Preliminary results of the use of intraperitoneal carbon-adsorbed mitomycin C in intra-abdominal malignancy.

abstract：BACKGROUND:Use of antibiotics could alter human microbiota composition and decrease bacterial diversity. Such microbial dysbiosis may have implications in hepatocarcinogenesis; however, the association between antibiotic use and liver cancer risk has been minimally examined in humans. METHODS:We performed a nested cas...

journal_title：British journal of cancer

authors： Yang B,Hagberg KW,Chen J,Sahasrabuddhe VV,Graubard BI,Jick S,McGlynn KA

更新日期：2016-06-28 00:00:00

abstract：:The oncogenicity of Duck hepatitis B virus (DHBV) is unclear since hepatocellular carcinomas (HCCs) have been reported only in domestic ducks in Qidong, an area of China where hepatitis B virus (HBV) and aflatoxin B1 (AFB1) are risk factors for liver cancer in man. In order to better define the association between DHB...

journal_title：British journal of cancer

authors： Cova L,Mehrotra R,Wild CP,Chutimataewin S,Cao SF,Duflot A,Prave M,Yu SZ,Montesano R,Trepo C

更新日期：1994-01-01 00:00:00

abstract：:E-cadherin function is thought to be impaired in epithelial cancer. To investigate the alterations in E-cadherin associated with cytoplasmic molecules including alpha-catenin, beta-catenin, gamma-catenin, p120CAS, and IQGAP1 in various endometrial cancers with different degree of differentiation, we examined the local...

journal_title：British journal of cancer

authors： Miyamoto S,Baba H,Kuroda S,Kaibuchi K,Fukuda T,Maehara Y,Saito T

更新日期：2000-11-01 00:00:00

abstract：:Small-cell lung cancers (SCLCs) initially respond to chemotherapy, but are often resistant at recurrence. The non-steroidal anti-inflammatory drug indomethacin is an inhibitor of multidrug resistance protein 1 (MRP1) function. The doxorubicin-resistant MRP1-overexpressing human SCLC cell line GLC(4)-Adr was highly sen...

journal_title：British journal of cancer

authors： de Groot DJ,van der Deen M,Le TK,Regeling A,de Jong S,de Vries EG

更新日期：2007-10-22 00:00:00

abstract：BACKGROUND:The diagnosis of neuroendocrine neoplasms (NENs) is often delayed. This first UK population-based epidemiological study of NENs compares outcomes with non-NENs to identify any inequalities. METHODS:Age-standardised incidence rate (ASR), 1-year overall survival, hazard ratios and standardised mortality rates...

journal_title：British journal of cancer

authors： Genus TSE,Bouvier C,Wong KF,Srirajaskanthan R,Rous BA,Talbot DC,Valle JW,Khan M,Pearce N,Elshafie M,Reed NS,Morgan E,Deas A,White C,Huws D,Ramage J

更新日期：2019-11-01 00:00:00

abstract：:Forty-two patients with clinical stage IIIA or IIIB breast cancer were treated with neoadjuvant chemotherapy followed by mastectomy and radiotherapy. The median follow-up was 32 months (range 10-72 months) and the median time to progression was 17 months (range 10-30 months). A multivariate analysis showed that a long...

journal_title：British journal of cancer

authors： Honkoop AH,van Diest PJ,de Jong JS,Linn SC,Giaccone G,Hoekman K,Wagstaff J,Pinedo HM

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:Pancreaticoduodenectomy remains a major undertaking. A preoperative blood test, which could confidently predict the benefits of surgery would improve the selection of pancreatic cancer patients for surgery. This study aimed to identify protein biomarkers prognostic for long-term survival and to validate them...

journal_title：British journal of cancer

authors： Xue A,Chang JW,Chung L,Samra J,Hugh T,Gill A,Butturini G,Baxter RC,Smith RC

更新日期：2012-11-20 00:00:00

abstract：:The fluorometric microculture cytotoxicity assay (FMCA) was employed for analysing the effect of different chemotherapeutic drug combinations and their single constituents in 44 cases of acute myelocytic leukaemia (AML). A large heterogeneity with respect to cell kill was observed for all combinations tested, the inte...

journal_title：British journal of cancer

authors： Larsson R,Fridborg H,Kristensen J,Sundström C,Nygren P

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND:We used bleomycin, etoposide, cisplatin (BEP), the most effective regimen in the treatment of germ cell tumours (GCTs) and increased dose-density by using pegfilgrastim to shorten cycle length. Our aim was to assess safety and tolerability. METHODS:Sixteen male patients with intermediate or poor prognosis m...

journal_title：British journal of cancer

authors： Rimmer Y,Chester J,Joffe J,Stark D,Shamash J,Powles T,White J,Wason J,Parashar D,Armstrong G,Mazhar D,Williams MV

更新日期：2011-09-06 00:00:00

abstract：:The association between soya foods and breast cancer risk was investigated in a prospective study of 34759 women in Hiroshima and Nagasaki, Japan. Women completed dietary questionnaires in 1969-1970 and/or in 1979-1981 and were followed for incident breast cancer until 1993. The analysis involved 427 cases of primary ...

