Decision-making by healthcare payers.

abstract：INTRODUCTION:In vivo, the airway epithelium stretches and relaxes with each respiratory cycle, but little is known about the effect this pattern of elongation and relaxation has on bronchial epithelial cells. We have used a model of cell deformation to measure the effect of stretch on inflammatory cytokine release by t...

journal_title：Respiratory medicine

authors： Thomas RA,Norman JC,Huynh TT,Williams B,Bolton SJ,Wardlaw AJ

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Apoptosis is thought to play an important role in the development of acute respiratory distress syndrome (ARDS). We evaluated the bronchoalveolar lavage (BAL) fluid from ARDS patients focusing on apoptosis. METHODS:The study enrolled 31 ARDS patients and 20 healthy controls. BAL fluid levels of caspase-clea...

journal_title：Respiratory medicine

authors： Lee KS,Choi YH,Kim YS,Baik SH,Oh YJ,Sheen SS,Park JH,Hwang SC,Park KJ

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Pneumonia is a leading cause of morbidity and mortality in children worldwide; however, its diagnosis can be challenging, especially in settings where skilled clinicians or standard imaging are unavailable. We sought to determine the diagnostic accuracy of lung ultrasound when compared to radiographically-co...

journal_title：Respiratory medicine

authors： Ellington LE,Gilman RH,Chavez MA,Pervaiz F,Marin-Concha J,Compen-Chang P,Riedel S,Rodriguez SJ,Gaydos C,Hardick J,Tielsch JM,Steinhoff M,Benson J,May EA,Figueroa-Quintanilla D,Checkley W,Lung Ultrasound for Pneumonia Asse

更新日期：2017-07-01 00:00:00

abstract：:To document the rate and cost of antibiotic prescribing for patients diagnosed only with influenza during US ambulatory care visits. Federal survey data for 1997-2001 were used to estimate outpatient trends for all patients and healthy people age 5-49 years. Cost estimates were based on Medicare payments and Red Book ...

journal_title：Respiratory medicine

authors： Ciesla G,Leader S,Stoddard J

更新日期：2004-11-01 00:00:00

abstract：:The p53 gene is well known as a tumour suppressor gene. In addition, the mutated p53 gene is detected in a variety of human cancers including lung cancer, and is considered as an oncogene. Lung cancer is also frequently associated with interstitial lung diseases. Therefore, it may be possible to hypothesize that there...

journal_title：Respiratory medicine

authors： Hojo S,Fujita J,Yamadori I,Kamei T,Yoshinouchi T,Ohtsuki Y,Yamaji Y,Takahara J

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:Neuromuscular electrical stimulation (NMES) improves muscle performance and exercise tolerance in chronic obstructive pulmonary disease (COPD) patients. In contrast, no study has assessed the effect of NMES on dynamic hyperinflation (DH) in COPD. This study investigated the effect of short-term, high-frequen...

journal_title：Respiratory medicine

authors： Vieira PJ,Chiappa AM,Cipriano G Jr,Umpierre D,Arena R,Chiappa GR

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Idiopathic pulmonary fibrosis (IPF) is a fibroproliferative disorder. Cytokines contribute an important but yet undefined role to its pathogenesis. OBJECTIVES:The present study aims to compare serum levels of cytokines involved in Th-1 and Th-2 immunity, such as interleukins (IL) IL-2, IL-4, IL-8, IL-10, in...

journal_title：Respiratory medicine

authors： Tsoutsou PG,Gourgoulianis KI,Petinaki E,Germenis A,Tsoutsou AG,Mpaka M,Efremidou S,Molyvdas PA

更新日期：2006-05-01 00:00:00

abstract：:Intrapulmonary percussive ventilation (IPV) is a ventilatory technique that delivers bursts of high-flow respiratory gas into the lung at high rates, intended for treating acute respiratory failure and for mobilization of secretions. We performed a study, aimed at assessing the physiological response to IPV, on patien...

journal_title：Respiratory medicine

authors： Nava S,Barbarito N,Piaggi G,De Mattia E,Cirio S

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Several animal studies, and one inoculation study in adult asthmatics have shown that interleukin-33 (IL-33) is a major contributor to type-2 inflammation in acute asthma. However, the link between IL-33 and type-2 inflammation has not been shown in naturally occurring asthma exacerbations. OBJECTIVES:To de...

journal_title：Respiratory medicine

authors： Poulsen NN,Bjerregaard A,Khoo SK,Laing IA,Le Souëf P,Backer V,Rapley L,Cohen SE,Barrett L,Thompson P,Baltic S,Porsbjerg C

更新日期：2018-07-01 00:00:00

abstract：PURPOSE:The aim of this retrospective study is to present data on clinical significance of lactate dehydrogenase (LDH) serum levels in an unselected contemporary patient population with small cell lung cancer (SCLC) in limited disease (LD) and extensive disease stage (ED). PATIENTS AND METHODS:From June 2004 to June 2...

