Serum cytokine profiles of patients with interstitial lung disease associated with anti-CADM-140/MDA5 antibody positive amyopathic dermatomyositis.

abstract：BACKGROUND:Limited data are available as to the relationship between computed tomography (CT) derived data on emphysema and airway wall thickness, and quality of life in subjects with chronic obstructive pulmonary disease (COPD). Such data may work to clarify the clinical correlate of the CT findings. METHODS:We inclu...

journal_title：Respiratory medicine

authors： Gietema HA,Edwards LD,Coxson HO,Bakke PS,ECLIPSE Investigators.

更新日期：2013-08-01 00:00:00

abstract：:The HandiHaler is a novel breath-actuated dry powder system designed for the delivery of tiotropium 18microg daily in the treatment of COPD. We compared patient ability to use the HandiHaler or metered dose inhaler (MDI) device correctly 4 weeks after receiving brief instructions and device demonstration. A single-bli...

journal_title：Respiratory medicine

authors： Dahl R,Backer V,Ollgaard B,Gerken F,Kesten S

更新日期：2003-10-01 00:00:00

abstract：:The role of positive end-expiratory pressure (PEEP) in the postoperative course of cardiac surgery patients remains questionable. In this prospective study, we examined the effect of different levels of PEEP on arterial oxygenation, SvO2 and PvO2 values, and on haemodynamic indices, during the early postoperative peri...

journal_title：Respiratory medicine

authors： Michalopoulos A,Anthi A,Rellos K,Geroulanos S

更新日期：1998-06-01 00:00:00

abstract：:Malnutrition may be an extremely important complicating factor in patients with a variety of chronic lung diseases. The impact of malnutrition on lung disease and respiratory muscle function has been extensively studied in patients with chronic lung disease due to cystic fibrosis (CF). In patients with CF it appears t...

journal_title：Respiratory medicine

authors： Heijerman HG

更新日期：1993-08-01 00:00:00

abstract：OBJECTIVES:To analyze the conditions of psychological dysfunction and positive mental health in patients with asthma and chronic bronchitis (CB), as compared to healthy individuals, and to identify the factors associated with these mental health indicators. METHODS:Cross-sectional study based on data obtained from the...

journal_title：Respiratory medicine

authors： de Miguel Diez J,García RJ,Hernandez Barrera V,Rodríguez PR,Maestu LP,Garrido PC

更新日期：2012-07-01 00:00:00

abstract：INTRODUCTION:The discrepancy rates of drug susceptibility testing (DST) results between solid and liquid media have been reported to range from 2.4 to 7.4% for isoniazid. Most isolate with isoniazid DST discrepancies between solid and liquid media test as susceptible on solid medium and resistant in liquid medium, howe...

journal_title：Respiratory medicine

authors： Kim S,Lee H,Park HY,Jeon K,Huh HJ,Lee NY,Jeong BH

更新日期：2017-12-01 00:00:00

abstract：:The objective of this study was to describe asthma exacerbation self-management in children and adolescents. We used a cross-sectional study population enrolled in the International Study of Asthma and Allergies in Childhood (ISAAC) in Bordeaux. Subjects answered an additional questionnaire on utilization of health se...

journal_title：Respiratory medicine

authors： Raherison C,Tunon-de-Lara JM,Vernejoux JM,Taytard A

更新日期：2000-11-01 00:00:00

abstract：INTRODUCTION:Subjective fatigue has been recognised as an important, multi-component symptom in COPD. Pulmonary Rehabilitation (PR) improves fatigue component of the Chronic Respiratory Questionnaire, a quality of life (QoL) measure. However, it is not clear if all fatigue dimensions are affected equally. This study ai...

journal_title：Respiratory medicine

authors： Lewko A,Bidgood PL,Jewell A,Garrod R

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVES:To compare the prognostic value of FENO with bronchoprovocation testing when the clinical course within the first year after assessment was taken into account; to compare the prognostic values with respect to eosinophilic versus non-eosinophilic inflammatory pattern. METHODS:Cross-sectional diagnostic study...

journal_title：Respiratory medicine

authors： Schneider A,Faderl B,Schwarzbach J,Welker L,Karsch-Völk M,Jörres RA

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Idiopathic pulmonary fibrosis (IPF) is a progressive and irreversible interstitial lung disease with poor prognosis despite the recent availability of two antifibrotic drugs. Patients are more susceptible to cardiovascular comorbidities. In this study, we aimed to determine the impact of concom...

