Retrospective estimate of the nursing cost of autonomy impairment and cost benefit in clinical trials: feasibility and application of piracetam in demented elderly patients.

abstract：:The single-tablet combination of vildagliptin and metformin addresses key defects of type 2 diabetes for improved glycemic control. By inhibiting the dipeptidyl peptidase-4 (DPP-4) enzyme, vildagliptin raises the levels of the active incretin hormones, glucagon-like peptide 1 and glucose-dependent insulinotropic pepti...

journal_title：Advances in therapy

authors： Tahrani AA,Piya MK,Barnett AH

更新日期：2009-02-01 00:00:00

abstract：INTRODUCTION:Asthma is associated with significant economic burden. Inhaled corticosteroid and long-acting beta2-agonist (ICS/LABA) combination therapies are considered mainstays of treatment. We describe real-world use of ICS/LABAs by comparing treatment persistence and adherence among patients with asthma in the Unit...

journal_title：Advances in therapy

authors： Parimi M,Svedsater H,Ann Q,Gokhale M,Gray CM,Hinds D,Nixon M,Boxall N

更新日期：2020-06-01 00:00:00

abstract：:Retinal vein occlusions are common retinal vascular disorders with the potential for significant vision-related morbidity. Retinal vein occlusions are classified as either branch retinal vein occlusion (BRVO), central retinal vein occlusion (CRVO), or hemiretinal vein occlusion (HRVO) based on the specific occlusion s...

journal_title：Advances in therapy

authors： Aref AA,Scott IU

更新日期：2011-01-01 00:00:00

abstract：:Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19), which can induce multisystem disease. Human angiotensin-converting enzyme 2 (ACE2) widely expressing in arterial and venous endothelial cells and arterial smooth muscle cells has been identified as a functional rec...

journal_title：Advances in therapy

authors： Wang J,Saguner AM,An J,Ning Y,Yan Y,Li G

更新日期：2020-07-01 00:00:00

abstract：INTRODUCTION:Wet age-related macular degeneration (AMD) is a chronic eye condition that causes severe deterioration of vision and even blindness. Current wet AMD treatment in the UK involves the vascular endothelial growth factor inhibitors ranibizumab and aflibercept. Patients with wet AMD require frequent and long-te...

journal_title：Advances in therapy

authors： Ghosh W,Wickstead R,Claxton L,Kusel J,Taylor M,Fleetwood K,Pulikottil-Jacob R

更新日期：2016-09-01 00:00:00

abstract：:The prevalence of chronic airways diseases such as chronic obstructive pulmonary disease and asthma is increasing. They lead to symptoms such as a cough and shortness of breath, partially through bronchoconstriction. Inhaled anticholinergics are one of a number of treatments designed to treat bronchoconstriction in ai...

journal_title：Advances in therapy

authors： Flynn RA,Glynn DA,Kennedy MP

更新日期：2009-10-01 00:00:00

abstract：PURPOSE:To compare the efficacy of bromfenac 0.09% and dexamethasone 0.1% in the treatment of anterior chamber inflammation after uncomplicated cataract surgery. METHODS:Seventy-six patients with senile cataracts and no other ocular comorbidities who underwent uneventful phacoemulsification were randomized 1:1 to rece...

journal_title：Advances in therapy

authors： Coassin M,De Maria M,Mastrofilippo V,Braglia L,Cimino L,Sartori A,Fontana L

更新日期：2019-10-01 00:00:00

abstract：:Permixon, the lipidosterolic extract of Serenoa repens, is widely used for the treatment of symptoms associated with benign prostatic hyperplasia (BPH). This open study assessed the efficacy and tolerability of Permixon 160 mg twice daily administered for 2 years. One hundred fifty-five men with clinically diagnosed B...

journal_title：Advances in therapy

authors： Pytel YA,Vinarov A,Lopatkin N,Sivkov A,Gorilovsky L,Raynaud JP

更新日期：2002-11-01 00:00:00

abstract：:This prospective study was performed to determine whether gentamicin can be prescribed routinely to patients with spinal cord injury undergoing urologic procedures, or whether antibiotic therapy must be selected on the basis of recent urine microbiologic test results. Between January 2004 and June 2005, procedures wer...

journal_title：Advances in therapy

authors： Vaidyanathan S,Soni BM

更新日期：2006-01-01 00:00:00

abstract：:Knee osteoarthritis (KOA) is the most common musculoskeletal disorder, especially in middle up to old age. KOA also results in many complications like changes in gait. Nowadays, changes in lifestyle and the reduced physical activity make people more vulnerable to KOA. Therefore, considering the increasing prevalence o...

journal_title：Advances in therapy

authors： Ganjeh S,Rezaeian ZS,Mostamand J

更新日期：2020-08-01 00:00:00

abstract：:Despite the results from clinical trials in patients with hypertension and the development of a long list of guidelines for the management of hypertension, many physicians and other healthcare professionals still manage hypertension using approaches that clearly diverge at least partially from the recommendations of t...

