Abstract:
BACKGROUND:Patients with chronic obstructive pulmonary disease (COPD) are responsible for a high utilisation of the health care resources, and the cost is expected to increase. Physiological measures of lung function often fail to describe the impact the symptoms have on exacerbations, days of hospitalisation, and on a patient's health. METHODS:Twenty-one patients (14 female) with COPD (65 years, 40-79 years) admitted to the Department of Respiratory Medicine in Uppsala, performed a pulmonary function test (FEV(1)% predicted=37) and health status measurement (St. Georges Respiratory Questionnaire, SGRQ) at discharge. Four to six weeks after discharge, when they were in a stable clinical condition, they performed an exercise test (Incremental Shuttle Walk Test, ISWT) to measure their exercise capacity. RESULTS:Nine of 21 patients (43%) were rehospitalised within 12 month. The mean distance walked in the ISWT was 174m in patients who were hospitalised and 358m in non-hospitalised patients (P<0.001). Oxygen saturation 88% after the ISWT was found in 73% of hospitalised patients in contrast to only 22% in non-hospitalised patients (P<0.05). Activity related health status (SGRQ-activity) was higher (worse) in hospitalised patients than in non-hospitalised patients (75 vs. 50) (P<0.05). The association between walking distance and the risk of rehospitalisation was significant after adjusting for oxygen saturation and health status (hazard risk ratio 0.8 (0.67-0.97) per 10m). This study has shown that walking distance is a good and reliable predictor of rehospitalisations in moderately and severely disabled patients with COPD.
journal_name
Respir Medjournal_title
Respiratory medicineauthors
Emtner MI,Arnardottir HR,Hallin R,Lindberg E,Janson Cdoi
10.1016/j.rmed.2006.09.020subject
Has Abstractpub_date
2007-05-01 00:00:00pages
1037-40issue
5eissn
0954-6111issn
1532-3064pii
S0954-6111(06)00491-4journal_volume
101pub_type
杂志文章abstract::Fifty-four members of two families were studied, nine of whom had familial spontaneous pneumothorax. The disease was inherited by autosomal-dominant type, with incomplete penetration and (or) variable expression. Five patients underwent bullectomy and parietal pleurectomy simultaneously on both sides via median sterno...
journal_title:Respiratory medicine
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journal_title:Respiratory medicine
pub_type: 杂志文章,评审
doi:
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pub_type: 杂志文章,meta分析
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pub_type: 杂志文章
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更新日期:1991-09-01 00:00:00
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pub_type: 杂志文章
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doi:10.1016/j.rmed.2007.02.002
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pub_type: 杂志文章,meta分析
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pub_type: 杂志文章
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更新日期:2018-09-01 00:00:00
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doi:10.1016/j.rmed.2017.04.006
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pub_type: 杂志文章
doi:10.1016/s0954-6111(99)90010-0
更新日期:1999-03-01 00:00:00
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pub_type: 杂志文章
doi:10.1053/rmed.2001.1116
更新日期:2001-08-01 00:00:00
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journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/s0954-6111(06)80104-6
更新日期:1991-07-01 00:00:00
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pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1996-09-01 00:00:00
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pub_type: 杂志文章,评审
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pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Respiratory medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.rmed.2005.12.001
更新日期:2006-09-01 00:00:00
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pub_type: 杂志文章
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更新日期:2007-01-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.1016/j.rmed.2008.07.015
更新日期:2009-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2017-11-01 00:00:00
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journal_title:Respiratory medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.rmed.2014.10.005
更新日期:2014-12-01 00:00:00
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pub_type: 杂志文章
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更新日期:2015-03-01 00:00:00