当前位置： SCI文献检索 > JOURNAL OF AFFECTIVE DISORDERS期刊下所有文献 > Correlation of proinflammatory cytokines levels and reduced gray matter volumes between patients with bipolar disorder and unipolar depression.

Correlation of proinflammatory cytokines levels and reduced gray matter volumes between patients with bipolar disorder and unipolar depression.

Abstract：

BACKGROUND:Gray matter volume reduction in specific brain regions, such as the prefrontal cortex, was found in patients with bipolar disorder and those with unipolar depression. However, few studies have directly compared gray matter volumes between bipolar disorder and unipolar depression. In addition, it is unknown whether proinflammatory cytokines play a role in the gray matter volume difference between bipolar disorder and unipolar depression. METHODS:Twenty-three patients with bipolar disorder and 23 with unipolar depression in a mildly ill state (Clinical Global Impression-Severity ≤ 3) were enrolled in our study. Each participant underwent structural magnetic resonance imaging and proinflammatory cytokines examination. Voxel-based morphometry was performed to investigate the gray matter volume difference between bipolar disorder and unipolar depression. Correlations of the proinflammatory cytokines and the gray matter volume difference were analyzed. RESULTS:Several brain regions, including the orbitofrontal cortex, lingual gyrus, inferior frontal cortex, middle frontal cortex, and planum polare, were significantly smaller in patients with bipolar disorder than in those with unipolar depression. These gray matter volume differences between bipolar disorder and unipolar depression were negatively correlated with soluble IL-6 receptor levels. DISCUSSION:Proinflammatory cytokines, especially IL-6, were associated with the gray matter volumes in bipolar disorder and unipolar depression. However, the complicated associations between proinflammatory cytokines, neurocognitive function, and gray matter volumes require further investigation.

journal_name

J Affect Disord

journal_title

Journal of affective disorders

authors

Chen MH,Chang WC,Hsu JW,Huang KL,Tu PC,Su TP,Li CT,Lin WC,Bai YM

doi

10.1016/j.jad.2018.10.106

subject

Has Abstract

pub_date

2019-02-15 00:00:00

pages

8-15

eissn

0165-0327

issn

1573-2517

pii

S0165-0327(18)30186-1

journal_volume

245

pub_type

杂志文章

相关文献

JOURNAL OF AFFECTIVE DISORDERS文献大全
  • Developing an early warning system of suicide using Google Trends and media reporting.

    abstract：BACKGROUND:Conventional surveillance systems for suicides typically suffer from a substantial time lag of six months to two years. This study aims to develop an early warning system of possible suicide outbreaks in Hong Kong using Google Trends and suicide-related media reporting. METHODS:Data on 3,534 suicides from 2...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2019.05.030

    authors： Chai Y,Luo H,Zhang Q,Cheng Q,Lui CSM,Yip PSF

    更新日期：2019-08-01 00:00:00

  • Depression in fatiguing illness: comparing patients with chronic fatigue syndrome, multiple sclerosis and depression.

    abstract：:Because depression is commonly observed in the chronic fatigue syndrome (CFS), the present study sought to determine whether the symptom pattern is similar to that seen in clinically depressed subjects (DEP). Individuals with multiple sclerosis (MS) were chosen as an additional comparison group because MS is a fatigui...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/0165-0327(96)00015-8

    authors： Johnson SK,DeLuca J,Natelson BH

    更新日期：1996-06-20 00:00:00

  • Depression-related cognitive impairment: possibilities for its pharmacological treatment.

    abstract：:Depression-related cognitive impairment (DRCI) is a condition which despite its initial treatment response, shows a progressive deterioration. No consistent therapeutic strategies have been proposed to combat this condition. This may be due to a reluctance to treat the cognitively impaired, a failure to recognise the ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章,评审

    doi：10.1016/0165-0327(95)00070-4

    authors： Mitchell AJ,Dening TR

    更新日期：1996-01-22 00:00:00

  • Nonverbal attunement between depressed patients and an interviewer predicts subsequent improvement.

    abstract：:Depressed patients' support-seeking behaviour and the responses to this behaviour by others (support-giving) are presumed to play a causal role in depression. In interactions between normals, attuning nonverbal behaviour (i.e., equalizing levels of specific behavioural activities) is important for satisfaction of the ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/0165-0327(96)00037-7

    authors： Geerts E,Bouhuys N,Van den Hoofdakker RH

    更新日期：1996-09-09 00:00:00

  • Tyrosine negatively affects flexible-like behaviour under cognitively demanding conditions.

