Factors affecting SP-A-mediated phagocytosis in human monocytic cell lines.

abstract：:The imbalance between oxidants and antioxidants is known to play an important role in the pathogenesis of chronic obstructive pulmonary disease (COPD). Cigarette smoking is the most frequent factor responsible for development of COPD by leading to oxidant overload in the lower airways, due to presence of its own oxida...

journal_title：Respiratory medicine

authors： Nowak D,Kasielski M,Antczak A,Pietras T,Bialasiewicz P

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:Although the utility of blind biopsy in the detection of metastasis in the carina has been reported, submucosal fine needle aspiration (SMFNA) has not been evaluated. We investigated how SMFNA of the main carina and upper-lobe carina in addition to blind biopsy affect management of patients with NSCLC. METH...

journal_title：Respiratory medicine

authors： Kaynar H,Meral M,Ucar EY,Saglam L,Yildirim U,Gorguner M,Akgun M

更新日期：2011-10-01 00:00:00

abstract：UNLABELLED:Misdiagnoses are inevitable when working hypotheses of asthma/COPD of General Practitioners (GPs) are not checked by spirometry. To reduce misdiagnoses, Asthma/COPD-support services (AC-services) offer support by performing spirometry assessed together with written medical history by consulting pulmonologist...

journal_title：Respiratory medicine

authors： Lucas AE,Smeenk FJ,Smeele IJ,van Schayck OP

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:We aimed to compare chest low-dose computed tomography (LDCT) with chest radiography (CXR) in the assessment of febrile acute myeloid leukaemia neutropenic patients. METHODS:A prospective non-randomized study was carried out between 30 May, 2003 and 3 June, 2004 in consecutive neutropenic patients who requi...

journal_title：Respiratory medicine

authors： Patsios D,Maimon N,Chung T,Roberts H,Disperati P,Minden M,Paul N

更新日期：2010-04-01 00:00:00

abstract：:Healthcare payers are faced with the need to allocate finite resources to maximize population health. To assist in decision-making, healthcare payers are increasingly using health outcomes information and economic analyses. Healthcare payers are often under pressure to make early decisions (around the time of product ...

journal_title：Respiratory medicine

authors： Levine M,Taylor R,Ryan M,Sculpher M

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:The role of computerised tomography (CT) lung density measurements in objective quantification of emphysema is uncertain. The aim of this study was to determine normal reference values for CT lung density measurements and investigate their utility in identifying subjects with clinical emphysema. METHODS:Nor...

journal_title：Respiratory medicine

authors： Marsh S,Aldington S,Williams MV,Nowitz MR,Kingzett-Taylor A,Weatherall M,Shirtcliffe PM,McNaughton AA,Pritchard A,Beasley R

更新日期：2007-07-01 00:00:00

abstract：:To answer the question as to whether pulmonary rehabilitation programs (PRP) induced increase in exercise tolerance (ET) is associated with increased levels of exhaled nitric oxide (eNO) in COPD patients of different degrees of severity, we designed a prospective and controlled study. Forty-seven stable COPD patients ...

journal_title：Respiratory medicine

authors： Clini E,Bianchi L,Foglio K,Vitacca M,Ambrosino N

更新日期：2002-05-01 00:00:00

abstract：:Induced sputum and bronchoalveolar lavage (BAL) are widely used for retrieving cells and soluble materials for studies of airway inflammation. Centrifuged cell samples are suitable for immunochemical identification of cellular products. The aim was to determine the optimal fixation procedure to detect intracellular an...

journal_title：Respiratory medicine

authors： Metso T,Haahtela T,Sevéus L

更新日期：2002-11-01 00:00:00

abstract：INTRODUCTION:Non-cystic fibrosis(CF) bronchiectasis has been recognized in children for the past 200 years. Early childhood pneumonia and underlying conditions such as immunodeficiency, primary ciliary dyskinesia(PCD), and congenital lung pathology should be considered in the etiology. The aim of our study was to descr...

journal_title：Respiratory medicine

authors： Satırer O,Mete Yesil A,Emiralioglu N,Tugcu GD,Yalcın E,Dogru D,Kiper N,Ozcelik U

更新日期：2018-04-01 00:00:00

abstract：:Patients with immune deficiencies can present with variable clinical phenotypes. This often translates into a significant delay in their diagnosis, and resultant patient morbidity. This review summarises the most common types of immunodeficiency disorders, primary and secondary, along with their key features. It provi...

journal_title：Respiratory medicine

authors： Grammatikos A,Bright P,Bhatnagar R,Johnston S

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Gas trapping suggesting small airway disease is observed in adult asthmatic suffering from severe asthma. The aim of the study was to assess whether gas trapping could be evidenced in asthmatic children with/without severe exacerbation and with/without symptoms during the past three months. METHODS AND PATI...

