Regulation of the 11 beta-hydroxysteroid dehydrogenase in the rat adrenal. Decrease enzymatic activity induced by ACTH.

abstract：:In order to determine the profiles and sources of inhibin A and inhibin B during pregnancy in Japanese monkeys, serum samples were collected from eight monkeys for measuring concentrations of both inhibins by enzyme-linked immunosorbent assay. The term placenta was used for the localization of inhibin alpha-, betaA-, ...

journal_title：Endocrine

authors： Kojima C,Kondo M,Jin W,Shimizu K,Itoh M,Watanabe G,Groome NP,Taya K

更新日期：2002-06-01 00:00:00

abstract：:In order to identify GH target cells in human tissues, we investigated the celiuiar distribution of human GH receptor (GHR) messenger RNA. This was performed byin situ hybridization and Northern blot hybridization using complementary radioactive DNA probe encoding part of the extracellular domain of the GHR. Several t...

journal_title：Endocrine

authors： Mertani HC,Delehaye-Zervas MC,Martini JF,Postel-Vinay MC,Morel G

更新日期：1995-02-01 00:00:00

abstract：:It is well known that TSH plays a major role in the secretion of thyroid hormones, maintenance of thyroid specific gene expression, and gland growth. In this study, we aimed to evaluate association between tests of thyroid functions (fT3, fT4, TSH) and differentiated thyroid carcinoma. 441 patients operated for nodula...

journal_title：Endocrine

authors： Gul K,Ozdemir D,Dirikoc A,Oguz A,Tuzun D,Baser H,Ersoy R,Cakir B

更新日期：2010-04-01 00:00:00

abstract：PURPOSE:Efficacy of multi-disciplinary weight management (MDM) in youth has not been compared to their routine care. OBJECTIVES:To compare body mass index z-score (zBMI) and blood test (lab) changes (Δ) in youth before and after MDM and to correlate bio-impedance analysis (BIA) and lab measurements. METHODS:We compar...

journal_title：Endocrine

authors： Majumdar I,Espino B,Bianco K,Epstein J,Mamilly L,Harmon CM

更新日期：2019-08-01 00:00:00

abstract：:Protocols for induction of hyperthyroidism in mice are highly variable and mostly involve short-term thyroid hormone (TH) treatment. In addition, little is known about a possible influence of sex on experimental TH manipulation. Here we analyzed the efficacy of intraperitoneal vs. oral levothyroxine (T4) administratio...

journal_title：Endocrine

authors： Engels K,Rakov H,Zwanziger D,Hönes GS,Rehders M,Brix K,Köhrle J,Möller LC,Führer D

更新日期：2016-10-01 00:00:00

abstract：:Gonadotropin-releasing hormone (GnRH) effects on the lactotroph function have been widely studied, but they probably result from paracrine interactions. No visual data about GnRH receptor in the pituitary are available. In order to identify the GnRH target cells in the pituitary of adult rats, the cellular distributio...

journal_title：Endocrine

authors： Mertani HC,Testart C,Ouhtit A,Brisson C,Morel G

更新日期：1996-04-01 00:00:00

abstract：:The goal of the present study was to investigate whether p53 antibodies (Abs) could be a relevant marker for papillary thyroid carcinoma (PTC). Three types of enzyme-linked immunosorbent assay (ELISA) methods were developed for the detection of p53 Abs, including p53-ELISA, phage-SS-ELISA, and phage-SP-ELISA. A total ...

journal_title：Endocrine

authors： Pan P,Han X,Li F,Fu Q,Gao X,Sun H,Wang L

更新日期：2014-11-01 00:00:00

abstract：:Silent information regulator T1 (SIRT1) plays several key roles in the regulation of lipid and glucose homoeostasis. In this study, we investigated the potential role of SIRT1 in hyperuricemia and explored possible mechanisms. Significant hyperuricemia was detected in C57BL/6 mice treated with oxonate and yeast polysa...