journal_title：Advances in therapy

authors： Malacco E,Ferri C,Grandi AM,Kilama MO,Soglian AG,Vigna L

更新日期：2005-03-01 00:00:00

abstract：:Designed to provide information about patients with schizophrenia who switch from depot neuroleptics to the oral, atypical antipsychotic risperidone, this multicenter observational study enrolled patients who wished to stop the depot, had an unsatisfactory response, or experienced unacceptable side effects. Individual...

journal_title：Advances in therapy

authors： Desai NM,Huq Z,Martin SD,McDonald G

更新日期：1999-03-01 00:00:00

abstract：:This study was conducted to assess clinical and cost outcomes associated with the use of daptomycin. This objective was addressed through a consecutive patient chart review of the first 50 inpatients treated with daptomycin. Type of infection, identity of isolated pathogens, prior therapy, duration of therapy, length ...

journal_title：Advances in therapy

authors： Fossaceca C

更新日期：2007-05-01 00:00:00

abstract：:In this 2-week, randomized, crossover study, ophthalmic solutions of nedocromil sodium 2% and olopatadine hydrochloride 0.1% were compared for effectiveness and acceptability in 28 patients with perennial allergic conjunctivitis and previous olopatadine experience. Patients received nedocromil twice daily or olopatadi...

journal_title：Advances in therapy

authors： Alexander M,Allegro S,Hicks A

更新日期：2000-05-01 00:00:00

abstract：:Convergent evidence indicates that abnormalities in the innate immune system may be pertinent to the pathogenesis, phenomenology, and possible treatment of several mental disorders. In keeping with this view, the targeting of interleukin-6 with the human monoclonal antibody sirukumab may represent a possible treatment...

journal_title：Advances in therapy

authors： Zhou AJ,Lee Y,Salvadore G,Hsu B,Fonseka TM,Kennedy SH,McIntyre RS

更新日期：2017-01-01 00:00:00

abstract：INTRODUCTION:Crohn's disease (CD) is a chronic inflammatory disease of the gastrointestinal tract. This real-world study evaluated persistence, dose titration, health care resource utilization (HCRU) and associated costs, and medication use among CD patients treated with ustekinumab (UST) in several pooled US commercia...

journal_title：Advances in therapy

authors： Obando C,Ding Z,Muser E,Vaidya N,Qiang W,Sun X,Wang H,Mallampati R,Xie L

更新日期：2020-05-01 00:00:00

abstract：INTRODUCTION:Acute gastrointestinal bleeding (GIB) is a major cause of death in liver cirrhosis. This multicenter study aims to develop and validate a novel and easy-to-access model for predicting the prognosis of patients with cirrhosis and acute GIB. METHODS:Patients with cirrhosis and acute GIB were enrolled and ra...

journal_title：Advances in therapy

authors： Bai Z,Li B,Lin S,Liu B,Li Y,Zhu Q,Wu Y,Yang Y,Tang S,Meng F,Chen Y,Yuan S,Shao L,Qi X

更新日期：2019-11-01 00:00:00

abstract：:To avoid the side effects associated with long-term administration of high doses of inhaled glucocorticosteroids, they should be used at the lowest effective dose. This study compared the clinical efficacy of budesonide given via a dry-powder, inspiratory flow-driven device (Turbuhaler), at a daily dose of 800 microgr...

journal_title：Advances in therapy

authors： Piquet J,Zuck P,Dennewald G,Dugue P,Grivaux M,Brun P,Severac JC,Ostinelli J,Cheeseman KH

更新日期：1996-01-01 00:00:00

abstract：INTRODUCTION:Benign prostatic hyperplasia (BPH) is commonly treated with 5-alpha-reductase inhibitor/alpha blocker combination therapy or with alpha blocker monotherapy. However, in China, the characteristics of BPH patients receiving 5-alpha-reductase inhibitor/alpha blocker combination therapy or alpha blocker monoth...

journal_title：Advances in therapy

authors： Fu Y,Han S,Wang L,Gao W,Wu E,Cao X,Wang J

更新日期：2018-08-01 00:00:00

abstract：INTRODUCTION:To date, no study has reported the prevalence of cannabis use in chronic pain patients. The aim of this study is to investigate the trends in cannabis use among chronic pain in-patients from 2011 to 2015 in the USA. METHODS:Patients were identified from the National Inpatient Sample (NIS) database using t...

journal_title：Advances in therapy

authors： Orhurhu V,Urits I,Olusunmade M,Olayinka A,Salisu Orhurhu M,Uwandu C,Aner M,Ogunsola S,Akpala L,Hirji S,Viswanath O,Karri J,Simopoulos T,Gill J

更新日期：2020-08-01 00:00:00

abstract：INTRODUCTION:Healthy eating is a critical aspect of the prevention and management of type 2 diabetes (T2DM). Disrupted eating patterns can result in poor glucose control and increase the likelihood of diabetic complications. Teneligliptin inhibits dipeptidyl peptidase-4 activity for 24 h and suppresses postprandial hyp...

