Comparative Effectiveness of nab-Paclitaxel Plus Gemcitabine vs FOLFIRINOX in Metastatic Pancreatic Cancer: A Retrospective Nationwide Chart Review in the United States.

abstract：INTRODUCTION:Aripiprazole and olanzapine are atypical antipsychotics. Both drugs can induce metabolic changes; however, the metabolic side effects produced by aripiprazole are more benign. The aim of the study was to evaluate if aripiprazole and olanzapine alter prolactin levels, lipid and glucose metabolism and hepati...

journal_title：Advances in therapy

authors： Koller D,Almenara S,Mejía G,Saiz-Rodríguez M,Zubiaur P,Román M,Ochoa D,Navares-Gómez M,Santos-Molina E,Pintos-Sánchez E,Abad-Santos F

更新日期：2020-12-05 00:00:00

abstract：:In the past 15 years, improvements in the treatment of HIV infection have dramatically reduced morbidity and mortality. Nucleoside reverse transcriptase inhibitors are the backbone of combination antiretroviral therapy for the treatment of HIV. One of the recommended and commonly used therapies in this class is the on...

journal_title：Advances in therapy

authors： Achenbach CJ,Scarsi KK,Murphy RL

更新日期：2010-01-01 00:00:00

abstract：:Propolis is a natural product produced by bees that was discovered through the study of traditional cures and knowledge of indigenous people throughout the world. It is rich in vitamins A, B, C, and E, and in amino acids, copper, iron, manganese, and zinc. The investigators studied the duration-dependent hepatoprotect...

journal_title：Advances in therapy

authors： Bhadauria M,Nirala SK,Shukla S

更新日期：2007-09-01 00:00:00

abstract：:This 6-month randomized study evaluated the safety and efficacy of sibutramine in 57 overweight Hispanic patients with hypertension. Following a 2-week washout to confirm the diagnosis of hypertension, antihypertensive medication was adjusted to achieve a blood pressure less than 140/90 mm Hg before institution of eit...

journal_title：Advances in therapy

authors： Fanghänel G,Cortinas L,Sánchez-Reyes L,Gómez-Santos R,Campos-Franco E,Berber A

更新日期：2003-03-01 00:00:00

abstract：INTRODUCTION:The present study aimed to identify preoperative factors that predispose the development of subretinal fluid (SRF) following successful macular hole (MH) surgery. METHODS:Thirty-four eyes of 33 consecutive patients that underwent pars plana vitrectomy for idiopathic full-thickness MH surgery were included...

journal_title：Advances in therapy

authors： Tranos PG,Stavrakas P,Vakalis AN,Asteriadis S,Lokovitis E,Konstas AG

更新日期：2015-07-01 00:00:00

abstract：INTRODUCTION:The objective of this study was to report outcome measures with third-generation pre-attached scrotal port adjustable transobturator male system (ATOMS) for male stress urinary incontinence (SUI) after radical prostatectomy. METHODS:A prospective open study was conducted on consecutive patients. Evaluatio...

journal_title：Advances in therapy

authors： Angulo JC,Arance I,Esquinas C,Dorado JF,Marcelino JP,Martins FE

更新日期：2017-05-01 00:00:00

abstract：:Nonketotic hyperosmolar coma (NHC) is characterized by severe hyperglycemia; absence of, or only slight ketosis; nonketotic acidosis; severe dehydration; depressed sensorium or frank coma; and various neurologic signs. This condition is uncommon in type 1 diabetes. Because of little or no osmotic diuresis in patients ...

journal_title：Advances in therapy

authors： Dogan E,Erkoc R,Sayarlioglu H,Buyukbese A

更新日期：2005-09-01 00:00:00

abstract：:In the last few years, immunotherapy has transformed the way we treat solid tumors, including melanoma, lung, head neck, breast, renal, and bladder cancers. Durable responses and long-term survival benefit has been experienced by many cancer patients, with favorable toxicity profiles of immunotherapeutic agents relati...

journal_title：Advances in therapy

authors： Arora S,Velichinskii R,Lesh RW,Ali U,Kubiak M,Bansal P,Borghaei H,Edelman MJ,Boumber Y

更新日期：2019-10-01 00:00:00

abstract：INTRODUCTION:Acute gastrointestinal bleeding (GIB) is a major cause of death in liver cirrhosis. This multicenter study aims to develop and validate a novel and easy-to-access model for predicting the prognosis of patients with cirrhosis and acute GIB. METHODS:Patients with cirrhosis and acute GIB were enrolled and ra...

journal_title：Advances in therapy

authors： Bai Z,Li B,Lin S,Liu B,Li Y,Zhu Q,Wu Y,Yang Y,Tang S,Meng F,Chen Y,Yuan S,Shao L,Qi X

更新日期：2019-11-01 00:00:00

abstract：INTRODUCTION:Adherence to diabetes medication has been linked to improved glycemic levels and lower costs, but previous research on adherence has typically involved oral antidiabetic medication or insulin. This study examines how adherence and persistence to once-daily liraglutide impact glycemic control and economic o...