journal_title：Respiratory medicine

authors： Hermes A,Gatzemeier U,Waschki B,Reck M

更新日期：2010-12-01 00:00:00

abstract：INTRODUCTION:Primary ciliary dyskinesia (PCD) is a rare genetically heterogeneous disorder of motile cilia, which leads to recurrent and chronic airway infections. Detailed information about infection causing pathogens is scarce. With this study, we aimed to determine the prevalence and susceptibility of the most commo...

journal_title：Respiratory medicine

authors： Roden L,Görlich D,Omran H,Peters G,Große-Onnebrink J,Kahl BC

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:To analyse the relationship between symptoms at different times during the 24-hour day and outcomes in COPD. METHODS:Observational cross-sectional study in a patients from 7 Latin American countries. The frequency of symptoms in the morning, at night and during the day was explored by means of standardised ...

journal_title：Respiratory medicine

authors： Miravitlles M,Menezes A,López Varela MV,Casas A,Ugalde L,Ramirez-Venegas A,Mendoza L,López A,Wehrmeister FC,Surmont F,Montes de Oca M

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Chronic pulmonary aspergillosis (CPA) is associated with mortality in patients with Mycobacterium avium complex lung disease (MAC-LD). However, the clinical significance of the positivity of Aspergillus precipitating antibody (APAb), a serodiagnostic test for pulmonary aspergillosis (PA), at th...

journal_title：Respiratory medicine

authors： Shirai T,Furuuchi K,Fujiwara K,Nakamoto K,Tanaka Y,Ishii H,Yoshiyama T,Yoshimori K,Takizawa H,Sasaki Y,Kurashima A,Ohta K,Morimoto K

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:We hypothesized that increased pulmonary vascular permeability may play a role in the pathogenesis of an acute exacerbation of the idiopathic interstitial pneumonias (AE-IIPs). Angiopoietin-2 (Ang-2) promotes endothelial activation, destabilization, and inflammation. The purpose of this study w...

journal_title：Respiratory medicine

authors： Ando M,Miyazaki E,Abe T,Ehara C,Goto A,Masuda T,Nishio S,Fujisaki H,Yamasue M,Ishii T,Mukai Y,Ito T,Nureki SI,Kumamoto T,Kadota J

更新日期：2016-08-01 00:00:00

abstract：:A case of endobronchial metastasis 2 yr following treatment of rectal carcinoma is presented. Endobronchial metastases from extrathoracic primary malignancies are uncommon, the estimated frequency and possible mechanisms underlying this complication are discussed. The importance of recognizing possible endobronchial m...

journal_title：Respiratory medicine

authors： Lee YC,Wong CS,Jeffery GM

更新日期：1997-04-01 00:00:00

abstract：:Heart-lung transplantation involves denervation of the lungs below the tracheal anastomosis, with associated permanent loss of all pulmonary innervation except post-ganglionic efferent nerves. This is supported by loss of the cough reflex to inhaled USNDW, which also implies that the RARs which mediate this cough mech...

journal_title：Respiratory medicine

authors： Hathaway T,Higenbottam T,Lowry R,Wallwork J

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Traditionally, outpatient visits for COPD are fixed, pre-planned by the pulmonologist. This is not a patient centered method, nor, in times of increasing COPD prevalence and resource constraints, perhaps the optimal method. OBJECTIVES:This pilot study, determined the effect of an on-demand-system, patient i...

journal_title：Respiratory medicine

authors： Berkhof FF,Hesselink AM,Vaessen DL,Uil SM,Kerstjens HA,van den Berg JW

更新日期：2014-08-01 00:00:00

abstract：:We have recently found that changes in lung sounds correspond well with a 20% fall in the forced expiratory volume in 1 s (FEV1) after methacholine challenge in asthmatic children. Up to now, little was known about the agreement between a 20% fall in FEV1 and a change in lung sounds after repeated bronchial challenge....

journal_title：Respiratory medicine

authors： Sprikkelman AB,Schouten JP,Lourens MS,Heymans HS,van Aalderen WM

更新日期：1999-02-01 00:00:00

abstract：PURPOSE:A considerable body of non clinical evidence has accumulated to support peroxisomal proliferator-activated receptor gamma agonists as candidate anti-inflammatory drugs in asthma. We utilized rosiglitazone as a tool compound in the inhaled allergen challenge model of asthma. METHODS:A single centre, double-blin...

journal_title：Respiratory medicine

authors： Richards DB,Bareille P,Lindo EL,Quinn D,Farrow SN

更新日期：2010-05-01 00:00:00

abstract：:In the drive to replace chlorofluorinated hydrocarbons (CFCs) by alternative more environmentally friendly propellants in pressurized metered dose inhalers (pMDIs), Chiesi has developed new inhalers using Modulite technology. The aim was to obtain CFC-free pMDIs which are equivalent, in terms of safety and efficacy, t...

