Integrated radiosurgical treatment of resectable pancreatic head carcinoma.

abstract：OBJECTIVES:Cigarette smoking is an independent risk factor for chronic pancreatitis. We conducted a systematic review of the literature assessing whether cigarette smoking is a risk factor for acute pancreatitis (AP) and recurrent AP (RAP). METHODS:MEDLINE, PubMed, Embase, and Cochrane Database of Systematic Reviews w...

journal_title：Pancreas

authors： Majumder S,Gierisch JM,Bastian LA

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVES:This study aimed to investigate the frequency, predictors, and management of relapse of type 1 autoimmune pancreatitis (AIP) after steroid treatment. METHODS:One hundred one patients with type 1 AIP receiving steroid as initial treatment were enrolled. Predictors were identified by multivariate analysis usi...

journal_title：Pancreas

authors： Xin L,Meng QQ,Hu LH,Lin H,Pan J,Hao L,Liu PP,Qian W,Wang LW,Li ZS

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVE:This study aimed to investigate whether the previously described differentiating islet-like aggregates of human pancreatic adenocarcinoma cells (PANC-1) develop glucose response and exhibit intercellular communication. METHODS:Fura 2-loaded PANC-1 cells in serum-free medium were assayed for changes in cytoso...

journal_title：Pancreas

authors： Hiram-Bab S,Shapira Y,Gershengorn MC,Oron Y

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVE:Pancreatic ductal adenocarcinoma (PDAC) is the third most common cause of cancer death in the United States. Improved characterized models of PDAC are needed for drug screening. METHODS:We grew 4 established pancreatic cancer cell lines in hanging drop cultures to produce spheroids. We also grew organoids fr...

journal_title：Pancreas

authors： Matsushita Y,Smith B,Delannoy M,Trujillo MA,Chianchiano P,McMillan R,Kamiyama H,Liang H,Thompson ED,Hruban RH,Matsui W,Wood LD,Roberts NJ,Eshleman JR

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to assess the association of hemodynamic factors with 90-day mortality in critically ill patients with severe acute pancreatitis (SAP). METHODS:One hundred fifty-nine consecutive patients with SAP admitted to the intensive care units between January 2005 and December 2008 were incl...

journal_title：Pancreas

authors： Wilkman E,Kaukonen KM,Pettilä V,Kuitunen A,Varpula M

更新日期：2013-03-01 00:00:00

abstract：:The effects of manganese (Mn2+) on phosphorylation activity in the rat pancreas were examined in an in vitro phosphorylation assay and by sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) of endogenous proteins. Several histones were phosphorylated in the presence of pancreatic supernatant obtained ...

journal_title：Pancreas

authors： Brockenbrough JS,Korc M

更新日期：1990-09-01 00:00:00

abstract：:Serum expression of the cancer-associated antigens CA 19-9 and CA 50 and their relation to Lewis blood cell status were studied in 26 patients with pancreatic duct carcinoma and 26 patients with pancreatitis. The discriminating capacity between benign and malignant disease was high for both tumor markers. The correspo...

journal_title：Pancreas

authors： von Rosen A,Linder S,Harmenberg U,Pegert S

更新日期：1993-03-01 00:00:00

abstract：OBJECTIVES:Regeneration of the pancreas is initiated by the tubular complexes that consist of a cluster of epithelia surrounded by the mesenchymal cells. They have the potential to become pancreatic lobes, but their growth stops before the complete regeneration of the organ. To elucidate the possibility that we could p...

journal_title：Pancreas

authors： Kitamura T,Asanuma N,Inaba M,Otsuki M,Kasayama S,Kouhara H,Kawase I

更新日期：2005-03-01 00:00:00

abstract：:The transport specificity of L-glutamine influx in the perfused rat exocrine pancreas has been investigated using a dual isotope tracer dilution technique. During a single circulation through the isolated pancreas, an epithelial uptake of 71 +/- 1% (n = 10) was measured for L-(3H)glutamine relative to the extracellula...

journal_title：Pancreas

authors： Mann GE,Habara Y,Peran S

更新日期：1986-01-01 00:00:00

abstract：:We diverted bile and pancreatic juice from jejunal blind loops of different lengths in conscious rats to see if the pancreatic secretory response was dependent on the length of the jejunal blind loop. Short-term bile and pancreatic juice diversion from a short jejunal blind loop, representing only 8-10% of the total l...

journal_title：Pancreas

authors： Spannagel AW,Green GM

更新日期：1999-01-01 00:00:00

abstract：:Pancreatic carcinoma is one of the most devastating neoplasms with regard to its resistance to conventional therapy. In a previous report, we found that endogenous tumor necrosis factor (enTNF) exerts an intracellular protective effect against exogenous TNF- and Adriamycin (ADM)-induced cytotoxicity by scavenging oxyg...

