A case of hypothyroidism with brugada electrocardiographic waveforms.

abstract：:Familial hypocalciuric hypercalcemia (FHH) is a benign syndrome with elevated levels of serum calcium, relative hypocalciuria, and non-suppressed serum parathyroid hormone (PTH) levels. FHH usually occurs by a heterozygous mutation of the calcium sensing receptor (Casr), but some FHH patients show no mutations of the ...

journal_title：Endocrine journal

authors： Kanazawa H,Tanaka H,Kodama S,Moriwake A,Kobayashi M,Seino Y

更新日期：2000-02-01 00:00:00

abstract：:Glucocorticoids play a critical role in the regulation of homeostasis, including metabolism. In patients with Cushing's syndrome, chronic glucocorticoid excess disrupts physiological internal milieu, resulting in central obesity, muscle atrophy, fatty liver, and insulin resistance. However, the relationship among vari...

journal_title：Endocrine journal

authors： Uehara M,Yamazaki H,Yoshikawa N,Kuribara-Souta A,Tanaka H

更新日期：2020-01-28 00:00:00

abstract：:Plasma total homocysteine (tHcy) is an independent risk factor for cardiovascular disease and increased tHcy levels have been reported to be a novel risk factor of atherosclerotic disease. The aim of this study was to assess the association of the metabolic syndrome components with plasma (tHcy) level. Total 722 parti...

journal_title：Endocrine journal

authors： Rhee EJ,Hwang ST,Lee WY,Yoon JH,Kim BJ,Kim BS,Kang JH,Lee MH,Park JR,Sung KC

更新日期：2007-12-01 00:00:00

abstract：:Hypertension and norepinephrine hypersecretion in a 59-year-old woman suffering from malignant pheochromocytoma with multiple metastases were appropriately controlled with alpha- and beta- blockers, and alpha-methyltyrosine (alpha-MT), a catecholamine-synthesis inhibitor. Metastasized vertebrae were treated with exter...

journal_title：Endocrine journal

authors： Teno S,Tanabe A,Nomura K,Demura H

更新日期：1996-10-01 00:00:00

abstract：:The amounts of immunoreactive proinsulin (IRP), immunoreactive insulin (IRI), and C-peptidelike immunoreactivity (CPR) in six insulinomas and one nesidioblastosis lesion were determined together with those in the surrounding pancreatic tissue. Four non-insulinoma and nondiabetic human pancreases were used as the contr...

journal_title：Endocrine journal

authors： Tasaka Y,Nakaya F,Matsumoto H,Odagiri R,Ohgawara H,Omori Y

更新日期：1993-04-01 00:00:00

abstract：:Reactive oxygen species (ROS) are induced under diabetic conditions and are likely associated with the development of type 2 diabetes. It is also known that ROS production is facilitated in the presence of copper ion through the Fenton reaction. The aim of this study was to examine the involvement of copper ion in the...

journal_title：Endocrine journal

authors： Tanaka A,Kaneto H,Miyatsuka T,Yamamoto K,Yoshiuchi K,Yamasaki Y,Shimomura I,Matsuoka TA,Matsuhisa M

更新日期：2009-01-01 00:00:00

abstract：:Erythropoietin (EPO) is known to stimulate erythropoiesis after binding with its specific receptor. In clinics, EPO is widely used in hemodialyzed patients with diabetes. However, changes in the expression of the erythropoietin receptor (EPOR) under diabetic conditions are still unclear. Therefore, we investigated EPO...

journal_title：Endocrine journal

authors： Kuo SC,Li Y,Cheng KC,Niu CS,Cheng JT,Niu HS

更新日期：2018-02-26 00:00:00

abstract：:Long-term management of patients with differentiated thyroid cancer (DTC) commonly includes TSH-suppressive therapy with L-T4 and, in case of postsurgical hypoparathyroidism, Calcium-D3 supplementation, both of which may affect skeletal health. Experience with female patients treated for DTC at a young age and who wer...

