Abstract:
BACKGROUND:Trends in prevalence of asthma and allergic diseases are still controversial, and rarely studied among adolescents at midpoint of puberty. METHODS:In 2000, a questionnaire was mailed to adolescents (n = 18,158) attending 9th grade at school and living in Västra Götaland County, Sweden. Eight years later, the same questionnaire was mailed to adolescents (n = 21,651), using identical inclusion criteria as previously. Altogether, 10,837 adolescents completed the questionnaire in 2000 and 11,754 in 2008. Differences in prevalence of physician diagnosed asthma, asthma symptoms, rhinitis, and eczema between the periods were analyzed by Chi-square test. Multiple logistic regression models were performed to test for trends in prevalence of these diseases, adjusting for potential confounders. RESULTS:Physician diagnosed asthma and lifetime and current rhinitis were increased in 2008, while wheeze decreased (p < 0.05). Taking sex, foreign descent, body mass index, and parents' education into account, the prevalence of physician diagnosed asthma (OR 1.3 [95% CI 1.2-1.4]) and lifetime (1.7 [1.6-1.8]) and current rhinitis (1.5 [1.4-1.6]) had increased. Eczema had decreased (0.9 [0.8-0.98]). These trends were consistent in boys and girls, but more prominent in those with obesity. In physician diagnosed asthmatics, there was no change in wheeze, asthma symptoms, or asthma medication. CONCLUSIONS:The prevalence of physician diagnosed asthma has increased over the last decade, maybe due to combinations of changes in diagnostics and increased general awareness, rather than a real increase. Results showed an increase in rhinitis and a decrease in eczema. Obesity seems to have a modifying effect, which calls for further investigation.
journal_name
Respir Medjournal_title
Respiratory medicineauthors
Kim JL,Brisman J,Aberg MA,Forslund HB,Winkvist A,Torén Kdoi
10.1016/j.rmed.2014.02.011subject
Has Abstractpub_date
2014-05-01 00:00:00pages
701-8issue
5eissn
0954-6111issn
1532-3064pii
S0954-6111(14)00084-5journal_volume
108pub_type
杂志文章abstract::The pathophysiology of corticosteroid-induced osteoporosis is complex, but centres around a primary inhibition of osteoblastic activity compounded by the effects of secondary hyperparathyroidism. The preservation of the microanatomy of bone in the early stages of the disease, coupled with strategies to prevent the eme...
journal_title:Respiratory medicine
pub_type: 杂志文章,评审
doi:10.1016/s0954-6111(05)80252-5
更新日期:1993-02-01 00:00:00
abstract:OBJECTIVE:To determine the characteristics of persons with cognitive impairment being able to self-manage in chronic obstructive pulmonary disease (COPD). METHODS:In accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidance this systematic review examined all studies in E...
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pub_type: 杂志文章,评审
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更新日期:2017-08-01 00:00:00
abstract::Exposure to air pollution is associated with adverse health effects, with particulate matter (PM) and ozone (O(3)) both indicated to be of considerable importance. Diesel engine exhaust (DE) and O(3) generate substantial inflammatory effects in the airways. However, as yet it has not been determined whether a subseque...
journal_title:Respiratory medicine
pub_type: 杂志文章,随机对照试验
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更新日期:2007-06-01 00:00:00
abstract:BACKGROUND:COPD patients who remain hypercapnic after acute respiratory failure requiring mechanical ventilation have a poor prognosis. Long-term nocturnal non-invasive ventilation (NIV) may be beneficial for these patients. We hypothesized that stable patients on long-term NIV would experience clinical worsening after...
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pub_type: 杂志文章,随机对照试验
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更新日期:2011-03-01 00:00:00
abstract::In 16 patients with pulmonary fibrosis, an artificial pneumothorax was introduced using the Veress cannula and the Saugman water manometer. Atmospheric air was introduced by fractionated insufflation to a total volume of 800 ml (median). The interpleural space was found on the first attempt, and in all cases, fraction...
journal_title:Respiratory medicine
pub_type: 临床试验,杂志文章
doi:10.1016/s0954-6111(97)90253-5
更新日期:1997-08-01 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:2018-07-01 00:00:00
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journal_title:Respiratory medicine
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更新日期:2007-08-01 00:00:00
abstract:BACKGROUND:Hospitalization attributed to severe exacerbations is the major cost driver of Chronic Obstructive Pulmonary Disease (COPD). Given that in Greece no previous studies have addressed the economic burden of COPD, the aim of the study was to examine the hospitalization cost of COPD patients with severe exacerbat...
