Prediction and Management for Relapse of Type 1 Autoimmune Pancreatitis After Initial Steroid Treatment: A Long-Term Follow-up From China.

abstract：:Reports of a so-called "mucin-producing tumor of the pancreas" are increasing worldwide. Although the clinicopathologic features and therapeutic strategies of this tumor have been enthusiastically investigated, there are still many unanswered questions regarding this ailment. In this study, problems in the diagnosis a...

journal_title：Pancreas

authors： Kimura W,Kuroda A,Makuuchi M

更新日期：1998-04-01 00:00:00

abstract：:The nuclear DNA content was assessed by image cytometry on cytologic specimens obtained with fine-needle aspiration biopsy in 96 patients with pancreatic duct carcinoma. Twenty-two of these patients had pancreaticoduodenal resection. According to DNA analysis there were 27 (28%) diploid, 17 (18%) tetraploid, and 52 (5...

journal_title：Pancreas

authors： Linder S,Falkmer U,Hagmar T,Blåsjö M,Sundelin P,von Rosen A

更新日期：1994-11-01 00:00:00

abstract：:Scanning electron microscopy (SEM) and energy dispersive x-ray fluorescence (EDXRF) have been used in this study to investigate the morphology, nature, and arrangement of major, minor, and trace elements in human pancreatic calculi (PC) obtained from patients with alcoholic and tropical pancreatitis. The present study...

journal_title：Pancreas

authors： Pitchumoni CS,Viswanathan KV,Gee Varghese PJ,Banks PA

更新日期：1987-01-01 00:00:00

abstract：OBJECTIVE:Previously reported data suggest that serum leptin concentration changes in some acute and chronic inflammatory diseases. The aim of the present study was to assess serum leptin concentration in patients with chronic pancreatitis. METHODS:Forty-four male patients with chronic pancreatitis and 16 healthy (mal...

journal_title：Pancreas

authors： Adrych K,Smoczynski M,Goyke E,Stelmanska E,Swierczynski J

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:We conducted this study to ascertain whether chronic inflammation secondary to chronic pancreatitis (CP) has any association with myocardial infarction(MI). METHODS:Data were collected from a commercial database (Explorys, Inc, IBM Watson, Ohio). Adults with the diagnosis of "chronic pancreatitis," based on ...

journal_title：Pancreas

authors： Khan D,Abureesh M,Alkhayyat M,Sadiq W,Alshami M,Munir AB,Karam B,Deeb L,Lafferty J

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVES:To investigate the performance of erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) for predicting severe acute pancreatitis (AP). METHODS:Fifty patients with AP were prospectively enrolled. Erythrocyte sedimentation rate and CRP were measured at admission and every 12 hours for 48 hours aft...

journal_title：Pancreas

authors： Pongprasobchai S,Jianjaroonwong V,Charatcharoenwitthaya P,Komoltri C,Tanwandee T,Leelakusolvong S,Pausawasdi N,Srikureja W,Chainuvati S,Prachayakul V,Manatsathit S,Kachintorn U

更新日期：2010-11-01 00:00:00

abstract：:A new technique to obstruct the pancreatic ducts was developed by injecting zein solution into the common bile duct of the rat. Four weeks after the injection, the fate of the endocrine pancreas was investigated by studying (a) pancreatic content of four pancreatic hormones, (b) histology and immunohistochemistry of t...

journal_title：Pancreas

authors： Tomita T,Rhodes J,Falscroft J,Doull V,Kimmel JR,Pollock HG

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVES:We aim to examine the predictive effect of the total number of examined lymph nodes on N stage and survival in pancreatic neuroendocrine neoplasms (pNENs) and to determine the optimal threshold. METHODS:A pNENs data set from 2004 to 2013 was extracted from the Surveillance, Epidemiology, and End Result data...

journal_title：Pancreas

authors： Zhang X,Lu L,Liu P,Cao F,Wei Y,Ma L,Gong P

更新日期：2018-02-01 00:00:00

abstract：:A comparative study of antibacterial activity of pancreatic juice was conducted on six mammalian species. Pancreatic juice collections were conducted as acute (rabbit, guinea pig, rat) and chronic (pig, sheep, cattle) experiments, in the former before and after stimulation [cholecystokinin (CCK) and secretin] and in t...

journal_title：Pancreas

authors： Pierzynowski SG,Sharma P,Sobczyk J,Garwacki S,Barej W,Weström B

更新日期：1993-09-01 00:00:00

abstract：:Several studies have shown that pituitary adenylate cyclase activating polypeptide (PACAP) stimulates at very low concentration insulin release from pancreatic beta cells. In addition, PACAP has been evidenced in pancreatic nervous fibers surrounding the islets, the core of the islet, and the capillaries. The aim of t...

journal_title：Pancreas

authors： Petruzzo P,Cappai A,Spiga S,Picciau S,Serra G,Fattore L,Onali P,Brotzu G

