Abstract：
:Severe depression is characterized by anorexia and weight loss, symptoms that could endanger the patient's nutritional state. In order to investigate the nutritional state of depressed patients we determined the following in 113 healthy controls and depressed inpatients: (1) anthropometric variables such as body weight, ideal body weight (IBW), percentage of IBW, mean arm circumference, triceps skinfold thickness and arm muscle circumference, and (2) biochemical parameters such as albumin (Alb), prealbumin (Prealb), and transferrin (Tf). We were unable to detect any differences in the anthropometric parameters between healthy controls, minor and major depressed patients. Depressed patients exhibited significantly lower Alb and Tf levels than healthy controls. The drop in both plasma proteins was highly sensitive (72%) and specific (92%) for melancholia. These results may point towards the existence of a disorder in protein homeostasis or protein malnutrition without a marasmic component.
journal_name
J Affect Disordjournal_title
Journal of affective disordersauthors
Maes M,Vandewoude M,Scharpé S,De Clercq L,Stevens W,Lepoutre L,Schotte Cdoi
10.1016/0165-0327(91)90032-nsubject
Has Abstractpub_date
1991-09-01 00:00:00pages
25-33issue
1eissn
0165-0327issn
1573-2517pii
0165-0327(91)90032-Njournal_volume
23pub_type
杂志文章abstract：BACKGROUND:The Patient Health Questionnaire (PHQ-9) and Hospital Anxiety and Depression Scale (HADS) are commonly used measures in clinical practice and research. It is important that such scales measure the trait they purport to measure and that the impact of other measurement artefacts is minimal. Differential item f...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2012.11.015
更新日期：2013-05-01 00:00:00
abstract：:We examined the relationship between the DST and 4 definitions of endogenous depression: DSM-III, Feinberg and Carroll, Newcastle and RDC. Endogenous patients had a significantly higher rate of nonsuppression than nonendogenous patients according to the DSM-III and Newcastle definitions but not according to the RDC an...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/0165-0327(85)90070-9
更新日期：1985-01-01 00:00:00
abstract：BACKGROUND:Tobacco use has been associated with externalized personality traits. Our aim was to evaluate the association of smoking with emotional and affective temperaments in a large sample. METHODS:In this cross-sectional web-based survey, volunteers completed the Combined Emotional and Affective Temperament Scale ...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2010.04.016
更新日期：2010-12-01 00:00:00
abstract：BACKGROUND:Magnetic resonance imaging (MRI) studies have yielded inconsistent findings with regard to subcortical volumetric abnormalities in patients with bipolar I disorder. Duration of illness and long term medication intake could have confounded the findings. METHOD:Volumes of nine subcortical structures were comp...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2017.06.051
更新日期：2017-11-01 00:00:00
abstract：BACKGROUND:Throughout the past decades, several methods have been developed to achieve therapeutic lithium blood levels as quick and safe as possible. The present study will systematically review the methods developed and studied for lithium dose estimation or level prediction at the initiation of therapy. METHODS:A s...