journal_title：Respiratory medicine

authors： Mahut B,Peiffer C,Bokov P,Beydon N,Delclaux C

更新日期：2010-08-01 00:00:00

abstract：:Idiopathic pulmonary fibrosis is the most common of the idiopathic interstitial lung diseases referring to the histo-pathological entity of usual interstitial pneumonia. It has been hypothesized that inflammation may trigger the multiformic fibrotic lesions found in the affected lung, and defects in the innate immune ...

journal_title：Respiratory medicine

authors： Hodgson U,Tukiainen P,Laitinen T

更新日期：2005-03-01 00:00:00

abstract：INTRODUCTION:Up to 40% of patients seen in a cough clinic have unexplained chronic cough. The long term outcome of these patients is uncertain. OBJECTIVE:To determine the long-term outcome in patients diagnosed with unexplained chronic cough. METHODS:We have performed a longitudinal study of symptoms, airway inflamma...

journal_title：Respiratory medicine

authors： Yousaf N,Montinero W,Birring SS,Pavord ID

更新日期：2013-03-01 00:00:00

abstract：:The ability of immunotherapy with heat-killed Mycobacterium vaccae (NCTC 11659), as an addition to the available chemotherapy, to improve the outcome in patients with multi-drug-resistant tubercle bacilli (MDRTB) who had not been cured by chemotherapy alone was evaluated in tuberculosis centres in Estonia, Iran, Kuwai...

journal_title：Respiratory medicine

authors： Stanford JL,Stanford CA,Grange JM,Lan NN,Etemadi A

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND:Dysregulation of the prostaglandin E2 (PGE2) signaling pathway has been implicated in interstitial pneumonia (IP) pathogenesis. Due to the unstable nature of PGE2, available detection methods may not precisely reflect PGE2 levels. We explored the clinical usefulness of measuring stable prostaglandin E-major ...

journal_title：Respiratory medicine

authors： Horikiri T,Hara H,Saito N,Araya J,Takasaka N,Utsumi H,Yanagisawa H,Hashimoto M,Yoshii Y,Wakui H,Minagawa S,Ishikawa T,Shimizu K,Numata T,Arihiro S,Kaneko Y,Nakayama K,Matsuura T,Matsuura M,Fujiwara M,Okayasu I,I

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:We examined the association between different adiposity indices and pulmonary function in Chinese adults in the Guangzhou Biobank Cohort Study (GBCS). METHODS:Participants with body mass index (BMI) < 18.5 (underweight) were excluded. Adiposity indices including BMI, waist circumference (WC), waist hip ratio...

journal_title：Respiratory medicine

authors： Pan J,Xu L,Lam TH,Jiang CQ,Zhang WS,Jin YL,Zhu F,Zhu T,Thomas GN,Cheng KK,Adab P

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Natriuretic peptides are considered as reliable indicators of left-heart failure (HF) and are useful for differential diagnosis of dyspnoea. AIM:We evaluated the clinical significance of N-terminal pro-brain natriuretic peptide (NT-proBNP) in patients with chronic hypercapnic respiratory failure (CHRF). ME...

journal_title：Respiratory medicine

authors： Budweiser S,Luchner A,Jörres RA,Heinemann F,Hitzl AP,Schmidbauer K,Riegger G,Pfeifer M

更新日期：2007-09-01 00:00:00

abstract：:We studied the effects of chronic nocturnal hypoxaemia due to obstructive sleep apnoea syndrome (OSAS) on the hypothalamic-pituitary-thyroid and hypothalamic-pituitary-testicular axes and on catecholamine and cortisol secretion. We investigated whether hormones other than catecholamines may serve as markers for chroni...

journal_title：Respiratory medicine

authors： Bratel T,Wennlund A,Carlström K

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Selection of heath-related quality of life (HRQL) instruments that are most responsive to changes in HRQL prevents investigators from drawing false-negative conclusions about the effectiveness of an intervention. The objective of this study was to compare the responsiveness of the Chronic Respiratory Questio...

journal_title：Respiratory medicine

authors： Puhan MA,Guyatt GH,Goldstein R,Mador J,McKim D,Stahl E,Griffith L,Schünemann HJ

更新日期：2007-02-01 00:00:00

abstract：:Patients with COPD are at risk for other comorbid diseases, like heart failure, coronary heart disease, and depression. However, little is known about COPD phenotypes and prevalence of sub-clinical renal failure. 433 COPD patients and 233 subjects without COPD, from Western Norway, age 40-75, GOLD stage II-IV, were ex...

journal_title：Respiratory medicine

authors： Gjerde B,Bakke PS,Ueland T,Hardie JA,Eagan TM

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Studies have shown that peak circulatory power (peak CircP; peak oxygen uptake × peak systolic blood pressure) is a variable predictor of prognosis in patients with left heart failure. It remains unknown whether peak CircP also predicts outcome in patients with idiopathic pulmonary arterial hypertension (IPA...

