Differentiation of Pancreatic Masses via Endoscopic Ultrasound Strain Ratio Elastography Using Adjacent Pancreatic Tissue as the Reference.

Abstract:

OBJECTIVES:The aims of this study were to evaluate diagnostic value of endoscopic ultrasound strain ratio elastography in patients with focal pancreatic masses and to determine the cutoff value between the pancreatic malignancies and inflammatory pancreatic masses using reference areas different than those used by other investigators. METHODS:In a prospective single-center study, strain ratio was measured in patients with pancreatic masses. After the diagnosis was established, statistical analysis was used to compare the group with pancreatic malignancies to the one with inflammatory masses. RESULTS:Strain ratio cutoff of 7.59 provided 100% sensitivity, 95% specificity, and 97% overall accuracy for differentiation of patients with pancreatic malignancies from those with inflammatory masses. CONCLUSIONS:Our data show high sensitivity and specificity for the calculated strain ratio. Adjacent normal pancreatic tissue is adequate as a reference area based on the inclusion criteria. Diverse cutoff values and standardization of methods in the studies published so far require further investigations, before the implementation of the method in a routine clinical practice becomes possible.

journal_name

Pancreas

journal_title

Pancreas

authors

Rustemović N,Kalauz M,Grubelić Ravić K,Iveković H,Bilić B,Ostojić Z,Opačić D,Ledinsky I,Majerović M,Višnjić A

doi

10.1097/MPA.0000000000000758

subject

Has Abstract

pub_date

2017-03-01 00:00:00

pages

347-351

issue

3

eissn

0885-3177

issn

1536-4828

journal_volume

46

pub_type

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