journal_title：Respiratory medicine

authors： M Lambert E,A Wuyts W,Yserbyt J,De Sadeleer LJ

更新日期：2020-11-26 00:00:00

abstract：:Metered dose inhalers (MDIs) are the mainstay of inhaled steroid therapy for asthma. With the phasing out of traditional chlorofluorocarbon (CFC) propellants and their replacement with a new generation of CFC-free products, it is becoming clear that formulation and inhaler characteristics can markedly affect the drug ...

journal_title：Respiratory medicine

authors： Shaw RJ

更新日期：1999-03-01 00:00:00

abstract：:The 72 kDa matrix metalloproteinase (MMP-2) and the 92 kDa matrix metalloproteinase (MMP-9), are type IV collagenases that have been implicated as important factors in cancer invasion and metastasis formation. We have used quantitative zymography and computer-assisted image analysis to measure the levels of MMP-9 and ...

journal_title：Respiratory medicine

authors： Hrabec E,Strek M,Nowak D,Hrabec Z

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Patients with chronic obstructive pulmonary disease (COPD) are responsible for a high utilisation of the health care resources, and the cost is expected to increase. Physiological measures of lung function often fail to describe the impact the symptoms have on exacerbations, days of hospitalisation, and on a...

journal_title：Respiratory medicine

authors： Emtner MI,Arnardottir HR,Hallin R,Lindberg E,Janson C

更新日期：2007-05-01 00:00:00

abstract：:The need for efficient use of resources in the provision of health care is now an accepted reality. Despite its economic significance, respiratory disease has been the subject of very few examples of the application of techniques of economic evaluation. There are a number of examples of cost-minimization studies, and ...

journal_title：Respiratory medicine

authors： Buxton MJ

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:An ongoing outbreak of coronavirus disease 2019 (COVID-19) has spread around the world. It is debatable whether asymptomatic COVID-19 virus carriers are contagious. We report here a case of the asymptomatic patient and present clinical characteristics of 455 contacts, which aims to study the infectivity of a...

journal_title：Respiratory medicine

authors： Gao M,Yang L,Chen X,Deng Y,Yang S,Xu H,Chen Z,Gao X

更新日期：2020-08-01 00:00:00

abstract：:Assessment of asthma severity is important for disease management. Analysis of symptoms past and present, and previous and actual lung function measurements (including variability) is the usual method of evaluation and classification of asthma disease severity and activity. However, symptoms and lung function alterati...

journal_title：Respiratory medicine

authors： Dahl R,Martinati LC,Boner AL

更新日期：1997-11-01 00:00:00

abstract：:The effect of patient education on morbidity in asthmatics and COPD patients has not previously been investigated in a single study. We randomized 78 asthmatics and 62 COPD patients after ordinary outpatient management. Intervention consisted of educational group sessions and individual sessions administered by a trai...

journal_title：Respiratory medicine

authors： Gallefoss F,Bakke PS

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Although the utility of blind biopsy in the detection of metastasis in the carina has been reported, submucosal fine needle aspiration (SMFNA) has not been evaluated. We investigated how SMFNA of the main carina and upper-lobe carina in addition to blind biopsy affect management of patients with NSCLC. METH...

journal_title：Respiratory medicine

authors： Kaynar H,Meral M,Ucar EY,Saglam L,Yildirim U,Gorguner M,Akgun M

更新日期：2011-10-01 00:00:00

abstract：:In an attempt to guide physicians asked by respiratory patients for advice on flight fitness, the British Thoracic Society (BTS) have published guidelines on fitness to fly. The main potential hazard is hypobaric hypoxia, and efforts have focused on the prediction of hypoxia in individuals. The present study examines ...

journal_title：Respiratory medicine

authors： Robson AG,Lenney J,Innes JA

更新日期：2008-11-01 00:00:00

abstract：:The ability of immunotherapy with heat-killed Mycobacterium vaccae (NCTC 11659), as an addition to the available chemotherapy, to improve the outcome in patients with multi-drug-resistant tubercle bacilli (MDRTB) who had not been cured by chemotherapy alone was evaluated in tuberculosis centres in Estonia, Iran, Kuwai...

journal_title：Respiratory medicine

authors： Stanford JL,Stanford CA,Grange JM,Lan NN,Etemadi A

更新日期：2001-06-01 00:00:00

abstract：:Smoking and body mass index (BMI) are well-documented risk factors that contribute substantially to chronic obstructive pulmonary disease (COPD) and asthma. However, the relations among smoking, obesity, and COPD or asthma remain to be clarified. We conducted a population-based cross-sectional epidemiologic study to e...

