Neurological and endocrinological disorders: orphans in chronic obstructive pulmonary disease.

abstract：:Subjects with chronic obstructive airways disease may have difficulty with the roadside alcolmeter. Twenty-six subjects with a FEV1/FVC less than 60% were asked to use an alcolmeter simulator. Only ten were able to produce the necessary flow rate of 28 l min-1 for a minimum of 2.7 s, two could produce the same total v...

journal_title：Respiratory medicine

authors： Briggs JE,Patel H,Butterfield K,Honeybourne D

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) is a common disease worldwide with significant morbidity and mortality. AIM:To investigate the effect of a comprehensive COPD management programme in decreasing COPD readmissions 1 year before and 1 year after the programme. METHOD:185 (166 males) patients admit...

journal_title：Respiratory medicine

authors： Ko FW,Ngai JC,Ng SS,Chan KP,Cheung R,Leung MY,Pun MC,Hui DS

更新日期：2014-12-01 00:00:00

abstract：INTRODUCTION:Exhaled nitric oxide (FE(NO)) is a reliable non-invasive marker of airway inflammation. In 2003 FE(NO) chemiluminescence analyzer (NIOX; Aerocrine AB, Solna, Sweden) was approved by U.S. Food and Drug Administration for monitoring asthma therapy. Recently, the same company developed a portable device using...

journal_title：Respiratory medicine

authors： Pizzimenti S,Bugiani M,Piccioni P,Heffler E,Carosso A,Guida G,Rolla G

更新日期：2008-09-01 00:00:00

abstract：:In a double-blind study of 60 patients undergoing fibreoptic bronchoscopy we have compared the local anaesthetic effects of intratracheal injections of cocaine (4 ml, 2.5%) and lignocaine (4 ml, 4%). The two local anaesthetics were equally effective in terms of cough suppression, requirement for extra local anaestheti...

journal_title：Respiratory medicine

authors： Teale C,Gomes PJ,Muers MF,Pearson SB

更新日期：1990-09-01 00:00:00

abstract：:In this study healthy never-smoking subjects (n = 18) were recruited from a population study. Bronchoalveolar lavage (BAL), blood lymphocytes and bronchial biopsies, analysed both in the epithelium and lamina propria, were stained for T and B lymphocytes, natural killer (NK) cells and different subpopulations of T lym...

journal_title：Respiratory medicine

authors： Ekberg-Jansson A,Arvå E,Nilsson O,Löfdahl CG,Andersson B

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:Slovenia is one of the few countries where IS6110 RFLP is applied for genotyping M. tuberculosis at a nationwide level, which has been in effect since 2000. Based on S6110 RFLP clustering, typical risk factors and routes of M. tuberculosis transmission were identified, such as alcohol abuse, homelessness, an...

journal_title：Respiratory medicine

authors： Bidovec-Stojkovic U,Zolnir-Dovc M,Supply P

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:A predominant feature of asthma is an accelerated rate of decline in forced expiratory volume in 1 s (FEV1), but data on the variability and factors associated with this change in patients with controlled asthma are largely unknown. METHODS:140 patients with controlled asthma were enrolled based on the Glob...

journal_title：Respiratory medicine

authors： Matsunaga K,Ichikawa T,Oka A,Morishita Y,Kanai K,Hiramatsu M,Akamatsu H,Kawabata H,Kikuchi T,Akamatsu K,Hirano T,Kou Y,Nakanishi M,Minakata Y,Yamamoto N

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Limited data are available as to the relationship between computed tomography (CT) derived data on emphysema and airway wall thickness, and quality of life in subjects with chronic obstructive pulmonary disease (COPD). Such data may work to clarify the clinical correlate of the CT findings. METHODS:We inclu...

journal_title：Respiratory medicine

authors： Gietema HA,Edwards LD,Coxson HO,Bakke PS,ECLIPSE Investigators.

更新日期：2013-08-01 00:00:00

abstract：:The present study investigates the influence of COPD on attention functions, learning, and logical thinking. Therefore, 60 COPD patients and 60 healthy controls were recruited into a cross-sectional study and underwent extensive neuropsychological testing. The Attention Network Test was used for assessment of tonic an...

journal_title：Respiratory medicine

authors： Klein M,Gauggel S,Sachs G,Pohl W

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Severe asthma is a heterogeneous disease. Patients with both eosinophilic and allergic asthma phenotypes may be eligible for treatment with mepolizumab and omalizumab. Evidence on the relative effectiveness of these treatments in this 'overlap' population would be informative for clinical and payer decision ...

journal_title：Respiratory medicine

authors： Cockle SM,Stynes G,Gunsoy NB,Parks D,Alfonso-Cristancho R,Wex J,Bradford ES,Albers FC,Willson J

