Breaking Barriers to Effective Type 2 Diabetes Management: Findings from the use of the OPTIMA© Questionnaire in Clinical Practice.

abstract：INTRODUCTION:This pooled analysis of data from three phase 3 studies in patients with chronic osteoarthritis knee or low back pain evaluated the efficacy and tolerability of tapentadol prolonged release (PR; 100-250 mg twice daily) compared with placebo and oxycodone hydrochloride (HCl) controlled release (CR; 20-50 mg...

journal_title：Advances in therapy

authors： Lange B,Kuperwasser B,Okamoto A,Steup A,Häufel T,Ashworth J,Etropolski M

更新日期：2010-06-01 00:00:00

abstract：INTRODUCTION:High-dose intravenous esomeprazole is the only approved pharmacological treatment for the prevention of peptic ulcer rebleeding (currently approved in over 100 countries worldwide), but has not yet been approved in China. This study aimed to evaluate a high-dose esomeprazole intravenous regimen vs. an acti...

journal_title：Advances in therapy

authors： Bai Y,Chen DF,Wang RQ,Chen YX,Shi RH,Tian DA,Chen H,Eklund S,Li ZS,Chinese Peptic Ulcer Bleeding Research Group.

更新日期：2015-11-01 00:00:00

abstract：INTRODUCTION:Idiopathic pulmonary fibrosis (IPF) is the classic progressive fibrosing interstitial lung disease (ILD), but some patients with ILDs other than IPF also develop a progressive fibrosing phenotype (PF-ILD). Information on use and cost of healthcare resources in patients with PF-ILD is limited. METHODS:We u...

journal_title：Advances in therapy

authors： Olson AL,Maher TM,Acciai V,Mounir B,Quaresma M,Zouad-Lejour L,Wells CD,De Loureiro L

更新日期：2020-07-01 00:00:00

abstract：:This 4-week double-blind, placebo-controlled study assessed the efficacy of impulse magnetic-field therapy for insomnia. One hundred one patients were randomly assigned to either active treatment (n = 50) or placebo (n = 51) and allocated to one of three diagnostic groups: (1) sleep latency; (2) interrupted sleep; or ...

journal_title：Advances in therapy

authors： Pelka RB,Jaenicke C,Gruenwald J

更新日期：2001-07-01 00:00:00

abstract：:Convergent evidence indicates that abnormalities in the innate immune system may be pertinent to the pathogenesis, phenomenology, and possible treatment of several mental disorders. In keeping with this view, the targeting of interleukin-6 with the human monoclonal antibody sirukumab may represent a possible treatment...

journal_title：Advances in therapy

authors： Zhou AJ,Lee Y,Salvadore G,Hsu B,Fonseka TM,Kennedy SH,McIntyre RS

更新日期：2017-01-01 00:00:00

abstract：:In this double-blind, randomized, placebo-controlled, prospective study, the clinical efficacy and tolerability of oral Hypericum extract STW 3-VI (Laif) 900 mg once daily was compared with that of placebo. A total of 140 outpatients (94 women; 46 men) with moderate depressive disorders and a 17-item Hamilton Depressi...

journal_title：Advances in therapy

authors： Uebelhack R,Gruenwald J,Graubaum HJ,Busch R

更新日期：2004-07-01 00:00:00

abstract：INTRODUCTION:The aim of this analysis was to characterize the safety and tolerability of empagliflozin in patients with type 2 diabetes mellitus (T2DM) who were randomized to empagliflozin (10/25 mg) or placebo in clinical trials. METHODS:Pooled data from 20 trials were analyzed for patients with T2DM treated with emp...

journal_title：Advances in therapy

authors： Kinduryte Schorling O,Clark D,Zwiener I,Kaspers S,Lee J,Iliev H

更新日期：2020-08-01 00:00:00

abstract：:Duodenal self-expandable metal stents (SEMS) are designed for palliation and prompt relief of malignant gastric outlet obstruction (GOO). This mini-invasive endoscopic treatment is preferable to surgery due to its lower morbidity and mortality, shorter hospitalization, and earlier symptoms relief; furthermore endoscop...

journal_title：Advances in therapy

authors： Boškoski I,Tringali A,Familiari P,Mutignani M,Costamagna G

更新日期：2010-10-01 00:00:00

abstract：:Tumor necrosis factor (TNF) inhibitors are widely used biologics for the treatment of several chronic inflammatory diseases. The launch of anti-TNF biosimilars has introduced the possibility of non-medical switching between originator biologics and their biosimilars. However, the potential clinical and patient-reporte...

journal_title：Advances in therapy

authors： Numan S,Faccin F

更新日期：2018-09-01 00:00:00

abstract：INTRODUCTION:The long-term safety of dimethyl fumarate (DMF) in patients with relapsing-remitting multiple sclerosis (RRMS) has been studied in mainly Caucasian patients. The present interim analysis aimed to evaluate the 72-week safety of DMF in Japanese patients with RRMS. METHODS:Safety data of Japanese subjects en...