    abstract：BACKGROUND:The catecholaminergic precursor to dopamine, tyrosine, is an important modulator of cognitive performance. A number of studies have demonstrated that the beneficial effects of tyrosine on cognitive performance are most pronounced when individuals are exposed to stressful situations, such as hypothermia. Howe...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.jad.2019.09.031

    authors： Robson A,Lim LW,Aquili L

    更新日期：2020-01-01 00:00:00

  • Indirect effect of parental depression on school victimization through adolescent depression.

    abstract：BACKGROUND:While a link between parental depression and adolescent school victimization is frequently hypothesized, studies on this association have shown mixed results. In addition, adolescent depression has been considered a potential psychosocial mechanism underlying the link between parental depression and adolesce...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2019.11.126

    authors： Chen JK,Wu C,Chang CW,Wei HS

    更新日期：2020-02-15 00:00:00

  • Chronotype and seasonality: morningness is associated with lower seasonal mood and behavior changes in the Old Order Amish.

    abstract：BACKGROUND:Several studies documented that lower scores on the Morningness-Eveningness Questionnaire (MEQ) are associated with a higher global seasonality of mood (GSS). As for the Modern Man artificial lighting predominantly extends evening activity and exposure to light, and as evening bright light phase is known to ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2014.11.039

    authors： Zhang L,Evans DS,Raheja UK,Stephens SH,Stiller JW,Reeves GM,Johnson M,Ryan KA,Weizel N,Vaswani D,McLain H,Shuldiner AR,Mitchell BD,Hsueh WC,Snitker S,Postolache TT

    更新日期：2015-03-15 00:00:00

  • Medical comorbidity and health-related quality of life in bipolar disorder across the adult age span.

    abstract：BACKGROUND:Little is known about medical comorbidity or health-related quality of life (HRQOL) in bipolar disorder across the adult age span, especially in public sector patients. METHODS:We obtained cross-sectional demographic, clinical, and functional ratings for 330 veterans hospitalized for bipolar disorder with M...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2004.12.006

    authors： Fenn HH,Bauer MS,Altshuler L,Evans DR,Williford WO,Kilbourne AM,Beresford TP,Kirk G,Stedman M,Fiore L,VA Cooperative Study #430 Team.

    更新日期：2005-05-01 00:00:00

  • Mental health scales and psychiatric diagnoses: responses to GHQ-12, K-10 and CIDI across the lifespan.

    abstract：BACKGROUND:Surveys based on complex interviews like CIDI report very low rates of affective disorder in older people, perhaps because the lengthy, convoluted questions present a special challenge to aged respondents. By contrast, mental health scales like the GHQ-12 and K-10 show much less change in score with age. Bef...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2009.06.038

    authors： O'Connor DW,Parslow RA

    更新日期：2010-03-01 00:00:00

  • Schizoaffective disorder diagnosed according to different diagnostic criteria--systematic literature search and meta-analysis of key clinical characteristics and heterogeneity.

    abstract：BACKGROUND:Schizoaffective disorder is viewed as a heterogeneous diagnosis among psychotic illnesses. Different diagnostic systems differ in their definition with DSM (-IIIR, -IV, and -V) providing a narrower definition than RDC and ICD-10. It is unclear whether this difference is reflected in patient samples diagnosed...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章,meta分析,评审

    doi：10.1016/j.jad.2013.12.001

    authors： Pagel T,Franklin J,Baethge C

    更新日期：2014-03-01 00:00:00

  • Prevalence of complicated grief in a representative population-based sample.

    abstract：BACKGROUND:Complicated grief (CG) has been proposed as a distinct diagnostic category in the next edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-V). However, few epidemiological studies to date have measured CG in the general population. METHODS:Prevalence of CG, sociodemographic characteris...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2010.11.032

    authors： Kersting A,Brähler E,Glaesmer H,Wagner B

    更新日期：2011-06-01 00:00:00

  • Severity of bipolar disorder is associated with impairment of response inhibition.

    abstract：BACKGROUND:Pathological impulsivity in bipolar disorder could be related to deficiencies in mechanisms involved in attention or response inhibition. We investigated these mechanisms in subjects with bipolar disorder and examined relationships to severity of course of illness, use of medication, affective state, age, ed...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2008.10.022

    authors： Swann AC,Lijffijt M,Lane SD,Steinberg JL,Moeller FG

    更新日期：2009-07-01 00:00:00

  • Impact of early onset bipolar disorder on family functioning: adolescents' perceptions of family dynamics, communication, and problems.

    abstract：OBJECTIVE:This research investigated the impact of adolescent onset bipolar illness on perceived family functioning in stabilized bipolar I (B) and unipolar (U) probands, and normal controls (C). METHOD:Sample N=119: 44 bipolar 1(17 M, 27 F), 30 unipolar (9 M, 21 F), and 45 controls (19 M, 26 F). Mean ages: 19.9, 18.5...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/s0165-0327(00)00281-0

    authors： Robertson HA,Kutcher SP,Bird D,Grasswick L

    更新日期：2001-09-01 00:00:00

  • High frequency heart-rate variability predicts adolescent depressive symptoms, particularly anhedonia, across one year.

