Severe vocal cord dysfunction resistant to all current therapeutic interventions.

abstract：:Pulmonary hypertension (PH) is a chronic cardiopulmonary disorder that if left untreated, progresses rapidly and is ultimately fatal. The World Health Organization (WHO) has classified PH into 5 distinct groups according to pathophysiology, hemodynamic characteristics, and clinical presentation. Dysfunction in the nit...

journal_title：Respiratory medicine

authors： Benza R,Mathai S,Nathan SD

更新日期：2017-01-01 00:00:00

abstract：:Viozan (sibenadet HCl, AR-C68397AA) is a novel dual D2 dopamine receptor, beta2-adrenoceptor agonist that has been investigated for efficacy in alleviating the symptoms of chronic obstructive pulmonary disease (COPD). The slowly progressive nature of this disease means that patients will require ongoing therapeutic ma...

journal_title：Respiratory medicine

authors： Hiller FC,Alderfer V,Goldman M

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Trends in prevalence of asthma and allergic diseases are still controversial, and rarely studied among adolescents at midpoint of puberty. METHODS:In 2000, a questionnaire was mailed to adolescents (n = 18,158) attending 9th grade at school and living in Västra Götaland County, Sweden. Eight years later, th...

journal_title：Respiratory medicine

authors： Kim JL,Brisman J,Aberg MA,Forslund HB,Winkvist A,Torén K

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Intermittent ICS treatment with SABA in response to symptoms, is an emerging strategy for control of mild-to-moderate asthma, and recurrent wheezing. This systematic revue compares the efficacy of daily vs. intermittent ICS among preschoolers, children and adults with persistent wheezing and mild to moderate...

journal_title：Respiratory medicine

authors： Rodrigo GJ,Castro-Rodríguez JA

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Patients with amyopathic dermatomyositis (ADM) sometimes develop rapidly progressive interstitial lung disease (ILD) predominantly in Asia. Although anti-CADM-140/MDA5 antibody titer could correlate with disease activity and predict the course of ILD associated with ADM, it is not clear how this antibody is ...

journal_title：Respiratory medicine

authors： Takada T,Aoki A,Asakawa K,Sakagami T,Moriyama H,Narita I,Sato S

更新日期：2015-09-01 00:00:00

abstract：:In this economic evaluation, conducted alongside a randomized, double-blind clinical trial, economic data were collected from 339 patients with moderate-persistent asthma randomized to receive twice-daily, double-blind treatment with budesonide/formoterol 160/4.5 microg in a single inhaler (n=166) or fluticasone propi...

journal_title：Respiratory medicine

authors： Ericsson K,Bantje TA,Huber RM,Borg S,Bateman ED

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:The presence of non-reversible airway obstruction (AO) in never smokers has only received limited attention until now. METHODS:We analyzed data from the Austrian Burden of Obstructive Lung Disease (BOLD) study. We defined non-reversible AO as post-bronchodilator FEV(1)/FVC <0.7 which corresponds to COPD I a...

journal_title：Respiratory medicine

authors： Lamprecht B,Schirnhofer L,Kaiser B,Buist S,Studnicka M

更新日期：2008-12-01 00:00:00

abstract：:Several monoclonal antibodies (mAbs) (omalizumab, mepolizumab, reslizumab, benralizumab, and dupilumab) are currently approved for the treatment of severe asthma. They have complex pharmacokinetic profiles. These profiles are unique in that they are dependent on their structure as well as can be markedly influenced by...

journal_title：Respiratory medicine

authors： Matera MG,Calzetta L,Rogliani P,Cazzola M

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Patients with severe or very severe chronic obstructive pulmonary disease (COPD) frequently suffer repeated exacerbations generating high health care utilization costs. Combined corticosteroid and bronchodilator treatment using a single inhaler might - via improved compliance - reduce exacerbation rates. OB...

journal_title：Respiratory medicine

authors： Hagedorn C,Kässner F,Banik N,Ntampakas P,Fielder K

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Sarcoidosis (SA) is a multisystem granulomatous disorder of unknown etiology. It seems likely that in genetically different predisposed hosts, the same antigen(s) may cause the development of sarcoid Th1 response. The interaction of the T-cell receptor with the human leukocyte antigen-DQA1*03011 peptide-comp...

