Persistence and Adherence to ICS/LABA Drugs in UK Patients with Asthma: A Retrospective New-User Cohort Study.

abstract：INTRODUCTION:The aim of this study was to evaluate the effectiveness of re-education in the insulin injection technique for glycemic control. METHODS:A preliminary experimental study was performed with 87 insulin-treated diabetic outpatients (11 with type 1 diabetes, 76 with type 2 diabetes; 43 men, 44 women). All pat...

journal_title：Advances in therapy

authors： Nakatani Y,Matsumura M,Monden T,Aso Y,Nakamoto T

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:It is hypothesized that diabetes mellitus (DM) and mood disorders share points of pathophysiological commonality in the central nervous system. METHODS:A PubMed search of all English-language articles published between 1966 and March 2009 was performed with the following search terms: depression, mood disor...

journal_title：Advances in therapy

authors： McIntyre RS,Kenna HA,Nguyen HT,Law CW,Sultan F,Woldeyohannes HO,Adams AK,Cheng JS,Lourenco M,Kennedy SH,Rasgon NL

更新日期：2010-02-01 00:00:00

abstract：:This study was undertaken to evaluate the effectiveness of prophylactic intranasal mupirocin for peritonitis in patients on continuous ambulatory peritoneal dialysis (CAPD). A total of 49 patients undergoing CAPD for at least 6 mo were followed for 1 year. A nasal smear was obtained from each patient at the beginning ...

journal_title：Advances in therapy

authors： Sit D,Kadiroglu AK,Kayabasi H,Yilmaz ME

更新日期：2007-03-01 00:00:00

abstract：INTRODUCTION:To assess the impact of certolizumab pegol (CZP) treatment on clinical, patient-reported, and musculoskeletal ultrasound outcomes and to determine the treatment response time point most predictive of long-term outcomes in Italian patients with rheumatoid arthritis (RA). METHODS:CZP-SPEED (NCT01443364) was...

journal_title：Advances in therapy

authors： Sarzi-Puttini P,Filippucci E,Adami S,Meroni PL,Batticciotto A,Idolazzi L,De Lucia O,Talavera P,Kumke T,Grassi W

更新日期：2018-08-01 00:00:00

abstract：INTRODUCTION:It is unclear whether patients and their loved ones appreciate that cardiovascular disease (CVD) is the major cause of morbidity and mortality in type 2 diabetes mellitus (T2DM). The purpose of this survey was to evaluate the degree of awareness regarding the link between T2DM and CVD. METHODS:An online s...

journal_title：Advances in therapy

authors： Perreault L,Boardman MK,Pak J

更新日期：2019-03-01 00:00:00

abstract：:Data from the Framingham Heart Study and risk-appraisal models were used to develop a Coronary Heart Disease (CHD) Risk Factor Calculator for early identification of high-risk individuals. The Calculator was tested at an employee health fair for a large northeastern US corporation. Of the 590 employees who registered ...

journal_title：Advances in therapy

authors： Day D

更新日期：2001-01-01 00:00:00

abstract：INTRODUCTION:This retrospective study evaluates the efficacy of palliative chemotherapy with a modified docetaxel, cisplatin, 5-fluorouracil (5-FU; "TPF" regimen) regimen (mTPF; reduced doses of docetaxel, cisplatin, and 5-FU with reduction of intravenous 5-FU from 4 days to 2 days) in Asian patients with recurrent and...

journal_title：Advances in therapy

authors： Lin JT,Lai GM,Chang TH,Liu MT,Bi CP,Wang JW,Chen MK

更新日期：2012-01-01 00:00:00

abstract：INTRODUCTION:P-wave dispersion (PWD) has been shown to be a non-invasive electrocardiographic predictor for development of atrial fibrillation (AF). Thus, it may be possible to attenuate AF risk through improvement of PWD. In this study, we compared the effects of an angiotensin-converting enzyme (ACE) inhibitor, quina...

journal_title：Advances in therapy

authors： Guntekin U,Gunes Y,Tuncer M,Simsek H,Gunes A

更新日期：2008-08-01 00:00:00

abstract：:Salivary gland carcinomas of the larynx are uncommon. Adenoid cystic carcinoma is the most prevalent type of salivary gland carcinoma in this region, although other histologies such as mucoepidermoid carcinoma and adenocarcinomas have been reported. These tumors may present with advanced-stage due to nonspecific sympt...

journal_title：Advances in therapy

authors： López F,Williams MD,Skálová A,Hellquist H,Suárez C,Nixon IJ,Rodrigo JP,Cardesa A,Strojan P,Quer M,Hunt JL,Rinaldo A,Ferlito A

更新日期：2017-04-01 00:00:00

abstract：INTRODUCTION:To compare the 24-h intraocular pressure (IOP) control and tolerability of travoprost/timolol benzalkonium chloride (BAK)-free (TTFC) vs. latanoprost/timolol fixed combination preserved with BAK (LTFC) in open-angle glaucoma patients insufficiently controlled with latanoprost 0.005% monotherapy given once ...

