Current and future status of ovulation induction in polycystic ovary syndrome.

abstract：:Mucin glycoproteins are major constituents of the glycocalyx that covers mucosal epithelium. Two broad classes of mucins exist: membrane-associated and secretory. Of the secreted mucins, those with cysteine-rich regions are thought to polymerize through disulphide bonds. Among these gel-forming mucins are MUC2, MUC5AC...

journal_title：Human reproduction update

authors： Lagow E,DeSouza MM,Carson DD

更新日期：1999-07-01 00:00:00

abstract：:The signals and mechanisms that synchronize the timing of human parturition remain a mystery and a better understanding of these processes is essential to avert adverse pregnancy outcomes. Although our insights into human labor initiation have been informed by studies in animal models, the timing of parturition relati...

journal_title：Human reproduction update

authors： Menon R,Bonney EA,Condon J,Mesiano S,Taylor RN

更新日期：2016-09-01 00:00:00

abstract：:There has been an improvement in the blastocyst rates achieved following in-vitro embryo production that can largely be attributed to improved embryo culture conditions based on an increased knowledge of the in-vivo environment, as well as the metabolic needs of the embryo. Despite this, in-vitro oocyte maturation (IV...

journal_title：Human reproduction update

authors： Sutton ML,Gilchrist RB,Thompson JG

更新日期：2003-01-01 00:00:00

abstract：:BACKGROUND Angiogenesis, i.e. the development of new blood vessels from pre-existing ones, represents an integral part in the pathogenesis of endometriosis. During the last decade, an increasing number of studies have therefore focused on the anti-angiogenic treatment of the disease. The present review provides a syst...

journal_title：Human reproduction update

authors： Laschke MW,Menger MD

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Approximately half recurrent miscarriage (RM) cases remain unexplained after standard investigations. Secondary RM (SRM) is, in contrast to primary RM, preceded by a birth, which increases the transfer of fetal cells into the maternal circulation. Mothers of boys are often immunized against male-specific min...

journal_title：Human reproduction update

authors： Nielsen HS

更新日期：2011-07-01 00:00:00

abstract：:This report describes the ethical and legal aspects of assisted reproductive technologies (ART) that have been instituted in European countries. The data were collected from questionnaires circulated to fertility centres in 39 countries in Europe. Ninety six ART centres were located in 30 of these countries. Nine coun...

journal_title：Human reproduction update

authors： Schenker JG

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:The main objective of individualization of treatment in IVF is to offer every single woman the best treatment tailored to her own unique characteristics, thus maximizing the chances of pregnancy and eliminating the iatrogenic and avoidable risks resulting from ovarian stimulation. Personalization of treatmen...

journal_title：Human reproduction update

authors： La Marca A,Sunkara SK

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Fear from increased cancer risk is one of the most significant reasons for low acceptance of reliable contraceptive methods and low compliance. METHODS:In this review, we included all cohort and case-control studies published in English up to December 2008. They were identified through a search of the liter...

journal_title：Human reproduction update

authors： Cibula D,Gompel A,Mueck AO,La Vecchia C,Hannaford PC,Skouby SO,Zikan M,Dusek L

更新日期：2010-11-01 00:00:00

abstract：:The human ovary is a dynamic organ which continually changes in size and activity through life, as an integral part of the changes that the female is going through before during and after her reproductive life. Following the rapid increase in the use of transvaginal scan in recent years, the measurement of ovarian vol...

journal_title：Human reproduction update

authors： Lass A,Brinsden P

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:Worldwide, placenta-related complications contribute to adverse pregnancy outcomes, such as pre-eclampsia, fetal growth restriction and preterm birth, with implications for the future health of mothers and offspring. The placenta develops in the periconception period and forms the interface between mother an...

journal_title：Human reproduction update

authors： Reijnders IF,Mulders AGMGJ,van der Windt M,Steegers EAP,Steegers-Theunissen RPM