journal_title：Respiratory medicine

authors： Dubaniewicz A,Dubaniewicz A,Dubaniewicz A,Moszkowska G

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:There are limited data on the role of adipokines in atopic asthma. AIM:To determine serum level of apelin-12 (APE-12) in asthmatic children in relation to BMI and gender. METHODS:Serum APE-12 levels were measured using ELISA in 89 asthmatic children (61 boys and 28 girls, aged 7.0-17.0 years) and in 33 hea...

journal_title：Respiratory medicine

authors： Machura E,Ziora K,Ziora D,Swiętochowska E,Krakowczyk H,Halkiewicz F,Kasperska-Zajac A

更新日期：2013-02-01 00:00:00

abstract：:The present study investigates the influence of COPD on attention functions, learning, and logical thinking. Therefore, 60 COPD patients and 60 healthy controls were recruited into a cross-sectional study and underwent extensive neuropsychological testing. The Attention Network Test was used for assessment of tonic an...

journal_title：Respiratory medicine

authors： Klein M,Gauggel S,Sachs G,Pohl W

更新日期：2010-01-01 00:00:00

abstract：:The aim of this study was to examine an acoustic reflection method using a flexible tube for identifying the obstructive site of the upper airway in snorers and patients with obstructive sleep apnoea (OSA). As a preliminary study it was performed n models and subjects in the awake state. Flextube narrowing was produce...

journal_title：Respiratory medicine

authors： Faber CE,Grymer L,Norregaard O,Hilberg O

更新日期：2001-08-01 00:00:00

abstract：:Induced sputum and bronchoalveolar lavage (BAL) are widely used for retrieving cells and soluble materials for studies of airway inflammation. Centrifuged cell samples are suitable for immunochemical identification of cellular products. The aim was to determine the optimal fixation procedure to detect intracellular an...

journal_title：Respiratory medicine

authors： Metso T,Haahtela T,Sevéus L

更新日期：2002-11-01 00:00:00

abstract：:Continuous positive airway pressure (CPAP) is the treatment of choice for obstructive sleep apnoea syndrome (OSAS), but many patients find this treatment intolerable. The aim of this study was to characterize patients who were unable to tolerate CPAP treatment (non-complaint) as opposed to those who continued using CP...

journal_title：Respiratory medicine

authors： Janson C,Nöges E,Svedberg-Randt S,Lindberg E

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:The need for additional research on symptomatic smokers with normal spirometry has been recently emphasized. Albeit not meeting criteria for Chronic obstructive pulmonary disease (COPD) diagnosis, symptomatic smokers may experience activity limitation, evidence of airway disease, and exacerbations. We, there...

journal_title：Respiratory medicine

authors： Di Marco F,Terraneo S,Job S,Rinaldo RF,Sferrazza Papa GF,Roggi MA,Santus P,Centanni S

更新日期：2017-06-01 00:00:00

abstract：INTRODUCTION:Older patients are the most prevalent age cohort requiring bronchoscopy. Prior sedation should be offered to improve patient comfort and operator technical ease. Older patients have increased sensitivity to centrally acting drugs increasing the procedural risk. This perceived risk may limit access to bronc...

journal_title：Respiratory medicine

authors： Watts MR,Geraghty R,Moore A,Saunders J,Swift CG

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:We have observed that Doctors often perceive that cystic fibrosis (CF) is exceptionally rare in non-whites, and that this bias has repeatedly resulted in diagnostic delay. We therefore compared the age at diagnosis, genetic features and relative prevalence of CF in non-whites and white patients in the West M...

journal_title：Respiratory medicine

authors： Spencer DA,Venkataraman M,Higgins S,Stevenson K,Weller PH

更新日期：1994-10-01 00:00:00

abstract：:In this study we aimed to estimate direct medical costs of Chronic Obstructive Pulmonary Disease (COPD) by disease type; chronic bronchitis and emphysema. This study estimates direct costs in 1996 dollars using a prevalence approach and both aggregate and microcosting. A societal perspective is taken using prevalence,...

journal_title：Respiratory medicine

authors： Wilson L,Devine EB,So K

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) is a common disease worldwide with significant morbidity and mortality. AIM:To investigate the effect of a comprehensive COPD management programme in decreasing COPD readmissions 1 year before and 1 year after the programme. METHOD:185 (166 males) patients admit...