journal_title：Endocrine journal

authors： Leonova TA,Drozd VM,Saenko VA,Mine M,Biko J,Rogounovitch TI,Takamura N,Reiners C,Yamashita S

更新日期：2015-01-01 00:00:00

abstract：:A patient with an apparently normal 46, XY karyotype, suffering from pure gonadal dysgenesis and of short stature was investigated. The patient, who was growth retarded, was a 30-year-old married Japanese woman with a history of primary amenorrhea and infertility with a weight of 42 kg and a height of 146 cm. She has ...

journal_title：Endocrine journal

authors： Tsutsumi O,Iida T,Taketani Y,Sugase M,Nakahori Y,Nakagome Y

更新日期：1994-06-01 00:00:00

abstract：:The renin-angiotensin system (RAS) has been unequivocally implicated as a mediator of diabetic complications. The present study was designed to evaluate the RAS in non-insulin dependent diabetic patients with diabetic nephropathy. Plasma renin activity, plasma angiotensin II and serum angiotensin-converting enzyme (AC...

journal_title：Endocrine journal

authors： Nicola W,Sidhom G,El Khyat Z,Ibrahim S,Salah A,El Sayed A

更新日期：2001-02-01 00:00:00

abstract：:We aimed to explore whether common allelic variations in the SIRT1 gene were associated with excess body weight in a Chinese cohort. Using standard molecular techniques 820 non-diabetic individuals, some of who were classified as overweight (> 23 Kg/m(2)), were genotyped for four haplotype-tagged single nucleotide po...

journal_title：Endocrine journal

authors： Zheng J,Chen LL,Xiao F,Hu X,Deng X,Li H

更新日期：2012-01-01 00:00:00

abstract：:Estrogen has been shown to stimulate lactotroph proliferation and expression of the prolactin (PRL) gene. Recently it has been established that Pit-1, a pituitary-specific transcription factor, is required for lactotroph proliferation. Furthermore, in vitro studies showed that an increase in the PRL promoter activity ...

journal_title：Endocrine journal

authors： Tsukahara S,Kambe F,Suganuma N,Tomoda Y,Seo H

更新日期：1994-10-01 00:00:00

abstract：:Diabetic foot ulcer is a chronic, refractory, frequent complication in diabetic patient. Its treatment often requires multidisciplinary joint efforts, diverse strategies have been adopted to address this annoying issue, including stem cell-based therapy/acellular dermal matrix/negative pressure wound therapy etc. Howe...

journal_title：Endocrine journal

authors： Shu X,Shu S,Tang S,Yang L,Liu D,Li K,Dong Z,Ma Z,Zhu Z,Din J

更新日期：2018-04-26 00:00:00

abstract：OBJECTIVE:The purpose of this study was to assess the rate of malignancy in thyroid nodules incidentally detected at sonography and to determine the diagnostic value of ultrasonography-guided fine needle aspiration cytology (USgFNAC) in thyroid nodules. METHODS:Five hundred patients (84 men and 416 women) who had thyr...

journal_title：Endocrine journal

authors： Kim DL,Song KH,Kim SK

更新日期：2008-03-01 00:00:00

abstract：:Immunoreactive activin A (ir-activin A) release from cultured rat anterior pituitary cells was examined by measuring ir-activin A in culture medium by a specific radioimmunoassay. Ir-activin A release into the medium increased over 1-18 days, and reached a maximal level at 12-15 days. The basal levels of ir-activin A ...

journal_title：Endocrine journal

authors： Liu ZH,Shintani Y,Wakatsuki M,Sakamoto Y,Harada K,Zhang CY,Saito S

更新日期：1996-02-01 00:00:00

abstract：:The neurohypophysial hormone, oxytocin, is involved in the regulation of energy metabolism. Adiponectin (APN) is an adipose tissue-specific serum protein that inversely associates with metabolic syndrome (MetS). High-molecular-weight adiponectin (HMW APN) is considered the active form. In the present study, we aimed t...