journal_title：Endocrine

authors： Wang J,Zhu XX,Liu L,Xue Y,Yang X,Zou HJ

更新日期：2016-08-01 00:00:00

abstract：:Recently, the microhistologic evaluation by core needle biopsy (CNB) has been reported as high accurate to diagnose thyroid nodules with previous indeterminate or not adequate fine-needle aspiration cytology. In addition, sparse data have been reported regarding the use of CNB in other conditions. Aim of this review w...

journal_title：Endocrine

authors： Trimboli P,Crescenzi A

更新日期：2015-04-01 00:00:00

abstract：INTRODUCTION:Primary autoimmune hypophysitis (PAHs) is a rare inflammatory disease of the pituitary gland. Although largely investigated, the pathogenesis of PAH is not completely clarified. We aimed to investigate the immune response in PAHs. MATERIAL AND METHODS:Serum anti-pituitary and anti-hypothalamus antibodies ...

journal_title：Endocrine

authors： Chiloiro S,Giampietro A,Angelini F,Arena V,Stigliano E,Tartaglione T,Mattogno PP,D'Alessandris QG,Lauretti L,Pontecorvi A,De Marinis L,Bianchi A

更新日期：2021-01-23 00:00:00

abstract：:Although ghrelin in cord blood has been associated to birth weight, its role in fetal and postnatal growth has not been elucidated. The aim of this study was to analyze total ghrelin, acyl ghrelin (AG), and des-acyl ghrelin (DAG) in cord blood of newborns with idiopathic birth weight alterations, and to evaluate prote...

journal_title：Endocrine

authors： González-Domínguez MI,Lazo-de-la-Vega-Monroy ML,Zaina S,Sabanero M,Daza-Benítez L,Malacara JM,Barbosa-Sabanero G

更新日期：2016-07-01 00:00:00

abstract：PURPOSE:An increasing body of evidence suggests that dipeptidyl-peptidase 4 (DPP-4) inhibitors could play a role in the development of bullous pemphigoid. The knowledge regarding this association is based on case reports, pharmacovigilance database analyses, and observational studies. Data from randomized clinical tria...

journal_title：Endocrine

authors： Silverii GA,Dicembrini I,Nreu B,Montereggi C,Mannucci E,Monami M

更新日期：2020-09-01 00:00:00

abstract：PURPOSE:Fatty acid binding protein 4 (FABP4) has been demonstrated to be secreted from adipocytes in an unconventional pathway associated with lipolysis. Circulating FABP4 is elevated in metabolic disorders and has been shown to affect various peripheral cells such as pancreatic β-cells, hepatocytes and macrophages, bu...

journal_title：Endocrine

authors： Dou HX,Wang T,Su HX,Gao DD,Xu YC,Li YX,Wang HY

更新日期：2020-03-01 00:00:00

abstract：:Various factors influence quality of life (QoL) in acromegaly. Whether disease control and treatment approach are related to QoL is still a matter of debate. The aim of the present study was to evaluate QoL in patients with acromegaly using the disease-specific Acromegaly Quality of Life Questionnaire in respect to di...

journal_title：Endocrine

authors： Vandeva S,Yaneva M,Natchev E,Elenkova A,Kalinov K,Zacharieva S

更新日期：2015-08-01 00:00:00

abstract：:For analyzing the changes in immunoglobulins, HSP70, ghrelin levels in blood samples were collected from volunteers vaccinated against swine flu before the vaccinations and on days 3, and 15, and 1 and 2 months after the vaccination in the presence or absence of fever associated with the it. The study included 11 subj...

journal_title：Endocrine

authors： Aydin S,Guven T,Sahin İ,Aksoy A,Kendir Y,İlhan MN,Citil C,Catak Z,Ustun C