journal_title：Advances in therapy

authors： Buysman EK,Liu F,Hammer M,Langer J

更新日期：2015-04-01 00:00:00

abstract：INTRODUCTION:Despite improved understanding of the risks of influenza and better vaccines for older patients, influenza vaccination rates remain subpar, including in high-risk groups such as older adults, and demonstrate significant racial and ethnic disparities. METHODS:This study considers demographic, clinical, and...

journal_title：Advances in therapy

authors： Hall LL,Xu L,Mahmud SM,Puckrein GA,Thommes EW,Chit A

更新日期：2020-05-01 00:00:00

abstract：INTRODUCTION:To determine patient and rheumatologist preferences for rheumatoid arthritis (RA) treatment attributes in Spain and to evaluate their attitude towards shared decision-making (SDM). METHODS:Observational, descriptive, exploratory and cross-sectional study based on a discrete choice experiment (DCE). To ide...

journal_title：Advances in therapy

authors： Díaz-Torné C,Urruticoechea-Arana A,Ivorra-Cortés J,Díaz S,Dilla T,Sacristán JA,Inciarte-Mundo J,Comellas M,Prades M,Lizán L

更新日期：2020-04-01 00:00:00

abstract：INTRODUCTION:ARTOS was an international, prospective, non-interventional, non-controlled observational study designed to determine the effectiveness, safety, and tolerability of moxifloxacin under daily-life conditions in patients with complicated skin and skin structure infections (cSSSIs) treated in Europe, the Middl...

journal_title：Advances in therapy

authors： Bogner JR,Kutaiman A,Esguerra-Alcalen M,Heldner S,Arvis P

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Mutation of human receptor tyrosine kinase epidermal growth factor receptor-2 (HER2) is a rare event, found in approximately 1% non-small cell lung cancers (NSCLC). The objective was to investigate the clinical characteristics and management of HER2-mutated NSCLCs in a real-life setting. METHODS:This multic...

journal_title：Advances in therapy

authors： Auliac JB,Dô P,Bayle S,Doubre H,Vinas F,Letreut J,Falchero L,Hauss PA,Thomas P,Chouaid C

更新日期：2019-08-01 00:00:00

abstract：:X-linked hypophosphataemia (XLH) is the most prevalent form of hereditary rickets characterized by an alteration of phosphate metabolism which frequently leads to the appearance of fractures, bone deformities and growth delay. Although the mechanism of growth impairment in patients with XLH still needs to be clarified...

journal_title：Advances in therapy

authors： Santos Rodríguez F

更新日期：2020-05-01 00:00:00

abstract：INTRODUCTION:Wet age-related macular degeneration (AMD) is a chronic eye condition that causes severe deterioration of vision and even blindness. Current wet AMD treatment in the UK involves the vascular endothelial growth factor inhibitors ranibizumab and aflibercept. Patients with wet AMD require frequent and long-te...

journal_title：Advances in therapy

authors： Ghosh W,Wickstead R,Claxton L,Kusel J,Taylor M,Fleetwood K,Pulikottil-Jacob R

更新日期：2016-09-01 00:00:00

abstract：INTRODUCTION:The traditional model of evaluating treatments based primarily on primary outcome measures has stumbled in its application to rare disease. Rare disease clinical trials face the methodological challenges of small, heterogeneous patient populations and relatively few validated, disease-specific outcome meas...

journal_title：Advances in therapy

authors： Contesse MG,Valentine JE,Wall TE,Leffler MG

更新日期：2019-05-01 00:00:00

abstract：INTRODUCTION:Randomized controlled trials and real-world data from the USA have shown similar glycemic control with insulin glargine 300 U/ml (Gla-300) and insulin glargine 100 U/ml (Gla-100) and reduced hypoglycemia risk with Gla-300. This real-world study describes the efficacy and safety of Gla-300 and Gla-100 in pa...

journal_title：Advances in therapy

authors： Escalada J,Bonnet F,Wu J,Bonnemaire M,Gupta S,Cambron-Mellott JM,Nicholls C,Müller-Wieland D

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Previous studies showed the relation of mental distress such as anxiety and depression to coronary vasoconstriction and myocardial ischemia. However, the mental health status of patients suspected to have vasospastic angina is unclear. METHODS:A total of 99 patients underwent intracoronary acetylcholine (AC...

journal_title：Advances in therapy

authors： Saito Y,Shoji T,Tateishi K,Kitahara H,Fujimoto Y,Kobayashi Y

更新日期：2020-09-01 00:00:00

abstract：:This double-blind, randomized, prospective study was conducted to compare the analgesic and sedative efficacy of fentanyl and meperidine in orthopedic closed reduction of fractures and dislocations undertaken in the emergency department. Seventy consecutive adult patients with fractures or dislocations suitable for re...

journal_title：Advances in therapy

authors： Soysal S,Karcioglu O,Demircan A,Topacoglu H,Serinken M,Ozucelik N,Tirpan K,Gunerli A