更新日期：2017-02-01 00:00:00

abstract：:Exposure to mushroom spores may cause many respiratory allergic diseases, however, there has been no serial study in a mushroom factory to address this problem. The aim of this study was to investigate the serial changes in respiratory allergy and the incidence of hypersensitivity pneumonitis (HP) in mushroom workers....

journal_title：Respiratory medicine

authors： Tanaka H,Saikai T,Sugawara H,Tsunematsu K,Takeya I,Koba H,Matsuura A,Imai K,Abe S

更新日期：2001-12-01 00:00:00

abstract：:Lung function in cases of chronic airflow obstruction (CAO) due to tuberculous destroyed lung, which is still common in Korea, has not been objectively investigated. We evaluated lung functions and postbronchodilator responses in 21 CAO patients with a forced expiratory volume in 1 s (FEV1) of 30-65% of the predicted ...

journal_title：Respiratory medicine

authors： Lee JH,Chang JH

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Although athletes have a high prevalence of airway hyperresponsiveness (AHR) and asthma, little is known about possible gender differences in regard to these features. We looked at the comparative prevalence of AHR, physician-diagnosed asthma and respiratory symptoms during exercise in female (F) and male (M...

journal_title：Respiratory medicine

authors： Langdeau JB,Day A,Turcotte H,Boulet LP

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Smoking and obesity might alter the risk of sarcoidosis. However, the data remained inconclusive. METHODS:A cohort of Olmsted County, Minnesota residents diagnosed with sarcoidosis between January 1, 1976 and December 31, 2013 was identified based on individual medical record review. For each sarcoidosis su...

journal_title：Respiratory medicine

authors： Ungprasert P,Crowson CS,Matteson EL

更新日期：2016-11-01 00:00:00

abstract：INTRODUCTION:According to current GOLD strategy, patients with COPD classified as groups A and B may be treated with inhaled bronchodilators, either long-acting β2-agonist (LABA) or long-acting muscarinic antagonist (LAMA). However, there is little guidance on which class of agent is preferred and a lack of prospective...

journal_title：Respiratory medicine

authors： Mahler DA,Kerstjens HA,Donohue JF,Buhl R,Lawrence D,Altman P

更新日期：2015-08-01 00:00:00

abstract：:Limited knowledge exists about development of bronchial hyperresponsiveness (BHR) through adolescence. We aimed to assess changes in and risk factors for BHR in adolescence. From a Norwegian birth cohort 517 subjects underwent clinical examinations, structured interviews and methacholine challenges at age 10 and 16. B...

journal_title：Respiratory medicine

authors： Riiser A,Hovland V,Mowinckel P,Carlsen KH,Carlsen KL

更新日期：2012-02-01 00:00:00

abstract：:To answer the question as to whether pulmonary rehabilitation programs (PRP) induced increase in exercise tolerance (ET) is associated with increased levels of exhaled nitric oxide (eNO) in COPD patients of different degrees of severity, we designed a prospective and controlled study. Forty-seven stable COPD patients ...

journal_title：Respiratory medicine

authors： Clini E,Bianchi L,Foglio K,Vitacca M,Ambrosino N

更新日期：2002-05-01 00:00:00

abstract：:Fifty patients with tropical eosinophilia were studied clinically and physiologically, before and after a standard 3-week course of diethylcarbamazine. Before treatment the main physiological abnormality was a reduction in the carbon monoxide transfer factor. One month after the start of treatment most patients had sh...

journal_title：Respiratory medicine

authors： Vijayan VK,Rao KV,Sankaran K,Venkatesan P,Prabhakar R

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Exercise induced asthma may symptomatically be difficult to differentiate from exercise related obstruction in the upper airways, sometimes leading to diagnostic confusion and inappropriate treatment. Larynx accounts for a significant fraction of total airway resistance, but its role as a limiting factor for...

journal_title：Respiratory medicine

authors： Røksund OD,Maat RC,Heimdal JH,Olofsson J,Skadberg BT,Halvorsen T

更新日期：2009-12-01 00:00:00

abstract：:The sputum smear-negative patients have been a diagnostic challenge for health professionals. Adenosine deaminase (ADA) activity has been shown to rise in various body fluids of patients with tuberculosis (Tb). A prospective clinical trial was conducted to determine the diagnostic value of ADA activity in bronchoalveo...

journal_title：Respiratory medicine

authors： Kayacan O,Karnak D,Delibalta M,Beder S,Karaca L,Tutkak H

更新日期：2002-07-01 00:00:00

abstract：RATIONALE:Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive fibrosing interstitial pneumonia. The pathogenicity of IPF has been widely investigated but still remains to be clarified. Efferocytosis, the specialized recognition and ingestion of apoptotic cells by phagocytes, is essential for the resolution of...