更新日期：2019-01-01 00:00:00

abstract：:Amenorrhoea associated with reduced caloric intake and strenuous exercise leads to hypoestrogenism and is associated with clinical manifestations that include disordered eating, stress fractures, osteoporosis, and, as recently reported, a potential increase in the risk of premature cardiovascular disease. Disordered e...

journal_title：Human reproduction update

authors： De Souza MJ,Williams NI

更新日期：2004-09-01 00:00:00

abstract：:This review presents detailed risk estimates from relevant epidemiological and other studies on the comparative safety of second and third generation oral contraceptives (OC). Written with the intention of presenting a repository of the available information, it also discourses briefly into the symptomatology and diag...

journal_title：Human reproduction update

authors： Edwards RG,Cohen J

更新日期：1999-11-01 00:00:00

abstract：:Pregnancy induces physiological alterations in thyroid function which may make difficult the interpretation of results of thyroid hormone measurement. A state of hyperstimulation of the thyroid gland is common in early pregnancy. In a few cases, thyroid hormone values will deviate from the normal range, which correspo...

journal_title：Human reproduction update

authors： Rodien P,Jordan N,Lefèvre A,Royer J,Vasseur C,Savagner F,Bourdelot A,Rohmer V

更新日期：2004-03-01 00:00:00

abstract：:The examination of fetal cells, specifically erythroblasts, and cell-free fetal DNA from the blood of pregnant women is currently the subject of intense research with the aim of developing new risk-free methods for prenatal diagnosis. An unexpected finding made during these studies was that the traffic of fetal erythr...

journal_title：Human reproduction update

authors： Hahn S,Holzgreve W

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:The aim of this systematic review and meta-analysis was to evaluate whether the addition of GnRH agonist for luteal support in ICSI/IVF cycles enhances the probability of live birth. METHODS:Systematic literature search (MEDLINE, EMBASE, CENTRAL and RCT registries) was conducted to identify relevant randomi...

journal_title：Human reproduction update

authors： Kyrou D,Kolibianakis EM,Fatemi HM,Tarlatzi TB,Devroey P,Tarlatzis BC

更新日期：2011-11-01 00:00:00

abstract：:Varicocele is often cited as the most common cause of male factor infertility. Arguments in support of this statement include reports of increased prevalence of varicocele in populations of infertile men compared with fertile or otherwise unselected men, association of varicocele with abnormal semen parameters, and im...

journal_title：Human reproduction update

authors： Redmon JB,Carey P,Pryor JL

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Important roles for G-protein-coupled receptors (GPCRs) have been identified in the maternal physiological adaptations to pregnancy and in the pathogenesis of preeclampsia. On this basis, GPCRs are potential therapeutic targets for preeclampsia. OBJECTIVES AND RATIONALE:In this review, vasopressin and apeli...

journal_title：Human reproduction update

authors： Conrad KP

更新日期：2016-09-01 00:00:00

abstract：:Ovarian follicular development occurs in a hierarchical manner with each follicle having a unique biochemical composition at any moment in time. It has long been understood that a precise coordination between the growth and maturation of the oocyte and adjacent follicular cells (i.e. somatic cells) is essential in ord...

journal_title：Human reproduction update

authors： Juengel JL,McNatty KP

更新日期：2005-03-01 00:00:00

abstract：:The effects on reproductive tract development in male rats, of neonatal exposure to potent (reference) oestrogens, diethylstilboestrol (DES) and ethinyl oestradiol (EE), with those of two environmental oestrogens, octylphenol and hisphenol A were systematically compared. Other treatments, such as administration of a g...

journal_title：Human reproduction update

authors： Williams K,McKinnell C,Saunders PT,Walker M,Fisher JS,Turner KJ,Atanassova N,Sharpe M

更新日期：2001-05-01 00:00:00

abstract：:Syncytin is a membrane protein derived from the envelope gene of an endogenous retrovirus of the HERV-W family. The gene appears to be almost exclusively expressed in placenta; the protein was found in particular in syncytiotrophoblast. After transfection into various cell types it has proven to be a very fusogenic pr...