更新日期：2004-09-01 00:00:00

abstract：INTRODUCTION:Claims data (IBM MarketScan Commercial and MarketScan Medicare Supplemental databases) from June 30, 2011 to September 30, 2017 were used to evaluate the cost impact of human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer (MBC) in this retrospective cohort study. METHODS:The p...

journal_title：Advances in therapy

authors： Sussell JA,Sheinson D,Wu N,Shah-Manek B,Seetasith A

更新日期：2020-04-01 00:00:00

abstract：:The analgesic properties of 2 antiemetic agents--metoclopramide and ondansetron--were investigated in studies which showed that metoclopramide may decrease postoperative opioid requirements, but the analgesic effect of ondansetron is controversial. The postoperative effects of metoclopramide and ondansetron on pain in...

journal_title：Advances in therapy

authors： Derbent A,Uyar M,Demirag K,Uyer M,Kurtoglu E,Goktay A

更新日期：2005-07-01 00:00:00

abstract：:Shock is a serious acute circulatory failure leading to inadequate oxygen delivery to the cells. Its treatment is mainly based on circulating fluid optimization, and vasopressors to provide an adequate mean arterial pressure and microcirculatory flow. Norepinephrine is the drug of choice, but high dosages may be respo...

journal_title：Advances in therapy

authors： Puntillo F,Giglio M,Pasqualucci A,Brienza N,Paladini A,Varrassi G

更新日期：2020-09-01 00:00:00

abstract：INTRODUCTION:The 1100delC CHEK2 allele has been associated with a 1.4-to 4.7-fold increased risk of breast cancer in women carrying this mutation. Our study investigated the frequency of this allele in a Chinese population. METHODS:Using touchdown polymerase chain reaction, we sequenced the CHEK2.1100delC mutation in ...

journal_title：Advances in therapy

authors： Chen W,Yurong S,Liansheng N

更新日期：2008-05-01 00:00:00

abstract：INTRODUCTION:This study aimed to compare the challenge of puncture and catheterization and the effect of postoperative analgesia of ultrasound-guided continuous thoracic paravertebral block and the continuous epidural analgesia in patients receiving thoracoscopic surgery for lung cancer. METHODS:One-hundred and fifty ...

journal_title：Advances in therapy

authors： Huang QW,Li JB,Huang Y,Zhang WQ,Lu ZW

更新日期：2020-09-01 00:00:00

abstract：:Angio-immunoblastic T-cell lymphoma (AITL), a rare disease that constitutes 1% to 2% of non-Hodgkin's lymphomas, presents in middle-aged and elderly individuals. This report describes a patient with high-grade fever and lymphadenopathy. An extensive in-hospital work-up that included lymph node biopsy yielded negative ...

journal_title：Advances in therapy

authors： Usmani SZ,Sahay T,Eisenberg L

更新日期：2007-07-01 00:00:00

abstract：:Recently, immunotherapy has been shown to be an effective and helpful therapeutic option for the treatment of advanced non-small-cell lung cancer (NSCLC). The activity of antitumor T cells may be restored through the checkpoint blockade using anti-programmed death 1 or anti-programmed death ligand 1 (PD-L1) antibodies...

journal_title：Advances in therapy

authors： Incorvaia L,Fanale D,Badalamenti G,Barraco N,Bono M,Corsini LR,Galvano A,Gristina V,Listì A,Vieni S,Gori S,Bazan V,Russo A

更新日期：2019-10-01 00:00:00

abstract：INTRODUCTION:Anti-vascular endothelial growth factor therapy is the standard of care for neovascular age-related macular degeneration (nAMD). The dosage of two licensed agents, ranibizumab and aflibercept, was established through clinical trials; however, it is unclear if either agent is administered as recommended in ...

journal_title：Advances in therapy

authors： Skelly A,Carius HJ,Bezlyak V,Chen FK

更新日期：2017-12-01 00:00:00

abstract：INTRODUCTION:Benefit and risk of anticoagulation in cirrhotic patients with portal vein thrombosis (PVT) remain controversial, especially in those with asymptomatic PVT and in non-liver transplant candidates. Furthermore, the predictors of portal vein recanalization and bleeding events after anticoagulation are critica...

journal_title：Advances in therapy

authors： Wang L,Guo X,Xu X,De Stefano V,Plessier A,Noronha Ferreira C,Qi X

更新日期：2020-11-05 00:00:00

abstract：:This study was conducted to determine the reasons for the choice of self-prescribed laxatives and to acquire information on how they were used and tolerated. From November 1999 to February 2000, 70 pharmacies, uniformly located throughout the Campania region of southern Italy, distributed a questionnaire to purchasers...

journal_title：Advances in therapy

authors： Motola G,Mazzeo F,Rinaldi B,Capuano A,Rossi S,Russo F,Vitelli MR,Rossi F,Filippelli A

更新日期：2002-09-01 00:00:00