Retrospective study of bitolterol mesylate in the treatment of conditions associated with reversible bronchospasm.

abstract：INTRODUCTION:To evaluate the retinal function and the relative neural conduction along the visual pathway after treatment with citicoline in liposomal formulation (CLF) eye drops in patients with open angle glaucoma (OAG). METHODS:Twelve OAG patients (mean age ± standard deviation 52.58 ± 11.39 years, intraocular pres...

journal_title：Advances in therapy

authors： Parisi V,Oddone F,Roberti G,Tanga L,Carnevale C,Ziccardi L,Manni G

更新日期：2019-04-01 00:00:00

abstract：:In the last few years, immunotherapy has transformed the way we treat solid tumors, including melanoma, lung, head neck, breast, renal, and bladder cancers. Durable responses and long-term survival benefit has been experienced by many cancer patients, with favorable toxicity profiles of immunotherapeutic agents relati...

journal_title：Advances in therapy

authors： Arora S,Velichinskii R,Lesh RW,Ali U,Kubiak M,Bansal P,Borghaei H,Edelman MJ,Boumber Y

更新日期：2019-10-01 00:00:00

abstract：INTRODUCTION:Increasing dialysate magnesium (D-Mg2+) appears to be an intriguing strategy to obtain cardiovascular benefits in subjects with end-stage kidney disease (ESKD) on hemodialysis. To date, however, hemodialysis guidelines do not suggest to increase D-Mg2+ routinely set at 0.50 mmol/L. METHODS:A randomized 4-...

journal_title：Advances in therapy

authors： Del Giorno R,Lavorato Hadjeres S,Stefanelli K,Allegra G,Zapparoli C,Predrag L,Berwert L,Gabutti L

更新日期：2020-12-01 00:00:00

abstract：INTRODUCTION:The 1100delC CHEK2 allele has been associated with a 1.4-to 4.7-fold increased risk of breast cancer in women carrying this mutation. Our study investigated the frequency of this allele in a Chinese population. METHODS:Using touchdown polymerase chain reaction, we sequenced the CHEK2.1100delC mutation in ...

journal_title：Advances in therapy

authors： Chen W,Yurong S,Liansheng N

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:The OPTIMA© (MSD, Courbevoie, France) questionnaire was developed to promote shared decisions and the set-up of specific micro-objectives in clinical practice by optimizing communication between type 2 diabetes (T2DM) patients and their physicians. The present study aimed to assess OPTIMA in clinical practic...

journal_title：Advances in therapy

authors： Grimaldi A,Penfornis A,Consoli S,Falissard B,Eymard E,Williams P,Dejager S

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Studies assessing the effect of high dose tigecycline on severe infections are limited and remain controversial. OBJECTIVES:To assess systematically the effectiveness and safety of high dose tigecycline in the treatment of severe infections. METHODS:Pubmed, Web of Science, Embase, MEDLINE, Cochrane Library...

journal_title：Advances in therapy

authors： Zha L,Pan L,Guo J,French N,Villanueva EV,Tefsen B

更新日期：2020-03-01 00:00:00

abstract：:Adenoid cystic carcinoma (AdCC) of the head and neck is a well-recognized pathologic entity that rarely occurs in the larynx. Although the 5-year locoregional control rates are high, distant metastasis has a tendency to appear more than 5 years post treatment. Because AdCC of the larynx is uncommon, it is difficult to...

journal_title：Advances in therapy

authors： Coca-Pelaz A,Barnes L,Rinaldo A,Cardesa A,Shah JP,Rodrigo JP,Suárez C,Eloy JA,Bishop JA,Devaney KO,Thompson LD,Wenig BM,Strojan P,Hamoir M,Bradley PJ,Gnepp DR,Silver CE,Slootweg PJ,Triantafyllou A,Vander Poorten V,

更新日期：2016-04-01 00:00:00

abstract：:Venous leg ulcers (VLUs) are the most severe manifestation of chronic venous disease (CVD). Due to their chronic nature, high recurrence rate and slow healing time, VLUs account for 80% of all leg ulcers seen in patients with CVD. VLUs impose a heavy burden on patients that reduces their quality of life; VLUs also rep...

journal_title：Advances in therapy

authors： Nicolaides AN

更新日期：2020-02-01 00:00:00

abstract：:Available data from comparative trials involving 483 patients were analyzed to determine the rate of infectious morbidity following the use of absorbable staples versus traditional incision and suturing of the vaginal cuff in abdominal hysterectomy. Infections occurred in 24 of 268 (9%) patients who received absorbab...

journal_title：Advances in therapy

authors： Martens MG,Shailer LD

更新日期：1991-05-01 00:00:00

abstract：INTRODUCTION:Evidence suggests that elevated plasma levels of B-type natriuretic peptide (BNP) are found in patients with chronic obstructive pulmonary disease (COPD) and right ventricular dysfunction. We examined the effects of exercise on plasma BNP levels in patients with COPD who have normal right ventricular funct...