更新日期：2012-10-01 00:00:00

abstract：PURPOSES:Parathyroid cancer (PC) is rare, but fatal condition. Preoperative prediction of PC remains challenging but meaningful. The aim of this study was to determine an effective model to predict PC in patients with parathyroid lesions >1.5 cm. METHODS:In this retrospective case-control study, we enrolled 30 patient...

journal_title：Endocrine

authors： Liu R,Xia Y,Chen C,Ye T,Huang X,Ma L,Hu Y,Jiang Y

更新日期：2019-12-01 00:00:00

abstract：:The diagnostic performance of positron emission tomography using ¹¹C-methionine (MET-PET) in detecting parathyroid adenoma has been investigated by several studies with conflicting results. Aim of our study is to meta-analyze published data about this topic. A comprehensive computer literature search of studies publis...

journal_title：Endocrine

authors： Caldarella C,Treglia G,Isgrò MA,Giordano A

更新日期：2013-02-01 00:00:00

abstract：:We have linked two human chorionic gonadotropin (hCG) beta-subunit cDNAs in tandem such that the expressed fusion protein consists of two mature beta-subunits joined through the carboxy terminal peptide of the first beta-subunit. A single glycine residue is inserted between the two subunits in the fusion protein. Chin...

journal_title：Endocrine

authors： Lobel L,Pollak S,Wang S,Chaney M,Lustbader JW

更新日期：1999-06-01 00:00:00

abstract：:Altered bone micro-architecture is an important factor in accounting for fragility fractures. Until recently, it has not been possible to gain information about skeletal microstructure in a way that is clinically feasible. Bone biopsy is essentially a research tool. High-resolution peripheral Quantitative Computed Tom...

journal_title：Endocrine

authors： Ulivieri FM,Silva BC,Sardanelli F,Hans D,Bilezikian JP,Caudarella R

更新日期：2014-11-01 00:00:00

abstract：:Variants of growth hormone (GH) are present in most vertebrates. Chicken GH (cGH) undergoes posttranslational modifications that contribute to its structural diversity. Although the 22-kDa form of GH is the most abundant, some other variants have discrete bioactivities that may not be shared by others. The proportion ...

journal_title：Endocrine

authors： Martínez-Coria H,López-Rosales LJ,Carranza M,Berumen L,Luna M,Arámburo C

更新日期：2002-03-01 00:00:00

abstract：:In arthropods, development is controlled by cholesterol-derived steroid hormones: the ecdysteroids. In vertebrates and insects, steroidogenesis is positively regulated and this is mediated by cAMP. In crustaceans, ecdysteroid biosynthesis by steroidogenic organs (Y-organs) is negatively regulated by a neuropeptide, th...

journal_title：Endocrine

authors： Lachaise F,Sommé G,Carpentier G,Granjeon E,Webster S,Baghdassarian D

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND:Low mineral mass and reduced bone strength with increased fracture risk are the main causes of morbidity in Thalassemia Major (TM). The pathogenesis is multifactorial and includes ineffective erythropoiesis with medullary expansion, multiple endocrine dysfunctions, direct iron bone deposition, deferoxamine-i...

journal_title：Endocrine

authors： Pellegrino F,Zatelli MC,Bondanelli M,Carnevale A,Cittanti C,Fortini M,Gamberini MR,Giganti M,Ambrosio MR

更新日期：2019-09-01 00:00:00

abstract：:Quality of life (QoL) is an important aspect that reflects the way people feel and function. The assessment of QoL quality of life is an essential tool for estimating the efficacy of any therapy in different pathophysiological conditions. In normal, healthy women, the perception of QoL can be significantly modified du...

journal_title：Endocrine

authors： Gambacciani M

更新日期：2004-08-01 00:00:00

abstract：PURPOSE:The hyperthermal liquid, spray and smog caused by energy-based surgical devices (EBDs) may be the potential risk factors for recurrent laryngeal nerve (RLN) thermal injury, but not been reported previously. We aim to demonstrated it both in thyroid surgeries and animal experiments. METHODS:321 thyroid patients...

