Effect of Ivabradine on Endothelial Function in Patients with Stable Angina Pectoris: Assessment with the Endo-PAT 2000 Device.

abstract：:Life expectancy has increased substantially over the last few decades, leading to a worldwide increase in the prevalence and burden of aging-associated diseases. Recent evidence has proven that cellular senescence contributes substantially to the development of these disorders. Cellular senescence is a state of cell c...

journal_title：Advances in therapy

authors： Amaya-Montoya M,Pérez-Londoño A,Guatibonza-García V,Vargas-Villanueva A,Mendivil CO

更新日期：2020-04-01 00:00:00

abstract：INTRODUCTION:Advanced renal cell carcinoma (RCC) shows a propensity for extending into the tributaries of the renal veins, which poses a notable surgical challenge. In this study we addressed the question as to whether patients with RCC and vein involvement can be identified as having a significant risk of immediate de...

journal_title：Advances in therapy

authors： Akkoyun M,Merseburger AS,Kramer MW,Herrmann TR,Kuczyk MA,von Klot CA

更新日期：2015-08-01 00:00:00

abstract：INTRODUCTION:Rhegmatogenous retinal detachment (RRD) with extensive choroidal detachment (CD), suprachoroidal fluid (SCF), and lower intraocular pressure (IOP) markedly increase the difficulty of pars plana vitrectomy (PPV) because it makes the insertion and placement of the trocar cannulas for PPV time-consuming and t...

journal_title：Advances in therapy

authors： Zhang Z,Fang D,Peng M,Wei Y,Wang L,Fan S,Zhang S

更新日期：2019-01-01 00:00:00

abstract：INTRODUCTION:Infantile hemangiomas (IH) are the most common benign vascular tumors of childhood, with an incidence of 5-10% during the first year of age. Propranolol is considered the first-line treatment for this condition. Potentially there is a high probability of negative results to therapy, because in many countri...

journal_title：Advances in therapy

authors： Castaneda S,Melendez-Lopez S,Garcia E,De la Cruz H,Sanchez-Palacio J

更新日期：2016-10-01 00:00:00

abstract：:Nateglinide is an oral antidiabetic medication that acts through rapid, short-term stimulation of insulin production. This study was undertaken to identify the incidence and nature of adverse effects of nateglinide and to assess its efficacy in clinical practice. Patients (n = 3254) were recruited from 606 centers in ...

journal_title：Advances in therapy

authors： Taki H,Maki T,Iso T,Iwamoto K,Kajiura T

更新日期：2005-09-01 00:00:00

abstract：INTRODUCTION:To evaluate, from the patient's perspective, the burden of pain associated with hip/knee osteoarthritis (OA) in the USA and selected European Union (EU) countries. METHODS:Data were drawn from the 2017 global Adelphi OA Disease Specific Programme™ (DSP). Patients with hip/knee OA were stratified based on ...

journal_title：Advances in therapy

authors： Jackson J,Iyer R,Mellor J,Wei W

更新日期：2020-09-01 00:00:00

abstract：INTRODUCTION:Evidence suggests that elevated plasma levels of B-type natriuretic peptide (BNP) are found in patients with chronic obstructive pulmonary disease (COPD) and right ventricular dysfunction. We examined the effects of exercise on plasma BNP levels in patients with COPD who have normal right ventricular funct...

journal_title：Advances in therapy

authors： Gemici G,Erdim R,Celiker A,Tokay S,Ones T,Inanir S,Oktay A

更新日期：2008-07-01 00:00:00

abstract：PURPOSE:To evaluate the impact on cost, time, resource use, and clinic workflow of converting the route of drug administration from a neurokinin-1 receptor antagonist (NK-1 RA) 30-min intravenous (IV) infusion to aprepitant IV, and more specifically to IV push, within a multicenter community oncology practice. METHODS...

journal_title：Advances in therapy

authors： Burns D,Kula J,Marshall S,Ashworth E,Ornelas M

更新日期：2020-07-01 00:00:00

abstract：INTRODUCTION:In FRESCO (Fruquintinib Efficacy and Safety in 3+ Line Colorectal Cancer Patients) trial, fruquintinib demonstrated a statistically significant and clinically meaningful overall survival benefit in Chinese patients with metastatic colorectal cancer (mCRC). However, its safety profile, including adverse eve...

journal_title：Advances in therapy

authors： Li J,Guo W,Bai Y,Deng Y,Yang L,Chen Z,Zhong H,Xu R,Pan H,Shu Y,Yuan Y,Zhou J,Xu N,Liu T,Ma D,Wu C,Cheng Y,Xu J,Chen D,Li W,Sun S,Yu Z,Cao P,Shen L,Chen H,Wang S,Wang H,Fan S,Guo X,Wang N,Han R

更新日期：2020-11-01 00:00:00

abstract：:Designed to provide information about patients with schizophrenia who switch from depot neuroleptics to the oral, atypical antipsychotic risperidone, this multicenter observational study enrolled patients who wished to stop the depot, had an unsatisfactory response, or experienced unacceptable side effects. Individual...

