Physiological aspects and clinical sequelae of energy deficiency and hypoestrogenism in exercising women.

abstract：:Nitric oxide (NO) is an important mediator of paracrine interactions, especially within the vascular system. It is a powerful inhibitor of platelet aggregation and a potent vasodilator. NO is also a neurotransmitter and it plays a role in cell-mediated cytotoxicity. NO-generating enzymes (nitric oxide synthases, NOS) ...

journal_title：Human reproduction update

authors： Cameron IT,Campbell S

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:Threatened miscarriage affects one in five women and is associated with significant emotional distress. The uncertainty around the prognosis of threatened miscarriage makes it equally challenging to the healthcare professionals. Various biochemical markers have been investigated in the past to predict the ou...

journal_title：Human reproduction update

authors： Pillai RN,Konje JC,Tincello DG,Potdar N

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:A dynamic balance between pro- and anti-inflammatory factors contributes to regulating human female reproduction. Chronic low-grade inflammation has been detected in several female reproductive conditions, from anovulation to embryo implantation failure. C-reactive protein (CRP) is a reliable marker of infla...

journal_title：Human reproduction update

authors： Brouillet S,Boursier G,Anav M,Du Boulet De La Boissière B,Gala A,Ferrieres-Hoa A,Touitou I,Hamamah S

更新日期：2020-09-01 00:00:00

abstract：:Cryopreservation of testicular tissue might benefit prepubertal boys who must undergo chemotherapy or radiotherapy. Cryopreservation of testicular tissue and testicular cells for intracytoplasmic sperm injection (ICSI) is feasible and widely applied. Testicular tissue from prepubertal boys can also be frozen, by apply...

journal_title：Human reproduction update

authors： Hovatta O

更新日期：2001-07-01 00:00:00

abstract：:Conservative management of at least part of both the ovary and uterus can be proposed in patients with borderline ovarian tumour, in order to preserve fertility potential. This conservative management could be carried out even in patients with borderline ovarian tumour associated with non-invasive peritoneal implants ...

journal_title：Human reproduction update

authors： Morice P,Camatte S,Wicart-Poque F,Atallah D,Rouzier R,Pautier P,Pomel C,Lhommé C,Duvillard P,Castaigne D

更新日期：2003-03-01 00:00:00

abstract：:The clinical significance of micro-organisms in semen samples of asymptomatic subfertile patients is a matter of constant debate. Usually little attention is paid to anaerobic bacteria as they are sensitive to transportation and culturing, and differentiation is difficult, costly and time-consuming. In the present stu...

journal_title：Human reproduction update

authors： Eggert-Kruse W,Rohr G,Ströck W,Pohl S,Schwalbach B,Runnebaum B

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:The cystic fibrosis transmembrane conductance regulator (CFTR) is a cAMP-activated Cl(-) and HCO(3)(-) conducting channel, mutations of which are known to be associated with male infertility. However, the underlying mechanisms remain elusive. METHODS:Literature databases were searched for papers on the topi...

journal_title：Human reproduction update

authors： Chen H,Ruan YC,Xu WM,Chen J,Chan HC

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Clinical trials yield discrepant information about the impact of hormone therapy on verbal memory and executive function. This issue is clinically relevant because declines in verbal memory are the earliest predictor of Alzheimer's disease and declines in executive function are central to some theories of no...

journal_title：Human reproduction update

authors： Maki PM,Sundermann E

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:The prevalence of congenital uterine anomalies in high-risk women is unclear, as several different diagnostic approaches have been applied to different groups of patients. This review aims to evaluate the prevalence of such anomalies in unselected populations and in women with infertility, including those un...

journal_title：Human reproduction update

authors： Chan YY,Jayaprakasan K,Zamora J,Thornton JG,Raine-Fenning N,Coomarasamy A

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Transfer of more than a single embryo in an IVF cycle comes with the finite possibility of a multiple gestation. Even a twin pregnancy confers significant risk to both mother and babies. The move to single-embryo transfer for all patients will be greatly facilitated by the ability to quantify embryo viabilit...

