Vasopressor-Sparing Action of Methylene Blue in Severe Sepsis and Shock: A Narrative Review.

abstract：INTRODUCTION:Adrenocortical carcinoma (ACC) is a rare malignancy with poor prognosis. It is vitally important to predict prognosis and restrict unnecessary adjuvant treatments for patients with ACC. This study aims to confirm the prognostic value of Ki-67 and provide a prognostic evaluation on ACC after primary surgery...

journal_title：Advances in therapy

authors： Zhang F,Zhang F,Liu Z,Wu K,Zhu Y,Lu Y

更新日期：2019-10-01 00:00:00

abstract：INTRODUCTION:Diabetic peripheral neuropathy (DPN) is one of the most common complications of diabetes and has been associated with cardiovascular disease, the leading cause of mortality in diabetes. As asymptomatic myocardial ischemia (MI) is frequent in diabetes, we hypothesized that DPN may be associated with MI in p...

journal_title：Advances in therapy

authors： Baltzis D,Roustit M,Grammatikopoulou MG,Katsaboukas D,Athanasiou V,Iakovou I,Veves A,Manes C,Trakatelli MC

更新日期：2016-10-01 00:00:00

abstract：INTRODUCTION:Recent research has suggested that serum tumor markers can give valuable prognostic information in gastric cancer. In this study, we examined the relationship between preoperative serum carcinoembryonic antigen (CEA), carbohydrate antigen (CA) 19-9, CA 72-4, and alfa fetoprotein (AFP) levels on clinicopath...

journal_title：Advances in therapy

authors： Ucar E,Semerci E,Ustun H,Yetim T,Huzmeli C,Gullu M

更新日期：2008-10-01 00:00:00

abstract：INTRODUCTION:Nivolumab has been approved in patients with melanoma with lymph node involvement or metastatic disease who have undergone complete resection, in the adjuvant setting. A pivotal trial compared nivolumab with ipilimumab; however, no head-to-head trial exists comparing nivolumab to observation, a common comp...

journal_title：Advances in therapy

authors： Freeman M,Betts KA,Jiang S,Du EX,Gupte-Singh K,Lu Y,Rao S,Shoushtari AN

更新日期：2019-10-01 00:00:00

abstract：INTRODUCTION:Rivastigmine is a cholinesterase inhibitor, approved for the treatment of mild-to-moderate dementia of Alzheimer's type. This study assessed the short- and long-term effectiveness and safety of rivastigmine in patients with mild-to-moderate Alzheimer's disease (AD) in a real-world clinical setting in Taiwa...

journal_title：Advances in therapy

authors： Chang CC,Peng GS,Lai TJ,Li CH,Liu CK

更新日期：2019-06-01 00:00:00

abstract：INTRODUCTION:The healthcare sector contributes 5-8% of the global greenhouse gas emissions. Global and regional organizations and governments have started to design and implement measures to reduce global greenhouse gas emissions in the healthcare sector, e.g. by green public procurement policies and inclusion of ecolo...

journal_title：Advances in therapy

authors： Ortsäter G,Borgström F,Soulard S,Miltenburger C

更新日期：2019-12-01 00:00:00

abstract：INTRODUCTION:Oral supplementation of chondroitin sulfate (CS) and glucosamine (GlcN), symptomatic slow-acting molecules, is recommended by European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis and Musculoskeletal Diseases (ESCEO) and other European Union (EU) guidelines for the restorati...

journal_title：Advances in therapy

authors： Stellavato A,Restaino OF,Vassallo V,Finamore R,Ruosi C,Cassese E,De Rosa M,Schiraldi C

更新日期：2019-11-01 00:00:00

abstract：INTRODUCTION:Video-assisted thoracic surgery (VATS) lung resections are complex procedures with a critical role played by endoscopic staplers in the transection of vessels, bronchi, and lung tissue. This retrospective, observational study compared hospital resource use, costs, and complications of VATS lobectomy proced...

journal_title：Advances in therapy

authors： Miller DL,Roy S,Kassis ES,Yadalam S,Ramisetti S,Johnston SS

更新日期：2018-05-01 00:00:00

abstract：:This study was performed to investigate the relationships between markers of inflammation in serum (interleukin-6 [IL-6], interleukin-10 [IL-10], and granulocyte elastase [GE]), severity of injury, and clinical outcomes, and to evaluate the predictive value of these markers for major complications and mortality. This ...

journal_title：Advances in therapy

authors： Akkose S,Ozgurer A,Bulut M,Koksal O,Ozdemír F,Ozguç H

更新日期：2007-09-01 00:00:00

abstract：INTRODUCTION:A combination of magnetic resonance imaging (MRI) with real-time high-resolution ultrasound (US) known as fusion imaging may improve visualization of musculoskeletal (MSK) sports medicine injuries. The aim of this study was to evaluate the applicability of MRI-US fusion technology in MSK sports medicine. ...

