Efficient expression of foreign proteins in roots from tobravirus vectors.

abstract：:We have previously shown that the late promoter of the human papovavirus BK (prototype) is contained within the three 68-bp repeats and a 66-bp region to the late side of the repeats which together constitute the early promoter enhancer. We have now carried out unidirectional deletion and linker scan analyses of these...

journal_title：Virology

authors： Cassill JA,Deyerle KL,Subramani S

更新日期：1989-03-01 00:00:00

abstract：:The mature flavivirus capsid protein (virion C) is commonly thought to be free in the cytoplasm of infected cells and to form a nucleocapsid-like complex with genomic RNA in mature virus particles. There is little sequence conservation among flavivirus virion C proteins, but they are similar in size (e.g., 99 amino ac...

journal_title：Virology

authors： Markoff L,Falgout B,Chang A

更新日期：1997-06-23 00:00:00

abstract：:Two genetically distinct infectious recombinant virus clones (pMLV, constructed from Ingelvac PRRS MLV and pMN184, constructed from virulent strain MN184) were developed to study attenuation of contemporary porcine reproductive and respiratory syndrome virus (PRRSV) strain MN184. Two reciprocal chimeric clones (pMLVOR...

journal_title：Virology

authors： Wang Y,Liang Y,Han J,Burkhart KM,Vaughn EM,Roof MB,Faaberg KS

更新日期：2008-02-20 00:00:00

abstract：:The genomes of human herpes virus type-1 and type-2 share a high degree of sequence identity; yet, they exhibit important differences in pathology in their natural human host as well as in animal host and cell cultures. Here, we report the comparative analysis of the time and relative abundance profiles of the transcr...

journal_title：Virology

authors： Aguilar JS,Devi-Rao GV,Rice MK,Sunabe J,Ghazal P,Wagner EK

更新日期：2006-04-25 00:00:00

abstract：:Monoclonal antibodies to the matrix or E1 glycoprotein of mouse hepatitis virus (MHV) were tested for their ability to protect mice from a normally lethal challenge of MHV-4. Four antibodies were tested, and two of these, J.1.3 and J.3.9, were protective. Protection did not correlate with virus neutralization in vitro...

journal_title：Virology

authors： Fleming JO,Shubin RA,Sussman MA,Casteel N,Stohlman SA

更新日期：1989-01-01 00:00:00

abstract：:Successful HIV-1 infection requires a number of specific stages leading to integration of the provirus. We previously suggested that members of the VPAC neuroendocrine receptor family may play a role in HIV-1 infection. We now show that stimulation of the VPAC2 receptor with specific agonists provides strong resistanc...

journal_title：Virology

authors： Bokaei PB,Ma XZ,Sakac D,Branch DR

更新日期：2007-05-25 00:00:00

abstract：:Herpes simplex virus encodes proteins, such as DNA polymerase, that are essential for its replication and proteins, such as thymidine kinase, that are not essential for replication in cell culture, but are important for pathogenesis in animal models. However, certain mutations affecting these proteins exert little or ...

journal_title：Virology

authors： Jacobson J,Kramer M,Rozenberg F,Hu A,Coen DM

更新日期：1995-01-10 00:00:00

abstract：:The extent of viral DNA methylation in non-virus-producing benign and malignant tumors induced by the Shope (rabbit) papilloma virus was investigated with the two isoschizomeric restriction endonucleases MspI and HpaII. The overall extent of methylation is variable in papillomas and uniformly higher in carcinomas. In ...

journal_title：Virology

authors： Wettstein FO,Stevens JG

更新日期：1983-04-30 00:00:00

abstract：:Turnip crinkle virus (TCV) is associated with many subviral RNAs including satellite (sat-) RNAs which require a helper virus for infectivity. When plants were inoculated with TCV and transcripts of TCV sat-RNA C containing deletions of 3 to 8 nucleotides beginning at position 100 and extending toward the 5' end, some...

journal_title：Virology

authors： Carpenter CD,Cascone PJ,Simon AE

更新日期：1991-08-01 00:00:00

abstract：:Due to the worldwide prevalence of antibiotic resistant strains, phages therapy has been revitalized recently. In this study, an Enterococcus faecium phage named IME-EFm5 was isolated from hospital sewage. Whole genomic sequence analysis demonstrated that IME-EFm5 belong to the Siphoviridae family, and has a double-st...

journal_title：Virology

authors： Gong P,Cheng M,Li X,Jiang H,Yu C,Kahaer N,Li J,Zhang L,Xia F,Hu L,Sun C,Feng X,Lei L,Han W,Gu J