journal_title：British journal of cancer

authors： Key TJ,Sharp GB,Appleby PN,Beral V,Goodman MT,Soda M,Mabuchi K

更新日期：1999-12-01 00:00:00

abstract：:Mice transplanted with NC carcinoma were treated with the thromboxane synthetase inhibitor dazmegrel (UK38485) or with nafazatrom (BAY G 6575), a compound that is reported to increase prostacyclin formation. Some experiments included the cytotoxic drugs methotrexate and melphalan. The tumours were excised under anaest...

journal_title：British journal of cancer

authors： Stamford IF,Melhuish PB,Carroll MA,Corrigan CJ,Patel S,Bennett A

更新日期：1986-08-01 00:00:00

abstract：BACKGROUND:To describe the prescription patterns of analgesics during the last 3 months of life in lung cancer and to determine the associated factors. METHODS:Data on lung cancer patients (N=10,202) who died during 2000-2008 were extracted from the General Practice Research Database (GPRD). This database records pres...

journal_title：British journal of cancer

authors： Gao W,Gulliford M,Higginson IJ

更新日期：2011-05-24 00:00:00

abstract：:The development of an altered stromal microenvironment is a common feature of many tumours including squamous cell carcinoma (SCC), and there is increasing evidence that these changes in the stroma, which include increased expression of proteases and cytokines, may actually promote tumour progression. A common finding...

journal_title：British journal of cancer

authors： Lewis MP,Lygoe KA,Nystrom ML,Anderson WP,Speight PM,Marshall JF,Thomas GJ

更新日期：2004-02-23 00:00:00

abstract：BACKGROUND:The role of further hormone therapy in castration-resistant prostate cancer (CRPC) remains unclear. We performed a multi-centre randomised phase III study comparing the use of Dexamethasone, Aspirin, and immediate addition of Diethylstilbestrol (DAiS) vs Dexamethasone, Aspirin, and deferred (until disease pr...

journal_title：British journal of cancer

authors： Shamash J,Powles T,Sarker SJ,Protheroe A,Mithal N,Mills R,Beard R,Wilson P,Tranter N,O'Brien N,McFaul S,Oliver T

更新日期：2011-02-15 00:00:00

abstract：:We evaluated the interaction between hepatitis C virus (HCV) and cigarette smoking on death from hepatocellular cancer in The Japan Collaborative Cohort Study. The odds ratio of death from HCC for smoking was 9.60 (1.50-61.35) and 1.71(0.58-5.08) among anti-HCV positive and negative individuals, respectively. ...

journal_title：British journal of cancer

authors： Fujita Y,Shibata A,Ogimoto I,Kurozawa Y,Nose T,Yoshimura T,Suzuki H,Iwai N,Sakata R,Ichikawa S,Tamakoshi A

更新日期：2006-03-13 00:00:00

abstract：:The patterns of early and late relapses (those occurring later than 3 years after diagnosis) in 432 patients achieving complete remission after treatment for stage I and II Hodgkin's disease at the Royal Marsden Hospital between 1964 and 1983 were studied to identify factors predicting for late relapse. The incidence ...

journal_title：British journal of cancer

authors： Duchesne G,Crow J,Ashley S,Brada M,Horwich A

更新日期：1989-08-01 00:00:00

abstract：:The nonsteroidal anti-inflammatory drug aspirin and the spice curcumin retard adenoma formation when administered long-term to Apc(Min/+) mice, a model of human familial adenomatous polyposis coli. Both agents interfere with cyclooxygenase activity. When aspirin is administered to Apc(Min/+) mice only postweaning, but...

journal_title：British journal of cancer

authors： Perkins S,Clarke AR,Steward W,Gescher A

更新日期：2003-05-06 00:00:00

abstract：:Photodynamic therapy (PDT) using Photofrin was used in combination with a hypoxic toxin (mitomycin C, MMC) to treat four patients with recurrent skin metastasis of a mammary carcinoma. In preclinical experiments an additive effect was found for the combination of MMC and PDT for treating subcutaneous RIF1 tumours in m...

journal_title：British journal of cancer

authors： Baas P,van Geel IP,Oppelaar H,Meyer M,Beynen JH,van Zandwijk N,Stewart FA

更新日期：1996-04-01 00:00:00

abstract：:Over the period 1966-1995, based on 11,662 patients, the incidence of squamous cell carcinoma of the skin increased three to four times in Norway mainly as a result of an increased number of localized tumours. In men, cancer of the auricle was the second most common site; in women the incidence was low. ...

journal_title：British journal of cancer

authors： Iversen T,Tretli S

更新日期：1999-10-01 00:00:00

abstract：:Iodine-123-labelled tumour associated monoclonal antibody HMFG2 was administered intralymphatically at a time that cannulation of pedal lymphatic vessels was performed for standard lymphangiography in 6 patients with cervical cancer. Gamma camera images were taken at 2 h and 24 h after injection of antibody and at a s...

