The effect of calcium-sensing receptor gene polymorphisms on serum calcium levels: a familial hypocalciuric hypercalcemia family without mutation in the calcium-sensing receptor gene.

abstract：:Parathyroidectomy (PTX) is the standard treatment for secondary hyperparathyroidism (SHPT); however, the administration of cinacalcet has gained prominence as a noninvasive treatment. We aimed to determine whether PTX or cinacalcet is more effective in preventing morbidity and mortality through reviewing follow-up dat...

journal_title：Endocrine journal

authors： Kim WW,Rhee Y,Kim BS,Kim K,Lee CR,Kang SW,Lee J,Jeong JJ,Nam KH,Chung WY

更新日期：2019-10-28 00:00:00

abstract：:Nesfatin-1 is a polypeptide derived from the posttranslational processing of the N-terminal fragment of nucleobindin 2 (NUCB2), that was originally identified as an anorexigenic hypothalamic neuropeptide. A number of reports have recently shown that NUCB2/nesfatin-1 is widely expressed in various peripheral tissues, i...

journal_title：Endocrine journal

authors： Cao X,Liu XM,Zhou LH

更新日期：2013-01-01 00:00:00

abstract：:As 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) is becoming a common imaging modality, the number of thyroid incidentalomas identified by FDG-PET (PET incidentaloma) is increasing. The purpose of this study was to elucidate the risk of cancer in focal thyroid PET incidentaloma in healthy subjects of...

journal_title：Endocrine journal

authors： Ohba K,Nishizawa S,Matsushita A,Inubushi M,Nagayama K,Iwaki H,Matsunaga H,Suzuki S,Sasaki S,Oki Y,Okada H,Nakamura H

更新日期：2010-01-01 00:00:00

abstract：:Maternal Graves' disease (GD) during pregnancy may influence thyroid function in fetuses. Neonates born to mothers with high serum TSH receptor antibody (TRAb) levels have been reported to develop 'neonatal GD'. Therefore, evaluations of serum thyroid hormone and TRAb levels in neonates upon birth are crucial for a pr...

journal_title：Endocrine journal

authors： Wada M,Kita M,Kawasaki K,Kusakabe T,Tagami T,Satoh-Asahara N,Shimatsu A,Hashimoto K

更新日期：2018-05-28 00:00:00

abstract：:The effect of luteinizing hormone releasing hormone (LHRH) on the neuronal activity of CA1 and CA3 regions of the hippocampus was studied by means of extracellular recordings in the castrated male, intact male, castrated female, and castrated female injected s.c. with 20 micrograms estradiol benzoate (EB) for 3 days. ...

journal_title：Endocrine journal

authors： Osada T,Kimura F

更新日期：1995-04-01 00:00:00

abstract：:Late-night salivary cortisol (NSC) has been recognized as a sensitive and easy-to-perform screening test for the diagnosis of overt Cushing's syndrome (CS). However, there have been few reports on the diagnostic utility of salivary cortisol (SC) measurement in the diagnosis of subclinical Cushing's syndrome (SCS). T...

journal_title：Endocrine journal

authors： Tateishi Y,Kouyama R,Mihara M,Doi M,Yoshimoto T,Hirata Y

更新日期：2012-01-01 00:00:00

abstract：:It has been suggested that metabolic syndrome (MetS) overlaps prediabetes and type 2 diabetes and that it is not necessary to consider it as a separate clinical entity. In the present study, patients with normoglycemia and dysglycemia were compared in terms of MetS frequency and MetS criteria characteristics, in order...

journal_title：Endocrine journal

authors： Uzunlulu M,Oguz A

更新日期：2007-12-01 00:00:00

abstract：:The management of occult small thyroid nodules found by ultrasonography is sometimes problematic. Self-palpation may be utilized in the follow-up of these nodules. We developed a method of thyroid self-examination (TSE). We examined the size of the nodules palpable by this method by ultrasonography. In 78 patients exa...

journal_title：Endocrine journal

authors： Takano T,Hasegawa Y,Amino N

更新日期：2000-10-01 00:00:00

abstract：:Troglitazone (T) and d-chiroinositol (DCI) have been reported to improve insulin resistance associated with obesity and NIDDM. We tested whether these compounds counteract the insulin antagonistic effects of recombinant human GH. Male Wistar rats were allocated to 4 different treatment groups, rhGH (n=8), rhGH+T (n=7)...

journal_title：Endocrine journal

authors： Sugimoto M,Takeda N,Hattori J,Yoshino K,Nakashima K,Okumura S,Ishimori M,Yasuda K

更新日期：1999-03-01 00:00:00

abstract：:Musk is a secreted external hormone or information compound that is stored in musk scent glands of the males of species within the family Moschidae, such as Moschus berezovskii. The secretion of musk changes periodically during the courtship and reproduction periods, with the early stage of secretion occurring from Ma...

journal_title：Endocrine journal

authors： Fan M,Zhang M,Shi M,Zhang T,Qi L,Yu J,Li X,Lin S,Huang Z,Yang S,Zhou J,Li Y,Sun X,Cha M,Xu S,Liu Y,Guo X,Hu D,Liu S