journal_title：Advances in therapy

authors： Ochi H,Niino M,Onizuka Y,Hiramatsu K,Hase M,Yun J,Matta A,Torii S

更新日期：2018-10-01 00:00:00

abstract：INTRODUCTION:Hypertension and hypercholesterolaemia are important contributors to the development and progression of atherosclerosis. The coexistence of these two conditions is rather common: hypercholesterolaemia is present in 40-60% of hypertensive patients. Remarkably, patient compliance with antihypertensive regime...

journal_title：Advances in therapy

authors： Simon A,Dézsi CA

更新日期：2019-08-01 00:00:00

abstract：INTRODUCTION:This study characterized the multidose pharmacokinetic (PK) characteristics of posaconazole tablets used as prophylactic antifungal therapy in Chinese patients with acute myelogenous leukemia (AML) at risk for invasive fungal infection (IFI). METHODS:Participants in this open-label, single-arm, phase 1b s...

journal_title：Advances in therapy

authors： Liu K,Wu D,Li J,Chen H,Ning H,Zhao T,Dai H,Chen L,Mangin E,Winchell GA,Waskin H,Jiang J,Qiu Y,Zhao XM

更新日期：2020-05-01 00:00:00

abstract：INTRODUCTION:Vitamin E is one of the most promising agents for nonalcoholic steatohepatitis (NASH) treatment, and its drug responsiveness may be closely associated with haptoglobin (Hp) genotype. However, its efficacy and safety remain unknown in China. This clinical trial of vitamin E versus placebo for the treatment ...

journal_title：Advances in therapy

authors： Zang S,Chen J,Song Y,Bai L,Chen J,Chi X,He F,Sheng H,Wang J,Xie S,Xie W,Yang Y,Zhang J,Zheng M,Zou Z,Wang B,Shi J,Chinese NAFLD Clinical Research Network (CNAFLD CRN).

更新日期：2018-02-01 00:00:00

abstract：INTRODUCTION:The aim of this study was to evaluate the effectiveness of re-education in the insulin injection technique for glycemic control. METHODS:A preliminary experimental study was performed with 87 insulin-treated diabetic outpatients (11 with type 1 diabetes, 76 with type 2 diabetes; 43 men, 44 women). All pat...

journal_title：Advances in therapy

authors： Nakatani Y,Matsumura M,Monden T,Aso Y,Nakamoto T

更新日期：2013-10-01 00:00:00

abstract：:A 54-y-old patient with rheumatoid arthritis (RA) and bilateral lower-limb lymphoedema is presented. Complete decongestive physical therapy (CDP) is the cornerstone of the management programme in all patients suffering from lymphoedema associated with RA, but it is not clear which therapy is the most effective in decr...

journal_title：Advances in therapy

authors： Eyigor S,Karapolat H,Kirazli Y

更新日期：2008-01-01 00:00:00

abstract：:The aims of this study were to determine whether the nursing costs of functional disability could be assessed retrospectively and, if so, whether this method was sensitive enough to show the influence of a treatment on economic costs. Four studies were available for this purpose: three randomized, double-blind, place...

journal_title：Advances in therapy

authors： Vlietinck R,Van Loon H,Van de Broele H,Tormans G

更新日期：1993-09-01 00:00:00

abstract：:The extensive use of angiotensin-converting enzyme inhibitors (ACEIs) as antihypertensive agents and the huge amount of data collected in clinical trials and post-marketing studies has allowed the extending of the indication of ACEIs beyond blood pressure control. Current guidelines recommend ACEIs in symptomatic pati...

journal_title：Advances in therapy

authors： Borghi C,Omboni S

更新日期：2020-10-01 00:00:00

abstract：INTRODUCTION:Pulmonary arterial hypertension (PAH) is associated with poor prognosis despite significant recent advances in its treatment. An intravenous formulation of epoprostenol sodium containing glycine and mannitol (epoprostenol GM; GlaxoSmithKline, London, UK) is widely used to treat PAH. A new formulation of ep...

journal_title：Advances in therapy

authors： Tamura Y,Ono T,Fukuda K,Satoh T,Sasayama S

更新日期：2013-05-01 00:00:00

abstract：INTRODUCTION:The present study aimed to identify preoperative factors that predispose the development of subretinal fluid (SRF) following successful macular hole (MH) surgery. METHODS:Thirty-four eyes of 33 consecutive patients that underwent pars plana vitrectomy for idiopathic full-thickness MH surgery were included...

journal_title：Advances in therapy

authors： Tranos PG,Stavrakas P,Vakalis AN,Asteriadis S,Lokovitis E,Konstas AG

更新日期：2015-07-01 00:00:00

abstract：:Multiple, potentially practice-changing cardiology trials have been presented or published over the past year. In this paper, we summarize and place in clinical context, new data regarding management of acute coronary syndrome and ST-elevation myocardial infarction (copeptin assessment, otamixaban, cangrelor, prasugre...

journal_title：Advances in therapy

authors： McNeice AH,McAleavey NM,Menown IB

更新日期：2014-08-01 00:00:00

abstract：:Patients with reversible bronchospasm benefit from the use of inhaled beta-adrenergic agents. In this retrospective study of 24 older patients with a variety of conditions associated with reversible bronchospasm--asthma, asthma with emphysema, chronic bronchitis, and asthmatic bronchitis--symptomatic improvement was n...

