Influence of salmeterol/fluticasone via single versus separate inhalers on exacerbations in severe/very severe COPD.

abstract：:Fifty-four members of two families were studied, nine of whom had familial spontaneous pneumothorax. The disease was inherited by autosomal-dominant type, with incomplete penetration and (or) variable expression. Five patients underwent bullectomy and parietal pleurectomy simultaneously on both sides via median sterno...

journal_title：Respiratory medicine

authors： Nickoladze GD

更新日期：1990-03-01 00:00:00

abstract：:Abnormal heart rate recovery (HRR) after exercise, a marker of cardiac autonomic dysfunction, is associated with poor prognosis in various populations. As chronic obstructive pulmonary disease (COPD) is associated with cardiac autonomic dysfunction, we tested the hypothesis that patients with COPD have a lower HRR tha...

journal_title：Respiratory medicine

authors： Lacasse M,Maltais F,Poirier P,Lacasse Y,Marquis K,Jobin J,LeBlanc P

更新日期：2005-07-01 00:00:00

abstract：:The aim of the study was to investigate which features predict favourable response to omeprazole therapy in asthmatics with gastro-oesophageal reflux (GER). The study population consisted of 52 outpatient asthmatics with GER who had completed an intervention where they were randomized to receive omeprazole 40 mg once ...

journal_title：Respiratory medicine

authors： Kiljander T,Salomaa ER,Hietanen E,Helenius H,Liippo K,Terho EO

更新日期：2001-05-01 00:00:00

abstract：:Seventy-seven patients with morbid obesity, body mass index (BMI) 40-69.9 kg m(-2), who were candidates for gastroplasty, were studied in our laboratory as part of a pre-operative survey. They had no complaints other than obesity and were not cyanotic. A group of 28 lean subjects (BMI 20-29.8 kg m(-2)) who were candid...

journal_title：Respiratory medicine

authors： Ladosky W,Botelho MA,Albuquerque JP Jr

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:There are limited data on the role of adipokines in atopic asthma. AIM:To determine serum level of apelin-12 (APE-12) in asthmatic children in relation to BMI and gender. METHODS:Serum APE-12 levels were measured using ELISA in 89 asthmatic children (61 boys and 28 girls, aged 7.0-17.0 years) and in 33 hea...

journal_title：Respiratory medicine

authors： Machura E,Ziora K,Ziora D,Swiętochowska E,Krakowczyk H,Halkiewicz F,Kasperska-Zajac A

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Exercise induced asthma may symptomatically be difficult to differentiate from exercise related obstruction in the upper airways, sometimes leading to diagnostic confusion and inappropriate treatment. Larynx accounts for a significant fraction of total airway resistance, but its role as a limiting factor for...

journal_title：Respiratory medicine

authors： Røksund OD,Maat RC,Heimdal JH,Olofsson J,Skadberg BT,Halvorsen T

更新日期：2009-12-01 00:00:00

abstract：INTRODUCTION:Up to 40% of patients seen in a cough clinic have unexplained chronic cough. The long term outcome of these patients is uncertain. OBJECTIVE:To determine the long-term outcome in patients diagnosed with unexplained chronic cough. METHODS:We have performed a longitudinal study of symptoms, airway inflamma...

journal_title：Respiratory medicine

authors： Yousaf N,Montinero W,Birring SS,Pavord ID

更新日期：2013-03-01 00:00:00

abstract：:Inhalation therapy is the mainstay of chronic obstructive pulmonary disease management, and inhaler selection can have a profound impact on drug delivery and medication adherence, as well as on treatment outcomes. Although multiple delivery systems, such as pressurized metered-dose inhalers, dry powder inhalers, slow-...

journal_title：Respiratory medicine

authors： Mahler DA

更新日期：2020-01-01 00:00:00

abstract：:Increased levels of exhaled nitric oxide (FeNO) and airway hyperresponsiveness (AHR) to inhaled mannitol are related to allergic inflammation characterized by eosinophil infiltration and a clinical response to treatment with anti-inflammatory agents in subjects with asthma. This study determines the diagnostic accurac...

journal_title：Respiratory medicine

authors： Sverrild A,Malinovschi A,Porsbjerg C,Backer V,Alving K

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Holding chambers or spacers can enhance the efficacy of pressurized metered dose inhalers (pMDI) in delivering inhaled medications, as they reduce the need for hand-breath coordination and improve lower airways deposition. Nevertheless, their cost can be high for patients in low-income countries. OBJECTIVE:...