journal_title：Endocrine journal

authors： Yuan G,Qian W,Pan R,Jia J,Jiang D,Yang Q,Wang S,Liu Y,Yu S,Hu H,Sun W,Ye J,Mao C,Zhuang R,Zhou L

更新日期：2016-07-30 00:00:00

abstract：:The relation between thyroid ultrasonography and laboratory, and the relationship of thyroid volume with clinical and anthropometric parameters, are not well clarified. Aim of the study was to investigate normal and hypoechoic-inhomogeneous not nodular thyroid gland in predicting thyroid tests, and to assess the corre...

journal_title：Endocrine journal

authors： Trimboli P,Rossi F,Thorel F,Condorelli E,Laurenti O,Ventura C,Nigri G,Romanelli F,Guarino M,Valabrega S

更新日期：2012-01-01 00:00:00

abstract：:While patients with large goitrous thyroid diseases often have a relatively high serum free triiodothyronine (FT3)/free thyroxine (FT4) ratio, athyreotic patients have a relatively low FT3/FT4 ratio. Here we investigated the relationship between thyroid hormone status and thyroid volume (TV) among a large number of eu...

journal_title：Endocrine journal

authors： Kawasaki M,Ito M,Danno H,Kousaka K,Nakamura T,Yoshioka W,Kasahara T,Kudo T,Nishihara E,Fukata S,Nishikawa M,Nakamura H,Toyoda N,Miyauchi A

更新日期：2019-09-28 00:00:00

abstract：:We report a de novo heterozygous 5,013,940 bp terminal deletion of chromosome 15q26 in a 13 9/12 -year-old Japanese girl with short stature (-3.9 SD), mild mental retardation, and ventricular septal defect (VSD). This terminal deletion involved IGF1R but not NR2F2, and was associated with an addition of telomere repea...

journal_title：Endocrine journal

authors： Dateki S,Fukami M,Tanaka Y,Sasaki G,Moriuchi H,Ogata T

更新日期：2011-01-01 00:00:00

abstract：:The aim of this study was to assess the effect of the long-term different diabetic therapies on the plasma leptin level in type 2 diabetic subjects. We measured plasma leptin, body fat and fasting plasma insulin in 96 type 2 diabetic male subjects. They had received the same treatment regimen for more than one year (3...

journal_title：Endocrine journal

authors： Huang CC,Lin JD,Chang HY

更新日期：2001-06-01 00:00:00

abstract：:In this study, we investigated the difference in lymph node-recurrence free survival (LN-RFS), distant recurrence-free survival (DRFS), and cause-specific survival (CSS) between patients with papillary thyroid carcinoma (PTC) in the entire group (Group I) and those with lymph node- and distant-recurrence-free survival...

journal_title：Endocrine journal

authors： Ito Y,Kudo T,Kihara M,Takamura Y,Kobayashi K,Miya A,Miyauchi A

更新日期：2012-01-01 00:00:00

abstract：:We evaluated the influence of short-term treatment with exenatide twice daily or liraglutide once daily on daily blood glucose fluctuations in 40 patients with type 2 diabetes inadequately controlled by sulfonylureas. The patients in a multicenter, open-label trial were randomly assigned to receive add-on exenatide (1...

journal_title：Endocrine journal

authors： Nagakura J,Yamakawa T,Taguri M,Tsuchiya H,Shigematsu E,Suzuki J,Morita S,Kadonosono K,Terauchi Y

更新日期：2016-01-01 00:00:00

abstract：:The human endometrium undergoes cyclical changes including proliferation, differentiation, tissue breakdown, and shedding (menstruation) throughout a woman's reproductive life. The postovulatory rise in ovarian progesterone induces profound remodeling and differentiation of the estradiol-primed endometrium. This chang...

