Efficacy and acceptability of nedocromil sodium 2% and olopatadine hydrochloride 0.1% in perennial allergic conjunctivitis.

abstract：:In order for the global healthcare system to remain sustainable, healthcare spending needs to be reduced, and self-treating certain conditions under the guidance of a pharmacist provides a means of accomplishing this goal. This article was developed to describe global healthcare trends affecting self-care with a speci...

journal_title：Advances in therapy

authors： Bell J,Dziekan G,Pollack C,Mahachai V

更新日期：2016-10-01 00:00:00

abstract：INTRODUCTION:The European Medicines Agency (EMA) requires vaccine manufacturers to conduct enhanced safety surveillance (ESS) of seasonal influenza vaccines including a near real-time evaluation of collected data. The objective was to identify whether the use of passive surveillance or active surveillance provides diff...

journal_title：Advances in therapy

authors： de Lusignan S,Dos Santos G,Byford R,Schuind A,Damaso S,Shende V,McGee C,Yonova I,Ferreira F

更新日期：2018-08-01 00:00:00

abstract：INTRODUCTION:Stimulant medications are the most effective drugs in the treatment of attention-deficit hyperactivity disorder (ADHD) in children and in adults. However, some patients do not respond to this treatment and other patients suffer from adverse effects. Very often there are also comorbid disorders that warrant...

journal_title：Advances in therapy

authors： Verbeeck W,Tuinier S,Bekkering GE

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Naproxen is an NSAID with documented efficacy in pain management; however, it is associated with serious dose-related adverse events. A lower-dose naproxen drug product with comparable efficacy to commercially available naproxen could address these concerns. We studied the efficacy and safety of naproxen sub...

journal_title：Advances in therapy

authors： Young CL,Strand V,Altman R,Daniels S

更新日期：2013-10-01 00:00:00

abstract：:Atrial fibrillation (AF) and venous thromboembolism (VTE) are highly prevalent and relevant healthcare issues. Direct oral anticoagulants (DOACs) are now the first-choice for anticoagulant treatment of these conditions displaying a better efficacy/safety profile than vitamin-K antagonists, mainly due to significantly ...

journal_title：Advances in therapy

authors： Ballestri S,Capitelli M,Fontana MC,Arioli D,Romagnoli E,Graziosi C,Lonardo A,Marietta M,Dentali F,Cioni G

更新日期：2020-05-01 00:00:00

abstract：INTRODUCTION:Claims data (IBM MarketScan Commercial and MarketScan Medicare Supplemental databases) from June 30, 2011 to September 30, 2017 were used to evaluate the cost impact of human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer (MBC) in this retrospective cohort study. METHODS:The p...

journal_title：Advances in therapy

authors： Sussell JA,Sheinson D,Wu N,Shah-Manek B,Seetasith A

更新日期：2020-04-01 00:00:00

abstract：:This multicenter, double-masked, randomized, parallel-group study compared the efficacy and safety of ketorolac tromethamine 0.5% ophthalmic solution with levocabastine 0.05% and ketorolac tromethamine vehicle in patients with seasonal allergic conjunctivitis. One drop of ketorolac, levocabastine, or vehicle was insti...

journal_title：Advances in therapy

authors： Donshik PC,Pearlman D,Pinnas J,Raizman MB,Tauber J,Tinkelman D,Walters TR

更新日期：2000-03-01 00:00:00

abstract：:Available data from comparative trials involving 483 patients were analyzed to determine the rate of infectious morbidity following the use of absorbable staples versus traditional incision and suturing of the vaginal cuff in abdominal hysterectomy. Infections occurred in 24 of 268 (9%) patients who received absorbab...

journal_title：Advances in therapy

authors： Martens MG,Shailer LD

更新日期：1991-05-01 00:00:00

abstract：:This 4-week double-blind, placebo-controlled study assessed the efficacy of impulse magnetic-field therapy for insomnia. One hundred one patients were randomly assigned to either active treatment (n = 50) or placebo (n = 51) and allocated to one of three diagnostic groups: (1) sleep latency; (2) interrupted sleep; or ...

journal_title：Advances in therapy

authors： Pelka RB,Jaenicke C,Gruenwald J

更新日期：2001-07-01 00:00:00

abstract：INTRODUCTION:Our objective was to determine the effectiveness of a perindopril/indapamide (Per/Ind) single-pill combination (SPC) in a broad range of patient profiles, including subgroups with varying hypertension severity, age and cardiovascular risk profiles. METHODS:Patient data from four large prospective observat...

journal_title：Advances in therapy

authors： Dézsi CA,Glezer M,Karpov Y,Brzozowska-Villatte R,Farsang C

更新日期：2020-11-05 00:00:00

abstract：INTRODUCTION:Transient hepatic attenuation differences (THAD) are areas of high parenchymal enhancement observed during the hepatic arterial phase on computed tomography (CT). THAD in the left lobe of the liver can lead to surgical complications. METHODS:A retrospective study was conducted on patients who underwent mu...

