Abstract:
:In the Department of Respiratory Medicine, North Staffordshire Hospital, patients fulfilling the Department of Health criteria for long-term oxygen therapy (LTOT) attend a practical teaching session on the use of their oxygen concentrator before commencing therapy. In the present study, we have audited the prescribing of LTOT in all patients in three health districts in the North West Midlands reviewed between June 1992 and July 1994. They were split into two groups. The first had the assessment and training programme in the department. Patients in the control group had been prescribed LTOT from outside the department without any formal training. In both groups of patients information was collated 6 months after starting LTOT by means of a questionnaire assessing patients', understanding of both their need for oxygen and their disease process, the dangers of oxygen therapy and present smoking habit. Objective information about the usage of each concentrator was obtained from engineer reports. Thirty-six patients (eight from the trained group and 28 controls) died before evaluation at 6 months. Forty-five patients (29 male, mean age 71 years) received training and 41 control patients (24 male, mean age 72 years) were evaluated. Thirty-seven (82%) patients who had received formal training were using their concentrator for greater than 15 h compared with only 18 (44%) of the controls (P = 0.0002). Forty-two (93%) patients who had received training understood why they were using LTOT compared with only 17 (41%) in the control group (P = 0.00001). Although both groups had a similar understanding of the dangers of smoking while on oxygen therapy, six (15%) of the control group were smoking as compared to only one (2%) of the trained group (P = 0.038). One of the control patients had received significant facial burns as a direct result of smoking while on oxygen. Further efforts are required to ensure that all patients prescribed LTOT should have a formal respiratory assessment as well as training to improve compliance and to obtain maximal benefits from such therapy.
journal_name
Respir Medjournal_title
Respiratory medicineauthors
Peckham DG,McGibbon K,Tonkinson J,Plimbley G,Pantin Cdoi
10.1016/s0954-6111(98)90422-xsubject
Has Abstractpub_date
1998-10-01 00:00:00pages
1203-6issue
10eissn
0954-6111issn
1532-3064pii
S0954-6111(98)90422-Xjournal_volume
92pub_type
杂志文章abstract:INTRODUCTION:Polymerase chain reaction (PCR)-based techniques to detect Mycobacterium tuberculosis DNA in respiratory specimens have been increasingly used to diagnose pulmonary tuberculosis. Their use in non-respiratory specimens to diagnose extrapulmonary tuberculosis is, however, controversial. In this study, we est...
journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/j.rmed.2014.04.007
更新日期:2014-06-01 00:00:00
abstract::A previous study in the Liverpool district on patients receiving long term oxygen treatment using a domiciliary oxygen concentrator showed that only 55% were both using oxygen therapy correctly and had stopped smoking. To try and identify which factors influence patient behaviour, all 55 patients in this district rece...
journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/s0954-6111(08)80062-5
更新日期:1990-07-01 00:00:00
abstract::Samples of lung tissue, taken at time of lung transplant, from 13 Dutch Caucasian patients with idiopathic pulmonary arterial hypertension (iPAH) and 14 patients with non-idiopathic PAH were studied for the presence of human herpes virus-8 (HHV-8). By immunohistochemical staining, in none of patients expression of HHV...
journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/j.rmed.2006.08.015
更新日期:2007-04-01 00:00:00
abstract::Preterm infants who are symptomatic at follow-up frequently have a high airways resistance (RAW) and a low functional residual capacity to thoracic gas volume ratio (FRC:TGV). The aim of this study was to assess the effect of bronchodilator therapy on these lung function abnormalities. Thirty-four infants who had recu...
journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/0954-6111(94)90057-4
更新日期:1994-04-01 00:00:00
abstract:BACKGROUND:Many patients with DMD undergo tracheostomy. Tracheostomy is associated with certain complications, however its effect on prognosis is not known. METHODS:The relationship between type of mechanical ventilation and survival at 12 years was evaluated in a prospective cohort of patients with Duchenne muscular ...
journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/j.rmed.2016.04.009
更新日期:2016-06-01 00:00:00
abstract::In developing countries, many sputum-negative suspects of pulmonary tuberculosis (PTB) are given antituberculous medication just because tuberculosis (TB) could not be excluded in them. Many studies have shown that BCG test is nearly 100% sensitive, except in those with severe malnutrition, steroid therapy and other c...
journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1053/rmed.2003.1478
更新日期:2003-05-01 00:00:00
abstract:BACKGROUND:Patients with Chronic Obstructive Pulmonary Disease with chronic respiratory failure (COPD-CRF) experience high mortality and healthcare utilization. Non-invasive home ventilation (NIVH) is increasingly used in such patients. We examined the associations between NIVH and survival, hospitalizations, and emerg...
journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/j.rmed.2020.106291
更新日期:2020-12-30 00:00:00
abstract:BACKGROUND:Reduction in 30-day readmission rate after chronic obstructive pulmonary disease (COPD)-related hospitalization is a national objective. However, little is known about trends in readmission rates in recent years, particularly in priority populations defined by the Agency for Healthcare Research and Quality (...
journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/j.rmed.2017.07.058
更新日期:2017-09-01 00:00:00
abstract::Haemodynamic studies at rest and during exercise together with radionuclide ventriculography, pulmonary function and clinical well-being assessment were evaluated in ten patients with COPD and secondary pulmonary hypertension (mean PAP 25 mm Hg), before and after 6 months therapy with pirbuterol 20 mg thrice daily. De...
journal_title:Respiratory medicine
pub_type: 临床试验,杂志文章
doi:10.1016/s0954-6111(89)80061-7
更新日期:1989-01-01 00:00:00
abstract::The records of a total of 497 patients notified to have active tuberculosis (TB) in Western Australia from 1986 to 1990 inclusive have been reviewed in relation to case-finding. Of these, 276 (55.5%) were Asian migrants, 92 (18.5%) Europeans and 110 (22.1%) Australians. The disease was confirmed bacteriologically in 2...
journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/s0954-6111(05)80349-x
更新日期:1994-03-01 00:00:00
abstract:BACKGROUND:Discrepancies have been observed between clinical, physiological, and inflammatory asthma control criteria, mostly in asthmatic subjects using regular inhaled corticosteroids (ICS) treatment. This study compared the prevalence of discrepancies between these 3 control parameters in mild asthmatic subjects not...
journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/j.rmed.2012.12.015
更新日期:2013-04-01 00:00:00
abstract:OBJECTIVE:To examine medication adherence and persistence among COPD patients during their last year of life. DATA SOURCE:National VA databases were used to identify patients who had COPD and died between 1999 and 2003. STUDY DESIGN:We examined use of inhaled corticosteroids (ICS), long acting beta(2) agonists (LABA)...
journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/j.rmed.2008.11.004
更新日期:2009-04-01 00:00:00
abstract:OBJECTIVE:To compare the value of closed percutaneous pleural biopsy versus pleuroscopy for diagnosis of undiagnosed exudative pleural effusion in an age-dependent manner. DESIGN:Prospective clinical study. SETTING:University hospitals. PATIENTS:Forty-nine consecutive patients with undiagnosed exudative pleural effu...
journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/s0954-6111(98)90296-7
更新日期:1998-03-01 00:00:00
abstract::The differential diagnosis of pleural masses is limited. Asbestos-related disease and invasive bronchogenic carcinoma make up the majority of cases. The diagnostic yield of biopsies is low, and invasive procedures are often required to achieve diagnosis. A variety of imaging techniques are available to help differenti...
journal_title:Respiratory medicine
pub_type: 杂志文章,评审
doi:10.1016/j.rmed.2007.11.010
更新日期:2008-03-01 00:00:00
abstract:BACKGROUND:Lung deposition of inhaled steroids, likely to be of benefit in the anti-inflammatory treatment of asthma in young children, is low. This is explained by age specific anatomical and physiological characteristics as well as poor cooperation with aerosol therapy. However, total lung deposition and the ratio of...
journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/j.rmed.2009.04.029
更新日期:2009-11-01 00:00:00
abstract:OBJECTIVE:to describe the clinical manifestations and survival of patients with ILD and myositis-specific and associated autoantibodies, and to evaluate the performance of the new ATS/ERS classification criteria for IPAF. PATIENTS AND METHODS:Patients with ILD and positive in at least one of the following autoantibodi...
journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/j.rmed.2016.12.014
更新日期:2017-02-01 00:00:00
abstract::The role of short-term tests of reversibility in selecting patients with COAD for long-term nebuliser therapy is uncertain. In a double-blind placebo-controlled crossover study we have examined the correlation between short-term reversibility and response to a home nebuliser. We studied 20 patients with severe COAD (m...
journal_title:Respiratory medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0954-6111(06)80097-1
更新日期:1991-07-01 00:00:00
abstract:BACKGROUND:Aspirin desensitization (AD) is an effective and safe therapeutic option for patients with nonsteroidal anti-inflammatory drugs (NSAIDs)-exacerbated respiratory disease (N-ERD). The mechanisms driving its beneficial effects remain poorly understood. OBJECTIVE:To investigate the effect of long-term AD on cli...
journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/j.rmed.2019.04.021
更新日期:2019-06-01 00:00:00
abstract::Late allergic reactions (LAR) following allergen challenge occur in different compartments. We studied the kinetics of nasal and bronchial nitric oxide (NO) in mild asthmatics after allergen challenge. Twelve males with intermittent asthma (28 yr, FEV1 97% of predicted, PC20methacholine <8 mg/ml) and known LAR after b...
journal_title:Respiratory medicine
pub_type: 临床试验,杂志文章
doi:10.1016/j.rmed.2005.03.029
更新日期:2005-12-01 00:00:00
abstract:INTRODUCTION:Antibodies against mimivirus, a recently discovered giant virus, have been found in patients presenting with pneumonia suggesting a potential role for this virus as a respiratory pathogen. Several bacterial and viral pathogens have been associated with the occurrence of acute exacerbations in COPD. However...
journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/j.rmed.2012.08.019
更新日期:2012-12-01 00:00:00
abstract::Inhaled lignocaine appeared to have considerable steroid sparing properties in an uncontrolled trial in 20 patients with oral-steroid-dependent asthma. Since it can also cause bronchoconstriction, safety needs to be studied under controlled conditions. We have performed a randomized, double-blind, placebo-controlled s...
journal_title:Respiratory medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0954-6111(98)90142-1
更新日期:1998-12-01 00:00:00
abstract:BACKGROUND:Smoking and obesity might alter the risk of sarcoidosis. However, the data remained inconclusive. METHODS:A cohort of Olmsted County, Minnesota residents diagnosed with sarcoidosis between January 1, 1976 and December 31, 2013 was identified based on individual medical record review. For each sarcoidosis su...
journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/j.rmed.2016.10.003
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:Cystic Fibrosis (CF) is the most common life limiting genetic disorder, characterized by chronic respiratory failure secondary to inflammation and chronic bacterial lung infection. Pseudomonas aeruginosa lung infection is associated with more severe lung disease and rapid progression of respiratory failure w...
journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/j.rmed.2019.04.012
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:Breathlessness and exercise intolerance frequently impact the daily life of patients with COPD. METHODS:This double-blind, multicentre, three-period crossover study randomised 111 patients with COPD (mean age 64 years, mean FEV(1) 38% of predicted normal) to budesonide/formoterol 320/9 microg, formoterol 9 ...
journal_title:Respiratory medicine
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.rmed.2010.07.006
更新日期:2010-10-01 00:00:00
abstract::Turbuhaler has a very high resistance hence patient inhalation flow when using it would be low. The total emitted dose (TED) of 500microg terbutaline sulphate from a Bricanyl Turbuhaler was determined using a range of inhalation flows (10-60L min(-1)) with inhalation volume of 2 and 4L using a DPI sampling apparatus a...
journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/j.rmed.2009.11.014
更新日期:2010-05-01 00:00:00
abstract::Patients with chronic obstructive pulmonary disease (COPD) are often characterised by a range of characteristic co-morbidities that interfere with their pulmonary disease. In addition to a mere association with co-morbidities, a complex pathophysiological interaction and mutual augmentation occurs between COPD and its...
journal_title:Respiratory medicine
pub_type: 杂志文章,评审
doi:10.1016/S0954-6111(11)70005-1
更新日期:2011-10-01 00:00:00
abstract::The present study investigated, for the first time, the long-term prognosis of hypersensitivity type of occupational laryngitis (OL). Thirteen patients with OL diagnosed in 1990-1993 at the Finnish Institute of Occupational Health participated in a questionnaire follow-up study. The records of the primary diagnostic i...
journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/j.rmed.2008.07.015
更新日期:2009-01-01 00:00:00
abstract::The role of positive end-expiratory pressure (PEEP) in the postoperative course of cardiac surgery patients remains questionable. In this prospective study, we examined the effect of different levels of PEEP on arterial oxygenation, SvO2 and PvO2 values, and on haemodynamic indices, during the early postoperative peri...
journal_title:Respiratory medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0954-6111(98)90388-2
更新日期:1998-06-01 00:00:00
abstract::The aim of the present investigation was to evaluate the predictive value of a symptom-limited exercise test in predicting postoperative morbidity and mortality in patients submitted to pneumonectomy. The study was conducted in 150 patients (mean age, 57.1). Forty-four patients (29.3%) had postoperative complications....
journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/j.rmed.2003.07.004
更新日期:2003-12-01 00:00:00
abstract::In high-school students, prevalence of smoking is high but few studies analyzed smoking in the student population according to nicotine content of smoked cigarettes and gender. We analyzed the responses to a questionnaire, including the modified Fagerström Tolerance Questionnaire (FTQ), administered to 555 students (3...
journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/j.rmed.2005.02.006
更新日期:2005-08-01 00:00:00