COPD care programme can reduce readmissions and in-patient bed days.

abstract：:Weight loss has been recognized as a feature of advanced emphysema and a factor of poor prognosis, but its mechanisms remain obscure. Studies have demonstrated high serum concentrations of TNF-a (cachexin) in chronic obstructive pulmonary disease (COPD) patients with emphysema. Pink puffers (PP) COPD patients have wor...

journal_title：Respiratory medicine

authors： Pitsiou G,Kyriazis G,Hatzizisi O,Argyropoulou P,Mavrofridis E,Patakas D

更新日期：2002-08-01 00:00:00

abstract：:This retrospective study reviews the patterns of P. cepacia pulmonary infection in 75 of a total of 872 mainly adults with cystic fibrosis, registered here during the 4 years 1987-1990; 35 (47%) were female. During this period, 55 patients acquired P. cepacia and the annual incidence and prevalence rates have remained...

journal_title：Respiratory medicine

authors： Taylor RF,Gaya H,Hodson ME

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:Systemic inflammation is associated with impaired lung function in healthy adults as well as in patients with lung disease. The mechanism for this association is unknown and it is unclear if systemic inflammation leads to impaired lung function or if poor lung function leads to inflammation. We explored the ...

journal_title：Respiratory medicine

authors： Hancox RJ,Gray AR,Sears MR,Poulton R

更新日期：2016-02-01 00:00:00

abstract：:Asthma progression is associated with airway remodeling and neo-vascularization. However, role of angiogenesis in these changes remains unclear and available data still incomplete. In this pilot study we verify usefulness of proteome profiler assay in screening of angiogenesis-related factors in exhaled breath condens...

journal_title：Respiratory medicine

authors： Grzela K,Litwiniuk M,Krejner A,Zagorska W,Grzela T

更新日期：2016-09-01 00:00:00

abstract：:Cyclosporin A (CsA) is an immunomodulator drug that has been used in the treatment of several types of advanced pulmonary interstitial disease. This beneficial effect occurs mainly in circumstances in which alveolitis due to CD4 lymphocytes is absent, suggesting that CsA acts on other types of cells. The present study...

journal_title：Respiratory medicine

authors： Losa García JE,Mateos Rodríguez F,Jiménez López A,García Salgado MJ,Martín de Cabo MR,Pérez Losada J,Pérez Arellano JL

更新日期：1998-05-01 00:00:00

abstract：:The role of positive end-expiratory pressure (PEEP) in the postoperative course of cardiac surgery patients remains questionable. In this prospective study, we examined the effect of different levels of PEEP on arterial oxygenation, SvO2 and PvO2 values, and on haemodynamic indices, during the early postoperative peri...

journal_title：Respiratory medicine

authors： Michalopoulos A,Anthi A,Rellos K,Geroulanos S

更新日期：1998-06-01 00:00:00

abstract：:Chlorofluorocarbon (CFC)-containing inhalers for use in the treatment of asthma are to be phased out under the terms of the Montreal Protocol (1). In this multi-centre, randomized, double-blind study, the therapeutic equivalence of two formulations of beclomethasone dipropionate (BDP) containing CFC or non-CFC (HFA134...

journal_title：Respiratory medicine

authors： Farmer IS,Middle M,Savic J,Perri VL,Herdman MJ

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Nitrite in exhaled breath condensate (EBC) has been shown to be elevated in cystic fibrosis (CF), while exhaled nitric oxide (FENO) is paradoxically low. This has been argued to reflect increased metabolism of NO while its diffusion is obstructed by mucus. However, we wanted to study the possible influence o...

journal_title：Respiratory medicine

authors： Zetterquist W,Marteus H,Kalm-Stephens P,Näs E,Nordvall L,Johannesson M,Alving K

更新日期：2009-02-01 00:00:00

abstract：:Asthma is a very common respiratory disease which is characterized by the presence of cytokine-mediated airway inflammation leading to smooth muscle contraction, oedema and progressive airway damage in some cases. In light of our recent finding of an increased sero-prevalence of Helicobacter pylori in bronchiectasis, ...

journal_title：Respiratory medicine

authors： Tsang KW,Lam WK,Chan KN,Hu W,Wu A,Kwok E,Zheng L,Wong BC,Lam SK

更新日期：2000-08-01 00:00:00

abstract：:Although the principles of asthma management are well established in Europe, the available data indicate that asthma in patients is not well controlled. Many patients derive incomplete benefit from their inhaled medication because they do not use inhaler devices correctly and this may compromise asthma control. The Ae...

journal_title：Respiratory medicine

authors： Crompton GK,Barnes PJ,Broeders M,Corrigan C,Corbetta L,Dekhuijzen R,Dubus JC,Magnan A,Massone F,Sanchis J,Viejo JL,Voshaar T,Aerosol Drug Management Improvement Team.