journal_title：Advances in therapy

authors： Yang B,Si G,He Q,Liu S,Wang S,Xian R,Zhang J,Yu F,Guan J

更新日期：2020-09-01 00:00:00

abstract：INTRODUCTION:Pulmonary arterial hypertension (PAH) is associated with poor prognosis despite significant recent advances in its treatment. An intravenous formulation of epoprostenol sodium containing glycine and mannitol (epoprostenol GM; GlaxoSmithKline, London, UK) is widely used to treat PAH. A new formulation of ep...

journal_title：Advances in therapy

authors： Tamura Y,Ono T,Fukuda K,Satoh T,Sasayama S

更新日期：2013-05-01 00:00:00

abstract：:Real-world studies have become increasingly important in providing evidence of treatment effectiveness in clinical practice. While randomized clinical trials (RCTs) are the "gold standard" for evaluating the safety and efficacy of new therapeutic agents, necessarily strict inclusion and exclusion criteria mean that tr...

journal_title：Advances in therapy

authors： Blonde L,Khunti K,Harris SB,Meizinger C,Skolnik NS

更新日期：2018-11-01 00:00:00

abstract：INTRODUCTION:Advances in cystic fibrosis (CF) therapy have resulted in improved survival and increasing treatment burden and costs. The economic impact of current treatment strategies for CF is poorly defined. METHODS:The authors prospectively assessed direct medical costs (including hospitalizations, outpatient inter...

journal_title：Advances in therapy

authors： Colombo C,Daccò V,Alicandro G,Loi S,Mazzi S,Lucioni C,Ravasio R

更新日期：2013-02-01 00:00:00

abstract：INTRODUCTION:Vitamin E is one of the most promising agents for nonalcoholic steatohepatitis (NASH) treatment, and its drug responsiveness may be closely associated with haptoglobin (Hp) genotype. However, its efficacy and safety remain unknown in China. This clinical trial of vitamin E versus placebo for the treatment ...

journal_title：Advances in therapy

authors： Zang S,Chen J,Song Y,Bai L,Chen J,Chi X,He F,Sheng H,Wang J,Xie S,Xie W,Yang Y,Zhang J,Zheng M,Zou Z,Wang B,Shi J,Chinese NAFLD Clinical Research Network (CNAFLD CRN).

更新日期：2018-02-01 00:00:00

abstract：INTRODUCTION:Data regarding the prevalence of immune thrombocytopenia (ITP) is limited, and is derived from North American population-based analyses. Therefore, the authors conducted the first study outside the United States (US) using the United Kingdom (UK) General Practice Research Database (GPRD) to estimate the ad...

journal_title：Advances in therapy

authors： Bennett D,Hodgson ME,Shukla A,Logie JW

更新日期：2011-12-01 00:00:00

abstract：:Fibroids, the most common tumor in women of reproductive age, impact negatively on women's health and quality of life, and have significant cost implications for their management. The current mainstay treatments are surgical (myomectomy and hysterectomy) and more recently radiological (UAE and focused ultrasound surge...

journal_title：Advances in therapy

authors： Talaulikar VS,Manyonda IT

更新日期：2012-08-01 00:00:00

abstract：INTRODUCTION:Randomized controlled trials and real-world data from the USA have shown similar glycemic control with insulin glargine 300 U/ml (Gla-300) and insulin glargine 100 U/ml (Gla-100) and reduced hypoglycemia risk with Gla-300. This real-world study describes the efficacy and safety of Gla-300 and Gla-100 in pa...

journal_title：Advances in therapy

authors： Escalada J,Bonnet F,Wu J,Bonnemaire M,Gupta S,Cambron-Mellott JM,Nicholls C,Müller-Wieland D

更新日期：2020-09-01 00:00:00

abstract：INTRODUCTION:This trial was conducted to assess the long-term safety, efficacy, and benefit of early add-on of linagliptin to insulin in patients with type 2 diabetes mellitus (T2DM). METHODS:This trial enrolled 246 subjects. The subjects were randomized to the linagliptin group or the control group and were observed ...

journal_title：Advances in therapy

authors： Katsuno T,Shiraiwa T,Iwasaki S,Park H,Watanabe N,Kaneko S,Terasaki J,Hanafusa T,Imagawa A,Shimomura I,Ikegami H,Koyama H,Namba M,Miyagawa JI,TRUST2 study group.

