The performance of DSM-III-R major depression criteria in the diagnosis of bipolar mixed states.

Abstract:

:Two hundred thirty-seven (237) manic patients diagnosed by DSM-III-R criteria as either purely manic (204) or mixed bipolar (33) were reviewed for analysis of the diagnostic performance of the DSM-III-R criteria required to diagnose the mixed bipolar state. We calculated the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and diagnostic efficiency of each of the 9 DSM-III-R criteria for major depression in this cohort. As predicted, four of the major depression criteria had low diagnostic utility, with PPV's less than 0.3. Those items were: weight change; sleep disturbance; psychomotor change; and diminished ability to think or concentrate or indecisiveness. Four symptoms: anhedonia, fatigue, feelings of worthlessness or guilt, and recurrent thoughts of death or suicidal ideation had acceptable utility for the diagnosis of mixed states.

journal_name

J Affect Disord

authors

Cassidy F,Murry E,Forest K,Carroll BJ

doi

10.1016/s0165-0327(97)00084-0

subject

Has Abstract

pub_date

1997-10-01 00:00:00

pages

79-81

issue

1

eissn

0165-0327

issn

1573-2517

pii

S0165-0327(97)00084-0

journal_volume

46

pub_type

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