更新日期：2018-11-29 00:00:00

abstract：:Metabolic syndrome (MetS) is the occurrence of diabetes mellitus/glucose intolerance, arterial hypertension, central obesity, dyslipidemia, and microalbuminuria in the same patient (definition by WHO). Presence of metabolic syndrome is associated with larger myocardial infarction size and complications following acut...

journal_title：Endocrine journal

authors： Kranjcec D,Altabas V

更新日期：2012-01-01 00:00:00

abstract：:Diarrhea is a non-specific symptom which may be associated with Addison's disease and several causes had been demonstrated in the aetiology. We describe a patient with Addison's disease who was suffering from chronic diarrhea for three months. She was diagnosed as having collagenous colitis and successfully treated wi...

journal_title：Endocrine journal

authors： Unlühizarci K,Bayram F,Ozbakir O,Kirgin A,Patiroglu T,Yücesoy M,Keleştimur F

更新日期：1998-08-01 00:00:00

abstract：:Sexual differentiation of the rodent brain is recognized to involve transcriptional activation of multiple genes induced by gonadal steroids at developmental stages. To identify the genes differing in expression level between sexes, we analyzed gene expression in male and female rat hypothalami at postnatal day 5 by m...

journal_title：Endocrine journal

authors： Yonehara K,Suzuki M,Nishihara M

更新日期：2002-04-01 00:00:00

abstract：:Plasma total homocysteine (tHcy) is an independent risk factor for cardiovascular disease and increased tHcy levels have been reported to be a novel risk factor of atherosclerotic disease. The aim of this study was to assess the association of the metabolic syndrome components with plasma (tHcy) level. Total 722 parti...

journal_title：Endocrine journal

authors： Rhee EJ,Hwang ST,Lee WY,Yoon JH,Kim BJ,Kim BS,Kang JH,Lee MH,Park JR,Sung KC

更新日期：2007-12-01 00:00:00

abstract：:In recent times, the role of fibroblast growth factor 21 (FGF21) in patients with gestational diabetes mellitus (GDM) has been increasingly investigated. However, to our knowledge, no systematic analysis has been conducted yet to evaluate the relationship between FGF21 levels and GDM. Confirmed studies related to circ...

journal_title：Endocrine journal

authors： Jia J,Wei W,Yu F,Liu R,Shen Y,Zhang R,Yuan G,Zhou H

更新日期：2020-11-06 00:00:00

abstract：:Metabolic syndrome is a common disorder in Taiwan. For this study 431 subjects were randomly selected from visitors to the Department of Health Management. Blood pressure, blood glucose, lipid, uric acid levels and anthropometric measurements with immunoreactive insulin (IRI) and leptin levels were all correlated. We ...

journal_title：Endocrine journal

authors： Chiou WK,Lin JD,Weng HF,Ou YC,Liu TH,Fang JT

更新日期：2005-02-01 00:00:00

abstract：:Hypophysitis, which is often accompanied by pituitary dysfunction, is classified into several subtypes based on the cause, histology, and the location of inflammation in the pituitary gland. A definitive diagnosis requires pituitary biopsy, which is invasive, and the process is limited to specialized clinical settings...

journal_title：Endocrine journal

authors： Takagi H,Iwama S,Sugimura Y,Takahashi Y,Oki Y,Akamizu T,Arima H

更新日期：2020-04-28 00:00:00

abstract：:Long-term management of patients with differentiated thyroid cancer (DTC) commonly includes TSH-suppressive therapy with L-T4 and, in case of postsurgical hypoparathyroidism, Calcium-D3 supplementation, both of which may affect skeletal health. Experience with female patients treated for DTC at a young age and who wer...

journal_title：Endocrine journal

authors： Leonova TA,Drozd VM,Saenko VA,Mine M,Biko J,Rogounovitch TI,Takamura N,Reiners C,Yamashita S

更新日期：2015-01-01 00:00:00

abstract：:Antipituitary antibody (APA) has been reported to be detected in patients with autoimmune thyroid disease. Type 2 iodothyronine deiodinase (D2) is expressed in both pituitary gland and thyroid gland. We studied the association of APA and D2 peptide antibody in patients with autoimmune thyroid disease. Rat pituitary gl...

journal_title：Endocrine journal

authors： Nakahara R,Tsunekawa K,Yabe S,Nara M,Seki K,Kasahara T,Ogiwara T,Nishino M,Kobayashi I,Murakami M

更新日期：2005-12-01 00:00:00

abstract：:We examined the effects of the long-term administration to mice of thyroid hormone or propylthiouracil (PTU) on lymphocyte subsets in spleens, and thymuses to clarify whether hyperthyroxinemia itself causes the changes in lymphocyte subsets, such as the marked increase in CD5+ B cells and decrease in natural killer (N...

journal_title：Endocrine journal

authors： Watanabe K,Iwatani Y,Hidaka Y,Watanabe M,Amino N

更新日期：1995-10-01 00:00:00

abstract：:The neurohypophysial hormone, oxytocin, is involved in the regulation of energy metabolism. Adiponectin (APN) is an adipose tissue-specific serum protein that inversely associates with metabolic syndrome (MetS). High-molecular-weight adiponectin (HMW APN) is considered the active form. In the present study, we aimed t...