    abstract：BACKGROUND:Few prospective studies examine the link between lower heart rate variability (HRV) and depression symptoms in adolescents. A recent animal model specifically links HRV to anhedonia, suggesting a potential translational model for human research. METHOD:We investigated the association between spectral measur...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2016.02.040

    authors： Vazquez L,Blood JD,Wu J,Chaplin TM,Hommer RE,Rutherford HJ,Potenza MN,Mayes LC,Crowley MJ

    更新日期：2016-05-15 00:00:00

  • Genetic risk for bipolar disorder and psychopathology from childhood to early adulthood.

    abstract：BACKGROUND:Studying the phenotypic manifestations of increased genetic liability for Bipolar Disorder (BD) can increase understanding of this disorder. AIMS:We assessed whether genetic risk for BD was associated with childhood psychopathology and features of hypomania in young adulthood within a large population-based...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2018.12.091

    authors： Mistry S,Escott-Price V,Florio AD,Smith DJ,Zammit S

    更新日期：2019-03-01 00:00:00

  • The utility of a classificatory decision tree approach to assist clinical differentiation of melancholic and non-melancholic depression.

    abstract：BACKGROUND:Studies suggest that differentiating melancholic from non-melancholic depressive disorders is advanced by use of illness course as well as symptom variables but, in practice, potentially differentiating variables are generally positioned as having equal value. Judging that differentiating features are more l...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2015.03.057

    authors： Parker G,McCraw S,Hadzi-Pavlovic D

    更新日期：2015-07-15 00:00:00

  • Prevalence of distress, comorbid conditions and well being in the general population.

    abstract：BACKGROUND:The purposes of this paper are to determine the prevalence of distress in the community, to identify its determinants and to assess its relationship to somatic conditions and subjective well being. METHODS:Distress and associated factors were investigated in a random sample of 5000 participants (35-74 years...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2010.10.041

    authors： Wiltink J,Beutel ME,Till Y,Ojeda FM,Wild PS,Münzel T,Blankenberg S,Michal M

    更新日期：2011-05-01 00:00:00

  • Assessment of prevalence and determinants of posttraumatic stress disorder in survivors of earthquake in Pakistan using Davidson Trauma Scale.

    abstract：INTRODUCTION:Pakistan's 2005 earthquake claimed almost 87,000 lives and displaced millions. The present study sought to assess PTSD prevalence among earthquake survivors, to evaluate its determinants, and to identify protective factors that suggest future interventions in the aftermath of disasters. METHODS:In a cross...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2011.12.023

    authors： Ali M,Farooq N,Bhatti MA,Kuroiwa C

    更新日期：2012-02-01 00:00:00

  • Olanzapine versus haloperidol in schizoaffective disorder, bipolar type.

    abstract：BACKGROUND:The present analysis was performed on data from a subsample of patients with schizoaffective disorder, bipolar type, who participated in a multicenter, double-blind study comparing olanzapine to haloperidol. METHODS:Patients with schizoaffective disorder bipolar type, characterized as currently manic, mixed...

    journal_title：Journal of affective disorders

    pub_type： 临床试验,杂志文章,多中心研究,随机对照试验

    doi：10.1016/s0165-0327(00)00303-7

    authors： Tohen M,Zhang F,Keck PE,Feldman PD,Risser RC,Tran PV,Breier A

    更新日期：2001-12-01 00:00:00

  • The prevalence of depression in Alzheimer's disease and vascular dementia in a population sample.

    abstract：BACKGROUND:Previous studies have shown that depression is more prevalent in vascular dementia than Alzheimer's disease (AD). Subjects for these studies were either psychiatry or neurology patients, raising the issue of whether factors leading to treatment might have introduced sampling bias. METHODS:Data for the prese...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/s0165-0327(98)00070-6

    authors： Newman SC

    更新日期：1999-01-01 00:00:00

  • The 3-year course and outcome of patients with major depression and silent cerebral infarction.

    abstract：:We retrospectively investigated the relationship between major depression and silent cerebral infarction (SCI) over a 3-year period in 64 patients older than 50 years of age with unipolar depression. All patients underwent magnetic resonance imaging (MRI) at their first admission for depression and were classified int...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/s0165-0327(97)00148-1

    authors： Yanai I,Fujikawa T,Horiguchi J,Yamawaki S,Touhouda Y

    更新日期：1998-01-01 00:00:00

  • Maternal attachment style and psychiatric history as independent predictors of mood symptoms in the immediate postpartum period.