journal_title：Human reproduction update

authors： Gardner DK,Meseguer M,Rubio C,Treff NR

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Endometriosis is recognized as a steroid-dependent disorder; however, the precise roles of nuclear receptors (NRs) in steroid responsiveness and other signaling pathways are not well understood. OBJECTIVE AND RATIONALE:Over the past several years, a number of paradigm-shifting breakthroughs have occurred in...

journal_title：Human reproduction update

authors： Yilmaz BD,Bulun SE

更新日期：2019-07-01 00:00:00

abstract：:Great progress had been achieved during the last 20 years in the field of ovulation induction in patients with polycystic ovary syndrome (PCOS). Clomiphene citrate remains the first line of treatment for all anovulatory women with PCOS, since in properly selected patients the cumulative pregnancy rate approaches that ...

journal_title：Human reproduction update

authors： Messinis IE,Milingos SD

更新日期：1997-05-01 00:00:00

abstract：:The improved long-term survival of adolescents and young women treated for cancer has resulted in an increased focus on the effects of chemotherapy on ovarian function and its preservation. These women may seek advice and treatment regarding their reproductive status, including ways of preserving their fertility and p...

journal_title：Human reproduction update

authors： Lutchman Singh K,Davies M,Chatterjee R

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:There have been conflicting results in randomized trials of the effects of laparoscopic uterosacral nerve ablation (LUNA) in chronic pelvic pain. Our objective was to perform a meta-analysis using individual patient data (IPD) to provide the most comprehensive and reliable assessment of the effectiveness of ...

journal_title：Human reproduction update

authors： Daniels JP,Middleton L,Xiong T,Champaneria R,Johnson NP,Lichten EM,Sutton C,Vercellini P,Gray R,Hills RK,Jones KD,Aimi G,Khan KS,International LUNA IPD Meta-analysis Collaborative Group.

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Mild ovarian stimulation has emerged as an alternative to conventional IVF with the advantages of being more patient-friendly and less expensive. Inadequate data on pregnancy outcomes and concerns about the cycle cancellation rate (CCR) have prevented mild, or low-dose, IVF from gaining wide acceptance. OBJ...

journal_title：Human reproduction update

authors： Datta AK,Maheshwari A,Felix N,Campbell S,Nargund G

更新日期：2020-11-04 00:00:00

abstract：:The examination of fetal cells, specifically erythroblasts, and cell-free fetal DNA from the blood of pregnant women is currently the subject of intense research with the aim of developing new risk-free methods for prenatal diagnosis. An unexpected finding made during these studies was that the traffic of fetal erythr...

journal_title：Human reproduction update

authors： Hahn S,Holzgreve W

更新日期：2002-11-01 00:00:00

abstract：:BACKGROUND Angiogenesis, i.e. the development of new blood vessels from pre-existing ones, represents an integral part in the pathogenesis of endometriosis. During the last decade, an increasing number of studies have therefore focused on the anti-angiogenic treatment of the disease. The present review provides a syst...

journal_title：Human reproduction update

authors： Laschke MW,Menger MD

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Spermatogenesis culminates in production of one of the most highly differentiated cells in biology, the spermatozoon. The gametes that emerge from the testes are, however, functionally immature and only acquire full functionality once they have completed a process of post-testicular maturation in the epididy...

journal_title：Human reproduction update

authors： Dun MD,Aitken RJ,Nixon B

更新日期：2012-07-01 00:00:00

abstract：:Ca(2+) is a ubiquitous intracellular messenger which encodes information by temporal and spatial patterns of concentration. In spermatozoa, several key functions, including acrosome reaction and motility, are regulated by cytoplasmic Ca(2+) concentration. Despite the very small size and apparent structural simplicity ...

journal_title：Human reproduction update

authors： Jimenez-Gonzalez C,Michelangeli F,Harper CV,Barratt CL,Publicover SJ

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:Estrogens are known to orchestrate reproductive events and to regulate the immune system during infections and following tissue damage. Recent findings suggest that, in the absence of any danger signal, estrogens trigger the physiological expansion and functional specialization of macrophages, which are immu...