journal_title：Advances in therapy

authors： Gemici G,Erdim R,Celiker A,Tokay S,Ones T,Inanir S,Oktay A

更新日期：2008-07-01 00:00:00

abstract：INTRODUCTION:Spinal muscular atrophy (SMA) is a neurodegenerative disease of the motor neurons that results in progressive muscle weakness. It is also the leading hereditary cause of infant mortality. Homozygous loss of the survival motor neuron (SMN1) gene causes SMA, and the number of copies of the SMN2 gene modulate...

journal_title：Advances in therapy

authors： Dayangaç-Erden D,Topaloğlu H,Erdem-Yurter H

更新日期：2008-03-01 00:00:00

abstract：:The corneal toxicity of 2 intraocular pressure-lowering agents was compared in a rabbit cornea model with New Zealand White rabbits. Corneal epithelial morphology and cell size were assessed by in vivo confocal microscopy. Baseline microscopic examinations were performed on 1 eye of each animal. Two weeks later, the e...

journal_title：Advances in therapy

authors： Whitson JT,Cavanagh HD,Lakshman N,Petroll WM

更新日期：2006-09-01 00:00:00

abstract：:This double-blind, randomized, prospective study was conducted to compare the analgesic and sedative efficacy of fentanyl and meperidine in orthopedic closed reduction of fractures and dislocations undertaken in the emergency department. Seventy consecutive adult patients with fractures or dislocations suitable for re...

journal_title：Advances in therapy

authors： Soysal S,Karcioglu O,Demircan A,Topacoglu H,Serinken M,Ozucelik N,Tirpan K,Gunerli A

更新日期：2004-09-01 00:00:00

abstract：INTRODUCTION:This pooled analysis of data from three phase 3 studies in patients with chronic osteoarthritis knee or low back pain evaluated the efficacy and tolerability of tapentadol prolonged release (PR; 100-250 mg twice daily) compared with placebo and oxycodone hydrochloride (HCl) controlled release (CR; 20-50 mg...

journal_title：Advances in therapy

authors： Lange B,Kuperwasser B,Okamoto A,Steup A,Häufel T,Ashworth J,Etropolski M

更新日期：2010-06-01 00:00:00

abstract：INTRODUCTION:Although chronic opioid therapy is usually initiated using short-acting opioids, many patients with chronic pain are subsequently converted to long-acting and extended-release preparations. In clinical practice, optimal management requires careful individualization of dosage in order to achieve an appropri...

journal_title：Advances in therapy

authors： Nalamachu SR

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Mutation of human receptor tyrosine kinase epidermal growth factor receptor-2 (HER2) is a rare event, found in approximately 1% non-small cell lung cancers (NSCLC). The objective was to investigate the clinical characteristics and management of HER2-mutated NSCLCs in a real-life setting. METHODS:This multic...

journal_title：Advances in therapy

authors： Auliac JB,Dô P,Bayle S,Doubre H,Vinas F,Letreut J,Falchero L,Hauss PA,Thomas P,Chouaid C

更新日期：2019-08-01 00:00:00

abstract：INTRODUCTION:To date, no study has reported the prevalence of cannabis use in chronic pain patients. The aim of this study is to investigate the trends in cannabis use among chronic pain in-patients from 2011 to 2015 in the USA. METHODS:Patients were identified from the National Inpatient Sample (NIS) database using t...

journal_title：Advances in therapy

authors： Orhurhu V,Urits I,Olusunmade M,Olayinka A,Salisu Orhurhu M,Uwandu C,Aner M,Ogunsola S,Akpala L,Hirji S,Viswanath O,Karri J,Simopoulos T,Gill J

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak is a serious health concern. Repurposing of existing drugs indicated for other conditions seems to be the first choice for immediate therapeutic management. The quality of early evidence favoring the different treatment options needs t...

journal_title：Advances in therapy

authors： Subramanian K,Nalli A,Senthil V,Jain S,Nayak A,Bhat A

更新日期：2020-10-01 00:00:00

abstract：:Human papillomavirus (HPV) infection is one of the most common sexually transmitted infections in adolescents. Such infection is associated with substantial health risks and is unpredictable in its resolution. Genital warts are the most common clinical manifestations of genital HPV infections. Most genital warts are c...

journal_title：Advances in therapy

authors： Leung AK,Kellner JD,Davies HD

更新日期：2005-05-01 00:00:00

abstract：INTRODUCTION:Stimulant medications are the most effective drugs in the treatment of attention-deficit hyperactivity disorder (ADHD) in children and in adults. However, some patients do not respond to this treatment and other patients suffer from adverse effects. Very often there are also comorbid disorders that warrant...