    abstract：BACKGROUND:There is evidence that both a past history of psychiatric illness and insecure attachment put women at risk for mood disturbances in the postpartum period. The aim of this study was to ascertain whether maternal insecure attachment is a risk factor for mood symptoms in the immediate postpartum period indepen...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2017.01.039

    authors： Croce Nanni R,Troisi A

    更新日期：2017-04-01 00:00:00

  • Subcortical structural volumes in recently remitted first episode mania.

    abstract：BACKGROUND:Magnetic resonance imaging (MRI) studies have yielded inconsistent findings with regard to subcortical volumetric abnormalities in patients with bipolar I disorder. Duration of illness and long term medication intake could have confounded the findings. METHOD:Volumes of nine subcortical structures were comp...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2017.06.051

    authors： Arumugham SS,Torres IJ,Lang DJ,Su W,Lam RW,Honer WG,Yatham LN

    更新日期：2017-11-01 00:00:00

  • Duration of subsequent episodes and periods of recovery in recurrent major depression.

    abstract：BACKGROUND:Little is known about the duration of subsequent depressive episodes and periods of recovery, and much is based on potentially biased retrospective data. We therefore prospectively assessed whether duration of depressive episodes and recoveries is correlated within subjects and across episodes, and whether d...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.jad.2009.12.013

    authors： de Jonge P,Conradi HJ,Kaptein KI,Bockting CL,Korf J,Ormel J

    更新日期：2010-09-01 00:00:00

  • Predictors of acute stress disorder severity.

    abstract：BACKGROUND:The DSM-IV diagnosis of acute stress disorder (ASD) describes a posttraumatic reaction that occurs two to twenty-eight days following a trauma and involves symptoms of intrusion, avoidance, hyper-arousal and dissociation. A better understanding of ASD and its pathogenesis could lead to improved post-trauma h...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2013.01.041

    authors： Suliman S,Troeman Z,Stein DJ,Seedat S

    更新日期：2013-07-01 00:00:00

  • Parental concordance for affective disorders: psychopathology in offspring.

    abstract：:This paper examines the effects of parental concordance for affective disorders and psychopathology among the 219 offspring of probands with major depression and normal controls. The lifetime prevalence of psychiatric disorders was significantly higher among the spouses of depressed probands as compared to those of no...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/0165-0327(88)90025-0

    authors： Merikangas KR,Prusoff BA,Weissman MM

    更新日期：1988-11-01 00:00:00

  • The association between anti-inflammatory effects of long-term lithium treatment and illness course in Bipolar Disorder.

    abstract：INTRODUCTION:Altered levels of acute-phase proteins are often described in different conditions in BD. Nevertheless, data on the association between lithium treatment and inflammatory markers in the long-term course of BD are still missing. The aim of the study was to examine the long-term course of BD concerning long-...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2020.11.063

    authors： Queissner R,Lenger M,Birner A,Dalkner N,Fellendorf F,Bengesser S,Platzer M,Hamm C,Maget A,Reininghaus B,Ratzenhofer M,Schuller J,Mangge H,Kapfhammer HP,Reininghaus EZ

    更新日期：2021-02-15 00:00:00

  • Maintenance therapy with second generation antipsychotics for bipolar disorder - A systematic review and meta-analysis.

    abstract：BACKGROUND:Second generations antipsychotics (SGA) are frequently used for maintenance treatment in bipolar disorder. We systematically reviewed the efficacy and long-term effects of treatment with SGA, regardless of treatment strategy (SGA administered either as monotherapy or as adjunctive therapy), in comparison to ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章,meta分析,评审

    doi：10.1016/j.jad.2017.02.012

    authors： Lindström L,Lindström E,Nilsson M,Höistad M

    更新日期：2017-04-15 00:00:00

  • Changes in miRNA-132 and miR-124 levels in non-treated and citalopram-treated patients with depression.

    abstract：BACKGROUND:Neurotrophins including brain-derived neurotropic factor (BDNF) are implicated in the pathogenesis of major depressive disorder (MDD). Yet, the roles of brain-specific BDNF-related miRNAs miR-132 and miR-124 are unclear. METHODS:We enrolled 45 treatment-free patients with MDD, 32 citalopram-treated patients...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2017.11.090

    authors： Fang Y,Qiu Q,Zhang S,Sun L,Li G,Xiao S,Li X

    更新日期：2018-02-01 00:00:00

  • Changing of suicide rates in China, 2002-2015.

    abstract：BACKGROUND:The overall suicide rate in China has dropped substantially since the 1990s, with patterns changing significantly. This study aims to further explore the latest changes in suicide rates in China. METHODS:Data on gender-age-specific suicide rates for rural and urban residents aged 15 years and above were ret...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2018.07.043

    authors： Jiang H,Niu L,Hahne J,Hu M,Fang J,Shen M,Xiao S

    更新日期：2018-11-01 00:00:00