journal_title：British journal of cancer

authors： Epenetos AA

更新日期：1985-06-01 00:00:00

abstract：:The relationship between aspirin use and colorectal cancer risk was examined by a case-control study in Italy. Regular aspirin use was reported by only 47 (3.5%) cases and 77 (4.1%) control subjects, giving a multivariate odds ratio (OR) of 0.7 (95% CI 0.5-1.0) after allowance for education, physical exercise and sele...

journal_title：British journal of cancer

authors： La Vecchia C,Negri E,Franceschi S,Conti E,Montella M,Giacosa A,Falcini A,Decarli A

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Osteosarcoma (OS) is the most common primary bone tumour in children and adolescents. Patients who respond poorly to chemotherapy have a higher risk of metastatic disease and 5-year survival rates of only 10-20%. Therefore, identifying molecular targets that are specific for OS, or more specifically, metasta...

journal_title：British journal of cancer

authors： Endo-Munoz L,Cumming A,Sommerville S,Dickinson I,Saunders NA

更新日期：2010-06-29 00:00:00

abstract：:Cellular senescence is an established tumour-suppressive mechanism that prevents the proliferation of premalignant cells. However, several lines of evidence show that senescent cells, which often persist in vivo, can also promote tumour progression in addition to other age-related pathologies via the senescence-associ...

journal_title：British journal of cancer

authors： Lecot P,Alimirah F,Desprez PY,Campisi J,Wiley C

更新日期：2016-05-24 00:00:00

abstract：:Expression of the calcium-dependent cell-cell adhesion molecule E-cadherin has been examined in 187 primary breast carcinomas using an immunohistochemical technique. The pattern and extent of reactivity has been correlated with clinicopathological data including tumour type, grade and lymph node status and with other ...

journal_title：British journal of cancer

authors： Jones JL,Royall JE,Walker RA

更新日期：1996-10-01 00:00:00

abstract：:We have analysed DNA extracted from the serum and peritoneal fluid of 20 ovarian cancer patients for the presence of tumour-specific genetic alterations. The 20 patients included six with stage Ia disease. Using six polymorphic microsatellite loci we were able to detect novel alleles or loss of heterozygosity in 17/20...

journal_title：British journal of cancer

authors： Hickey KP,Boyle KP,Jepps HM,Andrew AC,Buxton EJ,Burns PA

更新日期：1999-08-01 00:00:00

abstract：:Pancreatic tumours are scirrhous, avascular tumours, suggesting that they may produce angiogenesis inhibitors that suppress the growth of the vasculature to the tumour and metastases. We have sought evidence for the angiogenesis inhibitor, endostatin, in normal and cancerous pancreatic tissue. Using Western blotting, ...

journal_title：British journal of cancer

authors： Brammer RD,Bramhall SR,Eggo MC

更新日期：2005-01-17 00:00:00

abstract：:Male and female Swiss strain mice were put on a 0.03% thioacetamide diet at the age of 2 months. Control mice were kept on a stock diet. Control and treated mice were killed at the ages of 6, 9, 13 and 17 months. Progressive morphological, histological and biochemical alterations in the liver and tumour tissue of the ...

journal_title：British journal of cancer

authors： Gothoskar SV,Talwalkar GV,Bhide SV

更新日期：1970-09-01 00:00:00

abstract：:Darbepoetin alfa is a novel erythropoiesis stimulating protein (NESP), which stimulates erythropoiesis by the same mechanism as recombinant human erythropoietin (rHuEPO). NESP has been shown to be safe and efficacious in patients with chronic renal failure. NESP is biochemically distinct from rHuEPO, due to its increa...

journal_title：British journal of cancer

authors： Glaspy J,Jadeja JS,Justice G,Kessler J,Richards D,Schwartzberg L,Rigas J,Kuter D,Harmon D,Prow D,Demetri G,Gordon D,Arseneau J,Saven A,Hynes H,Boccia R,O'Byrne J,Colowick AB

更新日期：2001-04-01 00:00:00

abstract：:We assayed methyl-p-hydroxyphenyllactate esterase (MeHPLAase) activity in 63 cases of primary laryngeal squamous cell carcinoma. MeHPLAase activity did not show any correlation with oestrogen, progesterone and epidermal growth factor (EGF) receptor levels. No significant relationship was found between MeHPLAase activi...

journal_title：British journal of cancer

authors： Maurizi M,Ferrandina G,Almadori G,Scambia G,Cadoni G,D'Agostino G,Serra FG,Piantelli M,Mancuso S,Ranelletti FO

更新日期：1998-04-01 00:00:00

abstract：:A number of growth factors have been implicated in the control of the proliferation of breast cancer cells and some have been reported to mediate the proliferative effects of oestradiol. MCF-7 cells were treated with growth factors in the presence and absence of oestradiol. Oestradiol increased the response of cells t...

journal_title：British journal of cancer

authors： Stewart AJ,Westley BR,May FE

更新日期：1992-10-01 00:00:00