journal_title：Advances in therapy

authors： Verbeeck W,Tuinier S,Bekkering GE

更新日期：2009-02-01 00:00:00

abstract：INTRODUCTION:This retrospective study evaluates the efficacy of palliative chemotherapy with a modified docetaxel, cisplatin, 5-fluorouracil (5-FU; "TPF" regimen) regimen (mTPF; reduced doses of docetaxel, cisplatin, and 5-FU with reduction of intravenous 5-FU from 4 days to 2 days) in Asian patients with recurrent and...

journal_title：Advances in therapy

authors： Lin JT,Lai GM,Chang TH,Liu MT,Bi CP,Wang JW,Chen MK

更新日期：2012-01-01 00:00:00

abstract：:Obesity is increasing in epidemic proportions globally while current therapies continue to be suboptimal. In this investigation, weight loss in obese individuals after 24 weeks with different nutrition interventions was compared. The impact of intervention intensity was assessed. Inclusion criteria were established an...

journal_title：Advances in therapy

authors： Anderson JW,Luan J,Høie LH

更新日期：2004-03-01 00:00:00

abstract：:Shock is a serious acute circulatory failure leading to inadequate oxygen delivery to the cells. Its treatment is mainly based on circulating fluid optimization, and vasopressors to provide an adequate mean arterial pressure and microcirculatory flow. Norepinephrine is the drug of choice, but high dosages may be respo...

journal_title：Advances in therapy

authors： Puntillo F,Giglio M,Pasqualucci A,Brienza N,Paladini A,Varrassi G

更新日期：2020-09-01 00:00:00

abstract：INTRODUCTION:High-dose intravenous esomeprazole is the only approved pharmacological treatment for the prevention of peptic ulcer rebleeding (currently approved in over 100 countries worldwide), but has not yet been approved in China. This study aimed to evaluate a high-dose esomeprazole intravenous regimen vs. an acti...

journal_title：Advances in therapy

authors： Bai Y,Chen DF,Wang RQ,Chen YX,Shi RH,Tian DA,Chen H,Eklund S,Li ZS,Chinese Peptic Ulcer Bleeding Research Group.

更新日期：2015-11-01 00:00:00

abstract：INTRODUCTION:This retrospective study used data from a primary care database to compare two insulin products in routine clinical practice for the treatment of type 2 diabetes in the UK. PATIENTS AND METHODS:Records were analyzed for patients with type 2 diabetes who had been initiated on biphasic insulin aspart 30 (BI...

journal_title：Advances in therapy

authors： Fakhoury WK,Richter H,Christensen TE

更新日期：2010-11-01 00:00:00

abstract：:The aim of this prospective, randomized, open-label, blinded endpoint (PROBE) study was to compare the antihypertensive efficacy of 2 angiotensin II (AII) receptor antagonists with different pharmacologic profiles, valsartan and olmesartan, in patients with mild-to-moderate essential hypertension. After an initial 2-w...

journal_title：Advances in therapy

authors： Destro M,Scabrosetti R,Vanasia A,Mugellini A

更新日期：2005-01-01 00:00:00

abstract：:With the increasing availability of biosimilars, the practice of switching therapies for non-medical reasons between an originator biologic and an analogous biosimilar has become more common. The evidence to support this practice mostly comes from single-switch randomized controlled trials (RCTs) and real-world (RW) e...

journal_title：Advances in therapy

authors： Feagan BG,Marabani M,Wu JJ,Faccin F,Spronk C,Castañeda-Hernández G

更新日期：2020-11-01 00:00:00

abstract：:A 54-y-old patient with rheumatoid arthritis (RA) and bilateral lower-limb lymphoedema is presented. Complete decongestive physical therapy (CDP) is the cornerstone of the management programme in all patients suffering from lymphoedema associated with RA, but it is not clear which therapy is the most effective in decr...

journal_title：Advances in therapy

authors： Eyigor S,Karapolat H,Kirazli Y

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION:Patients with chronic kidney disease (CKD) have an increased risk of comorbid conditions, including cardiovascular disease (CVD). Anemia is prevalent in the CKD population and worsens as kidney function declines, resulting in a diminished quality of life and increased morbidity/mortality. The purpose of th...

journal_title：Advances in therapy

authors： Covic A,Jackson J,Hadfield A,Pike J,Siriopol D

更新日期：2017-07-01 00:00:00

abstract：INTRODUCTION:Ivabradine has opened up new possibilities for treating stable angina and chronic heart failure by lowering heart rate. Ivabradine lowers heart rate by selectively inhibiting the I f current in the sinoatrial node. This study aimed to determine whether the decrease in heart rate achieved with ivabradine wa...

journal_title：Advances in therapy

authors： Jedlickova L,Merkovska L,Jackova L,Janicko M,Fedacko J,Novakova B,Chmelarova A,Majernik J,Pella D

更新日期：2015-10-01 00:00:00