journal_title：Advances in therapy

authors： Messina MS

更新日期：1995-05-01 00:00:00

abstract：INTRODUCTION:Prostate cancer (PC) is the second leading cause of cancer death among US men and accounts for considerable healthcare expenditures. We evaluated economic outcomes in men with chemotherapy-naïve metastatic castration-resistant PC (mCRPC) treated with enzalutamide or abiraterone acetate plus prednisone (abi...

journal_title：Advances in therapy

authors： Ramaswamy K,Lechpammer S,Mardekian J,Huang A,Schultz NM,Sandin R,Wang L,Baser O,George DJ

更新日期：2020-05-01 00:00:00

abstract：:Some patients with interstitial lung diseases (ILDs) other than idiopathic pulmonary fibrosis exhibit a progressive clinical phenotype. These chronic progressive fibrosing ILDs have a variety of underlying diseases, and their prevalence is currently unknown. Here we carry out the first systematic review of literature ...

journal_title：Advances in therapy

authors： Olson A,Hartmann N,Patnaik P,Wallace L,Schlenker-Herceg R,Nasser M,Richeldi L,Hoffmann-Vold AM,Cottin V

更新日期：2020-12-14 00:00:00

abstract：INTRODUCTION:Secukinumab, a fully human monoclonal antibody that directly inhibits interleukin-17A, has demonstrated robust efficacy in the treatment of moderate to severe psoriasis (PsO), psoriatic arthritis (PsA) and ankylosing spondylitis (AS), with a rapid onset of action, sustained long-term clinical responses and...

journal_title：Advances in therapy

authors： Kiltz U,Sfikakis PP,Gaffney K,Sator PG,von Kiedrowski R,Bounas A,Gullick N,Conrad C,Rigopoulos D,Lespessailles E,Romanelli M,Ghislain PD,Brandt-Jürgens J,Rashkov R,Aassi M,Orsenigo R,Perella C,Pournara E,Gathmann S,

更新日期：2020-06-01 00:00:00

abstract：INTRODUCTION:This retrospective study evaluates the efficacy of palliative chemotherapy with a modified docetaxel, cisplatin, 5-fluorouracil (5-FU; "TPF" regimen) regimen (mTPF; reduced doses of docetaxel, cisplatin, and 5-FU with reduction of intravenous 5-FU from 4 days to 2 days) in Asian patients with recurrent and...

journal_title：Advances in therapy

authors： Lin JT,Lai GM,Chang TH,Liu MT,Bi CP,Wang JW,Chen MK

更新日期：2012-01-01 00:00:00

abstract：:Bacterial translocation is the passage of bacteria or endotoxins from the gastrointestinal tract to extraintestinal sites, such as mesenteric lymph nodes, liver, spleen, and bloodstream. In this study, the investigators examined the effects of various enteral nutrients on bacterial translocation and intestinal morphol...

journal_title：Advances in therapy

authors： Aydogan A,Kismet K,Kilicoglu B,Erel S,Ozcan AH,Gollu A,Yildiz E,Akkus MA

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:Despite improved understanding of the risks of influenza and better vaccines for older patients, influenza vaccination rates remain subpar, including in high-risk groups such as older adults, and demonstrate significant racial and ethnic disparities. METHODS:This study considers demographic, clinical, and...

journal_title：Advances in therapy

authors： Hall LL,Xu L,Mahmud SM,Puckrein GA,Thommes EW,Chit A

更新日期：2020-05-01 00:00:00

abstract：INTRODUCTION:The 1100delC CHEK2 allele has been associated with a 1.4-to 4.7-fold increased risk of breast cancer in women carrying this mutation. Our study investigated the frequency of this allele in a Chinese population. METHODS:Using touchdown polymerase chain reaction, we sequenced the CHEK2.1100delC mutation in ...

journal_title：Advances in therapy

authors： Chen W,Yurong S,Liansheng N

更新日期：2008-05-01 00:00:00

abstract：INTRODUCTION:Subsequent lines of subcutaneous tumor necrosis factor alpha inhibitor (SC-TNFi) treatment may be well motivated in the management of rheumatoid arthritis (RA), ankylosing spondylitis (AS), and psoriatic arthritis (PsA)-collectively named inflammatory arthritis (IA). However, the costs associated with swit...

journal_title：Advances in therapy

authors： Dalén J,Luttropp K,Svedbom A,Black CM,Kachroo S

更新日期：2020-09-01 00:00:00

abstract：:This double-blind, randomized, prospective study was conducted to compare the analgesic and sedative efficacy of fentanyl and meperidine in orthopedic closed reduction of fractures and dislocations undertaken in the emergency department. Seventy consecutive adult patients with fractures or dislocations suitable for re...

journal_title：Advances in therapy

authors： Soysal S,Karcioglu O,Demircan A,Topacoglu H,Serinken M,Ozucelik N,Tirpan K,Gunerli A

更新日期：2004-09-01 00:00:00