更新日期：2006-09-01 00:00:00

abstract：INTRODUCTION:There are insufficient data on the treatment of latent tuberculosis infection (LTBI) in elderly patients. We investigated the completion rate of treatment in elderly LTBI patients. METHODS:A retrospective multicentre study was conducted at five university hospitals in South Korea. We reviewed the electron...

journal_title：Respiratory medicine

authors： Noh CS,Kim HI,Choi H,Kim Y,Kim CH,Choi JH,Hyun IG,Baek MS

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Fluticasone propionate and formoterol fumarate have been combined in a single inhaler (fluticasone/formoterol; flutiform(®)) for the maintenance treatment of asthma. This pooled analysis assessed the efficacy of fluticasone/formoterol versus fluticasone in patients who previously received inhaled corticoster...

journal_title：Respiratory medicine

authors： Papi A,Price D,Sastre J,Kaiser K,Lomax M,McIver T,Dissanayake S

更新日期：2015-02-01 00:00:00

abstract：:Given the high prevalence of chronic obstructive pulmonary disease (COPD), the impact of exacerbations on quality of life, and the costs incurred, effective ways for the prevention of exacerbations, and for reductions in the severity and duration of COPD symptoms are needed. Bacterial immunostimulation has been advoca...

journal_title：Respiratory medicine

authors： Cazzola M,Rogliani P,Curradi G

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:In COPD patients, hyperinflation impairs cardiac function. We examined whether lung deflation improves oxygen pulse, a surrogate marker of stroke volume. METHODS:In 129 NETT patients with cardiopulmonary exercise testing (CPET) and arterial blood gases (ABG substudy), hyperinflation was assessed with residu...

journal_title：Respiratory medicine

authors： Come CE,Divo MJ,San José Estépar R,Sciurba FC,Criner GJ,Marchetti N,Scharf SM,Mosenifar Z,Make BJ,Keller CA,Minai OA,Martinez FJ,Han MK,Reilly JJ,Celli BR,Washko GR,NETT Research Group.

更新日期：2012-01-01 00:00:00

abstract：:Patients with COPD are at risk for other comorbid diseases, like heart failure, coronary heart disease, and depression. However, little is known about COPD phenotypes and prevalence of sub-clinical renal failure. 433 COPD patients and 233 subjects without COPD, from Western Norway, age 40-75, GOLD stage II-IV, were ex...

journal_title：Respiratory medicine

authors： Gjerde B,Bakke PS,Ueland T,Hardie JA,Eagan TM

更新日期：2012-03-01 00:00:00

abstract：:The records of a total of 497 patients notified to have active tuberculosis (TB) in Western Australia from 1986 to 1990 inclusive have been reviewed in relation to case-finding. Of these, 276 (55.5%) were Asian migrants, 92 (18.5%) Europeans and 110 (22.1%) Australians. The disease was confirmed bacteriologically in 2...

journal_title：Respiratory medicine

authors： Pang SC,Harrison RH,Clayton AS,Mercer J,Brearley J

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND:The histologic diagnosis of Pulmonary Langerhans cell histiocytosis (PLCH) is invasive and can cause complications. To confirm the diagnosis of PLCH, guidelines therefore recommend measuring CD1a-positive bronchoalveolar lavage fluid (BALF) cells despite its poor sensitivity and specificity. Thus, an improve...

journal_title：Respiratory medicine

authors： Lommatzsch M,Bratke K,Stoll P,Mülleneisen N,Prall F,Bier A,Virchow JC

更新日期：2016-10-01 00:00:00

abstract：:Gastroesophageal reflux (GER) may induce respiratory symptoms (RS) through inhalation of acid gastric contents. To characterize the airway inflammation associated with this condition, 20 children [7.4 (0.9) yr old] with "difficult to treat" RS and a positive 24-h oesophageal pH monitoring (pHm) were studied and bronch...

journal_title：Respiratory medicine

authors： Sacco O,Silvestri M,Sabatini F,Sale R,Moscato G,Pignatti P,Mattioli G,Rossi GA

更新日期：2006-02-01 00:00:00

abstract：INTRODUCTION:Non-cystic fibrosis(CF) bronchiectasis has been recognized in children for the past 200 years. Early childhood pneumonia and underlying conditions such as immunodeficiency, primary ciliary dyskinesia(PCD), and congenital lung pathology should be considered in the etiology. The aim of our study was to descr...

journal_title：Respiratory medicine

authors： Satırer O,Mete Yesil A,Emiralioglu N,Tugcu GD,Yalcın E,Dogru D,Kiper N,Ozcelik U

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Susceptibility to Chronic Obstructive Pulmonary Disease (COPD) has a genetic component. We undertook a study to determine if a genetic variant of the gene encoding the cyclooxygenase-2 gene influences the likelihood of developing COPD. METHODS:In a case control study the frequency of a single nucleotide pol...