journal_title：Advances in therapy

authors： Desai NM,Huq Z,Martin SD,McDonald G

更新日期：1999-03-01 00:00:00

abstract：:Endophthalmitis is an intraocular inflammatory condition which may or may not be caused by infective agents. Noninfectious (sterile) endophthalmitis may be attributable to various causes including postoperative retained soft lens matter or toxicity following introduction of other agents into the eye. Infectious endoph...

journal_title：Advances in therapy

authors： Tranos P,Dervenis N,Vakalis AN,Asteriadis S,Stavrakas P,Konstas AG

更新日期：2016-05-01 00:00:00

abstract：:Propolis is a natural product produced by bees that was discovered through the study of traditional cures and knowledge of indigenous people throughout the world. It is rich in vitamins A, B, C, and E, and in amino acids, copper, iron, manganese, and zinc. The investigators studied the duration-dependent hepatoprotect...

journal_title：Advances in therapy

authors： Bhadauria M,Nirala SK,Shukla S

更新日期：2007-09-01 00:00:00

abstract：INTRODUCTION:This study aimed to compare the challenge of puncture and catheterization and the effect of postoperative analgesia of ultrasound-guided continuous thoracic paravertebral block and the continuous epidural analgesia in patients receiving thoracoscopic surgery for lung cancer. METHODS:One-hundred and fifty ...

journal_title：Advances in therapy

authors： Huang QW,Li JB,Huang Y,Zhang WQ,Lu ZW

更新日期：2020-09-01 00:00:00

abstract：:Resistance to first- and second-generation anaplastic lymphoma kinase (ALK) tyrosine kinase inhibitors (TKIs) and development and progression of central nervous system metastases remain significant issues in the treatment of ALK-positive non-small-cell lung cancer. Lorlatinib is a novel third-generation ALK TKI that i...

journal_title：Advances in therapy

authors： Reed M,Rosales AS,Chioda MD,Parker L,Devgan G,Kettle J

更新日期：2020-06-01 00:00:00

abstract：INTRODUCTION:Janus kinase (JAK) inhibitors are a class of targeted therapies for rheumatoid arthritis (RA) with established clinical efficacy. However, little is known about their efficacy compared with each other. This network meta-analysis (NMA) estimated the comparative efficacy of JAK inhibitors currently approved ...

journal_title：Advances in therapy

authors： Pope J,Sawant R,Tundia N,Du EX,Qi CZ,Song Y,Tang P,Betts KA

更新日期：2020-05-01 00:00:00

abstract：:Permixon, the lipidosterolic extract of Serenoa repens, is widely used for the treatment of symptoms associated with benign prostatic hyperplasia (BPH). This open study assessed the efficacy and tolerability of Permixon 160 mg twice daily administered for 2 years. One hundred fifty-five men with clinically diagnosed B...

journal_title：Advances in therapy

authors： Pytel YA,Vinarov A,Lopatkin N,Sivkov A,Gorilovsky L,Raynaud JP

更新日期：2002-11-01 00:00:00

abstract：:Endocrine therapy (ET) is integral to the treatment of hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) metastatic breast cancer (MBC). Aromatase inhibitors (AIs; e.g., anastrozole, letrozole, exemestane), selective estrogen receptor modulators (e.g., tamoxifen), and the selec...

journal_title：Advances in therapy

authors： Nagaraj G,Ma CX

更新日期：2020-11-15 00:00:00

abstract：:This study was conducted to assess clinical and cost outcomes associated with the use of daptomycin. This objective was addressed through a consecutive patient chart review of the first 50 inpatients treated with daptomycin. Type of infection, identity of isolated pathogens, prior therapy, duration of therapy, length ...

journal_title：Advances in therapy

authors： Fossaceca C

更新日期：2007-05-01 00:00:00

abstract：INTRODUCTION:Fixed-combination intraocular pressure (IOP)-lowering medications simplify treatment regimens for patients requiring 2 ocular hypotensive agents to maintain sufficiently low IOP. The aim of this study was to evaluate the safety and efficacy of fixed-combination brinzolamide 1%/brimonidine 0.2% (BBFC) versu...

journal_title：Advances in therapy

authors： Gandolfi SA,Lim J,Sanseau AC,Parra Restrepo JC,Hamacher T

更新日期：2014-12-01 00:00:00

abstract：INTRODUCTION:To evaluate the retinal function and the relative neural conduction along the visual pathway after treatment with citicoline in liposomal formulation (CLF) eye drops in patients with open angle glaucoma (OAG). METHODS:Twelve OAG patients (mean age ± standard deviation 52.58 ± 11.39 years, intraocular pres...

journal_title：Advances in therapy

authors： Parisi V,Oddone F,Roberti G,Tanga L,Carnevale C,Ziccardi L,Manni G

更新日期：2019-04-01 00:00:00

abstract：INTRODUCTION:Vitamin E is one of the most promising agents for nonalcoholic steatohepatitis (NASH) treatment, and its drug responsiveness may be closely associated with haptoglobin (Hp) genotype. However, its efficacy and safety remain unknown in China. This clinical trial of vitamin E versus placebo for the treatment ...

journal_title：Advances in therapy

authors： Zang S,Chen J,Song Y,Bai L,Chen J,Chi X,He F,Sheng H,Wang J,Xie S,Xie W,Yang Y,Zhang J,Zheng M,Zou Z,Wang B,Shi J,Chinese NAFLD Clinical Research Network (CNAFLD CRN).