journal_title：Journal of affective disorders
pub_type： 杂志文章,评审
doi：10.1016/j.jad.2012.08.013
更新日期：2013-03-20 00:00:00
abstract：:Twenty affective disorder patients (16 bipolar and 4 unipolar) and 24 normal controls received scans with positron emission tomography (PET) using [18F]2-deoxyglucose (FDG) as a tracer. Subjects received a series of brief electrical stimuli to their right arms during FDG uptake. Patients with bipolar affective illness...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/0165-0327(86)90036-4
更新日期：1986-03-01 00:00:00
abstract：BACKGROUND:Two recent studies conducted in the US and in France found an unexpectedly high prevalence of a positive screen for bipolar disorder (BD) in primary care (PC). There are few studies of the prevalence of BD in PC and no information exists on the epidemiology of BD in Brazilian PC services. This study investig...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2012.05.040
更新日期：2012-12-20 00:00:00
abstract：BACKGROUND:Methylarginines are endogenous nitric oxide synthase inhibitors that have been implicated in depression. This study measured serum concentrations of l-arginine, asymmetric (ADMA) and symmetric (SDMA) dimethylarginine in a representative sample of older community-dwelling adults and determined their associati...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2013.06.033
更新日期：2013-11-01 00:00:00
abstract：BACKGROUND:Our recent work indicated that low-expression of the anti-apoptotic protein B-cell/lymphoma 2 (Bcl-2) mRNA was observed among untreated major depressive disorder (MDD) patients, and the subsequent altered level of Bcl-2 was found to be close to the antidepressant treatment outcome. The primary aim of this pr...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2013.11.010
更新日期：2014-02-01 00:00:00
abstract：BACKGROUND:Little is known about the influence of psychiatric factors on the etiology of placental abruption (PA), an obstetrical condition that complicates 1-2% of pregnancies. We examined the risk of PA in relation to maternal psychiatric symptoms during pregnancy. METHODS:This case-control study included 373 PA cas...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2010.07.024
更新日期：2011-04-01 00:00:00
abstract：:The advisability of continuing breastfeeding is an important issue for women with postpartum depression or psychosis. A review of the literature on psychotropic drugs in breast milk is presented. All of the major classes of psychotropic drugs (antidepressants, antipsychotics, antianxiety agents, lithium, hypnotics) ha...
journal_title：Journal of affective disorders
pub_type： 杂志文章,评审
doi：10.1016/0165-0327(90)90092-m
更新日期：1990-07-01 00:00:00
abstract：BACKGROUND:Anxiety disorders are a category of mental disorders characterized by feelings of anxiety and fear, which include generalized anxiety disorder (GAD). Obsessive-Compulsive Disorder (OCD) used to be categorized as anxiety disorder in DSM-IV. However OCD was no longer included in anxiety disorders and came into...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2015.07.023
更新日期：2015-11-01 00:00:00
abstract：BACKGROUND:Women who have suffered from one episode of postpartum-onset major depression (PPMD) experience increased risk for recurrence in the year following another birth. METHODS:Non-depressed women (N=51) who had at least one past episode of PPMD were recruited during pregnancy. After birth, subjects were assessed...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/S0165-0327(02)00305-1
更新日期：2004-03-01 00:00:00
abstract：BACKGROUND:Various studies showed that personality traits and resilience might have impacts on depressive symptoms, separately. However, the relationships among personality traits, resilience and depressive symptoms are still undefined. Thus, this study tried to explore the potential effect of resilience on the associa...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2019.11.102
更新日期：2020-03-15 00:00:00
abstract：BACKGROUND:Social anxiety disorder is fairly prevalent among alcohol abusing/dependent subjects. The objective of the present study was to investigate: (a) the incidence of social anxiety symptoms in inpatient alcoholics, (b) the effect of alcohol detoxification on these symptoms, and (c) whether a combined psychothera...
journal_title：Journal of affective disorders
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0165-0327(02)00094-0
更新日期：2003-09-01 00:00:00
abstract：BACKGROUND:Understanding the neurobiology of depression and the mechanism of action of therapeutic measures is currently a research priority. We have shown that the expression of the synaptic protein Homer1a correlates with depression-like behavior and its induction is a common mechanism of action of different antidepr...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2020.10.040
更新日期：2021-01-15 00:00:00
abstract：BACKGROUND:Post-stroke depression (PSD) is a serious and common complication of stroke. In this prospective study on the relationship between clinical PSD and physical recovery, we focused on (1) distinguishing between depression and apathy, (2) issues in assessment of PSD, and (3) timing of assessment. METHODS:Japane...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2015.01.020
更新日期：2015-05-01 00:00:00
abstract：BACKGROUND:The purpose of this study was to search for correlations of scores on the visual analog scales (VAS) taken during the third week postpartum with scores on the Edinburgh Postnatal Depression Scale (EPDS) taken on approximately day 28 postpartum. METHODS:Thirty-four women filled out six visual analog scales o...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2005.01.001
更新日期：2005-06-01 00:00:00
abstract：BACKGROUND:The Edinburgh Postnatal Depression Scale (EPDS) was developed as a uni-dimensional measure of depression, however there is evidence that it also measures anxiety. This study examined the factor structure of the EPDS and validity of the identified subscales. METHOD:309 women with infants aged up to 12 months...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2009.02.004
更新日期：2009-11-01 00:00:00
abstract：BACKGROUND:Pre-treatment sleep disturbance has been shown to predict antidepressant treatment outcomes. How changes in sleep disturbance during acute treatment affect longitudinal outcomes, or whether continuation-phase treatment further improves sleep disturbance, is unclear. METHODS:We assessed sleep disturbance rep...