journal_title：Respiratory medicine

authors： Cazzola M,Calzetta L,Lauro D,Bettoncelli G,Cricelli C,Di Daniele N,Rogliani P

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:It has been shown that interleukin (IL)-18 levels in induced sputum are reduced in asthmatic and healthy smokers. However, in chronic obstructive pulmonary disease (COPD) patients, recent data show an overproduction in the lungs and increased serum levels of IL-18, suggesting that IL-18 may be involved in th...

journal_title：Respiratory medicine

authors： Rovina N,Dima E,Gerassimou C,Kollintza A,Gratziou C,Roussos C

更新日期：2009-07-01 00:00:00

abstract：STUDY OBJECTIVES:To test if morbid obesity causes pulmonary function changes and if massive weight loss have effect on pulmonary function (especially in subjects with BMI>or=60 kg/m(2)). PARTICIPANTS:Thirty-nine morbid obese subjects before and after massive weight loss. MEASUREMENTS AND RESULTS:Patients had baseline...

journal_title：Respiratory medicine

authors： Santana AN,Souza R,Martins AP,Macedo F,Rascovski A,Salge JM

更新日期：2006-06-01 00:00:00

abstract：:A survey was conducted in a metropolitan suburb to examine family clusters of pulmonary tuberculosis patients and related factors. Firstly, a descriptive study was done based on the review of tuberculosis registration cards over a 11-yr period. Of 1106 cases, 109 (9.9%) were found to occur in households which had alre...

journal_title：Respiratory medicine

authors： Kondo T,Hotta I,Yamanaka K,Sakakibara H,Miyao M,Yamada S

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:Previous investigations have suggested that genetic variations are associated with reduced lung function in early childhood. This study was conducted to evaluate the association between IL13+2044G-->A, the functionally relevant single nucleotide polymorphism (SNP) in the gene coding IL13, and lung function i...

journal_title：Respiratory medicine

authors： Park HW,Lee JE,Kim SH,Kim YK,Min KU,Kim YY,Cho SH

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Pulmonary rehabilitation is very effective in improving exercise capacity, dyspnea and quality of life in the small group of patients with moderate to severe COPD. Given that little is known about exercise training in the large group of patients with mild to moderate COPD, we assessed the effectiveness of an...

journal_title：Respiratory medicine

authors： Fastenau A,van Schayck OC,Winkens B,Aretz K,Gosselink R,Muris JW

更新日期：2020-01-01 00:00:00

abstract：INTRODUCTION:Multiple Breath Washout (MBW) to measure Lung Clearance Index (LCI) is increasingly being used as a secondary endpoint in multicentre bronchiectasis studies. LCI data quality control or "over-reading" is resource intensive and the impact is unclear. OBJECTIVES:To assess the proportion of MBW tests deemed ...

journal_title：Respiratory medicine

authors： O'Neill K,Lakshmipathy GR,Ferguson K,Cosgrove D,Hill AT,Loebinger MR,Carroll M,Chalmers JD,Gatheral T,Johnson C,DeSoyza A,Hurst JR,Bradbury I,Elborn JS,Bradley JM

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Asthma in the elderly as well as asthma of adult-onset has been associated with increased morbidity, but little is known specifically about the effects of age on clinical and inflammatory outcomes in severe refractory asthma. The aims of the study were to examine the effects of age [<65 versus ≥65 years] and...

journal_title：Respiratory medicine

authors： Chaudhuri R,McSharry C,Heaney LG,Niven R,Brightling CE,Menzies-Gow AN,Bucknall C,Mansur AH,Lee W,Shepherd M,Spears M,Cowan DC,Husi H,Thomson NC,BTS Severe Asthma Network.

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Decreased lung function has health impacts beyond diagnosable lung disease. It is therefore important to understand the factors that may influence even small changes in lung function including obesity, physical fitness and physical activity. The aim of this study was to determine the anthropometric measure m...

journal_title：Respiratory medicine

authors： Rowe A,Hernandez P,Kuhle S,Kirkland S

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Cystic fibrosis affects 1/3200 Caucasians. This genetic disease disturbs the ion and water homeostasis across epithelia, thus rendering mucus more viscous and harder to expel. Conventional treatments rely on the clapping method coupled with postural drainage. Despite the effectiveness of these procedures, th...

journal_title：Respiratory medicine

authors： Schieppati D,Germon R,Galli F,Rigamonti MG,Stucchi M,Boffito DC

更新日期：2019-07-01 00:00:00