更新日期：2016-05-01 00:00:00

abstract：:It has previously been shown that the genome of RF virus, a variant of the human papovavirus, BK, consists of two DNA species, one (R1a) with a deletion corresponding to the early and the other (R2) with a deletion corresponding to the late region of BKV (A. Pater, M.M. Pater, and G. di Mayorca (1980). J. Virol. 36, 4...

journal_title：Virology

authors： Pater A,Pater MM,Chang LS,Slawin K,Di Mayorca G

更新日期：1983-12-01 00:00:00

abstract：:Viroids are small, nontranslatable pathogenic RNAs that replicate autonomously and traffic systemically in their host plants. We have used in situ hybridization to analyze the trafficking pattern of Potato spindle tuber viroid (PSTVd) in tomato and Nicotiana benthamiana. When PSTVd was inoculated onto the stem of a pl...

journal_title：Virology

authors： Zhu Y,Green L,Woo YM,Owens R,Ding B

更新日期：2001-01-05 00:00:00

abstract：:Oral transmission of human immunodeficiency virus (HIV) in adult populations is rare. However, HIV spread across fetal/neonatal oropharyngeal epithelia could be important in mother-to-child transmission. Analysis of HIV transmission across polarized adult and fetal oral epithelial cells revealed that HIV transmigrates...

journal_title：Virology

authors： Tugizov SM,Herrera R,Veluppillai P,Greenspan D,Soros V,Greene WC,Levy JA,Palefsky JM

更新日期：2011-01-20 00:00:00

abstract：:In our in vitro model for HPV16-mediated transformation, HPV16-immortalized human keratinocytes (HKc/HPV16) give rise to differentiation resistant, premalignant cells (HKc/DR). HKc/DR, but not HKc/HPV16, are resistant to growth inhibition by transforming growth factor beta (TGF-β), due to a partial loss of TGF-β recep...

journal_title：Virology

authors： Kowli S,Velidandla R,Creek KE,Pirisi L

更新日期：2013-12-01 00:00:00

abstract：:The complete nucleotide sequence of the middle component RNA (M RNA) of the comovirus bean pod mottle virus (BPMV) has been determined. The sequence consists of 3662 nucleotides and contains a single long open reading frame sufficient to code for a protein of 113,353 Da. The proteolytic processing sites within this pr...

journal_title：Virology

authors： MacFarlane SA,Shanks M,Davies JW,Zlotnick A,Lomonossoff GP

更新日期：1991-07-01 00:00:00

abstract：:Genetic variants surrounding the interferon-λ3 (IFNL3) gene are strongly associated with clearance of hepatitis C virus (HCV). A variant (rs368234815 TT/ΔG) upstream of IFNL3 was recently implicated to control expression of a novel gene termed IFNL4. We conducted genetic analysis of rs368234815 in a chronic HCV patien...

journal_title：Virology

authors： Lu YF,Goldstein DB,Urban TJ,Bradrick SS

更新日期：2015-02-01 00:00:00

abstract：:Gammaherpesviruses establish life-long infection in most adults and are associated with the development of B cell lymphomas. While the interaction between gammaherpesviruses and splenic B cells has been explored, very little is known about gammaherpesvirus infection of B-1 B cells, innate-like B cells that primarily r...

journal_title：Virology

authors： Rekow MM,Darrah EJ,Mboko WP,Lange PT,Tarakanova VL

更新日期：2016-05-01 00:00:00

abstract：:Rabbit and human papillomaviruses are strictly epitheliotropic and their DNA replicates extrachromosomally in benign lesions (warts) of their natural host. Their tissue and host specificity is thought to be genetically controlled and may account for the inefficiency in transforming heterologous cells. In our hands, CR...

journal_title：Virology

authors： Nasseri M,Wettstein FO

更新日期：1987-12-01 00:00:00

abstract：:Specific binding sites for Epstein-Barr virus (EBV) nuclear antigen (EBNA-1), isolated and semipurified from EBV-transformed nonproductive Raji cells, were visualized on the molecule of EBV DNA by electron microscopy and mapped. Two measures had to be applied to counteract the limited purity of the EBNA-1 preparation:...

journal_title：Virology

authors： Reischig J,Bartsch D,Polack A,Vonka V,Hirsch I

更新日期：1987-10-01 00:00:00

abstract：:Zika virus (ZIKV) nonstructural protein 5 (NS5) is a multifunctional protein possessing methyltransferase and RNA-dependent RNA polymerase activities. In the present study, we have carried out an extensive mutagenesis analysis to determine the importance of nuclear localization sequences (NLS) of NS5 in its nuclear ac...