journal_title：Pancreas

authors： Watanabe N,Tsuji N,Tsuji Y,Sasaki H,Okamoto T,Akiyama S,Kobayashi D,Sato T,Yamauchi N,Niitsu Y

更新日期：1996-11-01 00:00:00

abstract：:We examined whether pancreas grafts preserved by the two-layer method maintained adenine nucleotides pool as substrates for ATP synthesis before reperfusion and had the ability to recover pancreatic tissue perfusion and synthesize ATP promptly after reperfusion. After preservation by the two-layer cold storage method ...

journal_title：Pancreas

authors： Kim Y,Kuroda Y,Tanioka Y,Matsumoto S,Fujita H,Sakai T,Hamano M,Suzuki Y,Ku Y,Saitoh Y

更新日期：1997-04-01 00:00:00

abstract：OBJECTIVES:The aims of this study were to evaluate diagnostic value of endoscopic ultrasound strain ratio elastography in patients with focal pancreatic masses and to determine the cutoff value between the pancreatic malignancies and inflammatory pancreatic masses using reference areas different than those used by othe...

journal_title：Pancreas

authors： Rustemović N,Kalauz M,Grubelić Ravić K,Iveković H,Bilić B,Ostojić Z,Opačić D,Ledinsky I,Majerović M,Višnjić A

更新日期：2017-03-01 00:00:00

abstract：:Chemoprevention by a synthetic retinoid, selenium, and these agents in combination during the postinitiation stages of carcinogenesis induced in rats by azaserine was evaluated. Male Lewis rats were given three weekly injections of 30 mg/kg azaserine while being fed a purified diet. One week after completion of carcin...

journal_title：Pancreas

authors： Curphey TJ,Kuhlmann ET,Roebuck BD,Longnecker DS

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVES:To investigate the inhibition of PANC-1 pancreatic cancer cell growth by cucurmosin (CUS) and its possible mechanism. METHODS:We observed the inhibition of PANC-1 cell growth by sulforhodamine B and colony-forming experiments in vitro and established nonobese diabetic/severe combined immunodeficiency mouse ...

journal_title：Pancreas

authors： Wang C,Yang A,Zhang B,Yin Q,Huang H,Chen M,Xie J

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVE:There is reluctance to use donation after cardiac death (DCD) organs for fear of worse outcomes due to increased warm ischemia time. Extensive evidence to confirm the quality of DCD pancreas transplants is not manifest. METHODS:A united network for organ sharing database review of pancreas transplants perfor...

journal_title：Pancreas

authors： Siskind E,Akerman M,Maloney C,Huntoon K,Alex A,Siskind T,Bhaskeran M,Ali N,Basu A,Molmenti E,Ortiz J

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVES:The median age of patients with pancreatic ductal adenocarcinoma (PDAC) is approximately 70 years, and PDAC rarely affects individuals younger than 40 years. Here, we investigated clinicopathologic features and genetic background of PDAC occurring in young patients (age ≤ 40 years) to determine whether any d...

journal_title：Pancreas

authors： Ohmoto A,Yachida S,Kubo E,Takai E,Suzuki M,Shimada K,Okusaka T,Morizane C

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVES:To correlate magnetic resonance cholangiopancreatography (MRCP) and magnetic resonance imaging (MRI) findings of the pancreas with the pancreatic exocrine function determined by fecal elastase 1 concentration. METHODS:Magnetic resonance imaging and MRCP findings of 81 consecutive patients with clinically su...

journal_title：Pancreas

authors： Bilgin M,Bilgin S,Balci NC,Momtahen AJ,Bilgin Y,Klör HU,Rau WS

更新日期：2008-01-01 00:00:00

abstract：:In a patient with pancreatic cancer, an arterial anomaly was observed that apparently consisted of the congenital absence of the celiac axis and the replacement of the pancreaticoduodenal arcade by an anomalous vessel. The complete or near-complete arterial flow to the liver and spleen depended upon this anomalous pre...

journal_title：Pancreas

authors： Howard JM,Woldenberg LS,Conover SV

更新日期：1989-01-01 00:00:00

abstract：:Although surgical procedures that improve pancreatic drainage alleviate abdominal pain in the vast majority of patients with chronic pancreatitis, postoperative absorption and nutritional status are less predictable. The present study was designed to determine the efficacy of pancreatic enzyme supplementation in maint...

journal_title：Pancreas

authors： Van Hoozen CM,Peeke PG,Taubeneck M,Frey CF,Halsted CH

更新日期：1997-03-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to establish a minimally invasive and simple screening test for detection of pancreatic ductal adenocarcinoma (PDAC) using duodenal juice (DJ). METHODS:Duodenal juice was collected prospectively before endoscopic retrograde cholangiopancreatography in 46 patients. A protease inhibi...