更新日期：2001-07-01 00:00:00

abstract：:Islet amyloid polypeptide (IAPP) has been recently identified as the principal constituent of amyloid deposits in pancreatic islets of patients with type 2 (non-insulin-dependent) diabetes mellitus and causes insulin resistance in some target cells. In addition, glucose-induced insulin secretion is inhibited by IAPP. ...

journal_title：Pancreas

authors： Chuang LM,Wu HP,Jou TS,Tai TY,Lin BJ

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:Green tea polyphenols have been shown to inhibit tumor growth in animal and in vitro studies. We examined the relationship between green tea consumption and the risk of death from pancreatic cancer in a large Japanese cohort. METHODS:At baseline (1988-1990), study participants reported the frequency and amou...

journal_title：Pancreas

authors： Lin Y,Kikuchi S,Tamakoshi A,Yagyu K,Obata Y,Kurosawa M,Inaba Y,Kawamura T,Motohashi Y,Ishibashi T,JACC Study Group.

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to identify differentially expressed proteins in the pancreatic tissue of hepatic alcohol dehydrogenase-deficient deer mice fed ethanol to understand metabolic basis and mechanism of alcoholic chronic pancreatitis. METHODS:Mice were fed liquid diet containing 3.5 g% ethanol daily f...

journal_title：Pancreas

authors： Bhopale KK,Amer SM,Kaphalia L,Soman KV,Wiktorowicz JE,Shakeel Ansari GA,Kaphalia BS

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVES:Previous research has shown that the retinoid 9-cis retinoic acid (RA) promotes apoptosis in pancreatic cancer cells. The vitamin D analog EB1089 does not. Furthermore, cotreatment of cells with 9-cis RA and EB1089 abrogates apoptosis. To explain this, we studied the regulation of proteins involved in apopto...

journal_title：Pancreas

authors： Mouratidis PX,Dalgleish AG,Colston KW

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVES:To evaluate the clinical significance of high-volume modified continuous closed and/or open lavage for the treatment of infected necrotizing pancreatitis. METHODS:From August 1997 to December 2006, 53 patients with infected necrotizing pancreatitis who underwent in situ high-volume (>20 L/d) continuous clos...

journal_title：Pancreas

authors： Dong X,Gao SL,Xie QP,Xu L,Xu YL,Wu YL

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVES:Autoimmune pancreatitis (AIP) responds well to steroid therapy but frequently relapses after discontinuing the steroid. It is difficult to know which cases are most likely to relapse. The aim of this study was to investigate the relation between the rate of decrease in serum IgG4 level after initial steroid ...

journal_title：Pancreas

authors： Shimizu K,Tahara J,Takayama Y,Akao J,Ajihara T,Nagao K,Shiratori K,Tokushige K

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVES:Acute pancreatitis (AP) is a leading cause of hospitalization for a gastrointestinal illness in the United States. We hypothesized that enhanced recovery approaches may lead to earlier time to refeeding in patients with AP. METHODS:We performed a double-blind, randomized controlled trial of patients admitte...

journal_title：Pancreas

authors： Dong E,Chang JI,Verma D,Butler RK,Villarin CK,Kwok KK,Chen W,Wu BU

更新日期：2019-02-01 00:00:00

abstract：:Nicotine is a possible risk factor for chronic pancreatitis and pancreatic cancer. To study the loci where nicotine might exert its effect, we examined interactions between nicotine and rat pancreatic acini. When pancreatic acini were incubated with [3H]nicotine, [3H]nicotine levels in pancreatic acini were increased ...

journal_title：Pancreas

authors： Doi R,Chowdhury P,Nishikawa M,Takaori K,Inoue K,Imamura M,Rayford PL

更新日期：1995-03-01 00:00:00

abstract：OBJECTIVES:Oxidative stress has been implicated in the pathogenesis of chronic pancreatitis (CP) and pancreatic cancer (PC). The study aim was to assess the oxidative stress markers and antioxidant defense system in patients with CP and those with PC. METHODS:Activities of superoxide dismutase 1 (SOD1), catalase (CAT)...

journal_title：Pancreas

authors： Kodydkova J,Vavrova L,Stankova B,Macasek J,Krechler T,Zak A

更新日期：2013-05-01 00:00:00

abstract：:The hedgehog (Hh) family of genes, sonic hedgehog (Shh), Indian hedgehog (Ihh), and desert hedgehog (Dhh) encode signaling molecules that regulate multiple functions during organ development and in adult tissues. Altered hedgehog signaling has been implicated in disturbed organ development as well as in different dege...

journal_title：Pancreas

authors： Kayed H,Kleeff J,Osman T,Keleg S,Büchler MW,Friess H

更新日期：2006-03-01 00:00:00

abstract：:High-quality and well-annotated biorepositories are needed to better understand the pathophysiology and biologic mechanisms of chronic pancreatitis (CP) and its consequences. We report a methodology for the development of a robust standard operating procedure (SOP) for a biorepository based on the experience of the cl...

