Abstract:
BACKGROUND:Individuals with bipolar disorder lead a sedentary lifestyle associated with worse course of illness and recurrence of symptoms. Identifying potentially modifiable predictors of exercise frequency could lead to interventions with powerful consequences on the course of illness and overall health. METHODS:The present study examines baseline reports of exercise frequency of bipolar patients in a multi-site comparative effectiveness study of a second generation antipsychotic (quetiapine) versus a classic mood stabilizer (lithium). Demographics, quality of life, functioning, and mood symptoms were assessed. RESULTS:Approximately 40% of participants reported not exercising regularly (at least once per week). Less frequent weekly exercise was associated with higher BMI, more time depressed, more depressive symptoms, and lower quality of life and functioning. In contrast, more frequent exercise was associated with experiencing more mania in the past year and more current manic symptoms. LIMITATIONS:Exercise frequency was measured by self-report and details of the exercise were not collected. Analyses rely on baseline data, allowing only for association analyses. Directionality and predictive validity cannot be determined. Data were collected in the context of a clinical trial and thus, it is possible that the generalizability of the findings could be limited. CONCLUSION:There appears to be a mood-specific relationship between exercise frequency and polarity such that depression is associated with less exercise and mania with more exercise in individuals with bipolar disorder. This suggests that increasing or decreasing exercise could be a targeted intervention for patients with depressive or mood elevation symptoms, respectively.
journal_name
J Affect Disordjournal_title
Journal of affective disordersauthors
Sylvia LG,Friedman ES,Kocsis JH,Bernstein EE,Brody BD,Kinrys G,Kemp DE,Shelton RC,McElroy SL,Bobo WV,Kamali M,McInnis MG,Tohen M,Bowden CL,Ketter TA,Deckersbach T,Calabrese JR,Thase ME,Reilly-Harrington NA,Singh V,doi
10.1016/j.jad.2013.07.031subject
Has Abstractpub_date
2013-11-01 00:00:00pages
722-727issue
2eissn
0165-0327issn
1573-2517pii
S0165-0327(13)00602-2journal_volume
151pub_type
杂志文章,随机对照试验abstract:BACKGROUND:The aim was to examine the prevalence and consequences of co-occurring insomnia and hypersomnia symptoms in depressed adults drawn from a representative sample of the U.S. population. METHOD:Data from 687 National Comorbidity Survey Replication (NCS-R) respondents meeting criteria for a major depressive epi...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2014.05.060
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:More than 50% of individuals with bipolar disorder (BD) do not reach full psychosocial functioning, even during periods of euthymia. It has been suggested that history of psychotic symptoms is one of the factors which are associated with a worse functional outcome. The objective was to compare psychosocial f...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2017.12.094
更新日期:2018-03-15 00:00:00
abstract:BACKGROUND:There is evidence that both a past history of psychiatric illness and insecure attachment put women at risk for mood disturbances in the postpartum period. The aim of this study was to ascertain whether maternal insecure attachment is a risk factor for mood symptoms in the immediate postpartum period indepen...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2017.01.039
更新日期:2017-04-01 00:00:00
abstract:BACKGROUND:Post-traumatic stress disorder (PTSD) in Veterans is associated with increased sexual risk behaviors, but the nature of this association is not well understood. Typical PTSD measurement deriving a summary estimate of symptom severity over a period of time precludes inferences about symptom variability, and w...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2015.10.039
更新日期:2016-01-15 00:00:00
abstract:BACKGROUND:Depressed mood, anhedonia, psychomotor retardation and alterations of circadian rhythm are core features of the depressive syndrome. Its neural correlates can be located within a frontal-striatal-tegmental neural network, commonly referred to as the reward circuit. It is the aim of this article to review lit...
journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/j.jad.2015.06.041
更新日期:2015-11-15 00:00:00
abstract::472 bipolar patients were followed up retrospectively over 17 years. The patients that died were compared with the general population and a control group. The former comparison showed greater mortality from suicide, cardiovascular and respiratory causes in the index population and the latter, that the deceased were mo...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(94)90112-0
更新日期:1994-06-01 00:00:00
abstract:BACKGROUND:Lithium is the lightest metal and the only mood stabilizer that has been used for over half a century for the treatment of bipolar disorder (BD). As a small ion, lithium is omnipresent, and consequently, its molecular mechanisms and targets are widespread. Currently, lithium is a crucial pharmacotherapy for ...
journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/j.jad.2017.12.026
更新日期:2018-06-01 00:00:00
abstract::The lifetime prevalence of mood disorders in women is approximately twice that of men. The underlying causality of this gender difference is not yet understood. There is increasing scientific attention to the modulation of the neuroendocrine system by fluctuating gonadal hormones. This review attempts to summarize our...
journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/s0165-0327(02)00432-9
更新日期:2003-03-01 00:00:00
abstract:BACKGROUND:Evaluations of clinical depression are traditionally based on verbal information. Nonverbal expressive behavior, however, being associated with a person's reflexive responses, may reveal negative emotional or social processes that are not under complete control of the patients. However, investigations of non...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2013.05.002
更新日期:2013-09-25 00:00:00
abstract:OBJECTIVE:The current study was designed to investigate the association between serum thyroid hormones and thyroid-stimulating hormone (TSH) levels with lipid profile in depressive disorder. METHODS:A total of 370 depressive individuals aged 18 years and above were recruited in this cross-section study. All participan...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2017.03.055
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:Transcranial magnetic stimulation (TMS) of the dorsolateral prefrontal cortex is a brain stimulation technique widely used to treat depression. BDNF serum concentrations have been shown to be decreased in patients with major depressive disorder and can be upregulated by several antidepressive treatment strat...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2007.08.008
更新日期:2008-04-01 00:00:00
abstract:BACKGROUND:Treatment studies are lacking for patients with bipolar II disorder (BDII). The objective of this study was to compare lamotrigine (LTG) and lithium (Li) monotherapy for the treatment of BDII depression. METHODS:Patients with BDII acute depression were randomized to open-label monotherapy with LTG or Li, an...
journal_title:Journal of affective disorders
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.jad.2008.02.004
更新日期:2008-12-01 00:00:00
abstract::In order to evaluate the possible effect of glucocorticoids as neuromodulators of the hypothalamic-pituitary-somatotropic system in depression, cortisol, growth hormone (GH), and insulin-like growth factor I (IGF-I) concentrations were studied before and after oral administration of 1 mg dexamethasone at 11 p.m. in 16...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(89)90018-9
更新日期:1989-07-01 00:00:00
abstract:BACKGROUND:The relationship between temperament and sexual orientation has been poorly characterized. We have used the Affective and Emotional Composite Temperament (AFECT) model to evaluate this association in a large population sample. METHODS:Data from 16,571 subjects between 21 and 45 years old (mean age=29.1±6.3 ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2015.01.029
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:Major depressive disorder (MDD) is a heterogeneous condition and individual patients are likely to be differentially responsive to specific treatments. In an exploratory factor analysis of three rating scales, the Genome-based Therapeutic Drugs for Depression (GENDEP) trial identified three factors that were...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2017.12.035
更新日期:2018-03-15 00:00:00
abstract:BACKGROUND:Bipolar disorder (BD) broadly affects brain structure, in particular areas involved in emotion processing and cognition. In the last years, the psychiatric field's interest in machine learning approaches has been steadily growing, thanks to the potentiality of automatically discriminating patients from healt...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2019.06.019
更新日期:2019-09-01 00:00:00
abstract::Direction of weight change in depression has recently been reported to be mediated by Body Mass Index (BMI). The present study examined the relation between direction of weight change in unipolar depression, BMI, and clinical variables such as severity of depression, melancholia, chronicity and recurrence in 89 patien...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(94)90151-1
更新日期:1994-01-01 00:00:00