journal_title：Endocrine

authors： Yu X,Liu C,Yan M,Gong W,Wang Y

更新日期：2020-08-10 00:00:00

abstract：PURPOSE:Multiple endocrine neoplasia type 1 is a rare tumor syndrome caused by germline mutations of MEN1 gene. Phenotype varies widely, and no definitive correlation with the genotype has been observed. Mutation-negative patients with MEN1-associated tumors represent phenocopies. By comparing mutation-positive and mut...

journal_title：Endocrine

authors： Kövesdi A,Tóth M,Butz H,Szücs N,Sármán B,Pusztai P,Tőke J,Reismann P,Fáklya M,Tóth G,Somogyi A,Borka K,Erdei A,Nagy EV,Deák V,Valkusz Z,Igaz P,Patócs A,Grolmusz VK

更新日期：2019-08-01 00:00:00

abstract：:Graves' disease, an autoimmune disease with heterogeneous symptoms including Graves' orbitopathy, has a combined genetic/environmental background, where variations within CD28/CTLA-4/ICOS genes are considered as disease markers.Association of CD28c.17+3T>C(rs3116496), CTLA-4g.319C>T(rs5742909), CTLA-4c.49A>G(rs231775)...

journal_title：Endocrine

authors： Pawlak-Adamska E,Frydecka I,Bolanowski M,Tomkiewicz A,Jonkisz A,Karabon L,Partyka A,Nowak O,Szalinski M,Daroszewski J

更新日期：2017-01-01 00:00:00

abstract：PURPOSE:Bone may regulate glucose homeostasis via uncarboxylated bioactive osteocalcin (ucOCN). This study explored whether changes in ucOCN and bone remodeling are associated with change in glucose homeostasis after biliopancreatic diversion (BPD). METHODS:In this secondary exploratory analysis of a 1-year prospectiv...

journal_title：Endocrine

authors： Turcotte AF,Grenier-Larouche T,Lacombe J,Carreau AM,Carpentier AC,Mac-Way F,Tchernof A,Richard D,Biertho L,Lebel S,Marceau S,Ferron M,Gagnon C

更新日期：2020-09-01 00:00:00

abstract：PURPOSE:We exploited the MassARRAY (MA) genotyping platform to develop the "PTC-MA assay", which allows the simultaneous detection of 13 hotspot mutations, in the BRAF, KRAS, NRAS, HRAS, TERT, AKT1, PIK3CA, and EIF1AX genes, and six recurrent genetic rearrangements, involving the RET and TRK genes in papillary thyroid ...

journal_title：Endocrine

authors： Pesenti C,Muzza M,Colombo C,Proverbio MC,Farè C,Ferrero S,Miozzo M,Fugazzola L,Tabano S

更新日期：2018-07-01 00:00:00

abstract：:The best repletion and maintenance dosing regimens with cholecalciferol in vitamin D-deficient HIV-1 patients remain unknown. Protease inhibitors (PIs) have been shown to inhibit vitamin D 1α- and 25α-hydroxylation in hepatocyte and monocyte cultures. We therefore evaluated the effect of a single high dose of cholecal...

journal_title：Endocrine

authors： Pepe J,Mezzaroma I,Fantauzzi A,Falciano M,Salotti A,Di Traglia M,Diacinti D,Biondi P,Cipriani C,Cilli M,Minisola S

更新日期：2016-07-01 00:00:00

abstract：:Tumor suppressor p53 is a transcriptional factor that determines cell fate in response to multiple stressors, such as oxidative stress and endoplasmic reticulum stress, in the majority of cells. However, its role in pancreatic beta cells is not well documented. Our previous research has revealed that glycation-serum (...

journal_title：Endocrine

authors： Li Y,Zhang T,Huang Q,Sun Y,Chang X,Zhang H,Zhu Y,Han X

更新日期：2016-11-01 00:00:00