journal_title：Pancreas

authors： Fisher WE,Cruz-Monserrate Z,McElhany AL,Lesinski GB,Hart PA,Ghosh R,Van Buren G,Fishman DS,Rinaudo JAS,Serrano J,Srivastava S,Mace T,Topazian M,Feng Z,Yadav D,Pandol SJ,Hughes SJ,Liu RY,Lu E,Orr R,Whitcomb DC,Ab

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:Pancreatic ductal adenocarcinoma (PDAC) is the third most common cause of cancer death in the United States. Improved characterized models of PDAC are needed for drug screening. METHODS:We grew 4 established pancreatic cancer cell lines in hanging drop cultures to produce spheroids. We also grew organoids fr...

journal_title：Pancreas

authors： Matsushita Y,Smith B,Delannoy M,Trujillo MA,Chianchiano P,McMillan R,Kamiyama H,Liang H,Thompson ED,Hruban RH,Matsui W,Wood LD,Roberts NJ,Eshleman JR

更新日期：2019-10-01 00:00:00

abstract：:Paraoxonase 1 (PON1) is an antioxidant enzyme that inhibits the oxidative modification of LDL. Since PON1 has been shown to express in pancreatic islets and oxidative stress plays a role in beta-cell dysfunction, we investigated the impact of the PON1 polymorphisms on beta-cell function. This study included 84 healthy...

journal_title：Pancreas

authors： Chiu KC,Chuang LM,Chu A,Lu J,Hu J,Fernando S

更新日期：2004-05-01 00:00:00

abstract：:ATM protein anticipates in the initiation of the DNA repair signal pathway and also mediates cell cycle arrest and repair. ATM deficiency predictably results in radiosensitivity, germ cell degeneration, chromosomal instability, immunodeficiency, and an extreme predisposition to tumors. Moreover, studies found that ATM...

journal_title：Pancreas

authors： Yu G,Zhu MH,Zhu Z,Ni CR,Zheng JM,Li FM

更新日期：2004-05-01 00:00:00

abstract：:Opioid growth factor (OGF, [Met5]-enkephalin) is an endogenous peptide that regulates the growth of human pancreatic cancer. To evaluate whether human subjects with pancreatic cancer have alterations in plasma levels of OGF, fasting blood samples were obtained from 15 patients with histologically confirmed pancreatic ...

journal_title：Pancreas

authors： Smith JP,Conter RL,Demers TM,McLaughlin PJ,Zagon IS

更新日期：2000-08-01 00:00:00

abstract：:This study compared diet, type of alcoholism, and smoking in three groups of alcoholic men, with chronic pancreatitis (n = 56), with histological cirrhosis (n = 50), and without pancreatitis or cirrhosis (controls; n = 50) by a multidimensional analysis. Only patients in whom the first symptom of pancreatitis or cirrh...

journal_title：Pancreas

authors： Lévy P,Mathurin P,Roqueplo A,Rueff B,Bernades P

更新日期：1995-04-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to investigate whether 6 candidate serum miRNAs and their interactions with serum folate level were associated with the risk for pancreatic cancer (PC). METHOD:A hospital-based case-control study including 74 incident PC cases and 74 controls was conducted. Serum folate and miRNAs ...

journal_title：Pancreas

authors： Tian Y,Xue Y,Ruan G,Cheng K,Tian J,Qiu Q,Xiao M,Li H,Yang H,Wang L

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVES:The purpose of the present study was to compare the development of murine embryonic pancreas in vitro and in vivo. METHODS:Murine embryonic pancreas at 12.5 days of gestation was dissected and cultured at the air-medium interface. At 1, 3, and 7 days of culture, the characteristics of cultured murine pancre...

journal_title：Pancreas

authors： Ma F,Haumaitre C,Chen F,Han Z

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVES:Interleukin-36 (IL-36) is a recently described proinflammatory cytokine, characterized by the induction of inflammatory mediators. In the present study, we investigated the biological activity and the signal transduction of IL-36α in human pancreatic myofibroblasts. METHODS:The mRNA and protein expression o...

journal_title：Pancreas

authors： Nishida A,Inatomi O,Fujimoto T,Imaeda H,Tani M,Andoh A

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVE:Ethnic disparities in pancreatic cancer (PanCan) incidence exist, but little is known about incidence trends in heterogeneous Asian Americans. We examined PanCan incidence and temporal patterns among detailed ethnic populations, including Asian American subgroups. METHODS:A total of 71,099 invasive exocrine ...

journal_title：Pancreas

authors： Liu L,Zhang J,Deapen D,Stern MC,Sipin A,Pandol SJ,Setiawan VW

更新日期：2019-08-01 00:00:00