journal_title：Advances in therapy

authors： Konstas AG,Voudouragkaki IC,Boboridis KG,Haidich AB,Paschalinou E,Giannopoulos T,Dragoumis ND,Makridis AK,Kahook MY

更新日期：2014-06-01 00:00:00

abstract：INTRODUCTION:The purpose of the study was to conduct a cost-effectiveness analysis and budget impact analysis comparing lopinavir with ritonavir (LPV/r) and atazanavir plus ritonavir (ATV+RTV) for antiretroviral-naïve patients with a baseline CD4+ T-cell distribution and total cholesterol (TC) profile as reported in th...

journal_title：Advances in therapy

authors： Simpson KN,Rajagopalan R,Dietz B

更新日期：2009-02-01 00:00:00

abstract：INTRODUCTION:Our objective was to determine the effectiveness of a perindopril/indapamide (Per/Ind) single-pill combination (SPC) in a broad range of patient profiles, including subgroups with varying hypertension severity, age and cardiovascular risk profiles. METHODS:Patient data from four large prospective observat...

journal_title：Advances in therapy

authors： Dézsi CA,Glezer M,Karpov Y,Brzozowska-Villatte R,Farsang C

更新日期：2020-11-05 00:00:00

abstract：:Multiple, potentially practice-changing cardiology trials have been presented or published over the past year. In this paper, we summarize and place in clinical context, new data regarding management of acute coronary syndrome and ST-elevation myocardial infarction (copeptin assessment, otamixaban, cangrelor, prasugre...

journal_title：Advances in therapy

authors： McNeice AH,McAleavey NM,Menown IB

更新日期：2014-08-01 00:00:00

abstract：INTRODUCTION:This Phase 2 clinical trial assessed the efficacy and safety of the novel antioxidative, renewable compound SkQ1 for topical treatment of dry eye signs and symptoms. METHODS:In a single-center, randomized, double-masked, placebo-controlled, 29-day study, 91 subjects with mild to moderate dry eye instilled...

journal_title：Advances in therapy

authors： Petrov A,Perekhvatova N,Skulachev M,Stein L,Ousler G

更新日期：2016-01-01 00:00:00

abstract：INTRODUCTION:Crohn's disease (CD) is a chronic inflammatory disease of the gastrointestinal tract. This real-world study evaluated persistence, dose titration, health care resource utilization (HCRU) and associated costs, and medication use among CD patients treated with ustekinumab (UST) in several pooled US commercia...

journal_title：Advances in therapy

authors： Obando C,Ding Z,Muser E,Vaidya N,Qiang W,Sun X,Wang H,Mallampati R,Xie L

更新日期：2020-05-01 00:00:00

abstract：:In the last few years, immunotherapy has transformed the way we treat solid tumors, including melanoma, lung, head neck, breast, renal, and bladder cancers. Durable responses and long-term survival benefit has been experienced by many cancer patients, with favorable toxicity profiles of immunotherapeutic agents relati...

journal_title：Advances in therapy

authors： Arora S,Velichinskii R,Lesh RW,Ali U,Kubiak M,Bansal P,Borghaei H,Edelman MJ,Boumber Y

更新日期：2019-10-01 00:00:00

abstract：INTRODUCTION:Diabetes-related healthcare costs are increasing in the United States, with inpatient hospitalization the largest component of medical expenditures. The aims of this study were to characterize hospitalized type 2 diabetes mellitus (T2DM) patients, understand the relationship between hospitalization and hea...

journal_title：Advances in therapy

authors： Saundankar V,Ellis J,Allen E,DeLuzio T,Moretz C,Meah Y,Suehs B,Bouchard J

更新日期：2015-07-01 00:00:00

abstract：INTRODUCTION:Well- or moderately differentiated gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are often slow-growing, and some patients with unresectable, asymptomatic, non-functioning tumors may face the choice between watchful waiting (WW), or somatostatin analogues (SSA) to delay progression. We developed ...

journal_title：Advances in therapy

authors： Wagner M,Samaha D,Khoury H,O'Neil WM,Lavoie L,Bennetts L,Badgley D,Gabriel S,Berthon A,Dolan J,Kulke MH,Goetghebeur M

更新日期：2018-01-01 00:00:00

abstract：INTRODUCTION:Most cases of small cell lung cancer (SCLC) are diagnosed at an advanced stage. The objective of this study was to investigate patient characteristics, survival, chemotherapy treatments, and health care use after a diagnosis of advanced SCLC in subjects enrolled in a health system network. METHODS:This wa...

journal_title：Advances in therapy

authors： He J,Shao C,Hui SL,Zhang Z,Baker J,Dexter PR,Kachroo S,Jin F

更新日期：2020-01-01 00:00:00

abstract：:Resistance to first- and second-generation anaplastic lymphoma kinase (ALK) tyrosine kinase inhibitors (TKIs) and development and progression of central nervous system metastases remain significant issues in the treatment of ALK-positive non-small-cell lung cancer. Lorlatinib is a novel third-generation ALK TKI that i...