journal_title：Respiratory medicine

authors： Woodcock A,Acerbi D,Poli G

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:Patients with Chronic Obstructive Pulmonary Disease (COPD) are at higher risk of developing Community-Acquired Pneumonia (CAP) than patients in the general population. However, no studies have been performed in general practice assessing longitudinal incidence rates for CAP in COPD patients or risk factors f...

journal_title：Respiratory medicine

authors： Müllerova H,Chigbo C,Hagan GW,Woodhead MA,Miravitlles M,Davis KJ,Wedzicha JA

更新日期：2012-08-01 00:00:00

abstract：:Pneumocystis carinii colonization was studied in 90 men using the polymerase chain reaction. These comprised ten heterosexual controls; ten HIV-seronegative homosexual controls; 20 HIV-seropositive homosexuals with blood CD4 count > 400 x 10(6) l-1; 20 HIV-seropositive homosexuals with CD4 < 400 x 10(6) l-1; ten HIV-s...

journal_title：Respiratory medicine

authors： Leigh TR,Kangro HO,Gazzard BG,Jeffries DJ,Collins JV

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND:We have observed that Doctors often perceive that cystic fibrosis (CF) is exceptionally rare in non-whites, and that this bias has repeatedly resulted in diagnostic delay. We therefore compared the age at diagnosis, genetic features and relative prevalence of CF in non-whites and white patients in the West M...

journal_title：Respiratory medicine

authors： Spencer DA,Venkataraman M,Higgins S,Stevenson K,Weller PH

更新日期：1994-10-01 00:00:00

abstract：:The measurement of CA50 in serum and pleural fluid by immunoradiometric assay was presented in 45 (27 malignancy and 18 tuberculosis) patients with pleural effusion. The mean CA50 level in malignant effusion (89.26 +/- 122.32 U ml-1) was significantly higher than that in tuberculous effusion (5.18 +/- 8.65 U ml-1) (P ...

journal_title：Respiratory medicine

authors： Yang SZ,Ji SQ

更新日期：1994-01-01 00:00:00

abstract：UNLABELLED:Misdiagnoses are inevitable when working hypotheses of asthma/COPD of General Practitioners (GPs) are not checked by spirometry. To reduce misdiagnoses, Asthma/COPD-support services (AC-services) offer support by performing spirometry assessed together with written medical history by consulting pulmonologist...

journal_title：Respiratory medicine

authors： Lucas AE,Smeenk FJ,Smeele IJ,van Schayck OP

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:No consensus exists on the exact treatment of pneumothorax (PTX). Some guidelines are proposing manual aspiration (MA) to be preferred over tube thoracostomy (TT) in uncomplicated primary spontaneous pneumothorax (PSP). However, only a few studies reported a direct comparison of both methods. Our aim was to ...

journal_title：Respiratory medicine

authors： Parlak M,Uil SM,van den Berg JW

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:The current literature suggests a relationship between obstructive sleep apnea (OSA) severity and hematocrit. However, the degree that OSA contributes to clinically significant erythrocytosis is uncertain. The aim of this study is to evaluate this association in a large study sample controlling for multiple ...

journal_title：Respiratory medicine

authors： Nguyen CD,Holty JC

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Impaired cardiac function and sleep-disordered breathing (SDB) are associated with progression of chronic kidney disease (CKD) in heart failure (HF) patients. Adaptive servo-ventilation (ASV) therapy improves cardiac function in HF patients regardless of the SDB severity through hemodynamic support and preve...

journal_title：Respiratory medicine

authors： Koyama T,Watanabe H,Terada S,Makabe S,Igarashi G,Nobori K,Ito H

更新日期：2011-12-01 00:00:00

abstract：INTRODUCTION:Subjective fatigue has been recognised as an important, multi-component symptom in COPD. Pulmonary Rehabilitation (PR) improves fatigue component of the Chronic Respiratory Questionnaire, a quality of life (QoL) measure. However, it is not clear if all fatigue dimensions are affected equally. This study ai...

journal_title：Respiratory medicine

authors： Lewko A,Bidgood PL,Jewell A,Garrod R

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:COPD patients who remain hypercapnic after acute respiratory failure requiring mechanical ventilation have a poor prognosis. Long-term nocturnal non-invasive ventilation (NIV) may be beneficial for these patients. We hypothesized that stable patients on long-term NIV would experience clinical worsening after...

journal_title：Respiratory medicine

authors： Funk GC,Breyer MK,Burghuber OC,Kink E,Kirchheiner K,Kohansal R,Schmidt I,Hartl S

更新日期：2011-03-01 00:00:00