journal_title：Respiratory medicine

authors： Schor D,Rizzo JÂ,Medeiros D,Dela Bianca AC,Silva AR,Nunes C,Morais-Almeida M,Sarinho E

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Recent studies have shown strong evidence that bronchiolitis obliterans is the major long-term sequelae of exposure to sulfur mustard (SM). This study is the first to examine the histopathologic spectrum of changes in a large number of surgical lung biopsies from patients exposed to SM. METHOD:Fifteen patie...

journal_title：Respiratory medicine

authors： Ghanei M,Tazelaar HD,Chilosi M,Harandi AA,Peyman M,Akbari HM,Shamsaei H,Bahadori M,Aslani J,Mohammadi A

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:We hypothesized that the peculiar mixed interleukin-4 (IL-4/Th2) and interferon gamma INF-γ (INF-γ/Th1) inflammatory milieu found in the airways of patients with aspirin-exacerbated respiratory disease (AERD) is responsible for the altered regulation of the IL-1β/IL-1RI-/EP2/COX-2 autocrine loop also found i...

journal_title：Respiratory medicine

authors： Machado-Carvalho L,Roca-Ferrer J,Picado C

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVES:Acid gastro-esophageal reflux has been shown associated with chronic pulmonary diseases. The role of non-acid refluxes in these children is still unknown. Therefore we investigated the prevalence of acid and non-acid refluxes, and their association with desaturations, in children with chronic pulmonary sympt...

journal_title：Respiratory medicine

authors： Thilmany C,Beck-Ripp J,Griese M

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Laparoscopic adjustable gastric banding surgery has become one of the most common restrictive surgical procedures for treatment of morbid obesity worldwide. Although short-term respiratory complications are well known, long-term data is scarce. We investigated the manifestations of major pulmonary complicati...

journal_title：Respiratory medicine

authors： Avriel A,Warner E,Avinoach E,Avnon LS,Shteinberg M,Shteinberg D,Heimer D,Yona S,Maimon N

更新日期：2012-08-01 00:00:00

abstract：:Behçet's disease (BD) is a multisystemic disease that may involve all systems, the most common symptoms being oral and genital ulcerations and ocular involvement. Pulmonary involvement is not usually investigated in BD unless there is a specific complaint. In this study, pulmonary parameters and findings were investig...

journal_title：Respiratory medicine

authors： Bilgin G,Sungur G,Kucukterzi V

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:A clinical stability (CS) evaluation is thought to be important in community-acquired pneumonia (CAP) treatment, but evidence concerning the time to CS (TCS) remains lacking. METHODS:Among consecutive patients hospitalized with pneumococcal pneumonia, relationships between TCS and other clinical outcomes we...

journal_title：Respiratory medicine

authors： Takada K,Matsumoto S,Kojima E,Iwata S,Ninomiya K,Tanaka K,Goto D,Shimizu T,Nohara K

更新日期：2014-05-01 00:00:00

abstract：:Oxygen therapy for use in the home can be prescribed in two forms: oxygen concentrators are used to provide long term domiciliary oxygen therapy (LTOT), and oxygen cylinders are used to provide oxygen intermittently for relief of symptoms. In this study prescription and usage of oxygen cylinders in the home were asses...

journal_title：Respiratory medicine

authors： Okubadejo AA,Paul EA,Wedzicha JA

更新日期：1994-11-01 00:00:00

abstract：:Recent developments in intrabronchial administration of insulin raise lung function in patients with type I diabetes as important issue. Several studies in adults report abnormalities of lung function of these patients. The aim of this study was to investigate lung function in children with type I diabetes. Twenty-sev...

journal_title：Respiratory medicine

authors： van Gent R,Brackel HJ,de Vroede M,van der Ent CK

更新日期：2002-12-01 00:00:00

abstract：:Lung cancer remains the most common cause of cancer-related mortality in Scotland, accounting for 28.9% of all cancer deaths in 2007. (1) Current guidelines recommend assessment of patient fitness and operability by a multi-disciplinary team when selecting management options. (2-6) Two of the most important prognostic...

journal_title：Respiratory medicine

authors： Tsim S,O'Dowd CA,Milroy R,Davidson S

更新日期：2010-12-01 00:00:00

abstract：:Snoring and obstructive sleep apnoea/hypopnoea syndrome (OSAHS) are often treated with mandibular repositioning splints (MRS), but the efficacy and satisfaction of them has not been comprehensively addressed. A survey on the use of and satisfaction with MRS was posted to 177 patients referred by a hospital orthodontic...