journal_title：Respiratory medicine

authors： Morimoto K,Janssen WJ,Terada M

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Respiratory complaints after exercise are common in patients with rhinitis. Exercise-induced bronchospasm (EIB) may be one of the causes. OBJECTIVES:To evaluate EIB prevalence in a group of children and adolescents with allergic rhinitis, to compare the treadmill running (TR) and eucapnic voluntary hyperven...

journal_title：Respiratory medicine

authors： Albuquerque Rodrigues Filho E,Rizzo JÂ,Gonçalves AV,Correia Junior MAV,Sarinho ESC,Medeiros D

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:We hypothesized that the peculiar mixed interleukin-4 (IL-4/Th2) and interferon gamma INF-γ (INF-γ/Th1) inflammatory milieu found in the airways of patients with aspirin-exacerbated respiratory disease (AERD) is responsible for the altered regulation of the IL-1β/IL-1RI-/EP2/COX-2 autocrine loop also found i...

journal_title：Respiratory medicine

authors： Machado-Carvalho L,Roca-Ferrer J,Picado C

更新日期：2019-04-01 00:00:00

abstract：:Seventy-seven patients with morbid obesity, body mass index (BMI) 40-69.9 kg m(-2), who were candidates for gastroplasty, were studied in our laboratory as part of a pre-operative survey. They had no complaints other than obesity and were not cyanotic. A group of 28 lean subjects (BMI 20-29.8 kg m(-2)) who were candid...

journal_title：Respiratory medicine

authors： Ladosky W,Botelho MA,Albuquerque JP Jr

更新日期：2001-04-01 00:00:00

abstract：:Nasal mucociliary system is the first line of defense of the upper airways and may be affected acutely by exposure to particulate matter (PM) from biomass burning. Several epidemiologic studies have demonstrated a consistent association between levels of air pollution from biomass burning with increases in hospitaliza...

journal_title：Respiratory medicine

authors： Ferreira-Ceccato AD,Ramos EM,de Carvalho LC Jr,Xavier RF,Teixeira MF,Raymundo-Pereira PA,Proença Cdos A,de Toledo AC,Ramos D

更新日期：2011-11-01 00:00:00

abstract：:The objective of this study was to compare bronchial challenge tests with two substances [histamine (H) and methacholine (M)] and two methods of measuring the effect parameter FEV1 and pulmonary impedance [with the forced oscillation technique (FOT)] in order to determine which test is the shortest, and gives the leas...

journal_title：Respiratory medicine

authors： Weersink EJ,vd Elshout FJ,van Herwaarden CV,Folgering H

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:International guidelines recommend simple spirometry for bronchiectasis patients. However, pulmonary pathophysiology of bronchiectasis is very complex and still poorly understood. Our objective was to characterize lung function in bronchiectasis and identify specific functional sub-groups. METHODS:This was ...

journal_title：Respiratory medicine

authors： Radovanovic D,Santus P,Blasi F,Sotgiu G,D'Arcangelo F,Simonetta E,Contarini M,Franceschi E,Goeminne PC,Chalmers JD,Aliberti S

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:There has not been a comprehensive multi-center study investigating the microbial profile of community acquired pneumonia (CAP) in Taiwan. METHODS:A prospective study of adult CAP patients requiring hospitalization between December 2001 and April 2002 was carried out in 13 hospitals in Taiwan. Etiology was ...

journal_title：Respiratory medicine

authors： Lauderdale TL,Chang FY,Ben RJ,Yin HC,Ni YH,Tsai JW,Cheng SH,Wang JT,Liu YC,Cheng YW,Chen ST,Fung CP,Chuang YC,Cheng HP,Lu DC,Liu CJ,Huang IW,Hung CL,Hsiao CF,Ho M

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Pulmonary function testing is not feasible in many adults with intellectual disabilities, because of difficulties with understanding and cooperation. AIMS:To investigate feasibility, repeatability and reproducibility of measuring airway resistance using the interrupter technique (MicroRint) in people aged 5...

journal_title：Respiratory medicine

authors： Pouls KP,Alsema LE,van der Laan H,Evenhuis HM,Penning C

更新日期：2009-12-01 00:00:00

abstract：:The sick building syndrome has been the subject of research for approximately 10 years. Although it is often suggested that symptoms in office workers are due to circulating micro-organisms or particles, epidemiological studies investigating the relationship between them have been lacking. This cross-sectional study h...

journal_title：Respiratory medicine

authors： Harrison J,Pickering CA,Faragher EB,Austwick PK,Little SA,Lawton L

更新日期：1992-05-01 00:00:00