Impact of Powered and Tissue-Specific Endoscopic Stapling Technology on Clinical and Economic Outcomes of Video-Assisted Thoracic Surgery Lobectomy Procedures: A Retrospective, Observational Study.

abstract：INTRODUCTION:The findings of many new cardiology clinical trials over the last year have been published or presented at major international meetings. This paper aims to describe and place in context a summary of the key clinical trials in cardiology presented between January and December 2016. METHODS:The authors revi...

journal_title：Advances in therapy

authors： Gray A,McQuillan C,Menown IBA

更新日期：2017-07-01 00:00:00

abstract：:There has been increased interest in gout in both academic and clinical practice settings. Several reasons may explain this. The prevalence of both hyperuricemia and gout has risen in the last decades in developed countries and therefore the burden of gout has increased. The association of hyperuricemia and gout with ...

journal_title：Advances in therapy

authors： Perez-Ruiz F,Dalbeth N,Bardin T

更新日期：2015-01-01 00:00:00

abstract：:In a randomized, controlled, double-blind trial, 70 patients (mean age, 49.7 years) suffering from mild to moderate depression received one tablet of either St. John's Wort (Hypericum perforatum) extract (Calmigen) or fluoxetine hydrochloride (Prozac) twice a day for 6 weeks. Efficacy was determined according to the 1...

journal_title：Advances in therapy

authors： Behnke K,Jensen GS,Graubaum HJ,Gruenwald J

更新日期：2002-01-01 00:00:00

abstract：INTRODUCTION:There is limited information published on switching erythropoiesis-stimulating agent (ESA) treatment for anemia associated with chronic kidney disease (CKD) from darbepoetin alfa (DA) to methoxy polyethylene glycol-epoetin beta (PEG-Epo) outside the protocol of interventional clinical studies. AFFIRM (Aran...

journal_title：Advances in therapy

authors： Choi P,Farouk M,Manamley N,Addison J

更新日期：2013-11-01 00:00:00

abstract：:The aims of this study were to determine whether the nursing costs of functional disability could be assessed retrospectively and, if so, whether this method was sensitive enough to show the influence of a treatment on economic costs. Four studies were available for this purpose: three randomized, double-blind, place...

journal_title：Advances in therapy

authors： Vlietinck R,Van Loon H,Van de Broele H,Tormans G

更新日期：1993-09-01 00:00:00

abstract：INTRODUCTION:New inhalers propelled by hydrofluoroalkanes (HFAs) have improved plume characteristics: higher fine particle fraction, and warmer plumes with reduced force and velocity. Together, this may avoid reflex interruption of inhalation and improve lung deposition of the inhaled drugs. However, even with HFA-prop...

journal_title：Advances in therapy

authors： Johal B,Murphy S,Tuohy J,Marshall J

更新日期：2015-06-01 00:00:00

abstract：:Some patients with interstitial lung diseases (ILDs) other than idiopathic pulmonary fibrosis exhibit a progressive clinical phenotype. These chronic progressive fibrosing ILDs have a variety of underlying diseases, and their prevalence is currently unknown. Here we carry out the first systematic review of literature ...

journal_title：Advances in therapy

authors： Olson A,Hartmann N,Patnaik P,Wallace L,Schlenker-Herceg R,Nasser M,Richeldi L,Hoffmann-Vold AM,Cottin V

更新日期：2020-12-14 00:00:00

abstract：BACKGROUND:Naproxen is an NSAID with documented efficacy in pain management; however, it is associated with serious dose-related adverse events. A lower-dose naproxen drug product with comparable efficacy to commercially available naproxen could address these concerns. We studied the efficacy and safety of naproxen sub...

journal_title：Advances in therapy

authors： Young CL,Strand V,Altman R,Daniels S

更新日期：2013-10-01 00:00:00

abstract：INTRODUCTION:This clinical study aimed to investigate the effect of brinzolamide, a topical carbonic anhydrase inhibitor, on corneal endothelial cells (CECs) in patients with glaucoma using a follow-up clinical study design. METHODS:Patients with primary open-angle glaucoma or ocular hypertension were administrated an...

journal_title：Advances in therapy

authors： Nakano T,Inoue R,Kimura T,Suzumura H,Tanino T,Yamazaki Y,Yoshikawa K,Tatemichi M

更新日期：2016-08-01 00:00:00

abstract：INTRODUCTION:Osteoarthritis is a chronic rheumatoid disease mediated by metalloproteinases and inflammatory cytokines. Methylsulfonylmethane (MSM) and boswellic acids (BA) each show promise in the treatment of inflammatory processes, but the efficacy of combined treatment with these substances in the treatment of arthr...