abstract::Severe depression is characterized by anorexia and weight loss, symptoms that could endanger the patient's nutritional state. In order to investigate the nutritional state of depressed patients we determined the following in 113 healthy controls and depressed inpatients: (1) anthropometric variables such as body weigh...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(91)90032-n
更新日期:1991-09-01 00:00:00
abstract:BACKGROUND:Emotional sensitivity involves the ability to recognize and interpret facial expressions. This is very important for interpersonal communication. Previous studies found differences in emotional sensitivity between high social anxiety (HSA) individuals and low social anxiety (LSA) individuals. However, the un...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2020.09.111
更新日期:2021-01-15 00:00:00
abstract:BACKGROUND:Socioeconomic status, as measured by education, occupation or income, is associated with depression. However, data are lacking on the psychosocial, material and behavioral mediators of these associations. We have examined the association of education, occupation and income with depression and the potential m...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2018.08.077
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:Gambling problems co-occur frequently with other psychiatric difficulties and may complicate treatment for affective disorders. This study evaluated the prevalence and correlates of gambling problems in a U. S. representative sample reporting treatment for mood problems or anxiety. METHODS:n=3007 respondent...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2016.05.023
更新日期:2016-09-15 00:00:00
abstract:BACKGROUND:Although several researches investigated Default Mode Network (DMN) alterations in individuals with anxiety disorders, up to now no studies have investigated DMN functional connectivity in non-clinical individuals with high-trait-anxiety using quantitative electroencephalography (EEG). Here, the main aim was...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2018.12.071
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:Epidemiologic surveys consistently document high rates of untreated depression, yet why this unmet need exists is only partially understood. METHODS:We compared untreated depressed, treated depressed and "healthy" subjects on sociodemographic characteristics, need for treatment, and help-seeking attitudes u...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(98)00116-5
更新日期:1999-05-01 00:00:00
abstract:BACKGROUND:The health benefits of physical activity (PA) have been well documented in the literature. The relationship between PA and psychological well-being (PWB) has received increasing attention. AIM:This study aimed to systematically review the measurement of PWB in PA studies and examine the major findings of th...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2019.06.024
更新日期:2019-09-01 00:00:00
abstract::All maintenance treatment programs are complicated by the issue of patient noncompliance. This report investigates factors contributing to noncompliance during a 2-year study designed to evaluate the efficacy of long-term antidepressant medication in patients with recurrent unipolar depression. Only 21 of 51 patients ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(84)90023-5
更新日期:1984-04-01 00:00:00
abstract:BACKGROUND:Previous studies have linked maternal depression to different child offspring's growth outcomes. However, its effect has not been well established. The aim of this review was to evaluate the available evidence on the effect of maternal postpartum depression on offspring weight and height growth outcomes. ME...
journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/j.jad.2017.12.013
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND:Given the poor prognosis of late-life depression, it is crucial to identify those at risk. Our objective was to construct and validate a prediction rule for an unfavourable course of late-life depression. METHODS:For development and internal validation of the model, we used The Netherlands Study of Depressi...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2018.04.026
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:Suicide remains a significant public health problem worldwide. The aim of this study was to assess the mortality trend of suicide in Serbia for the years 1991-2014. METHODS:Data on persons who died of suicide and self-inflicted injury (site codes E950-E959 revision 9 and X60-X84 revision 10 of the Internati...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2015.12.063
更新日期:2016-03-15 00:00:00
abstract:BACKGROUND:Family history studies in adults reveal strong familiality for the anxiety disorders with some specificity. The aim of the current study was to establish whether there was an elevated rate of anxiety disorders in the parents of children with anxiety disorders, and whether there was intergenerational specific...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2006.03.017
更新日期:2006-07-01 00:00:00
abstract:BACKGROUND:Antidepressant medication (ADM) is thought to reduce depressive symptoms by altering emotion-generative brain systems. However, it is unknown whether successful ADM treatment is associated with changes in psychobehavioral strategies used to regulate emotions. We examined depressive symptoms and emotion regul...
journal_title:Journal of affective disorders
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jad.2013.12.037
更新日期:2014-04-01 00:00:00