Abstract:
OBJECTIVES:The aim of this study was to compare the perioperative clinical characteristics between patients with distal cholangiocarcinoma (DCC) and pancreatic head carcinoma (PHC) with biliary obstruction. METHODS:This study included patients who underwent pancreatoduodenectomy and were diagnosed with DCC (n = 85) or PHC (n = 90) by final pathological examination. Perioperative clinical characteristics were compared for patients with DCC versus PHC with biliary obstruction. RESULTS:Median coronal thickness of the pancreatic neck was significantly greater, whereas the main pancreatic duct diameter was significantly smaller in patients with DCC than patients with PHC. Most patients with DCC (95%) had a soft pancreas, whereas only 29% of patients with PHC had. The incidence rates of overall morbidity, infectious complications, and pancreatic fistula were significantly higher in patients with DCC than those in patients with PHC. Eleven DCC patients (12%) were preoperatively misdiagnosed with PHC. Among them, intraductal ultrasonography of the bile duct was performed in 7 patients, and the presence of PHC was suspected in 3 of these patients because intraductal ultrasonography detected a small intrapancreatic mass. CONCLUSIONS:This study clearly showed different perioperative characteristics between patients with DCC and PHC. It is not uncommon to misdiagnose PHC as DCC. Intraductal ultrasonography may be helpful in differentiating DCC and PHC.
journal_name
Pancreasjournal_title
Pancreasauthors
Yokoyama Y,Ebata T,Igami T,Sugawara G,Mizuno T,Yamaguchi J,Nagino Mdoi
10.1097/MPA.0000000000000942subject
Has Abstractpub_date
2017-11-01 00:00:00pages
1322-1326issue
10eissn
0885-3177issn
1536-4828journal_volume
46pub_type
杂志文章相关文献
PANCREAS文献大全abstract:OBJECTIVES:Inducible nitric oxide synthase (iNOS) activity is increased in experimental acute pancreatitis. The aim of this study was to evaluate treatment with the selective iNOS inhibitors AR-C (AR-C102222AA) and L-NIL (L-N6-(1-iminoethyl)-lysine) in experimental acute pancreatitis. METHODS:Acute pancreatitis was in...
journal_title:Pancreas
pub_type: 杂志文章
doi:
更新日期:2005-01-01 00:00:00
abstract::Chemokines may regulate the process of immune cell infiltration that is often found in pancreatic cancer. In this study, we investigated the secretion of the chemokines [interleukin (IL)-8, monocyte chemoattractant protein (MCP)-1, and RANTES (regulated on activation, normal T cell expressed and secreted)] in human pa...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-200007000-00049
更新日期:2000-07-01 00:00:00
abstract::A 66-year-old patient had been admitted four times for recurrent episodes of acute pancreatitis. At each time, elevated serum calcium levels, between 13.5-14.5 mg/dl, were found. Surgical drainage of necrotic pancreatic tissue had to be done on one occasion. Extensive investigations failed to disclose any conventional...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-198906000-00017
更新日期:1989-01-01 00:00:00
abstract:INTRODUCTION AND AIMS:It has been proposed that distinct tertiary structures of the C-terminus of CCK-8 and CCK-58 result in differences in stimulation of pancreatic amylase secretion. Binding of CCK-8 and CCK-58 to CCK-A and CCK-B receptors and stability to enzymatic digestion were used as independent probes for terti...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-200210000-00021
更新日期:2002-10-01 00:00:00
abstract:OBJECTIVES:Regeneration of the pancreas is initiated by the tubular complexes that consist of a cluster of epithelia surrounded by the mesenchymal cells. They have the potential to become pancreatic lobes, but their growth stops before the complete regeneration of the organ. To elucidate the possibility that we could p...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/01.mpa.0000150110.45017.fc
更新日期:2005-03-01 00:00:00
abstract::In 134 consecutive patients with acute abdominal pain, we evaluated the clinical role of a new rapid test for serum lipase based on latex agglutination. The results were compared with those obtained with a widely used lipase immunoassay as well as with serum amylase and pancreatic isoamylase measurements. Fifty-five h...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-198607000-00005
更新日期:1986-01-01 00:00:00
abstract:OBJECTIVES:Pancreatic duct disruption (PDD) after acute pancreatitis can cause pancreatic collections in the early phase and biliary stenosis (BS) or gastric outlet obstruction (GOO) in the late phase. We aimed to document those late complications after moderate or severe acute pancreatitis. METHODS:Between September ...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/MPA.0000000000001064
更新日期:2018-07-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to determine the accuracy of cytology, carcinoembryonic antigen (CEA), and amylase levels in the preoperative diagnosis of intraductal papillary mucinous neoplasms (IPMNs). METHODS:An international registry was started in 2005 and included patients with clinically suspected IPMNs. ...