journal_title：Advances in therapy

authors： Notarnicola A,Tafuri S,Fusaro L,Moretti L,Pesce V,Moretti B

更新日期：2011-10-01 00:00:00

abstract：:Real-world studies have become increasingly important in providing evidence of treatment effectiveness in clinical practice. While randomized clinical trials (RCTs) are the "gold standard" for evaluating the safety and efficacy of new therapeutic agents, necessarily strict inclusion and exclusion criteria mean that tr...

journal_title：Advances in therapy

authors： Blonde L,Khunti K,Harris SB,Meizinger C,Skolnik NS

更新日期：2018-11-01 00:00:00

abstract：:Available data from comparative trials involving 483 patients were analyzed to determine the rate of infectious morbidity following the use of absorbable staples versus traditional incision and suturing of the vaginal cuff in abdominal hysterectomy. Infections occurred in 24 of 268 (9%) patients who received absorbab...

journal_title：Advances in therapy

authors： Martens MG,Shailer LD

更新日期：1991-05-01 00:00:00

abstract：INTRODUCTION:Randomized controlled trials and real-world data from the USA have shown similar glycemic control with insulin glargine 300 U/ml (Gla-300) and insulin glargine 100 U/ml (Gla-100) and reduced hypoglycemia risk with Gla-300. This real-world study describes the efficacy and safety of Gla-300 and Gla-100 in pa...

journal_title：Advances in therapy

authors： Escalada J,Bonnet F,Wu J,Bonnemaire M,Gupta S,Cambron-Mellott JM,Nicholls C,Müller-Wieland D

更新日期：2020-09-01 00:00:00

abstract：:Recently, high levels of neurotrophic factors have been found in bronchial asthma; these factors include nerve growth factor, brain-derived neurotrophic factor, and leukemia inhibitory factor, among others. Neurotrophic factors are first synthesized in bronchial epithelial cells, immune cells, and other cells in the a...

journal_title：Advances in therapy

authors： Feng JT,Hu CP,Li XZ

更新日期：2007-05-01 00:00:00

abstract：:This 4-week double-blind, placebo-controlled study assessed the efficacy of impulse magnetic-field therapy for insomnia. One hundred one patients were randomly assigned to either active treatment (n = 50) or placebo (n = 51) and allocated to one of three diagnostic groups: (1) sleep latency; (2) interrupted sleep; or ...

journal_title：Advances in therapy

authors： Pelka RB,Jaenicke C,Gruenwald J

更新日期：2001-07-01 00:00:00

abstract：:The origin of chronic periodontal disease is strongly related to the nature and physiology of the subgingival bacterial biofilm, of which Porphyromonas gingivalis is a main protagonist. This study was conducted in vitro, to test the susceptibility of the W83 strain of P gingivalis to several oral antiseptics, bearing ...

journal_title：Advances in therapy

authors： Bercy P,Lasserre J

更新日期：2007-11-01 00:00:00

abstract：:Convergent evidence indicates that abnormalities in the innate immune system may be pertinent to the pathogenesis, phenomenology, and possible treatment of several mental disorders. In keeping with this view, the targeting of interleukin-6 with the human monoclonal antibody sirukumab may represent a possible treatment...

journal_title：Advances in therapy

authors： Zhou AJ,Lee Y,Salvadore G,Hsu B,Fonseka TM,Kennedy SH,McIntyre RS

更新日期：2017-01-01 00:00:00

abstract：INTRODUCTION:Type 2 diabetes mellitus (T2DM) is a complex disease in which multiple organs and hormones contribute to the pathogenesis of disease. The intestinal hormone, glucagon-like peptide-1 (GLP-1), secreted in response to nutrient ingestion, increases insulin secretion from pancreatic β-cells and reduces glucagon...

journal_title：Advances in therapy

authors： Jain R

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak is a serious health concern. Repurposing of existing drugs indicated for other conditions seems to be the first choice for immediate therapeutic management. The quality of early evidence favoring the different treatment options needs t...

journal_title：Advances in therapy

authors： Subramanian K,Nalli A,Senthil V,Jain S,Nayak A,Bhat A

更新日期：2020-10-01 00:00:00

abstract：:The aim of this prospective, randomized, open-label, blinded endpoint (PROBE) study was to compare the antihypertensive efficacy of 2 angiotensin II (AII) receptor antagonists with different pharmacologic profiles, valsartan and olmesartan, in patients with mild-to-moderate essential hypertension. After an initial 2-w...

journal_title：Advances in therapy

authors： Destro M,Scabrosetti R,Vanasia A,Mugellini A

更新日期：2005-01-01 00:00:00

abstract：:Nateglinide is an oral antidiabetic medication that acts through rapid, short-term stimulation of insulin production. This study was undertaken to identify the incidence and nature of adverse effects of nateglinide and to assess its efficacy in clinical practice. Patients (n = 3254) were recruited from 606 centers in ...