journal_title：Human reproduction update

authors： Pötgens AJ,Drewlo S,Kokozidou M,Kaufmann P

更新日期：2004-11-01 00:00:00

abstract：:Endometriosis is considered primarily a disease of the endometrial-subendometrial unit or archimetra. The clinical picture of endometriosis characterises this disease as a hyperactivation of genuine archimetrial functions such as proliferation, inflammatory defence and peristalsis. While the aetiology of the disease r...

journal_title：Human reproduction update

authors： Leyendecker G,Kunz G,Noe M,Herbertz M,Mall G

更新日期：1998-09-01 00:00:00

abstract：:After colonization of the gonad, mouse female germ cells enter into the prophase of the first meiotic division as a mid-gestational hallmark of gender. Perinatally, oocytes interact with granulosa cells to form primordial follicles which, with cyclic periodicity, enter into a 3-week growth phase that culminates in mei...

journal_title：Human reproduction update

authors： Amleh A,Dean J

更新日期：2002-09-01 00:00:00

abstract：:Sperm transport from the cervix into the tube is an important uterine function within the process of reproduction. This function is exerted by uterine peristalsis and is controlled by the dominant ovarian structure via a cascade of endocrine events. The uterine peristaltic activity involves only the stratum subvascula...

journal_title：Human reproduction update

authors： Kunz G,Herbertz M,Noe M,Leyendecker G

更新日期：1998-09-01 00:00:00

abstract：:Laparoscopic and hysteroscopic surgery have changed the management of many gynaecological disorders. Procedures that previously required a long duration of hospitalization can now be done on an outpatient basis or with a short hospital stay. Surgical treatment remains the definitive and universal treatment of ectopic ...

journal_title：Human reproduction update

authors： Tulandi T

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:Sirtuins (SIRT1-7) are a family of NAD+-dependent deacetylases that catalyze post-translational modifications of proteins. Together, they respond to metabolic challenges, inflammatory signals or hypoxic/oxidative stress, and are associated with aging and longevity. The role of Sirtuins in the regulation of f...

journal_title：Human reproduction update

authors： Tatone C,Di Emidio G,Barbonetti A,Carta G,Luciano AM,Falone S,Amicarelli F

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:The existence of stem/progenitor cells in the endometrium was postulated many years ago, but the first functional evidence was only published in 2004. The identification of rare epithelial and stromal populations of clonogenic cells in human endometrium has opened an active area of research on endometrial st...

journal_title：Human reproduction update

authors： Gargett CE,Schwab KE,Deane JA

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Threatened miscarriage affects one in five women and is associated with significant emotional distress. The uncertainty around the prognosis of threatened miscarriage makes it equally challenging to the healthcare professionals. Various biochemical markers have been investigated in the past to predict the ou...

journal_title：Human reproduction update

authors： Pillai RN,Konje JC,Tincello DG,Potdar N

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Mast cells (MCs) are the classical mediators of allergy, however, their importance in the development of innate and adaptive immune responses is increasingly being recognized. Herein, the present MC literature is summarized, with particular focus on studies of MCs in the endometrium and myometrium, and their...

journal_title：Human reproduction update

authors： Menzies FM,Shepherd MC,Nibbs RJ,Nelson SM

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Because of the substantial energy demands of reproduction, the brain must temper the fertility of individuals to match nutritional availability. Under-nutrition is associated with infertility in humans and animals. The brain uses adipose- and gut-derived hormones, such as leptin, insulin and ghrelin, to modu...

journal_title：Human reproduction update

authors： Evans JJ,Anderson GM

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Anti-Müllerian hormone (AMH) is an established marker of ovarian reserve and a good predictor of poor or excessive ovarian response after controlled hyperstimulation. However, it is unclear whether it can predict the ultimate outcome of assisted conception, live birth. We undertook a systematic review and me...

journal_title：Human reproduction update

authors： Iliodromiti S,Kelsey TW,Wu O,Anderson RA,Nelson SM

更新日期：2014-07-01 00:00:00