recurrent Clostridium difficile infection (CDI). However, only a few cases have been reported of IMT being utilized for the treatment of severe or fulminant CDI. AIM:Is IMT a simple and effective treatm...

journal_title：Digestive diseases and sciences

authors： Zainah H,Hassan M,Shiekh-Sroujieh L,Hassan S,Alangaden G,Ramesh M

更新日期：2015-01-01 00:00:00

abstract：INTRODUCTION:Natural language processing is a powerful technique of machine learning capable of maximizing data extraction from complex electronic medical records. METHODS:We utilized this technique to develop algorithms capable of "reading" full-text radiology reports to accurately identify the presence of fatty live...

journal_title：Digestive diseases and sciences

authors： Redman JS,Natarajan Y,Hou JK,Wang J,Hanif M,Feng H,Kramer JR,Desiderio R,Xu H,El-Serag HB,Kanwal F

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Data on cyclic vomiting syndrome (CVS) are limited to studies from tertiary care centers. There is a paucity of information about CVS on a national scale. AIM:To study the clinical characteristics, comorbidities, and hospital outcomes in patients hospitalized with CVS using a nationwide database. METHODS:W...

journal_title：Digestive diseases and sciences

authors： Bhandari S,Venkatesan T

更新日期：2017-08-01 00:00:00

abstract：:Despite many studies on pain of functional gastrointestinal disorders (FGID), the pain mechanism of FGID is not well understood, and pain treatment of FGID is not established. Following our former functional dyspepsia (FD) study, we proposed two subgroups of patients with irritable bowel syndrome (IBS), pain and disco...

journal_title：Digestive diseases and sciences

authors： Handa M,Nukina H,Ando K,Kubo C

更新日期：2004-04-01 00:00:00

abstract：AIM:Renal toxicity of adefovir disoproxil (ADV) and tenofovir disoproxil fumarate (TDF) is a significant concern in chronic hepatitis B (CHB) patients. Early observational clinical data suggested that telbivudine (LdT) might have renoprotective effects. METHODS:In this prospective study, consecutive CHB patients on co...

journal_title：Digestive diseases and sciences

authors： Mak LY,Liu SH,Yap DY,Seto WK,Wong DK,Fung J,Chan TM,Lai CL,Yuen MF

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Prior to the consensus guideline conference in 2007, eosinophilic esophagitis (EoE) was uncommon dominated by the fibrostenotic phenotype, but over the past decade has become a common cause of dysphagia with more inflammatory phenotypes diagnosed. We assessed the impact of guideline definitions on t...

journal_title：Digestive diseases and sciences

authors： Lipka S,Boyce HW,Kumar A,Richter JE

更新日期：2015-06-01 00:00:00

abstract：:Among 56 cases who presented to Kanto-Teishin Hospital complaining of bloody diarrhea or considerable hematochezia of acute onset, 8 cases (14.3%) were considered due to colitis associated with oral ampicillin therapy. The bloody diarrhea, often with abdominal cramps, began 2-7 days after starting the treatment. The d...

journal_title：Digestive diseases and sciences

authors： Sakurai Y,Tsuchiya H,Ikegami F,Funatomi T,Takasu S,Uchikoshi T

更新日期：1979-12-01 00:00:00

abstract：BACKGROUND:Globus sensation is common, but its pathogenesis is not yet clear. AIMS:Our purpose was to investigate subjective perception of swallowing and esophageal motility by combined multichannel intraluminal impedance and manometry (MII-EM) for patients with globus sensation. METHODS:Combined MII-EM was performed...

journal_title：Digestive diseases and sciences

authors： Chen CL,Yi CH,Liu TT

更新日期：2013-04-01 00:00:00

abstract：:Previous studies showed that bile salts had a promoting effect on colon cancer development and this effect was inhibited by ursodeoxycholate (UDC). We recently found that both human colorectal adenomas and carcinomas were associated with a specific decrease in alkaline sphingomyelinase activity. In this work, we compa...

journal_title：Digestive diseases and sciences

authors： Duan RD,Cheng Y,Tauschel HD,Nilsson A

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Topical pharyngeal anesthesia as an adjunct to intravenous sedation to facilitate gastroscopy has been widely acknowledged; however, its efficacy has not been established when it is used in patients under deep sedation with propofol. AIMS:To demonstrate the limited value of topical pharyngeal anesthesia in ...

journal_title：Digestive diseases and sciences

authors： Tsai HI,Tsai YF,Liou SC,Su MY,Lin CC,Chang CJ,Yu HP

更新日期：2012-10-01 00:00:00

abstract：:The efficacy of short-course (three months), low-dose (3 million units three times a week) interferon as treatment for acute hepatitis C was evaluated in a meta-analysis of controlled trials. Nine studies (five randomized and four nonrandomized) found by MEDLINE search were eligible for analysis. The outcomes assessed...

journal_title：Digestive diseases and sciences

authors： Cammà C,Almasio P,Craxì A

更新日期：1996-06-01 00:00:00

abstract：BACKGROUND:Prior studies have shown poor compliance with quality measures for IBD at academic and private practices. We sought to provide focused interventions to improve compliance and documentation with the IBD measures. METHODS:Two centers, academic practice (AP) and private practice (PP), initially reviewed their ...

journal_title：Digestive diseases and sciences

authors： Feuerstein JD,Papamichael K,Popejoy S,Nadelson A,Lewandowski JJ,Geissler K,Martinez-Vazquez M,Leffler DA,Ariyabuddhiphongs K,Thukral C,Cheifetz AS

更新日期：2018-01-01 00:00:00

abstract：:The intestine-specific caudal-related homeobox transcription factor Cdx2 is widely accepted to play a key role in intestinal development and differentiation in mammals. We studied the role of Cdx2 in the development of Barrett's esophagus (BE). In previous studies, we have shown a sequence of morphological changes of ...

journal_title：Digestive diseases and sciences

authors： Tatsuta T,Mukaisho K,Sugihara H,Miwa K,Tani T,Hattori T

更新日期：2005-03-01 00:00:00

abstract：:In conscious dogs with gastric and duodenal Thomas fistulas, we studied the effect of ethanol on plasma concentrations of gastrin. Ethanol was given either as an infusion into a peripheral vein (1.95 M, 200 ml/hr) or into the duodenum (0.95 M, 400 ml/hr) or as an intragastric bolus injection. The effect of the intraga...

journal_title：Digestive diseases and sciences

authors： Eysselein VE,Singer MV,Wentz H,Goebell H

更新日期：1984-01-01 00:00:00