journal_title：Respiratory medicine

authors： Izci B,McDonald JP,Coleman EL,Mackay TW,Douglas NJ,Engleman HM

更新日期：2005-03-01 00:00:00

abstract：:The aim of this study was to investigate the effects of various pretreatment clinical and laboratory characteristics on the survival of patients with diffuse malignant pleural mesothelioma (DMPM). One hundred histopathologically confirmed DMPM patients were evaluated. Fifty-nine were treated with chemoimmunotherapy wh...

journal_title：Respiratory medicine

authors： Metintas M,Metintas S,Ucgun I,Gibbs AR,Harmanci E,Alatas F,Erginel S,Tel N,Pasaoglu O

更新日期：2001-10-01 00:00:00

abstract：:Late allergic reactions (LAR) following allergen challenge occur in different compartments. We studied the kinetics of nasal and bronchial nitric oxide (NO) in mild asthmatics after allergen challenge. Twelve males with intermittent asthma (28 yr, FEV1 97% of predicted, PC20methacholine <8 mg/ml) and known LAR after b...

journal_title：Respiratory medicine

authors： Korn S,Beier J,Heilmann C,Kornmann O,Buhl R,Michael Beeh K

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:The synergistic interactions between pharmacotherapy and pulmonary rehabilitation has been provided, but it remains to be established whether this may also apply to more severe patients. OBJECTIVES:We have examined whether tiotropium enhances the effects of exercise training in patients with advanced COPD (...

journal_title：Respiratory medicine

authors： Pasqua F,Biscione G,Crigna G,Auciello L,Cazzola M

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Little is known about trends in the utilization or complication rates of transbronchial lung biopsy, particularly in community hospitals. METHODS:We used the Healthcare Cost and Utilization Project Florida State Inpatient and State Ambulatory Surgical Databases to assess trends in transbronchial lung biopsy...

journal_title：Respiratory medicine

authors： Tukey MH,Wiener RS

更新日期：2012-11-01 00:00:00

abstract：AIMS:This study tested inhibitory effects of in vitro Montelukast treatment on nasal airway epithelial cells (AEC) cultured from asthmatic patients treated with Montelukast with and without concomitant allergic rhinitis. We further examined the effect of Montelukast withdrawal in these patients on cytokine release from...

journal_title：Respiratory medicine

authors： Scaife A,Miller D,Spiteri-Cornish D,Turner SW,Devereux GS,Walsh GM

更新日期：2013-12-01 00:00:00

abstract：:Patients with chronic obstructive pulmonary disease (COPD) are often characterised by a range of characteristic co-morbidities that interfere with their pulmonary disease. In addition to a mere association with co-morbidities, a complex pathophysiological interaction and mutual augmentation occurs between COPD and its...

journal_title：Respiratory medicine

authors： Doehner W,Haeusler KG,Endres M,Anker SD,MacNee W,Lainscak M

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Tracheal collapse is a weakness of the tracheal wall leading to expiratory central airway collapse of more than 50% compared to inspiration. It has previously been discussed whether the collapsibility of the greater airways is a stable or a dynamic condition. Indeed, other well-known lung diseases such as as...

journal_title：Respiratory medicine

authors： Nygaard M,Hilberg O,Rasmussen F,Bendstrup E

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Bronchial stenosis (BS) is currently found in 7-15% of lung transplantation (LT) recipients. Current treatment strategies have included Nd:Yag laser, cryotherapy, bougie dilatation and stent placement. Bronchoscopic balloon dilatation has been used as alternative treatment in a few cases with controversial r...

journal_title：Respiratory medicine

authors： De Gracia J,Culebras M,Alvarez A,Catalán E,De la Rosa D,Maestre J,Canela M,Román A

更新日期：2007-01-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) is a condition characterized by progressive airflow limitation, with symptoms of dyspnoea, cough, and sputum production. Aside from information on prevalence, mortality and hospital resource utilization arising from COPD in Canada, there is a lack of data on the impact of t...

journal_title：Respiratory medicine

authors： Chapman KR,Bourbeau J,Rance L

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Gas trapping suggesting small airway disease is observed in adult asthmatic suffering from severe asthma. The aim of the study was to assess whether gas trapping could be evidenced in asthmatic children with/without severe exacerbation and with/without symptoms during the past three months. METHODS AND PATI...

journal_title：Respiratory medicine

authors： Mahut B,Peiffer C,Bokov P,Beydon N,Delclaux C

更新日期：2010-08-01 00:00:00