更新日期：2018-02-01 00:00:00

abstract：:Knee osteoarthritis (KOA) is the most common musculoskeletal disorder, especially in middle up to old age. KOA also results in many complications like changes in gait. Nowadays, changes in lifestyle and the reduced physical activity make people more vulnerable to KOA. Therefore, considering the increasing prevalence o...

journal_title：Advances in therapy

authors： Ganjeh S,Rezaeian ZS,Mostamand J

更新日期：2020-08-01 00:00:00

abstract：:Recently, high levels of neurotrophic factors have been found in bronchial asthma; these factors include nerve growth factor, brain-derived neurotrophic factor, and leukemia inhibitory factor, among others. Neurotrophic factors are first synthesized in bronchial epithelial cells, immune cells, and other cells in the a...

journal_title：Advances in therapy

authors： Feng JT,Hu CP,Li XZ

更新日期：2007-05-01 00:00:00

abstract：INTRODUCTION:Secukinumab, a fully human monoclonal antibody that directly inhibits interleukin-17A, has demonstrated robust efficacy in the treatment of moderate to severe psoriasis (PsO), psoriatic arthritis (PsA) and ankylosing spondylitis (AS), with a rapid onset of action, sustained long-term clinical responses and...

journal_title：Advances in therapy

authors： Kiltz U,Sfikakis PP,Gaffney K,Sator PG,von Kiedrowski R,Bounas A,Gullick N,Conrad C,Rigopoulos D,Lespessailles E,Romanelli M,Ghislain PD,Brandt-Jürgens J,Rashkov R,Aassi M,Orsenigo R,Perella C,Pournara E,Gathmann S,

更新日期：2020-06-01 00:00:00

abstract：:Recently, immunotherapy has been shown to be an effective and helpful therapeutic option for the treatment of advanced non-small-cell lung cancer (NSCLC). The activity of antitumor T cells may be restored through the checkpoint blockade using anti-programmed death 1 or anti-programmed death ligand 1 (PD-L1) antibodies...

journal_title：Advances in therapy

authors： Incorvaia L,Fanale D,Badalamenti G,Barraco N,Bono M,Corsini LR,Galvano A,Gristina V,Listì A,Vieni S,Gori S,Bazan V,Russo A

更新日期：2019-10-01 00:00:00

abstract：:Venous leg ulcers (VLUs) are the most severe manifestation of chronic venous disease (CVD). Due to their chronic nature, high recurrence rate and slow healing time, VLUs account for 80% of all leg ulcers seen in patients with CVD. VLUs impose a heavy burden on patients that reduces their quality of life; VLUs also rep...

journal_title：Advances in therapy

authors： Nicolaides AN

更新日期：2020-02-01 00:00:00

abstract：INTRODUCTION:The findings of many new cardiology clinical trials over the last year have been published or presented at major international meetings. This paper aims to describe and place in context a summary of the key clinical trials in cardiology presented between January and December 2016. METHODS:The authors revi...

journal_title：Advances in therapy

authors： Gray A,McQuillan C,Menown IBA

更新日期：2017-07-01 00:00:00

abstract：PURPOSE:To compare the efficacy of bromfenac 0.09% and dexamethasone 0.1% in the treatment of anterior chamber inflammation after uncomplicated cataract surgery. METHODS:Seventy-six patients with senile cataracts and no other ocular comorbidities who underwent uneventful phacoemulsification were randomized 1:1 to rece...

journal_title：Advances in therapy

authors： Coassin M,De Maria M,Mastrofilippo V,Braglia L,Cimino L,Sartori A,Fontana L

更新日期：2019-10-01 00:00:00

abstract：INTRODUCTION:Data regarding the prevalence of immune thrombocytopenia (ITP) is limited, and is derived from North American population-based analyses. Therefore, the authors conducted the first study outside the United States (US) using the United Kingdom (UK) General Practice Research Database (GPRD) to estimate the ad...

journal_title：Advances in therapy

authors： Bennett D,Hodgson ME,Shukla A,Logie JW

更新日期：2011-12-01 00:00:00

abstract：INTRODUCTION:Aripiprazole and olanzapine are atypical antipsychotics. Both drugs can induce metabolic changes; however, the metabolic side effects produced by aripiprazole are more benign. The aim of the study was to evaluate if aripiprazole and olanzapine alter prolactin levels, lipid and glucose metabolism and hepati...

journal_title：Advances in therapy

authors： Koller D,Almenara S,Mejía G,Saiz-Rodríguez M,Zubiaur P,Román M,Ochoa D,Navares-Gómez M,Santos-Molina E,Pintos-Sánchez E,Abad-Santos F

更新日期：2020-12-05 00:00:00