journal_title：Advances in therapy

authors： Wong-On M,Til-Pérez L,Balius R

更新日期：2015-06-01 00:00:00

abstract：INTRODUCTION:Idiopathic pulmonary fibrosis (IPF) is the classic progressive fibrosing interstitial lung disease (ILD), but some patients with ILDs other than IPF also develop a progressive fibrosing phenotype (PF-ILD). Information on use and cost of healthcare resources in patients with PF-ILD is limited. METHODS:We u...

journal_title：Advances in therapy

authors： Olson AL,Maher TM,Acciai V,Mounir B,Quaresma M,Zouad-Lejour L,Wells CD,De Loureiro L

更新日期：2020-07-01 00:00:00

abstract：:This prospective study was performed to determine whether gentamicin can be prescribed routinely to patients with spinal cord injury undergoing urologic procedures, or whether antibiotic therapy must be selected on the basis of recent urine microbiologic test results. Between January 2004 and June 2005, procedures wer...

journal_title：Advances in therapy

authors： Vaidyanathan S,Soni BM

更新日期：2006-01-01 00:00:00

abstract：:This 2-year prospective study was conducted to identify those at risk for ophthalmologic emergencies, to define the risk factors and reasons for eye injuries, to analyze treatment options, and to compare findings with those of previous studies. A total of 203 patients (74% male, mean age 27.3+/-13.9 y, 51% right eye i...

journal_title：Advances in therapy

authors： Oner A,Kekec Z,Karakucuk S,Ikizceli I,Sözüer EM

更新日期：2006-03-01 00:00:00

abstract：:This multicenter, double-masked, randomized, parallel-group study compared the efficacy and safety of ketorolac tromethamine 0.5% ophthalmic solution with levocabastine 0.05% and ketorolac tromethamine vehicle in patients with seasonal allergic conjunctivitis. One drop of ketorolac, levocabastine, or vehicle was insti...

journal_title：Advances in therapy

authors： Donshik PC,Pearlman D,Pinnas J,Raizman MB,Tauber J,Tinkelman D,Walters TR

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Adherence to disease-modifying therapies (DMTs) is essential for the reduction of multiple sclerosis (MS) progression and relapse. However, only limited data currently exist on the impact of treatment adherence on MS-related clinical and economic outcomes in the real world setting. OBJECTIVE:To assess the i...

journal_title：Advances in therapy

authors： Tan H,Cai Q,Agarwal S,Stephenson JJ,Kamat S

更新日期：2011-01-01 00:00:00

abstract：:Salivary gland carcinomas of the larynx are uncommon. Adenoid cystic carcinoma is the most prevalent type of salivary gland carcinoma in this region, although other histologies such as mucoepidermoid carcinoma and adenocarcinomas have been reported. These tumors may present with advanced-stage due to nonspecific sympt...

journal_title：Advances in therapy

authors： López F,Williams MD,Skálová A,Hellquist H,Suárez C,Nixon IJ,Rodrigo JP,Cardesa A,Strojan P,Quer M,Hunt JL,Rinaldo A,Ferlito A

更新日期：2017-04-01 00:00:00

abstract：INTRODUCTION:Arteriosclerosis obliterans (ASO) causes ischemic symptoms of the lower limbs, reducing quality of life (QOL), and has a poor prognosis. Early diagnosis and treatment are necessary. In this study, the effects of long-term administration of beraprost sodium (beraprost) to treat ASO were investigated. METHO...

journal_title：Advances in therapy

authors： Arai T

更新日期：2013-05-01 00:00:00

abstract：:Chronic constipation (CC) and irritable bowel syndrome with constipation (IBS-C) are common gastrointestinal (GI) disorders. Current treatment options, either prescription or nonprescription medications, have limited efficacy in a subset of patients. There is significant demand for more efficacious medications for the...

journal_title：Advances in therapy

authors： Vazquez-Roque MI,Bouras EP

更新日期：2013-03-01 00:00:00

abstract：INTRODUCTION:This trial was conducted to assess the long-term safety, efficacy, and benefit of early add-on of linagliptin to insulin in patients with type 2 diabetes mellitus (T2DM). METHODS:This trial enrolled 246 subjects. The subjects were randomized to the linagliptin group or the control group and were observed ...

journal_title：Advances in therapy

authors： Katsuno T,Shiraiwa T,Iwasaki S,Park H,Watanabe N,Kaneko S,Terasaki J,Hanafusa T,Imagawa A,Shimomura I,Ikegami H,Koyama H,Namba M,Miyagawa JI,TRUST2 study group.