journal_title：Advances in therapy

authors： Kadowaki T,Haneda M,Ito H,Sasaki K,Hiraide S,Matsukawa M,Ueno M

更新日期：2018-06-01 00:00:00

abstract：INTRODUCTION:To evaluate long-term outcomes following stand-alone implantation of two second-generation trabecular micro-bypass stents (iStent inject®, Glaukos Corp., San Clemente, CA, USA) in eyes with predominantly primary open-angle glaucoma (POAG) and considerable preoperative disease burden. METHODS:Eyes with POA...

journal_title：Advances in therapy

authors： Hengerer FH,Auffarth GU,Riffel C,Conrad-Hengerer I

更新日期：2019-07-01 00:00:00

abstract：INTRODUCTION:New biosimilars of monoclonal antibodies are anticipated to bring significant cost savings and increase access to treatment. The rituximab biosimilar CT-P10 has recently been approved in Europe in all indications held by reference rituximab (RTX), including rheumatoid arthritis, non-Hodgkin's lymphoma, and...

journal_title：Advances in therapy

authors： Gulácsi L,Brodszky V,Baji P,Rencz F,Péntek M

更新日期：2017-05-01 00:00:00

abstract：INTRODUCTION:Little has been published on respiratory syncytial virus (RSV) among Medicare patients at high risk (HR) of RSV complications due to age or comorbidity. METHODS:Adult patients (at least 18 years of age) with at least 1 diagnostic code for RSV were identified using the 5% US Medicare database from 2011 thr...

journal_title：Advances in therapy

authors： Wyffels V,Kariburyo F,Gavart S,Fleischhackl R,Yuce H

更新日期：2020-03-01 00:00:00

abstract：INTRODUCTION:Partial nephrectomy (PN) has evolved into the surgical standard of care for localized renal lesions. Hemostatic agents (HA) support the surgeon in achieving local hemostasis during PN. We previously reported initial results with the HA Hemopatch® in PN. We now report our experiences with Hemopatch® in a la...

journal_title：Advances in therapy

authors： Hupe MC,Büttner M,Tabrizi PF,Merseburger AS,Kuczyk MA,Imkamp F

更新日期：2020-12-04 00:00:00

abstract：INTRODUCTION:Claims data (IBM MarketScan Commercial and MarketScan Medicare Supplemental databases) from June 30, 2011 to September 30, 2017 were used to evaluate the cost impact of human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer (MBC) in this retrospective cohort study. METHODS:The p...

journal_title：Advances in therapy

authors： Sussell JA,Sheinson D,Wu N,Shah-Manek B,Seetasith A

更新日期：2020-04-01 00:00:00

abstract：INTRODUCTION:Repository corticotropin injection (RCI; H.P. Acthar® Gel; Mallinckrodt Pharmaceuticals Inc., Hampton, NJ) is a highly purified, prolonged-release porcine preparation of adrenocorticotropic hormone (ACTH) analogue that is FDA-approved for treatment of 19 autoimmune and inflammatory disorders. The diverse p...

journal_title：Advances in therapy

authors： Philbin M,Niewoehner J,Wan GJ

更新日期：2017-08-01 00:00:00

abstract：:Adenoid cystic carcinoma (AdCC) of the head and neck is a well-recognized pathologic entity that rarely occurs in the larynx. Although the 5-year locoregional control rates are high, distant metastasis has a tendency to appear more than 5 years post treatment. Because AdCC of the larynx is uncommon, it is difficult to...

journal_title：Advances in therapy

authors： Coca-Pelaz A,Barnes L,Rinaldo A,Cardesa A,Shah JP,Rodrigo JP,Suárez C,Eloy JA,Bishop JA,Devaney KO,Thompson LD,Wenig BM,Strojan P,Hamoir M,Bradley PJ,Gnepp DR,Silver CE,Slootweg PJ,Triantafyllou A,Vander Poorten V,

更新日期：2016-04-01 00:00:00

abstract：INTRODUCTION:Subsequent lines of subcutaneous tumor necrosis factor alpha inhibitor (SC-TNFi) treatment may be well motivated in the management of rheumatoid arthritis (RA), ankylosing spondylitis (AS), and psoriatic arthritis (PsA)-collectively named inflammatory arthritis (IA). However, the costs associated with swit...

journal_title：Advances in therapy

authors： Dalén J,Luttropp K,Svedbom A,Black CM,Kachroo S

更新日期：2020-09-01 00:00:00

abstract：:This study was performed to investigate the relationships between markers of inflammation in serum (interleukin-6 [IL-6], interleukin-10 [IL-10], and granulocyte elastase [GE]), severity of injury, and clinical outcomes, and to evaluate the predictive value of these markers for major complications and mortality. This ...

journal_title：Advances in therapy

authors： Akkose S,Ozgurer A,Bulut M,Koksal O,Ozdemír F,Ozguç H

更新日期：2007-09-01 00:00:00