Abstract:
:The identification of unique point mutations in patients with pseudohypoparathyroidism (PHP) with Albright's hereditary osteodystrophy (AHO) in different ethnic backgrounds has proved that defects within the Gs alpha gene account for Gs alpha deficiency in those patients. To search a mutation hot spot of the Gs alpha gene in Japanese patients, we have screened exons 2-13 of the Gs alpha gene for mutations in three unrelated Japanese PHP patients with AHO. We could find no abnormalities by denaturing gradient gel electrophoresis and no mutations of sequencing of exon 7 in these subjects. This suggests that mutations in exon 7 of the Gs alpha gene may not be a common cause of PHP with AHO in Japanese.
journal_name
Endocr Jjournal_title
Endocrine journalauthors
Takeda K,Yokoyama M,Hashimoto K,Hiromatsu Y,Yamanaka H,Shimizu T,Sasaki Mdoi
10.1507/endocrj.44.621subject
Has Abstractpub_date
1997-08-01 00:00:00pages
621-5issue
4eissn
0918-8959issn
1348-4540journal_volume
44pub_type
杂志文章abstract::Unusual presentations with bone, lung or soft tissue metastases in initial diagnosis of follicular thyroid carcinoma have been reported occasionally. This implies how difficult it is to diagnosis this type of cancer at the pre-operative or intra-operative stage of treatment. Fine needle aspiration cytology has been sh...
journal_title:Endocrine journal
pub_type: 杂志文章,评审
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更新日期:2006-08-01 00:00:00
abstract::Some categories of drugs are known for causing hyperglycemia or diabetes such as steroids, antipsychotics, and immunosuppressant. However, there has been little evidence from studies about the proportion of each drug in the context of drug-induced diabetes. In this study, we used data from the Japanese Adverse Drug Ev...
journal_title:Endocrine journal
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更新日期:2019-06-28 00:00:00
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pub_type: 杂志文章
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更新日期:2000-08-01 00:00:00
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journal_title:Endocrine journal
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doi:10.1507/endocrj.47.163
更新日期:2000-04-01 00:00:00
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doi:10.1507/endocrj.43.39
更新日期:1996-02-01 00:00:00
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journal_title:Endocrine journal
pub_type: 杂志文章
doi:10.1507/endocrj.51.435
更新日期:2004-08-01 00:00:00
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更新日期:2012-01-01 00:00:00
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journal_title:Endocrine journal
pub_type: 临床试验,杂志文章
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更新日期:1993-04-01 00:00:00
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journal_title:Endocrine journal
pub_type: 杂志文章
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pub_type: 临床试验,杂志文章
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更新日期:1993-02-01 00:00:00
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journal_title:Endocrine journal
pub_type: 杂志文章
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更新日期:2007-04-01 00:00:00
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doi:10.1507/endocrj.EJ18-0010
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doi:10.1507/endocrj.k08e-148
更新日期:2008-12-01 00:00:00
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journal_title:Endocrine journal
pub_type: 杂志文章
doi:10.1507/endocrj.k07e-024
更新日期:2008-07-01 00:00:00
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pub_type: 杂志文章,多中心研究
doi:10.1507/endocrj.45.357
更新日期:1998-06-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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journal_title:Endocrine journal
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更新日期:1993-12-01 00:00:00
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pub_type: 杂志文章
doi:10.1507/endocrj.EJ18-0166
更新日期:2018-10-29 00:00:00
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journal_title:Endocrine journal
pub_type: 杂志文章
doi:10.1507/endocrj.k10e-221
更新日期:2011-01-01 00:00:00
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journal_title:Endocrine journal
pub_type: 杂志文章
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更新日期:2013-01-01 00:00:00
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doi:10.1507/endocrj.ej12-0089
更新日期:2012-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1507/endocrj.EJ20-0024
更新日期:2020-08-28 00:00:00
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journal_title:Endocrine journal
pub_type: 杂志文章
doi:10.1507/endocrj.ej11-0157
更新日期:2012-01-01 00:00:00