journal_title：Journal of affective disorders
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jad.2019.10.033
更新日期：2020-02-01 00:00:00
abstract：:Computed axial brain tomography was studied in 25 patients with panic disorder. Patients had normal ventricular-brain ratio (VBR) compared to published norms. There was a significant association between VBR and duration of benzodiazepine use. ...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/0165-0327(87)90011-5
更新日期：1987-03-01 00:00:00
abstract：BACKGROUND:Sleep spindles are believed to mediate several sleep-related functions including maintaining disconnection from the external environment during sleep, cortical development, and sleep-dependent memory consolidation. Prior studies that have examined sleep spindles in major depressive disorder (MDD) have not de...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2012.06.016
更新日期：2013-03-20 00:00:00
abstract：BACKGROUND:We studied emotional information processing in youth with pediatric bipolar disorder (pBD) using the late positive potential (LPP), assessing automatic allocation of attentional resources to emotionally salient stimuli, and the occipital P1, assessing early sensory processing. METHODS:Participants were 20 y...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2019.04.076
更新日期：2019-06-15 00:00:00
abstract：BACKGROUND:This study aimed to test the validity of using the Hypomania Checklist-16 [HCL-16] to measure hypomania in a British adolescent community sample. Limited research is available concerning the characterization of hypomania among community adolescent samples, particularly in the UK, despite its potential import...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2016.08.033
更新日期：2017-01-01 00:00:00
abstract：:Kraepelin had a modern vision of affective illness. He hypothesized that affective recurrences arose from enduring dispositions of depressive, cyclothymic, irritable, or 'manic' types. These dispositions appeared as 'temperaments' in English translations of his work. In the extreme, such temperamental gloominess or mo...
journal_title：Journal of affective disorders
pub_type： 杂志文章,评审
doi：10.1016/s0165-0327(00)00347-5
更新日期：2001-01-01 00:00:00
abstract：BACKGROUND:Neurokinin 1 receptors (NK-1R) have been involved in several psychiatric disorders including major depression, but less is known for bipolar disorder (BD). METHOD:We compared NK-1R expression and Substance P (SP) ability to induce NF-κB activation in monocytes from BD patients and healthy donors (HD), also ...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2015.03.013
更新日期：2015-06-01 00:00:00
abstract：INTRODUCTION:Both rumination, a pattern of repetitive, self-focused thought in response to distress, and deficits in executive functions (EFs), a set of cognitive abilities that facilitate higher-order thinking, have transdiagnostic associations with psychopathology. Although empirical studies suggest associations betw...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2019.06.026
更新日期：2019-09-01 00:00:00
abstract：BACKGROUND:The anterior cingulate cortex (ACC) is a key region for the pathophysiology and treatment of depression. However, it remains unclear whether and how the morphology of the ACC is altered in subjects with mood disorders. METHOD:A post mortem morphometric study of the supragenual ACC (Brodmann area 24b) in sev...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2011.03.042
更新日期：2011-09-01 00:00:00
abstract：BACKGROUND:Recent studies on the pathophysiology of major depression (MD) indicate that degenerative and inflammatory processes may play a role. This finding is supported by magnetic resonance imaging (MRI)-based meta-analysis that show volume reductions in circumscribed areas of the brain in patients with MD. Using op...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2017.11.077
更新日期：2018-02-01 00:00:00
abstract：OBJECTIVE:Histories of childhood trauma (CT) are risk factors for affect dysregulation and poor clinical outcomes in women with bipolar disorder (BD). While much is known about the link between BD and CT in adult patients, there is limited data on this research topic in pediatric BD (PBD). The present study aims to inv...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2018.12.007
更新日期：2019-03-15 00:00:00