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更新日期:2011-03-01 00:00:00
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更新日期:2011-03-01 00:00:00
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更新日期:2004-11-01 00:00:00
abstract::Pneumocystis carinii colonization was studied in 90 men using the polymerase chain reaction. These comprised ten heterosexual controls; ten HIV-seronegative homosexual controls; 20 HIV-seropositive homosexuals with blood CD4 count > 400 x 10(6) l-1; 20 HIV-seropositive homosexuals with CD4 < 400 x 10(6) l-1; ten HIV-s...
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更新日期:1993-10-01 00:00:00
abstract::Few recent comparative data exist on smoking habits in the Middle East and North Africa (MENA) region. The objective of this analysis was to evaluate smoking patterns in a large general population sample of individuals aged ≥ 40 years in ten countries in the region (Algeria, Egypt, Jordan, Lebanon, Morocco, Saudi Arab...
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更新日期:2012-12-01 00:00:00
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doi:10.1016/s0954-6111(98)90296-7
更新日期:1998-03-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.rmed.2011.07.021
更新日期:2012-02-01 00:00:00
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journal_title:Respiratory medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1053/rmed.1999.0749
更新日期:2000-03-01 00:00:00
abstract::Heart-lung transplantation involves denervation of the lungs below the tracheal anastomosis, with associated permanent loss of all pulmonary innervation except post-ganglionic efferent nerves. This is supported by loss of the cough reflex to inhaled USNDW, which also implies that the RARs which mediate this cough mech...
journal_title:Respiratory medicine
pub_type: 杂志文章
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更新日期:1991-01-01 00:00:00
abstract::Intrapulmonary percussive ventilation (IPV) is a ventilatory technique that delivers bursts of high-flow respiratory gas into the lung at high rates, intended for treating acute respiratory failure and for mobilization of secretions. We performed a study, aimed at assessing the physiological response to IPV, on patien...
journal_title:Respiratory medicine
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doi:10.1016/j.rmed.2006.01.010
更新日期:2006-09-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:It has been reported that adverse fetal outcomes are more prevalent in pregnant women with asthma than they are in women without asthma. In our study, we investigated the effect that the severity of asthma during pregnancy has on the risk of a small for gestational age (SGA) infant, low birth weig...
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doi:10.1016/j.rmed.2010.03.010
更新日期:2010-09-01 00:00:00
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更新日期:2006-02-01 00:00:00
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更新日期:2009-07-01 00:00:00
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更新日期:2010-01-01 00:00:00
abstract::A case of endobronchial metastasis 2 yr following treatment of rectal carcinoma is presented. Endobronchial metastases from extrathoracic primary malignancies are uncommon, the estimated frequency and possible mechanisms underlying this complication are discussed. The importance of recognizing possible endobronchial m...
journal_title:Respiratory medicine
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doi:10.1016/s0954-6111(97)90047-0
更新日期:1997-04-01 00:00:00
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pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2005-04-01 00:00:00
abstract:BACKGROUND:Asthma treatment per Global Initiative for Asthma (GINA) guidelines targets airway remodeling and achievement of normal lung function. OBJECTIVE:To study inhaled steroid therapy on airway remodeling and achievement of normal lung function. SUBJECTS AND SET UP: Asthmatic patients were followed over 5 years ....
journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/j.rmed.2005.06.011
更新日期:2006-03-01 00:00:00
abstract::Weight loss has been recognized as a feature of advanced emphysema and a factor of poor prognosis, but its mechanisms remain obscure. Studies have demonstrated high serum concentrations of TNF-a (cachexin) in chronic obstructive pulmonary disease (COPD) patients with emphysema. Pink puffers (PP) COPD patients have wor...
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pub_type: 杂志文章
doi:10.1053/rmed.2002.1322
更新日期:2002-08-01 00:00:00
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journal_title:Respiratory medicine
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更新日期:2016-07-01 00:00:00
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journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/j.rmed.2009.01.011
更新日期:2009-07-01 00:00:00
abstract:INTRODUCTION:Antibodies against mimivirus, a recently discovered giant virus, have been found in patients presenting with pneumonia suggesting a potential role for this virus as a respiratory pathogen. Several bacterial and viral pathogens have been associated with the occurrence of acute exacerbations in COPD. However...
journal_title:Respiratory medicine
pub_type: 杂志文章
doi:10.1016/j.rmed.2012.08.019
更新日期:2012-12-01 00:00:00
abstract::Both albuterol and nedocromil sodium have been recognized to possess certain anti-inflammatory properties. However, there are no data on the impact of these drugs on the pathophysiology of the bronchial extracellular matrix in asthma characterized by enhanced tenascin (Tn) expression, known to occur proportional to th...
journal_title:Respiratory medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0954-6111(99)90086-0
更新日期:1999-07-01 00:00:00