Ocular trauma in Turkey: a 2-year prospective study.

abstract：:The corneal toxicity of 2 intraocular pressure-lowering agents was compared in a rabbit cornea model with New Zealand White rabbits. Corneal epithelial morphology and cell size were assessed by in vivo confocal microscopy. Baseline microscopic examinations were performed on 1 eye of each animal. Two weeks later, the e...

journal_title：Advances in therapy

authors： Whitson JT,Cavanagh HD,Lakshman N,Petroll WM

更新日期：2006-09-01 00:00:00

abstract：INTRODUCTION:Data regarding the prevalence of immune thrombocytopenia (ITP) is limited, and is derived from North American population-based analyses. Therefore, the authors conducted the first study outside the United States (US) using the United Kingdom (UK) General Practice Research Database (GPRD) to estimate the ad...

journal_title：Advances in therapy

authors： Bennett D,Hodgson ME,Shukla A,Logie JW

更新日期：2011-12-01 00:00:00

abstract：:Atrial fibrillation (AF) and venous thromboembolism (VTE) are highly prevalent and relevant healthcare issues. Direct oral anticoagulants (DOACs) are now the first-choice for anticoagulant treatment of these conditions displaying a better efficacy/safety profile than vitamin-K antagonists, mainly due to significantly ...

journal_title：Advances in therapy

authors： Ballestri S,Capitelli M,Fontana MC,Arioli D,Romagnoli E,Graziosi C,Lonardo A,Marietta M,Dentali F,Cioni G

更新日期：2020-05-01 00:00:00

abstract：:Nonketotic hyperosmolar coma (NHC) is characterized by severe hyperglycemia; absence of, or only slight ketosis; nonketotic acidosis; severe dehydration; depressed sensorium or frank coma; and various neurologic signs. This condition is uncommon in type 1 diabetes. Because of little or no osmotic diuresis in patients ...

journal_title：Advances in therapy

authors： Dogan E,Erkoc R,Sayarlioglu H,Buyukbese A

更新日期：2005-09-01 00:00:00

abstract：:Clarithromycin, an advanced-generation macrolide antibiotic, has demonstrated excellent in vitro activity against group A beta-hemolytic streptococcus (GABHS). Potent activity against Streptococcus pyogenes and a favorable pharmacokinetic profile have made it a reasonable alternative for treatment of patients with str...

journal_title：Advances in therapy

authors： McCarty J,Hedrick JA,Gooch WM

更新日期：2000-01-01 00:00:00

abstract：:Eupatorium laevigatum Lam. is a plant common to the central region of Brazil, where it is a widely used remedy for lesions such as buccal aphthae. These painful inflammatory ulcers affect 50% of the general population. For the first part of this two-part study, a phytotherapeutic preparation from E. laevigatum extract...

journal_title：Advances in therapy

authors： Paulo Filho W,Ribeiro JE,Pinto DS

更新日期：2000-11-01 00:00:00

abstract：INTRODUCTION:Idiopathic pulmonary fibrosis (IPF) is the classic progressive fibrosing interstitial lung disease (ILD), but some patients with ILDs other than IPF also develop a progressive fibrosing phenotype (PF-ILD). Information on use and cost of healthcare resources in patients with PF-ILD is limited. METHODS:We u...

journal_title：Advances in therapy

authors： Olson AL,Maher TM,Acciai V,Mounir B,Quaresma M,Zouad-Lejour L,Wells CD,De Loureiro L

更新日期：2020-07-01 00:00:00

abstract：INTRODUCTION:The aim of the study was to investigate the role of the proteolytic fraction from Vasconcellea cundinamarcensis, designated as P1G10, on the healing of chronic foot ulcers in neuropathic patients with diabetes 2. METHODS:Fifty patients were enrolled in a prospective, randomized, double-blind trial, to ver...

journal_title：Advances in therapy

authors： Tonaco LAB,Gomes FL,Velasquez-Melendez G,Lopes MTP,Salas CE

更新日期：2018-04-01 00:00:00

abstract：INTRODUCTION:Advanced renal cell carcinoma (RCC) shows a propensity for extending into the tributaries of the renal veins, which poses a notable surgical challenge. In this study we addressed the question as to whether patients with RCC and vein involvement can be identified as having a significant risk of immediate de...

journal_title：Advances in therapy

authors： Akkoyun M,Merseburger AS,Kramer MW,Herrmann TR,Kuczyk MA,von Klot CA

更新日期：2015-08-01 00:00:00

abstract：INTRODUCTION:This trial was conducted to assess the long-term safety, efficacy, and benefit of early add-on of linagliptin to insulin in patients with type 2 diabetes mellitus (T2DM). METHODS:This trial enrolled 246 subjects. The subjects were randomized to the linagliptin group or the control group and were observed ...

journal_title：Advances in therapy

authors： Katsuno T,Shiraiwa T,Iwasaki S,Park H,Watanabe N,Kaneko S,Terasaki J,Hanafusa T,Imagawa A,Shimomura I,Ikegami H,Koyama H,Namba M,Miyagawa JI,TRUST2 study group.