journal_title：Respiratory medicine

authors： Tang Y,Yao L,Liu Z,Xie W,Ma X,Luo Q,Zhao Z,Huang Z,Gao L,Jin Q,Yu X,Xiong C,Ni X,Yan Y,Qi W

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:Small fiber neuropathy commonly affects patients with sarcoidosis and is often refractory to standard immunosuppressive therapies used for systemic disease. The clinical features of sarcoidosis-associated small fiber neuropathy (SSFN) and its response to medical therapy have not been described in a large popu...

journal_title：Respiratory medicine

authors： Tavee JO,Karwa K,Ahmed Z,Thompson N,Parambil J,Culver DA

更新日期：2017-05-01 00:00:00

abstract：:Aminophylline administration was compared in 43 patients who died from asthma and 43 matched controls who were admitted, suffering from acute asthma, to hospitals in the North East Thames Region. A computer program, which used information about individual characteristics, medical history and drug intake, was employed ...

journal_title：Respiratory medicine

authors： Eason J,Markowe HL

更新日期：1989-05-01 00:00:00

abstract：:Antifibrotic drugs for idiopathic pulmonary fibrosis patients in England and Scotland are only available to those with FVC percent predicted (FVC%pred) less than or equal to 80%. The prescribing guidance does not state which set of reference values should be used and we show that a patient's FVC%pred can change by 4-6...

journal_title：Respiratory medicine

authors： Ward K,Spurr L,Goldman NR,Margaritopoulos GA,Kokosi M,Renzoni E,Chua F,Maher TM,Ward S,Wells AU

更新日期：2016-11-01 00:00:00

abstract：:Primary ciliary dyskinesia (PCD) is a genetic condition resulting in bronchiectasis. Exhaled gas nitric oxide (FE(NO)) is reduced in PCD. A model of pulmonary NO exchange dynamics can be used to demonstrate relative contributions of bronchial (J'aw(NO)) and peripheral airway (Calv(NO)) NO to the final FE(NO) concentra...

journal_title：Respiratory medicine

authors： Shoemark A,Wilson R

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Interstitial lung disease (ILD) is a common extramuscular manifestation of the idiopathic inflammatory myopathies (IIMs), dermatomyositis (DM) and polymyositis (PM). Patients with antisynthetase antibodies (ASA) demonstrate some or all of the features of the antisynthetase syndrome including IIM and ILD. It ...

journal_title：Respiratory medicine

authors： Johnson C,Connors GR,Oaks J,Han S,Truong A,Richardson B,Lechtzin N,Mammen AL,Casciola-Rosen L,Christopher-Stine L,Danoff SK

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Clinical significance of isolation of nontuberculous mycobacteria (NTM) from respiratory specimens in patients with pulmonary tuberculosis is unknown. This study aimed to investigate the prevalence and clinical impact of NTM in pulmonary tuberculosis patients. METHODS:We retrospectively reviewed data of pat...

journal_title：Respiratory medicine

authors： Huang CT,Tsai YJ,Shu CC,Lei YC,Wang JY,Yu CJ,Lee LN,Yang PC,Tami Group.

更新日期：2009-10-01 00:00:00

abstract：:The fine particle dose delivered via dry powder inhalers (DPIs) is often affected by the inspiratory flow rate generated during inhalation. This has clinical implications, since the fine particle dose determines the amount of drug reaching the lungs. With Easyhaler DPI the fine particle dose remains relatively constan...

journal_title：Respiratory medicine

authors： Koskela T,Malmström K,Sairanen U,Peltola S,Keski-Karhu J,Silvasti M

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) is a common disease worldwide with significant morbidity and mortality. AIM:To investigate the effect of a comprehensive COPD management programme in decreasing COPD readmissions 1 year before and 1 year after the programme. METHOD:185 (166 males) patients admit...

journal_title：Respiratory medicine

authors： Ko FW,Ngai JC,Ng SS,Chan KP,Cheung R,Leung MY,Pun MC,Hui DS

更新日期：2014-12-01 00:00:00

abstract：:Few recent comparative data exist on smoking habits in the Middle East and North Africa (MENA) region. The objective of this analysis was to evaluate smoking patterns in a large general population sample of individuals aged ≥ 40 years in ten countries in the region (Algeria, Egypt, Jordan, Lebanon, Morocco, Saudi Arab...

journal_title：Respiratory medicine

authors： Khattab A,Javaid A,Iraqi G,Alzaabi A,Ben Kheder A,Koniski ML,Shahrour N,Taright S,Idrees M,Polatli M,Rashid N,El Hasnaoui A,BREATHE Study Group.

更新日期：2012-12-01 00:00:00