journal_title：Pancreas

authors： Mori Y,Ohtsuka T,Kono H,Nagayoshi Y,Ideno N,Aso T,Kozono S,Ohuchida K,Takahata S,Nakamura M,Mizumoto K,Tanaka M

更新日期：2013-03-01 00:00:00

abstract：:Relative adrenal insufficiency is common in patients with severe sepsis and septic shock. We describe three patients with severe acute pancreatitis who developed signs suggestive of adrenal insufficiency during the early phase of the disease. Clinical features and possible causes of adrenal insufficiency are discussed...

journal_title：Pancreas

authors： De Waele JJ,Hoste E,Decruyenaere J,Colardyn F

更新日期：2003-10-01 00:00:00

abstract：:The effects of a specific cholecystokinin (CCK) receptor antagonist (L364,718) and a gastrin receptor antagonist (L365,260) on gastrin-releasing peptide-10 (GRP-10)-stimulated pancreatic secretion were investigated in the anesthetized rat. GRP-10 stimulated pancreatic exocrine secretion in a dose-dependent manner. A d...

journal_title：Pancreas

authors： Terashima H,Debas HT,Bunnett NW

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVES:To investigate the performance of erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) for predicting severe acute pancreatitis (AP). METHODS:Fifty patients with AP were prospectively enrolled. Erythrocyte sedimentation rate and CRP were measured at admission and every 12 hours for 48 hours aft...

journal_title：Pancreas

authors： Pongprasobchai S,Jianjaroonwong V,Charatcharoenwitthaya P,Komoltri C,Tanwandee T,Leelakusolvong S,Pausawasdi N,Srikureja W,Chainuvati S,Prachayakul V,Manatsathit S,Kachintorn U

更新日期：2010-11-01 00:00:00

abstract：:Genistein is a plant isoflavonoid bearing potent tumor growth-regulating characteristics. This effect of genistein has been attributed partially to its tyrosine kinase-regulating properties, resulting in cell-cycle arrest and limited angiogenesis. Genistein has been used in chemotherapy-resistant cases of advanced leu...

journal_title：Pancreas

authors： Boros LG,Bassilian S,Lim S,Lee WN

更新日期：2001-01-01 00:00:00

abstract：:It has recently been shown that the infusion of oleic acid into the rat pancreaticobiliary duct causes a reproducible and long-lasting atrophy of the exocrine pancreas. The effects of this pancreatic atrophy on non-invasive pancreatic function tests have not been fully characterized. This study was undertaken to deter...

journal_title：Pancreas

authors： Henry JP,Steinberg WM

更新日期：1993-09-01 00:00:00

abstract：OBJECTIVES:To evaluate the systemic effects of moderate hypothermia (MH) and the timing of induction on acute pancreatitis (AP) and endotoxemia in rats. METHODS:The effects of MH were compared in 4 groups, that is, sham group (38 degrees C), control group (38 degrees C), early MH group (32 degrees C on administration ...

journal_title：Pancreas

authors： Fujimoto K,Fujita M,Tsuruta R,Tanaka R,Shinagawa H,Izumi T,Kasaoka S,Maekawa T

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVE:To develop a ¹³C-labeled substrate breath test by defining the optimal ¹³C-labeled substrate, substrate dose, test meal, and duration of the test and evaluating its accuracy for the diagnosis of pancreatic exocrine insufficiency (PEI) in chronic pancreatitis (CP). METHODS:Five consecutive prospective compara...

journal_title：Pancreas

authors： Domínguez-Muñoz JE,Nieto L,Vilariño M,Lourido MV,Iglesias-García J

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVES:We compared the clinical profiles and organ manifestations of the commonly encountered immunoglobulin G4-related diseases (IgG4-RDs) on either side of the diaphragm: head and neck (HN) versus pancreatobiliary (PB) in IgG4-RD. METHODS:From the Mayo Clinic, Rochester, database, we identified 53 HN and 88 PB I...

journal_title：Pancreas

authors： Mohapatra S,Sharma A,Chari ST

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:Systemic complications in alcoholic pancreatitis are supposed to be aggravated by inflammatory liver damage. Resident macrophages including hepatic Kupffer cells play a pivotal role in mediating systemic complications in severe necrotizing pancreatitis (SNP). The aim of this study was to evaluate the effects ...

journal_title：Pancreas

authors： Schneider L,Hackert T,Longerich T,Hartwig W,Fritz S,Krych R,Fortunato F,Gebhard MM,Werner J

更新日期：2010-05-01 00:00:00