journal_title：Advances in therapy

authors： Reed M,Rosales AS,Chioda MD,Parker L,Devgan G,Kettle J

更新日期：2020-06-01 00:00:00

abstract：OBJECTIVES:This study set out to examine the efficacy and tolerability of two innovative implant forms of leuprorelin acetate in men with advanced hormone-dependent prostate cancer in everyday clinical practice. METHODS:Data were collected from 818 patients (from 273 centers across Germany) who were pretreated with sl...

journal_title：Advances in therapy

authors： Gravel P,Samland D,Löffler M,Maier S,Panozzo M,Muenzberg M

更新日期：2013-03-01 00:00:00

abstract：INTRODUCTION:Adrenocortical carcinoma (ACC) is a rare malignancy with poor prognosis. It is vitally important to predict prognosis and restrict unnecessary adjuvant treatments for patients with ACC. This study aims to confirm the prognostic value of Ki-67 and provide a prognostic evaluation on ACC after primary surgery...

journal_title：Advances in therapy

authors： Zhang F,Zhang F,Liu Z,Wu K,Zhu Y,Lu Y

更新日期：2019-10-01 00:00:00

abstract：INTRODUCTION:The aim of this study was to assess the efficacy and safety of esomeprazole 40 mg once daily (q.d.) in healing reflux oesophagitis at 4 and 8 weeks, and the efficacy of esomeprazole 20 mg q.d. for 12 weeks in the maintenance of remission. METHODS:A total of 235 patients with endoscopically proven reflux o...

journal_title：Advances in therapy

authors： Atug O,Giral A,Kalayci C,Dolar E,Isitan F,Oguz D,Ovunc O,Ozgur O,Soykan I,Simsek I,Unal S,Yenice N,Turkish HEMANEX Study Group.

更新日期：2008-06-01 00:00:00

abstract：INTRODUCTION:Anti-vascular endothelial growth factor therapy is the standard of care for neovascular age-related macular degeneration (nAMD). The dosage of two licensed agents, ranibizumab and aflibercept, was established through clinical trials; however, it is unclear if either agent is administered as recommended in ...

journal_title：Advances in therapy

authors： Skelly A,Carius HJ,Bezlyak V,Chen FK

更新日期：2017-12-01 00:00:00

abstract：:Some patients with interstitial lung diseases (ILDs) other than idiopathic pulmonary fibrosis exhibit a progressive clinical phenotype. These chronic progressive fibrosing ILDs have a variety of underlying diseases, and their prevalence is currently unknown. Here we carry out the first systematic review of literature ...

journal_title：Advances in therapy

authors： Olson A,Hartmann N,Patnaik P,Wallace L,Schlenker-Herceg R,Nasser M,Richeldi L,Hoffmann-Vold AM,Cottin V

更新日期：2020-12-14 00:00:00

abstract：:This double-blind, randomized, prospective study was conducted to compare the analgesic and sedative efficacy of fentanyl and meperidine in orthopedic closed reduction of fractures and dislocations undertaken in the emergency department. Seventy consecutive adult patients with fractures or dislocations suitable for re...

journal_title：Advances in therapy

authors： Soysal S,Karcioglu O,Demircan A,Topacoglu H,Serinken M,Ozucelik N,Tirpan K,Gunerli A

更新日期：2004-09-01 00:00:00

abstract：INTRODUCTION:This study characterized the multidose pharmacokinetic (PK) characteristics of posaconazole tablets used as prophylactic antifungal therapy in Chinese patients with acute myelogenous leukemia (AML) at risk for invasive fungal infection (IFI). METHODS:Participants in this open-label, single-arm, phase 1b s...

journal_title：Advances in therapy

authors： Liu K,Wu D,Li J,Chen H,Ning H,Zhao T,Dai H,Chen L,Mangin E,Winchell GA,Waskin H,Jiang J,Qiu Y,Zhao XM

更新日期：2020-05-01 00:00:00

abstract：INTRODUCTION:One method of treatment for allergic diseases is allergen-specific immunotherapy (SIT). The clinical efficacy of SIT in pollen-induced allergic rhinitis has been demonstrated in several controlled clinical trials. There is no consensus about the protective effect of SIT. In this study, we evaluated the cor...

journal_title：Advances in therapy

authors： Ali I,Goksal K,Ozan B,Gulsen D

更新日期：2008-01-01 00:00:00

abstract：:X-linked hypophosphataemia (XLH) is the most prevalent form of hereditary rickets characterized by an alteration of phosphate metabolism which frequently leads to the appearance of fractures, bone deformities and growth delay. Although the mechanism of growth impairment in patients with XLH still needs to be clarified...

journal_title：Advances in therapy

authors： Santos Rodríguez F

更新日期：2020-05-01 00:00:00

abstract：INTRODUCTION:New biosimilars of monoclonal antibodies are anticipated to bring significant cost savings and increase access to treatment. The rituximab biosimilar CT-P10 has recently been approved in Europe in all indications held by reference rituximab (RTX), including rheumatoid arthritis, non-Hodgkin's lymphoma, and...

journal_title：Advances in therapy

authors： Gulácsi L,Brodszky V,Baji P,Rencz F,Péntek M

更新日期：2017-05-01 00:00:00