journal_title：Respiratory medicine

authors： Wu L,Merrilees M,Young RP,Black PN

更新日期：2011-03-01 00:00:00

abstract：:Invasive pulmonary aspergillosis is a frequent complication in immunocompromised patients. The role of the prolonged use of steroids in predisposing to invasive aspergillosis has been recognized, but exceptionally described in asthmatic patients. We report the case of a 59-year-old woman with bronchial asthma treated ...

journal_title：Respiratory medicine

authors： Ganassini A,Cazzadori A

更新日期：1995-02-01 00:00:00

abstract：BACKGROUND:An Expert Forum was held at the 2014 European Respiratory Society International Congress to address issues involved in the management of Pseudomonas aeruginosa infection in patients with non-cystic fibrosis bronchiectasis (NCFB). Multiple studies have found that chronic P. aeruginosa infection is associated ...

journal_title：Respiratory medicine

authors： Wilson R,Aksamit T,Aliberti S,De Soyza A,Elborn JS,Goeminne P,Hill AT,Menendez R,Polverino E

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Familial dysautonomia (Riley-Day syndrome, hereditary sensory autonomic neuropathy type-III) is a rare genetic disease caused by impaired development of sensory and afferent autonomic nerves. As a consequence, patients develop neurogenic dysphagia with frequent aspiration, chronic lung disease, and chemorefl...

journal_title：Respiratory medicine

authors： Kazachkov M,Palma JA,Norcliffe-Kaufmann L,Bar-Aluma BE,Spalink CL,Barnes EP,Amoroso NE,Balou SM,Bess S,Chopra A,Condos R,Efrati O,Fitzgerald K,Fridman D,Goldenberg RM,Goldhaber A,Kaufman DA,Kothare SV,Levine J,Levy

更新日期：2018-08-01 00:00:00

abstract：:Smoking and body mass index (BMI) are well-documented risk factors that contribute substantially to chronic obstructive pulmonary disease (COPD) and asthma. However, the relations among smoking, obesity, and COPD or asthma remain to be clarified. We conducted a population-based cross-sectional epidemiologic study to e...

journal_title：Respiratory medicine

authors： Cazzola M,Calzetta L,Lauro D,Bettoncelli G,Cricelli C,Di Daniele N,Rogliani P

更新日期：2013-09-01 00:00:00

abstract：:There is no agreement on the minimum absolute eosinophil count essential for the diagnosis of tropical pulmonary eosinophilia (TPE) at present. The aim of this study was to determine this figure as well as to evaluate the other diagnostic criteria of TPE. The response to diethylcarbamazine (DEC) was tested in 98 patie...

journal_title：Respiratory medicine

authors： Cooray JH,Ismail MM

更新日期：1999-09-01 00:00:00

abstract：:Hypoxemic patients with chronic obstructive pulmonary disease (COPD) are at risk of carbon dioxide (CO(2)) retention during oxygen therapy and hypercapnia in COPD is associated with an ominous prognosis. Rebreathing with oxygen mask is possible in practice and possibly affects CO(2) retention due to an increased inspi...

journal_title：Respiratory medicine

authors： Fremault A,Silva M,Beaucage F,Berckmans D,Decramer M

更新日期：2008-12-01 00:00:00

abstract：:Lung cancer remains the most common cause of cancer-related mortality in Scotland, accounting for 28.9% of all cancer deaths in 2007. (1) Current guidelines recommend assessment of patient fitness and operability by a multi-disciplinary team when selecting management options. (2-6) Two of the most important prognostic...

journal_title：Respiratory medicine

authors： Tsim S,O'Dowd CA,Milroy R,Davidson S

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Posturally induced changes in minute ventilation in patients may be autonomically driven. This study aimed to test whether changes in autonomic tone with posture differed between normal and asthmatic subjects and whether this related to changes in indices of ventilation. METHODS:Ten patients with type 1 bri...

journal_title：Respiratory medicine

authors： Mukhopadhyay J,Bates R,Manney S,Ayres JG

更新日期：2007-05-01 00:00:00

abstract：INTRODUCTION:Older patients are the most prevalent age cohort requiring bronchoscopy. Prior sedation should be offered to improve patient comfort and operator technical ease. Older patients have increased sensitivity to centrally acting drugs increasing the procedural risk. This perceived risk may limit access to bronc...

journal_title：Respiratory medicine

authors： Watts MR,Geraghty R,Moore A,Saunders J,Swift CG

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:SLS COPD was the first open-label randomised controlled trial demonstrating a reduction in moderate/severe COPD exacerbations with once-daily inhaled fluticasone furoate/vilanterol (FF/VI) in everyday clinical practice. Here we report FF/VI effectiveness and safety in predefined patient subgroups. METHODS:P...

journal_title：Respiratory medicine

authors： Bakerly ND,Woodcock A,Collier S,Leather DA,New JP,Crawford J,Harvey C,Vestbo J,Boucot I

更新日期：2019-02-01 00:00:00