journal_title:Pancreas
pub_type: 杂志文章,多中心研究
doi:10.1097/MPA.0000000000000559
更新日期:2016-07-01 00:00:00
abstract::Opioid growth factor (OGF, [Met5]-enkephalin) is an endogenous peptide that regulates the growth of human pancreatic cancer. To evaluate whether human subjects with pancreatic cancer have alterations in plasma levels of OGF, fasting blood samples were obtained from 15 patients with histologically confirmed pancreatic ...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-200008000-00009
更新日期:2000-08-01 00:00:00
abstract:OBJECTIVES:An impaired host immunity might concur in determining the dismal prognosis of patients with pancreatic cancer (PC). Our aim was to ascertain whether the immunophenotype pattern of blood lymphocytes in PC correlates with tumor stage, grade, or survival. METHODS:We studied 115 patients with PC, 44 with chroni...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/01.mpa.0000188305.90290.50
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVE:This study aimed to investigate whether the previously described differentiating islet-like aggregates of human pancreatic adenocarcinoma cells (PANC-1) develop glucose response and exhibit intercellular communication. METHODS:Fura 2-loaded PANC-1 cells in serum-free medium were assayed for changes in cytoso...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/MPA.0b013e3182277e56
更新日期:2012-03-01 00:00:00
abstract:PURPOSE:In this study we investigated the relationship between specific HLA antigens and sporadic pancreatic cancer in Greek population. METHODS:The allele frequencies of serologically and molecular defined class I and II HLA antigens were studied in 60 unrelated patients with pancreatic cancer histologically confirme...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-200407000-00054
更新日期:2004-07-01 00:00:00
abstract:OBJECTIVES:The authors investigated differential expression of cdx2 in intraductal papillary mucinous neoplasm of the pancreas (IPMN) and ductal adenocarcinoma. METHODS:Patients with IPMN (n = 23) and pancreatic ductal adenocarcinoma (n = 30) were studied. Expression of cdx2 mRNA, CDX2 protein, muc2 mRNA, MUC2 apomuci...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/01.mpa.0000153615.55761.00
更新日期:2005-04-01 00:00:00
abstract::Clinical, histopathologic, immunohistochemical, and genetic analyses of 2 osteoclastic giant cell tumors of the pancreas are presented. The neoplasms were composed of osteoclastic giant cells and pleomorphic cells (PCs). The tissue-specific markers gave evidence of mesenchymal nature of the osteoclastic giant cells, a...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/01.mpa.0000202951.10612.fa
更新日期:2006-04-01 00:00:00
abstract:OBJECTIVE:Benign pancreatic hyperenzymemia is characterized by a long-term increase of serum pancreatic enzymes in otherwise healthy subjects. This study was designed to determine (a) whether all pancreatic enzymes are elevated, (b) the extent of each enzyme increase, (c) the relative frequency of the familial form, an...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/MPA.0000000000000138
更新日期:2014-08-01 00:00:00
abstract::A case of relapsing pancreatitis in a young man is presented. Stenosis of the main duct and cystic lesions of the tail of the pancreas were shown by ultrasonography, CT scan, and endoscopic retrograde cholangiopancreatography (ERCP). After a wrong diagnosis of cancer, the pathological examination demonstrated an eosin...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-199001000-00016
更新日期:1990-01-01 00:00:00
abstract::Over 80% of adenocarcinomas of the pancreas originate from duct cells, which are the major source of mucins in the pancreas. Pathological conditions produce changes in the composition and structure of the oligosaccharides of colonic and pancreatic mucins, and it has been suggested that mucins may have a role in the de...