更新日期：2021-01-28 00:00:00

abstract：:Many doubts surround the numerous forms of nonsurgical treatment of nonresectable hepatocellular carcinoma (HCC). Our study aimed to reach reliable conclusions on the actual efficacy of these treatments. We examined 85 studies involving a total of 6746 patients: 6113 were treated; the remaining 633 were not. We applie...

journal_title：Advances in therapy

authors： Malaguarnera M,Trovato G,Restuccia S,Giugno I,Franzé CM,Receputo G,Siciliano R,Motta M,Trovato BA

更新日期：1994-11-01 00:00:00

abstract：INTRODUCTION:An 8-week trial of amlodipine/valsartan/hydrochlorothiazide (Aml/Val/HCTZ) for moderate or severe hypertension demonstrated more-pronounced blood pressure (BP)-lowering effects compared with dual-component therapies. To elucidate the effects of time and baseline BP on the observed responses, exploratory an...

journal_title：Advances in therapy

authors： Calhoun DA,Crikelair NA,Yen J,Glazer RD

更新日期：2009-11-01 00:00:00

abstract：:In an open-label 12-week study, the safety and efficacy of bimatoprost 0.03% was evaluated in 55 patients with open-angle glaucoma or ocular hypertension inadequately controlled by topical beta-blocker monotherapy. Patients discontinued their topical beta-blocker therapy at the baseline visit and began bimatoprost mon...

journal_title：Advances in therapy

authors： Quinones R,Earl ML

更新日期：2004-11-01 00:00:00

abstract：:Treating hyperglycemia is a critical aspect of managing type 2 diabetes mellitus (T2DM), but can be especially challenging in patients from vulnerable groups such as those with chronic kidney disease, African Americans, and older people. The dipeptidyl peptidase (DPP)-4 inhibitors are relatively new oral antidiabetes ...

journal_title：Advances in therapy

authors： Kountz D

更新日期：2013-12-01 00:00:00

abstract：:Patients with acute myeloid leukemia (AML) with the t(8;21) karyotype generally have a favorable clinical course, but key prognostic factors remain poorly defined. This study was conducted to determine the prognoses and treatment outcomes of patients with AML with this unique cytogenetic change. A total of 22 patients...

journal_title：Advances in therapy

authors： Chen CC,Gau JP,Yu YB,Lu CH,Lee KD,You JY

更新日期：2007-07-01 00:00:00

abstract：:Chronic constipation (CC) and irritable bowel syndrome with constipation (IBS-C) are common gastrointestinal (GI) disorders. Current treatment options, either prescription or nonprescription medications, have limited efficacy in a subset of patients. There is significant demand for more efficacious medications for the...

journal_title：Advances in therapy

authors： Vazquez-Roque MI,Bouras EP

更新日期：2013-03-01 00:00:00

abstract：:The article "A Relative Cost of Control Analysis of Once-Weekly Semaglutide Versus Exenatide Extended-Release and Dulaglutide for Bringing Patients to HbA1c and Weight Loss Treatment Targets in the USA", written by Pierre Johansen, Barnaby Hunt, Neeraj N. Iyer, Tam Dang-Tan, Richard F. Pollock was originally published...

journal_title：Advances in therapy

authors： Johansen P,Hunt B,Iyer NN,Dang-Tan T,Pollock RF

更新日期：2019-05-01 00:00:00

abstract：INTRODUCTION:Oxycodone is one of the most commonly used opioid analgesics in the clinical management of pain. The present retrospective analysis aimed to determine the dose of oxycodone that could achieve effective control of moderate pain when combined with a fixed dose of acetaminophen, and the time required to reach...

journal_title：Advances in therapy

authors： Natoli S,Lazzari M,Carpenedo R,Palombo E,Silvi MB,Mammucari M,Dauri M

更新日期：2016-06-01 00:00:00

abstract：:Two patients with thalassemia minor and end-stage renal failure on hemodialysis were treated with epoetin zeta (Silapo, Retacrit; STADA, Germany), a medicinal product that was developed and registered as biosimilar to epoetin alfa. Dosing was titrated individually for two patients to achieve a stable hemoglobin (Hb) c...

journal_title：Advances in therapy

authors： Kumchev E,Koytchev R,Dimitrakov D,Stavrev P,Tsochev G,Siebert-Weigel M

更新日期：2008-12-01 00:00:00

abstract：INTRODUCTION:Extraintestinal manifestations (EIMs) in patients with Crohn's disease (CD) are common and associated with additional morbidity. This study aimed to evaluate the effect of adalimumab therapy on EIM resolution and identify potential predictors of EIM resolution in adult and pediatric patients with moderate ...

journal_title：Advances in therapy

authors： Louis EJ,Reinisch W,Schwartz DA,Löfberg R,Robinson AM,Berg S,Wang AW,Maa JF,Huang B,Pappalardo B

