Abstract:
BACKGROUND:Evaluations of clinical depression are traditionally based on verbal information. Nonverbal expressive behavior, however, being associated with a person's reflexive responses, may reveal negative emotional or social processes that are not under complete control of the patients. However, investigations of nonverbal behavior in the evaluation of depressed patients are still scarce. This study examines the nonverbal behaviors of a group of Brazilian patients, associating their nonverbal behavior with severity of depression. METHODS:Forty depressed patients were evaluated at baseline (T0) and after a two-week transcranial direct current stimulation treatment (T1), according to rating scales and through a 21-category Ethogram for assessment of the frequency of nonverbal behaviors displayed during an interview. RESULTS:Behaviors that were related to negative feelings and social disinterest decreased with corresponding clinical improvement and were associated with increased severity of symptoms at T0 and greater negative affect and dissatisfaction at T1. Pro-social behaviors were associated with milder symptoms at T0 and increased after treatment. Facial, head and hand expressive movements stood out as important indicators because of their associations with severity of depression. LIMITATIONS:Duration of behaviors was not assessed and there was not a healthy control group with which to compare the findings. CONCLUSIONS:These results support the usefulness of nonverbal behavior as an evaluation technique in the assessment of clinical depression.
journal_name
J Affect Disordjournal_title
Journal of affective disordersauthors
Fiquer JT,Boggio PS,Gorenstein Cdoi
10.1016/j.jad.2013.05.002subject
Has Abstractpub_date
2013-09-25 00:00:00pages
1114-9issue
3eissn
0165-0327issn
1573-2517pii
S0165-0327(13)00360-1journal_volume
150pub_type
杂志文章abstract:BACKGROUND:Depression and anxiety are prevalent psychiatric disorders that carry significant morbidity. Pharmacological and psychosocial interventions are used to manage these conditions, but their efficacy is limited. Recent interest into the use of psychedelic-assisted therapy using ayahuasca, psilocybin or lysergic ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2019.07.076
更新日期:2019-11-01 00:00:00
abstract::We examined the value of the melancholic distinction for predicting response to 1 week of hospitalization without antidepressant drugs and to a 4-week fixed plasma level desipramine (DMI) trial in patients with unipolar non-psychotic major depression. Both DSM-III and III-R criteria were tested. Response to hospitaliz...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(90)90032-4
更新日期:1990-03-01 00:00:00
abstract:BACKGROUND:Although the clinical efficacy of electroconvulsive therapy (ECT) is well established, the underlying mechanisms of action remain elusive. The aim of this study was to elucidate structural changes of the brain following ECT in patients with major depressive disorder (MDD). METHOD:Fifteen patients with MDD u...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2015.06.051
更新日期:2015-11-01 00:00:00
abstract::Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of dopamine and norepinephrine, and therefore is of significant interest as a candidate gene in studies of affective disorders. We have carried out the linkage study between the susceptibility gene for affective disorder and tetranucleotide polymor...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(95)00004-7
更新日期:1995-05-17 00:00:00
abstract:RATIONALE:Depression is associated with coronary artery disease and increases adverse outcomes and mortality in patients with acute myocardial infarction, but the underlying pathophysiological mechanisms remain unclear. OBJECTIVE:To evaluate the effect of macrophage migration inhibitory factor (MIF) on cardiac ischemi...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2017.12.039
更新日期:2018-03-15 00:00:00
abstract::Sulpiride, in this open study of acute manic patients, had a clear antimanic action with all eight patients responding to sulpiride treatment without the need for other antipsychotic drugs. Plasma prolactin concentrations were increased and oestrogen-stimulated neurophysin concentrations decreased by sulpiride but wer...
journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章
doi:10.1016/0165-0327(89)90064-5
更新日期:1989-03-01 00:00:00
abstract:BACKGROUND:Depressive disorders affect approximately 18.8 million patients annually. Influenza, a preventable infectious disease, leads to 50 million new cases each year and up to 40,000 deaths annually. It is believed that depressive symptoms somatize and can lead to decreased immune function. This hypothesis has litt...
journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/j.jad.2011.12.037
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:We present a fully articulated protocol for the Hamilton Rating Scale for Depression (HAM-D), including item scoring rules, rater training procedures, and a data management algorithm to increase accuracy of scores prior to outcome analyses. The latter involves identifying potentially inaccurate scores as int...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2016.01.051
更新日期:2016-08-01 00:00:00
abstract:BACKGROUND:Gray matter volume reduction in specific brain regions, such as the prefrontal cortex, was found in patients with bipolar disorder and those with unipolar depression. However, few studies have directly compared gray matter volumes between bipolar disorder and unipolar depression. In addition, it is unknown w...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2018.10.106
更新日期:2019-02-15 00:00:00
abstract:BACKGROUND:Neuroimaging of psychiatric disease is challenged by the difficulty of establishing the causal role of neuroimaging abnormalities. Lesions that cause mania present a unique opportunity to understand how brain network disruption may cause mania in both lesions and in bipolar disorder. METHODS:A literature se...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2018.10.087
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:Emotional dysregulation in subjects with attention deficit and hyperactivity disorder (ADHD) is a topic of growing interest among clinicians and researchers. The present study aims at investigating components of emotional dysregulation in adults ADHD compared to subjects suffering from bipolar disorder (BD)....
journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/j.jad.2016.03.047
更新日期:2016-07-01 00:00:00
abstract:OBJECTIVE:Ethnic, social and cultural factors contribute to axis I comorbid conditions in bipolar disorder (BPD). Korea has strict laws against illicit drugs and a relatively permissive prevailing attitude toward alcohol. The present study aimed to explore the lifetime axis I comorbidity rate in patients with BPD in Ko...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2014.05.027
更新日期:2014-09-01 00:00:00
abstract:INTRODUCTION:The burden of treatment-resistant depression (TRD) in Canada requires empirical characterization to better inform clinicians and policy decision-making in mental health. Towards this aim, this study utilized the Institute for Clinical Evaluative Sciences (ICES) databases to quantify the economic burden and...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2020.07.045
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:fMRI graph theory reveals resting-state brain networks, but has never been used in pediatric OCD. METHODS:Whole-brain resting-state fMRI was acquired at 3T from 21 children with OCD and 20 age-matched healthy controls. BOLD connectivity was analyzed yielding global and local graph-theory metrics across 100 ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2015.12.071
更新日期:2016-03-15 00:00:00
abstract:BACKGROUND:Impulsivity (I) and anxiety (A) were hypothesized to be crucial clinical features in adolescents with at-risk behavior. We therefore classified them into sub-groups according to these two major dimensions. The study examined the relevance of these groups by describing their major diagnoses and behavioral cha...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(02)00455-x
更新日期:2003-05-01 00:00:00
abstract:BACKGROUND:Chronic depression (CD) is strongly associated with childhood maltreatment, which has been proposed to lead to inefficient coping styles that are characterized by abnormal affective responsiveness and dysfunctional cognitive attitudes. However, while this notion forms an important basis for psychotherapeutic...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2017.12.090
更新日期:2018-03-15 00:00:00
abstract::In order to evaluate the possible effect of glucocorticoids as neuromodulators of the hypothalamic-pituitary-somatotropic system in depression, cortisol, growth hormone (GH), and insulin-like growth factor I (IGF-I) concentrations were studied before and after oral administration of 1 mg dexamethasone at 11 p.m. in 16...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(89)90018-9
更新日期:1989-07-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to assess how seasonal changes in mood and behaviour were associated with depression and anxiety symptoms in a sample from a general population, and to investigate how prevalence figures were affected by month of questionnaire completion. METHODS:The target population included ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2007.05.002
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:In several previous biochemical and genetic studies, the Val158Met polymorphism of the gene encoding catechol-O-methyltransferase (COMT) and the C677T polymorphism of Methylenetetrahydrofolate reductase (MTHFR) have been suggested to be involved in the pathogenesis as well as the treatment response of major ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2014.03.008
更新日期:2014-06-01 00:00:00
abstract:BACKGROUND:Attention deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by deficits in self-controlling attention, behavior, and emotions. In recent years, noninvasive optical techniques, such as near infrared spectroscopy (NIRS), have been used to measure the neural correlates of phar...
journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/j.jad.2018.10.100
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:Given the poor prognosis of late-life depression, it is crucial to identify those at risk. Our objective was to construct and validate a prediction rule for an unfavourable course of late-life depression. METHODS:For development and internal validation of the model, we used The Netherlands Study of Depressi...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2018.04.026
更新日期:2018-08-01 00:00:00
abstract::There are indications of abnormalities in membrane transport processes of erythrocytes in affective disorders. Therefore, it seemed worth while to investigate possible charge heterogeneities of erythrocyte membrane proteins in psychiatric disorders applying isoelectric focusing (IEF) in one- and two-dimensional proced...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(88)90089-4
更新日期:1988-09-01 00:00:00
abstract:INTRODUCTION:Exposure to adverse childhood experience (ACE) has harmful consequences for children's health and well-being. However, it is less clear how different social processes may amplify or mitigate the effects of ACE on children's mental health. We examined how parenting stress mediates and family resilience mode...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2020.03.132
更新日期:2020-07-01 00:00:00
abstract:PURPOSE:A number of studies have underlined a 10-20% prevalence of complicated grief (CG) among caregivers of cancer patients. The study aimed at examining the relationship between pre-loss criteria for CG and post-loss diagnosis of CG and at evaluating the validity and factor structure of a predictive tool, the Invent...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2013.12.023
更新日期:2014-05-01 00:00:00
abstract:BACKGROUND:Postpartum depression (PPD) negatively impacts maternal health, parenting and development of children. Most previous studies on PPD risk factors are based on Western populations. Additionally, little is known about the association between psychosocial factors during early pregnancy period and PPD. We aimed t...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2020.03.026
更新日期:2020-05-15 00:00:00
abstract:OBJECTIVE:Suicide is a major cause of death in university students. Personality traits have been suggested as possible risk factors for suicidal behaviors. This study looked at the relationship between the personality dimensions of the Temperament and Character Inventory (TCI) and suicidal behaviors. METHOD:A total of...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2017.06.025
更新日期:2017-10-15 00:00:00
abstract:BACKGROUND:Obsessive-compulsive disorder (OCD) is increasingly conceptualized as a brain connectivity disorder. Recently, abnormalities in remote resting-state functional connectivity (FC) have been well demonstrated in the frontoparietal areas that linked impairments in large-scale intrinsic brain networks with aberra...
journal_title:Journal of affective disorders
pub_type: 杂志文章,meta分析
doi:10.1016/j.jad.2018.10.112
更新日期:2019-02-15 00:00:00
abstract:BACKGROUND:Depressive and anxiety disorders affect work functioning and cause high labour costs. AIMS:To examine and compare psychopathological characteristics of depressive and anxiety disorders in their effect on work functioning. METHOD:In 1876 working participants of the Netherlands Study of Depression and Anxiet...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2010.01.072
更新日期:2010-09-01 00:00:00
abstract:BACKGROUND:Recent evidence suggests an association between cognitive anxiety sensitivity and suicidal ideation. Cognitive anxiety sensitivity has also been implicated as a precursor to various forms of overarousal. These manifestations of overarousal (i.e., agitation, insomnia, nightmares, and anger) may account for th...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2015.12.014
更新日期:2016-03-01 00:00:00
abstract:BACKGROUND:Depression and low-grade systemic inflammation are associated risk factors for hospitalizations and mortality, although the nature of this relationship is under-investigated. METHODS:We performed multivariable Cox regressions of first hospitalization/mortality for all and specific causes vs depression sever...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2020.10.004
更新日期:2021-01-15 00:00:00