journal_title：Endocrine journal

authors： Yuan G,Qian W,Pan R,Jia J,Jiang D,Yang Q,Wang S,Liu Y,Yu S,Hu H,Sun W,Ye J,Mao C,Zhuang R,Zhou L

更新日期：2016-07-30 00:00:00

abstract：:Medullary thyroid carcinoma (MTC) may mimic mixed medullary and follicular thyroid carcinoma (MMFTC). MTC originates from para-follicular cells, while MMFTC is an uncommon tumor characterized by coexistence of follicular and para-follicular cell-derived tumor populations. A 35-year-old woman was diagnosed with MTC but...

journal_title：Endocrine journal

authors： Takeshima K,Ariyasu H,Uraki S,Morita S,Furukawa Y,Inaba H,Iwakura H,Doi A,Warigaya K,Murata SI,Enomoto K,Hotomi M,Akamizu T

更新日期：2020-10-28 00:00:00

abstract：:We studied the cross-sectional relationship between GA and HbA1c in 142 type 2 diabetic patients who had an HbA1c level < 7.5% for at least one year without fluctuation by more than 0.5%. We also followed the changes of GA and HbA1c in 18 type 2 diabetic patients for 16 weeks as they progressed from untreated severe h...

journal_title：Endocrine journal

authors： Takahashi S,Uchino H,Shimizu T,Kanazawa A,Tamura Y,Sakai K,Watada H,Hirose T,Kawamori R,Tanaka Y

更新日期：2007-02-01 00:00:00

abstract：:Patients with growth hormone (GH) deficiency (GHD) have a clinical feature of visceral adiposity and it has been reported that these patients have an increased active cortisol (F)/inactive cortisone (E) metabolite ratio. 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) is an enzyme expressed in liver and adipo...

journal_title：Endocrine journal

authors： Morita J,Hakuno F,Hizuka N,Takahashi S,Takano K

更新日期：2009-01-01 00:00:00

abstract：:In this study, we evaluated the association between bone mineral density (BMD) and 10 single-nucleotide polymorphisms (SNPs) within eight osteoporosis susceptibility genes that were previously identified in genome-wide association studies (GWASs). A total of 494 men and 493 postmenopausal women participating in the Ch...

journal_title：Endocrine journal

authors： Park SE,Oh KW,Lee WY,Baek KH,Yoon KH,Son HY,Lee WC,Kang MI

更新日期：2014-01-01 00:00:00

abstract：:Thyrotoxic periodic paralysis (TPP) is mainly associated with Graves' disease but rarely with autonomously functioning thyroid nodule (AFTN). We herein report a case of AFTN associated with TPP in which the latter resolved after (131) I therapy for the former. We analyzed the genes encoding thyrotropin receptor (TSHR)...

journal_title：Endocrine journal

authors： Ozaki H,Mori K,Nakagawa Y,Hoshikawa S,Ito S,Yoshida K

更新日期：2008-03-01 00:00:00

abstract：:Metabolic disorders, such as PCOS (polycystic ovarian syndrome) and T2DM (type 2 diabetes mellitus), are associated with menstrual dysfunction, anovulation, infertility, and early pregnancy loss. Ovarian dysfunction is not only related to low pregnancy rates but also to the increased risk of miscarriage. Women with PC...

journal_title：Endocrine journal

authors： Su Y,Wu J,He J,Liu X,Chen X,Ding Y,Zhang C,Chen W,Wang Y,Gao R

更新日期：2017-06-29 00:00:00

abstract：:A 14-year-old girl was referred to our department because of headache and visual impairment following the resection of recurrent cardiac myxoma. Head magnetic resonance imaging (MRI) scan detected an intra- and supra-sellar tumor. Moreover, the patient showed the presence of spotty skin pigmentations on her cheeks and...

journal_title：Endocrine journal

authors： Naito Y,Mori J,Tazoe J,Tomida A,Yagyu S,Nakajima H,Iehara T,Tatsuzawa K,Mukai T,Hosoi H

更新日期：2019-12-25 00:00:00

abstract：:Although subacute thyroiditis (de Quervain's thyroiditis) is presumed to be caused by a viral infection, only 2 familial occurrences of subacute thyroiditis have been reported in the literature. Typical and severe subacute thyroiditis was diagnosed in an older sister who was hospitalized for 8 days. During this period...

journal_title：Endocrine journal

authors： Kabalak T,Ozgen AG

更新日期：2002-04-01 00:00:00

abstract：:Postprandial hyperglycemia and/or hyperlipidemia can contribute to development of atherosclerosis in patients with type 2 diabetes mellitus (T2DM). The objective of this study was to compare the effects of miglitol and sitagliptin on postprandial glucose and lipid metabolism in patients with T2DM. Thirty-five patients...

journal_title：Endocrine journal

authors： Okada K,Yagyu H,Kotani K,Yamazaki H,Ozaki K,Takahashi M,Nagashima S,Osuga J,Ishibashi S

更新日期：2013-01-01 00:00:00