更新日期：2018-04-01 00:00:00

abstract：:Traveling through several time zones results in a constellation of symptoms known as jet lag. These include reduced alertness, daytime fatigue, loss of appetite, reduced cognitive skills, and disruption of the sleep/wake cycle. In susceptible air travel passengers, jet lag may exacerbate affective illness and result i...

journal_title：Advances in therapy

authors： Srinivasan V,Singh J,Pandi-Perumal SR,Brown GM,Spence DW,Cardinali DP

更新日期：2010-11-01 00:00:00

abstract：:Knee osteoarthritis (KOA) is the most common musculoskeletal disorder, especially in middle up to old age. KOA also results in many complications like changes in gait. Nowadays, changes in lifestyle and the reduced physical activity make people more vulnerable to KOA. Therefore, considering the increasing prevalence o...

journal_title：Advances in therapy

authors： Ganjeh S,Rezaeian ZS,Mostamand J

更新日期：2020-08-01 00:00:00

abstract：INTRODUCTION:ARTOS was an international, prospective, non-interventional, non-controlled observational study designed to determine the effectiveness, safety, and tolerability of moxifloxacin under daily-life conditions in patients with complicated skin and skin structure infections (cSSSIs) treated in Europe, the Middl...

journal_title：Advances in therapy

authors： Bogner JR,Kutaiman A,Esguerra-Alcalen M,Heldner S,Arvis P

更新日期：2013-06-01 00:00:00

abstract：:Propolis is a natural product produced by bees that was discovered through the study of traditional cures and knowledge of indigenous people throughout the world. It is rich in vitamins A, B, C, and E, and in amino acids, copper, iron, manganese, and zinc. The investigators studied the duration-dependent hepatoprotect...

journal_title：Advances in therapy

authors： Bhadauria M,Nirala SK,Shukla S

更新日期：2007-09-01 00:00:00

abstract：INTRODUCTION:This study aims to evaluate the early predictive value for postoperative sepsis and 30-day mortality in liver transplant patients using sequential organ failure assessment (SOFA). METHODS:A total of 96 liver transplant patients were enrolled into this study from February 2015 to June 2018. The general inf...

journal_title：Advances in therapy

authors： Wang XW,Niu XG,Li JX,Zhang SS,Jiao XF

更新日期：2019-03-01 00:00:00

abstract：INTRODUCTION:Secukinumab, a fully human monoclonal antibody that directly inhibits interleukin-17A, has demonstrated robust efficacy in the treatment of moderate to severe psoriasis (PsO), psoriatic arthritis (PsA) and ankylosing spondylitis (AS), with a rapid onset of action, sustained long-term clinical responses and...

journal_title：Advances in therapy

authors： Kiltz U,Sfikakis PP,Gaffney K,Sator PG,von Kiedrowski R,Bounas A,Gullick N,Conrad C,Rigopoulos D,Lespessailles E,Romanelli M,Ghislain PD,Brandt-Jürgens J,Rashkov R,Aassi M,Orsenigo R,Perella C,Pournara E,Gathmann S,

更新日期：2020-06-01 00:00:00

abstract：INTRODUCTION:Wet age-related macular degeneration (AMD) is a chronic eye condition that causes severe deterioration of vision and even blindness. Current wet AMD treatment in the UK involves the vascular endothelial growth factor inhibitors ranibizumab and aflibercept. Patients with wet AMD require frequent and long-te...

journal_title：Advances in therapy

authors： Ghosh W,Wickstead R,Claxton L,Kusel J,Taylor M,Fleetwood K,Pulikottil-Jacob R

更新日期：2016-09-01 00:00:00

abstract：INTRODUCTION:The aim of this study was to investigate whether the efficacy of liraglutide observed in randomized controlled trials translates into therapeutic benefits in the French population during routine clinical practice. METHODS:This observational, prospective, multicenter study included 3152 adults with type 2 ...

journal_title：Advances in therapy

authors： Gautier JF,Martinez L,Penfornis A,Eschwège E,Charpentier G,Huret B,Madani S,Gourdy P

更新日期：2015-09-01 00:00:00

abstract：:Fibroids, the most common tumor in women of reproductive age, impact negatively on women's health and quality of life, and have significant cost implications for their management. The current mainstay treatments are surgical (myomectomy and hysterectomy) and more recently radiological (UAE and focused ultrasound surge...

journal_title：Advances in therapy

authors： Talaulikar VS,Manyonda IT

更新日期：2012-08-01 00:00:00

abstract：INTRODUCTION:Crohn's disease (CD) is a chronic inflammatory disease of the gastrointestinal tract. This real-world study evaluated persistence, dose titration, health care resource utilization (HCRU) and associated costs, and medication use among CD patients treated with ustekinumab (UST) in several pooled US commercia...

journal_title：Advances in therapy

authors： Obando C,Ding Z,Muser E,Vaidya N,Qiang W,Sun X,Wang H,Mallampati R,Xie L

更新日期：2020-05-01 00:00:00