journal_title：Endocrine journal

authors： Maruyama T,Yoshimura Y

更新日期：2008-10-01 00:00:00

abstract：:As a rare condition characterized by inflammation of the pituitary gland, hypophysitis usually results in hypopituitarism and pituitary enlargement. The most critical outcome of hypopituitarism is caused by secondary adrenal insufficiency. Glucocorticoid deficiency is a life-threatening condition, and patients who dev...

journal_title：Endocrine journal

authors： Aikawa E,Horie I,Naganobu K,Nozaki A,Kamada A,Abiru N,Kawakami A

更新日期：2020-11-28 00:00:00

abstract：:Central diabetes insipidus (CDI) is characterized by polyuria and polydipsia caused by impairment of arginine vasopressin (AVP) secretion. In this study, we evaluated plasma AVP concentrations during a hypertonic saline infusion test using a new AVP radioimmunoassay (RIA) which is now available in Japan. Thirteen cont...

journal_title：Endocrine journal

authors： Takagi H,Hagiwara D,Handa T,Sugiyama M,Onoue T,Tsunekawa T,Ito Y,Iwama S,Goto M,Suga H,Banno R,Takahashi K,Matsui S,Arima H

更新日期：2020-03-28 00:00:00

abstract：:As 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) is becoming a common imaging modality, the number of thyroid incidentalomas identified by FDG-PET (PET incidentaloma) is increasing. The purpose of this study was to elucidate the risk of cancer in focal thyroid PET incidentaloma in healthy subjects of...

journal_title：Endocrine journal

authors： Ohba K,Nishizawa S,Matsushita A,Inubushi M,Nagayama K,Iwaki H,Matsunaga H,Suzuki S,Sasaki S,Oki Y,Okada H,Nakamura H

更新日期：2010-01-01 00:00:00

abstract：:The effect of prolonged diabetes on epinephrine-induced adenosine 3',5'-monophosphate (cAMP) response in the liver was examined in diabetes-prone BB/W rats. Basal and 1 microM epinephrine-induced cAMP release from isolated perfused liver was similar in non-diabetic and diabetic BB/W rats with preserved adipose tissue....

journal_title：Endocrine journal

authors： Yamatani K,Saito K,Ohnuma H,Ikezawa Y,Seino T,Manaka Y,Daimon M,Takahashi K,Sasaki H

更新日期：1997-10-01 00:00:00

abstract：:In an attempt to define the hypothalamic-pituitary-adrenal (HPA) axis in non-insulin dependent diabetic rats (WBN/Kob), we measured plasma corticotropin releasing factor (CRF), as well as arginine vasopressin (AVP), ACTH, and corticosterone (B), CRF concentrations in the median eminence (ME), the remainder of the hypo...

journal_title：Endocrine journal

authors： Tojo C,Takao T,Nishioka T,Numata Y,Suemaru S,Hashimoto K

更新日期：1996-04-01 00:00:00

abstract：:We examined 13 patients with euthyroid Graves' disease suspected ophthalmologically, by comparing them with 20 patients with untreated Graves' disease and by following them up for 5 to 10 years. They had Graves' ophthalmopathy (NOSPECS class II-IV) without other ocular diseases, normal levels of serum thyroid hormones...

journal_title：Endocrine journal

authors： Kashiwai T,Tada H,Asahi K,Hidaka Y,Tamaki H,Iwatani Y,Amino N

更新日期：1995-06-01 00:00:00

abstract：:Plasma CRH levels were measured in patients with non-insulin dependent diabetes mellitus (NIDDM) as the pituitary-adrenal abnormalities have been reported in NIDDM. They were also measured after oral administration of 75 g glucose to examine whether glucose increased plasma CRH along with insulin secretion. The baseli...

journal_title：Endocrine journal

authors： Hashimoto K,Nishioka T,Takao T,Numata Y

更新日期：1993-12-01 00:00:00