journal_title：Respiratory medicine

authors： Ko FW,Ngai JC,Ng SS,Chan KP,Cheung R,Leung MY,Pun MC,Hui DS

更新日期：2014-12-01 00:00:00

abstract：AIM:Recent studies have shown that anti-Ro52 antibody is associated with both interstitial lung disease (ILD) and the degree of disease severity in juvenile patients with dermatomyositis (DM). We found that more than half of adult patients with DM were positive for anti-Ro52 antibody. In this study, we analysed the cor...

journal_title：Respiratory medicine

authors： Xing X,Li A,Li C

更新日期：2020-10-01 00:00:00

abstract：:The purpose of this randomized, double-blind parallel group study was to compare the safety, tolerability and acceptability of Easyhaler and Turbuhaler dry powder inhalers for the delivery of budesonide 800 microg day(-1) in adult asthmatic patients who had already been treated with inhaled corticosteroids for at leas...

journal_title：Respiratory medicine

authors： Tukiainen H,Rytilä P,Hämäläinen KM,Silvasti MS,Keski-Karhu J,Finnish Study Group.

更新日期：2002-04-01 00:00:00

abstract：:The prevalence of preferential nasal breathing was studied in an awake adult population. One hundred and ninety-four people consented to gentle manual compression of the nostrils. They were advised to 'breathe in and out', but no further information regarding breathing was given to avoid influencing the patient. One h...

journal_title：Respiratory medicine

authors： Ward KA,Nicholls DP,Stanford CF

更新日期：1993-05-01 00:00:00

abstract：:The ability of immunotherapy with heat-killed Mycobacterium vaccae (NCTC 11659), as an addition to the available chemotherapy, to improve the outcome in patients with multi-drug-resistant tubercle bacilli (MDRTB) who had not been cured by chemotherapy alone was evaluated in tuberculosis centres in Estonia, Iran, Kuwai...

journal_title：Respiratory medicine

authors： Stanford JL,Stanford CA,Grange JM,Lan NN,Etemadi A

更新日期：2001-06-01 00:00:00

abstract：:The present study investigated, for the first time, the long-term prognosis of hypersensitivity type of occupational laryngitis (OL). Thirteen patients with OL diagnosed in 1990-1993 at the Finnish Institute of Occupational Health participated in a questionnaire follow-up study. The records of the primary diagnostic i...

journal_title：Respiratory medicine

authors： Hannu T,Sala E,Toskala E

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Although the utility of blind biopsy in the detection of metastasis in the carina has been reported, submucosal fine needle aspiration (SMFNA) has not been evaluated. We investigated how SMFNA of the main carina and upper-lobe carina in addition to blind biopsy affect management of patients with NSCLC. METH...

journal_title：Respiratory medicine

authors： Kaynar H,Meral M,Ucar EY,Saglam L,Yildirim U,Gorguner M,Akgun M

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND AND AIMS:The total serum IgE level is a marker of immunological activity in allergic bronchopulmonary aspergillosis (ABPA), and a 35% decline beyond six weeks is traditionally taken as criteria for remission. The aim of this study was to evaluate the magnitude and clinical significance of decline in serum Ig...

journal_title：Respiratory medicine

authors： Agarwal R,Gupta D,Aggarwal AN,Saxena AK,Saikia B,Chakrabarti A,Jindal SK

更新日期：2010-02-01 00:00:00

abstract：:Seven patients with fibrosing alveolitis who failed to respond to prednisolone and cyclophosphamide and were deteriorating, were treated with cyclosporin A. An initial favourable response was seen but was not maintained. When compared to a control population, matched for the extremely severe disease present in the tre...

journal_title：Respiratory medicine

authors： Alton EW,Johnson M,Turner-Warwick M

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:Video-assisted thoracoscopic surgery (VATS) is now the generally preferred surgical treatment for spontaneous pneumothorax but is more difficult once pleural adhesions have developed. To test the hypothesis that VATS is under-used because of prolonged pleural intubation, we have audited the effect of preoper...

journal_title：Respiratory medicine

authors： Waller DA,McConnell SA,Rajesh PB

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:Obstructive sleep apnea (OSA) is emerging as a significant disorder in India. Tumor necrosis factor-alpha (TNFalpha) is an important marker of inflammation. Recent data indicate that inflammation may be an important correlate of OSA. The relationships of OSA with TNFalpha levels and TNFalpha gene promoter po...

journal_title：Respiratory medicine

authors： Bhushan B,Guleria R,Misra A,Luthra K,Vikram NK

更新日期：2009-03-01 00:00:00