journal_title:Pancreas
pub_type: 杂志文章,评审
doi:10.1097/00006676-199411000-00002
更新日期:1994-11-01 00:00:00
abstract::These studies were undertaken to assess the effects of chronic administration of cerulein plus secretin, every 8 h for 10 days on fluid, protein, and somatostatin-like immunoreactivity (SLI) outputs in rat pancreatic juice. Pancreatic secretion was studied with conscious, cannulated rats, during infusion of precollect...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-198808000-00002
更新日期:1988-01-01 00:00:00
abstract:OBJECTIVE:Opioid therapy for pain in chronic pancreatitis (CP) is associated with tolerance and possibly opioid-induced hyperalgesia. We thus examined opioid use and pain rating in CP patients. METHODS:Medical records of patients with established CP treated at the University of Pittsburgh Medical Center's Digestive Di...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/MPA.0b013e318224056f
更新日期:2012-03-01 00:00:00
abstract::We report a case of severe acute pancreatitis associated with both gastric and abdominal wall infarction. The early skin changes on the anterior abdominal wall could be confused with Grey-Turner's sign. ...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-198808000-00021
更新日期:1988-01-01 00:00:00
abstract:OBJECTIVES:Prior studies have indicated that endogenous or exogenous cholecystokinin (CCK) induces transient acinar cell proliferation at about 24 hours after its stimulation. The aims of the present study were to determine the time point when the administration of the CCK-A-receptor antagonist loxiglumide had its maxi...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/01.mpa.0000202960.63977.d1
更新日期:2006-03-01 00:00:00
abstract:OBJECTIVES:Homocysteine has been implicated in vascular dysfunction and thrombosis, as well as inflammatory conditions. This study was aimed to find out whether chronic pancreatitis (CP) is associated with hyperhomocysteinemia and derangements of transmethylation and transsulfuration pathways. METHODS:We estimated hom...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/mpa.0b013e3181bc0f85
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVES:The immune environment and the potential for neuroendocrine tumors (NETs) to respond to immune checkpoint inhibitors remain largely unexplored. We assessed immune checkpoint marker expression, lymphocytic infiltrate, and associated mutational profiles in a cohort of small intestine and pancreatic NETs. METH...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/MPA.0000000000001150
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVES:Despite a lack of evidence, gabexate mesylate (GM) is routinely used for the treatment of acute pancreatitis (AP) in some countries. The present study examined the effect and cost of GM for AP treatment using the Japanese Diagnosis Procedure Combination database. METHODS:We performed a propensity score anal...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/MPA.0b013e31826495a0
更新日期:2013-03-01 00:00:00
abstract::Examining the actions of L-364,718 on rat pancreatic acini, we found that L-364,718 causes persistent inhibition of cholecystokinin (CCK)-8-stimulated enzyme secretion in acini that were first incubated with L-364,718, washed repeatedly, and then reincubated with CCK-8. This inhibition is maximal after as little as 5 ...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/00006676-199401000-00015
更新日期:1994-01-01 00:00:00
abstract:OBJECTIVES:Pancreatic anastomotic leakage remains a major troublesome complication after pancreaticoduodenectomy. Thus, various technical modifications regarding the pancreatic anastomosis after pancreaticoduodenectomy have been attempted to minimize anastomotic leakage. We have performed duct-to-mucosa pancreaticojeju...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/MPA.0b013e3180676dc2
更新日期:2007-10-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to investigate the biochemical and functional properties of a rat acellular pancreatic bioscaffolds (APBs). METHODS:Fresh pancreata from 10 rats were soaked and perfused through portal veins using Easy-Load Digital Drive peristaltic pumps. The histological structure, extracellular ma...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/MPA.0000000000001123
更新日期:2018-09-01 00:00:00
abstract:OBJECTIVES:The present study describes a simple and cost-effective islet isolation procedure. Using this method, allogeneic islets reverse diabetes in cynomolgus monkeys. METHODS:Pancreatic tissue from 11 cynomolgus monkeys were digested, collected, and purified using a simplified method. Islet quantification, purity,...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/01.mpa.0000437322.44975.13
更新日期:2014-03-01 00:00:00
abstract:OBJECTIVES:The aim was to determine whether serum levels of carbohydrate antigen (CA) 19-9, interleukin 6 (IL-6), and YKL-40 could identify advanced disease and poor prognosis in pancreatic cancer (PC) patients intraoperatively diagnosed with locally advanced or metastatic disease. METHODS:Two hundred ninety patients ...
journal_title:Pancreas
pub_type: 杂志文章
doi:10.1097/MPA.0000000000001466
更新日期:2020-01-01 00:00:00
abstract::The secretin stimulation test is the most sensitive and specific test for pancreatic function. It is usually performed using biologically derived porcine secretin. Several shortages of biologic porcine secretin have occurred in the past few years. The aim of this study was to compare synthetic porcine secretin to biol...
journal_title:Pancreas
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00006676-200010000-00007
更新日期:2000-10-01 00:00:00