journal_title：Advances in therapy

authors： Taki H,Maki T,Iso T,Iwamoto K,Kajiura T

更新日期：2005-09-01 00:00:00

abstract：INTRODUCTION:Spinal muscular atrophy (SMA) is a neurodegenerative disease of the motor neurons that results in progressive muscle weakness. It is also the leading hereditary cause of infant mortality. Homozygous loss of the survival motor neuron (SMN1) gene causes SMA, and the number of copies of the SMN2 gene modulate...

journal_title：Advances in therapy

authors： Dayangaç-Erden D,Topaloğlu H,Erdem-Yurter H

更新日期：2008-03-01 00:00:00

abstract：INTRODUCTION:This pooled analysis of data from three phase 3 studies in patients with chronic osteoarthritis knee or low back pain evaluated the efficacy and tolerability of tapentadol prolonged release (PR; 100-250 mg twice daily) compared with placebo and oxycodone hydrochloride (HCl) controlled release (CR; 20-50 mg...

journal_title：Advances in therapy

authors： Lange B,Kuperwasser B,Okamoto A,Steup A,Häufel T,Ashworth J,Etropolski M

更新日期：2010-06-01 00:00:00

abstract：:Endocrine therapy (ET) is integral to the treatment of hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) metastatic breast cancer (MBC). Aromatase inhibitors (AIs; e.g., anastrozole, letrozole, exemestane), selective estrogen receptor modulators (e.g., tamoxifen), and the selec...

journal_title：Advances in therapy

authors： Nagaraj G,Ma CX

更新日期：2020-11-15 00:00:00

abstract：INTRODUCTION:Recent research has suggested that serum tumor markers can give valuable prognostic information in gastric cancer. In this study, we examined the relationship between preoperative serum carcinoembryonic antigen (CEA), carbohydrate antigen (CA) 19-9, CA 72-4, and alfa fetoprotein (AFP) levels on clinicopath...

journal_title：Advances in therapy

authors： Ucar E,Semerci E,Ustun H,Yetim T,Huzmeli C,Gullu M

更新日期：2008-10-01 00:00:00

abstract：INTRODUCTION:To date, no study has reported the prevalence of cannabis use in chronic pain patients. The aim of this study is to investigate the trends in cannabis use among chronic pain in-patients from 2011 to 2015 in the USA. METHODS:Patients were identified from the National Inpatient Sample (NIS) database using t...

journal_title：Advances in therapy

authors： Orhurhu V,Urits I,Olusunmade M,Olayinka A,Salisu Orhurhu M,Uwandu C,Aner M,Ogunsola S,Akpala L,Hirji S,Viswanath O,Karri J,Simopoulos T,Gill J

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:It is hypothesized that diabetes mellitus (DM) and mood disorders share points of pathophysiological commonality in the central nervous system. METHODS:A PubMed search of all English-language articles published between 1966 and March 2009 was performed with the following search terms: depression, mood disor...

journal_title：Advances in therapy

authors： McIntyre RS,Kenna HA,Nguyen HT,Law CW,Sultan F,Woldeyohannes HO,Adams AK,Cheng JS,Lourenco M,Kennedy SH,Rasgon NL

更新日期：2010-02-01 00:00:00

abstract：INTRODUCTION:To evaluate, from the patient's perspective, the burden of pain associated with hip/knee osteoarthritis (OA) in the USA and selected European Union (EU) countries. METHODS:Data were drawn from the 2017 global Adelphi OA Disease Specific Programme™ (DSP). Patients with hip/knee OA were stratified based on ...

journal_title：Advances in therapy

authors： Jackson J,Iyer R,Mellor J,Wei W

更新日期：2020-09-01 00:00:00

abstract：:This study was undertaken to evaluate the ocular hypotensive efficacy of brimonidine Purite 0.15% (Alphagan P 0.15%; Allergan, Inc., Irvine, Calif) given as adjunctive therapy with latanoprost 0.005% (Xalatan; Pfizer Inc., New York, NY( to patients with open-angle glaucoma or ocular hypertension. In this multicenter, ...

journal_title：Advances in therapy

authors： Mundorf T,Noecker RJ,Earl M

更新日期：2007-03-01 00:00:00

abstract：INTRODUCTION:It is unclear whether patients and their loved ones appreciate that cardiovascular disease (CVD) is the major cause of morbidity and mortality in type 2 diabetes mellitus (T2DM). The purpose of this survey was to evaluate the degree of awareness regarding the link between T2DM and CVD. METHODS:An online s...

journal_title：Advances in therapy

authors： Perreault L,Boardman MK,Pak J

更新日期：2019-03-01 00:00:00