journal_title：Human reproduction update

authors： Pepe G,Locati M,Della Torre S,Mornata F,Cignarella A,Maggi A,Vegeto E

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Important roles for G-protein-coupled receptors (GPCRs) have been identified in the maternal physiological adaptations to pregnancy and in the pathogenesis of preeclampsia. On this basis, GPCRs are potential therapeutic targets for preeclampsia. OBJECTIVES AND RATIONALE:In this review, vasopressin and apeli...

journal_title：Human reproduction update

authors： Conrad KP

更新日期：2016-09-01 00:00:00

abstract：:Maternal use of marijuana, in which the exocannabinoid Delta(9)-tetrahydrocannabinol is the most active psychoactive ingredient, is known to have adverse effects on various aspects of reproduction including ovulation, spermatogenesis, implantation and pregnancy duration. Endogenous cannabinoids of which Anandamide is ...

journal_title：Human reproduction update

authors： Taylor AH,Ang C,Bell SC,Konje JC

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Sirtuins (SIRT1-7) are a family of NAD+-dependent deacetylases that catalyze post-translational modifications of proteins. Together, they respond to metabolic challenges, inflammatory signals or hypoxic/oxidative stress, and are associated with aging and longevity. The role of Sirtuins in the regulation of f...

journal_title：Human reproduction update

authors： Tatone C,Di Emidio G,Barbonetti A,Carta G,Luciano AM,Falone S,Amicarelli F

更新日期：2018-05-01 00:00:00

abstract：:In those clinical situations in which an immediate and profound suppression of gonadotrophins is desired, LHRH agonists have the disadvantage of producing an initial stimulatory effect on hormone secretion. Therefore, the use of GnRH antagonists which cause an immediate and dose-related inhibition of LH and FSH by com...

journal_title：Human reproduction update

authors： Reissmann T,Schally AV,Bouchard P,Riethmiiller H,Engel J

更新日期：2000-07-01 00:00:00

abstract：:Syncytin is a membrane protein derived from the envelope gene of an endogenous retrovirus of the HERV-W family. The gene appears to be almost exclusively expressed in placenta; the protein was found in particular in syncytiotrophoblast. After transfection into various cell types it has proven to be a very fusogenic pr...

journal_title：Human reproduction update

authors： Pötgens AJ,Drewlo S,Kokozidou M,Kaufmann P

更新日期：2004-11-01 00:00:00

abstract：:Varicocele is often cited as the most common cause of male factor infertility. Arguments in support of this statement include reports of increased prevalence of varicocele in populations of infertile men compared with fertile or otherwise unselected men, association of varicocele with abnormal semen parameters, and im...

journal_title：Human reproduction update

authors： Redmon JB,Carey P,Pryor JL

更新日期：2002-01-01 00:00:00

abstract：:This report describes the ethical and legal aspects of assisted reproductive technologies (ART) that have been instituted in European countries. The data were collected from questionnaires circulated to fertility centres in 39 countries in Europe. Ninety six ART centres were located in 30 of these countries. Nine coun...

journal_title：Human reproduction update

authors： Schenker JG

更新日期：1997-03-01 00:00:00

abstract：:Androgen levels are measured in today's clinical practice almost exclusively by immunoassays. The androgen that is most frequently determined is testosterone (T), but sometimes also the levels of other testicular, ovarian and adrenal androgens such as 5alpha-dihydrotestosterone, androstenedione, dehydroepiandrosterone...

journal_title：Human reproduction update

authors： Roy P,Alevizaki M,Huhtaniemi I

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:IUI for unexplained infertility can be performed in a natural cycle or in combination with ovarian stimulation. A disadvantage of ovarian stimulation is an increased risk of multiple pregnancies with its inherent maternal and neonatal complication risks. Stimulation agents for ovarian stimulation are clomiph...

journal_title：Human reproduction update

authors： Danhof NA,Wang R,van Wely M,van der Veen F,Mol BWJ,Mochtar MH

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Monoamines play important roles in decidualization, implantation, immune modulation and inflammation. Furthermore, monoamines are potent vasoactive mediators that regulate blood flow and capillary permeability. Regulation of the uterine blood flow is important both during menstruation and pregnancy. Adequate...

journal_title：Human reproduction update

authors： Hansson SR,Bottalico B,Noskova V,Casslén B

更新日期：2009-03-01 00:00:00