更新日期：2021-01-28 00:00:00

abstract：INTRODUCTION:Idiopathic pulmonary fibrosis (IPF) is the classic progressive fibrosing interstitial lung disease (ILD), but some patients with ILDs other than IPF also develop a progressive fibrosing phenotype (PF-ILD). Information on use and cost of healthcare resources in patients with PF-ILD is limited. METHODS:We u...

journal_title：Advances in therapy

authors： Olson AL,Maher TM,Acciai V,Mounir B,Quaresma M,Zouad-Lejour L,Wells CD,De Loureiro L

更新日期：2020-07-01 00:00:00

abstract：:In this double-blind, randomized, placebo-controlled, prospective study, the clinical efficacy and tolerability of oral Hypericum extract STW 3-VI (Laif) 900 mg once daily was compared with that of placebo. A total of 140 outpatients (94 women; 46 men) with moderate depressive disorders and a 17-item Hamilton Depressi...

journal_title：Advances in therapy

authors： Uebelhack R,Gruenwald J,Graubaum HJ,Busch R

更新日期：2004-07-01 00:00:00

abstract：INTRODUCTION:Respiratory tract infections are common, and these infections occur frequently in children, susceptible adults, and older persons. The risk for recurrences and complications relates not only to the presence of viruses but also to immune function. Therefore, modulation of the immune system and antiviral int...

journal_title：Advances in therapy

authors： Schapowal A,Klein P,Johnston SL

更新日期：2015-03-01 00:00:00

abstract：INTRODUCTION:This retrospective study used data from a primary care database to compare two insulin products in routine clinical practice for the treatment of type 2 diabetes in the UK. PATIENTS AND METHODS:Records were analyzed for patients with type 2 diabetes who had been initiated on biphasic insulin aspart 30 (BI...

journal_title：Advances in therapy

authors： Fakhoury WK,Richter H,Christensen TE

更新日期：2010-11-01 00:00:00

abstract：INTRODUCTION:Rhegmatogenous retinal detachment (RRD) with extensive choroidal detachment (CD), suprachoroidal fluid (SCF), and lower intraocular pressure (IOP) markedly increase the difficulty of pars plana vitrectomy (PPV) because it makes the insertion and placement of the trocar cannulas for PPV time-consuming and t...

journal_title：Advances in therapy

authors： Zhang Z,Fang D,Peng M,Wei Y,Wang L,Fan S,Zhang S

更新日期：2019-01-01 00:00:00

abstract：:This 6-month randomized study evaluated the safety and efficacy of sibutramine in 57 overweight Hispanic patients with hypertension. Following a 2-week washout to confirm the diagnosis of hypertension, antihypertensive medication was adjusted to achieve a blood pressure less than 140/90 mm Hg before institution of eit...

journal_title：Advances in therapy

authors： Fanghänel G,Cortinas L,Sánchez-Reyes L,Gómez-Santos R,Campos-Franco E,Berber A

更新日期：2003-03-01 00:00:00

abstract：:With the increasing availability of biosimilars, the practice of switching therapies for non-medical reasons between an originator biologic and an analogous biosimilar has become more common. The evidence to support this practice mostly comes from single-switch randomized controlled trials (RCTs) and real-world (RW) e...

journal_title：Advances in therapy

authors： Feagan BG,Marabani M,Wu JJ,Faccin F,Spronk C,Castañeda-Hernández G

更新日期：2020-11-01 00:00:00

abstract：:There has been increased interest in gout in both academic and clinical practice settings. Several reasons may explain this. The prevalence of both hyperuricemia and gout has risen in the last decades in developed countries and therefore the burden of gout has increased. The association of hyperuricemia and gout with ...

journal_title：Advances in therapy

authors： Perez-Ruiz F,Dalbeth N,Bardin T

更新日期：2015-01-01 00:00:00

abstract：INTRODUCTION:nab-Paclitaxel plus gemcitabine (nab-P + G) and FOLFIRINOX (FFX) are among the most common first-line (1L) therapies for metastatic adenocarcinoma of the pancreas (MPAC), but real-world data on their comparative effectiveness are limited. METHODS:This retrospective cohort study compared the efficacy and s...

journal_title：Advances in therapy

authors： Kim S,Signorovitch JE,Yang H,Patterson-Lomba O,Xiang CQ,Ung B,Parisi M,Marshall JL

更新日期：2018-10-01 00:00:00

abstract：:This study compared technetium-99m-hexakis-2-methoxyisobutyl-isonitrile (Tc-99m MIBI) with technetium-99m methylene iphosphonate (Tc-99m MDP) to determine whether Tc-99m MIBI could distinguish vertebral metastases from traumatic vertebral fractures. Twenty patients with traumatic vertebral fracture (and no malignant d...

journal_title：Advances in therapy

authors： Buyukdereli G,Ermin T,Kara O,Kibar M

更新日期：2006-01-01 00:00:00

abstract：:X-linked hypophosphataemia (XLH) is the most prevalent form of hereditary rickets characterized by an alteration of phosphate metabolism which frequently leads to the appearance of fractures, bone deformities and growth delay. Although the mechanism of growth impairment in patients with XLH still needs to be clarified...

journal_title：Advances in therapy

authors： Santos Rodríguez F

更新日期：2020-05-01 00:00:00