更新日期：2021-01-28 00:00:00

abstract：:This 6-month randomized study evaluated the safety and efficacy of sibutramine in 57 overweight Hispanic patients with hypertension. Following a 2-week washout to confirm the diagnosis of hypertension, antihypertensive medication was adjusted to achieve a blood pressure less than 140/90 mm Hg before institution of eit...

journal_title：Advances in therapy

authors： Fanghänel G,Cortinas L,Sánchez-Reyes L,Gómez-Santos R,Campos-Franco E,Berber A

更新日期：2003-03-01 00:00:00

abstract：:Endocrine therapy (ET) is integral to the treatment of hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) metastatic breast cancer (MBC). Aromatase inhibitors (AIs; e.g., anastrozole, letrozole, exemestane), selective estrogen receptor modulators (e.g., tamoxifen), and the selec...

journal_title：Advances in therapy

authors： Nagaraj G,Ma CX

更新日期：2020-11-15 00:00:00

abstract：:Data from the Framingham Heart Study and risk-appraisal models were used to develop a Coronary Heart Disease (CHD) Risk Factor Calculator for early identification of high-risk individuals. The Calculator was tested at an employee health fair for a large northeastern US corporation. Of the 590 employees who registered ...

journal_title：Advances in therapy

authors： Day D

更新日期：2001-01-01 00:00:00

abstract：:Knee osteoarthritis (KOA) is the most common musculoskeletal disorder, especially in middle up to old age. KOA also results in many complications like changes in gait. Nowadays, changes in lifestyle and the reduced physical activity make people more vulnerable to KOA. Therefore, considering the increasing prevalence o...

journal_title：Advances in therapy

authors： Ganjeh S,Rezaeian ZS,Mostamand J

更新日期：2020-08-01 00:00:00

abstract：INTRODUCTION:This study aimed to compare the challenge of puncture and catheterization and the effect of postoperative analgesia of ultrasound-guided continuous thoracic paravertebral block and the continuous epidural analgesia in patients receiving thoracoscopic surgery for lung cancer. METHODS:One-hundred and fifty ...

journal_title：Advances in therapy

authors： Huang QW,Li JB,Huang Y,Zhang WQ,Lu ZW

更新日期：2020-09-01 00:00:00

abstract：INTRODUCTION:Aripiprazole and olanzapine are atypical antipsychotics. Both drugs can induce metabolic changes; however, the metabolic side effects produced by aripiprazole are more benign. The aim of the study was to evaluate if aripiprazole and olanzapine alter prolactin levels, lipid and glucose metabolism and hepati...

journal_title：Advances in therapy

authors： Koller D,Almenara S,Mejía G,Saiz-Rodríguez M,Zubiaur P,Román M,Ochoa D,Navares-Gómez M,Santos-Molina E,Pintos-Sánchez E,Abad-Santos F

更新日期：2020-12-05 00:00:00

abstract：INTRODUCTION:Asthma is associated with significant economic burden. Inhaled corticosteroid and long-acting beta2-agonist (ICS/LABA) combination therapies are considered mainstays of treatment. We describe real-world use of ICS/LABAs by comparing treatment persistence and adherence among patients with asthma in the Unit...

journal_title：Advances in therapy

authors： Parimi M,Svedsater H,Ann Q,Gokhale M,Gray CM,Hinds D,Nixon M,Boxall N

更新日期：2020-06-01 00:00:00

abstract：INTRODUCTION:The long-term safety of dimethyl fumarate (DMF) in patients with relapsing-remitting multiple sclerosis (RRMS) has been studied in mainly Caucasian patients. The present interim analysis aimed to evaluate the 72-week safety of DMF in Japanese patients with RRMS. METHODS:Safety data of Japanese subjects en...

journal_title：Advances in therapy

authors： Ochi H,Niino M,Onizuka Y,Hiramatsu K,Hase M,Yun J,Matta A,Torii S

更新日期：2018-10-01 00:00:00

abstract：:Human papillomavirus (HPV) infection is one of the most common sexually transmitted infections in adolescents. Such infection is associated with substantial health risks and is unpredictable in its resolution. Genital warts are the most common clinical manifestations of genital HPV infections. Most genital warts are c...

journal_title：Advances in therapy

authors： Leung AK,Kellner JD,Davies HD

更新日期：2005-05-01 00:00:00

abstract：OBJECTIVES:Because clinical guidelines do not offer clear recommendations for treatment options after discontinuing a tumor necrosis factor (TNF) blocker, this study evaluated treatment patterns within 360 days after discontinuation of TNF-blocker treatment. METHODS:The IMS LifeLink Health Plan Claims database was use...

journal_title：Advances in therapy

authors： Yeaw J,Watson C,Fox KM,Schabert VF,Goodman S,Gandra SR

更新日期：2014-04-01 00:00:00

abstract：INTRODUCTION:Tiotropium, a long-acting muscarinic antagonist, is approved for maintenance treatment of asthma in patients at least 6 years of age in the USA. We systematically reviewed published evidence on the efficacy and safety of 2.5 µg tiotropium Respimat® add-on therapy to inhaled corticosteroid (ICS) with or wit...

journal_title：Advances in therapy

authors： Mansfield L,Duong-Quy S,Craig T

更新日期：2019-10-01 00:00:00