journal_title：Virology

authors： Ji W,Luo G

更新日期：2020-02-01 00:00:00

abstract：:Hepatitis B virus transcripts and DNA from paired samples of neoplastic and nonneoplastic liver tissue of HBsAg seropositive patients were analyzed. The data obtained support the view that transcription of integrated DNA is frequent, both in neoplastic as well as in nonneoplastic liver tissue. In the case of one patie...

journal_title：Virology

authors： Loncarević IF,Schranz P,Zentgraf H,Liang XH,Herrmann G,Tang ZY,Schröder CH

更新日期：1990-01-01 00:00:00

abstract：:The sequences of 189 residues from the 3' terminus of three RNAs of one strain and two RNAs of another strain of tomato aspermy virus have been determined; there was almost complete sequence homology between the RNAs. A base-paired transfer RNA-like structure is proposed for tomato aspermy virus RNAs which is similar ...

journal_title：Virology

authors： Wilson PA,Symons RH

更新日期：1981-07-15 00:00:00

abstract：:Extensive cell killing and cytopathology were observed within 24 hr after exposure of a clonal cell line of human T-4 lymphocytes (RH9) to culture supernatants containing human immunodeficiency virus (HIV). Ultraviolet-irradiated HIV-containing culture fluids were also capable of killing RH9 cells and of inducing spec...

journal_title：Virology

authors： Rasheed S,Gottlieb AA,Garry RF

更新日期：1986-10-30 00:00:00

abstract：:Attenuated mutants of Venezuelan equine encephalitis virus (VEE) were isolated by selection for rapid penetration of cultured cells (R. E. Johnston and J. F. Smith, 1988, Virology 162, 437-443). Sequence analysis of these mutants identified candidate attenuating mutations at four loci in the VEE E2 glycoprotein gene: ...

journal_title：Virology

authors： Davis NL,Powell N,Greenwald GF,Willis LV,Johnson BJ,Smith JF,Johnston RE

更新日期：1991-07-01 00:00:00

abstract：:Evidence is presented for the glycosylation of the cauliflower mosaic virus (CaMV) capsid polypeptide. Fluorescent derivatives of concanavalin A (Con A) were shown to bind specifically to the dissociated CaMV capsid polypeptides in polyacrylamide gels. Con A also bound specifically to intact CaMV, so inhibiting the at...

journal_title：Virology

authors： Du Plessis DH,Smith P

更新日期：1981-03-01 00:00:00

abstract：:For successful penetration of HIV-1, the formation of a fusion pore may be required in order to accumulate critical numbers of fusion-activated gp41 with the help of fluidization of the plasma membrane and viral envelope. An increase in temperature to 40 degrees C after viral adsorption at 25 degrees C enhanced the in...

journal_title：Virology

authors： Harada S,Monde K,Tanaka Y,Kimura T,Maeda Y,Yusa K

更新日期：2008-01-05 00:00:00

abstract：:The longest open reading frame of turnip yellow mosaic virus genomic RNA (ORF-206) encodes a 206-kDa nonstructural protein. The most prominent in vitro translation products of ORF-206 are the full-length p206 and a shorter N-coterminal 150-kDa protein. We have confirmed these assignments by immunoprecipitation of in v...

journal_title：Virology

authors： Bransom KL,Weiland JJ,Dreher TW

更新日期：1991-09-01 00:00:00

abstract：:Therapeutic immunization of HIV-1-infected individuals may induce and/or enhance HIV-1-specific immune responses and decrease the dependency on antiretroviral drug treatment. However, repeated immunizations with live-recombinant vectors may induce vector-specific immune responses that interfere with the elicitation of...

journal_title：Virology

authors： Hel Z,Nacsa J,Tsai WP,Thornton A,Giuliani L,Tartaglia J,Franchini G

更新日期：2002-12-05 00:00:00

abstract：:ZEBRA, a transcription factor and DNA replication protein encoded by the Epstein-Barr virus (EBV) BZLF1 gene, plays indispensable roles in the EBV lytic cycle. We recently described the phenotypes of 46 single amino acid substitutions introduced into the DNA-recognition region of ZEBRA [Heston, L., El-Guindy, A., Coun...

journal_title：Virology

authors： Park R,Heston L,Shedd D,Delecluse HJ,Miller G

更新日期：2008-12-20 00:00:00

abstract：:Viruses of the Norovirus genus (Caliciviridae family) are a major cause of human gastroenteritis. In some viruses, recombination is an important evolutionary process and therefore we should try to discover the quantity and characteristics of such events in Noroviruses. In order to identify recombination events, multip...

journal_title：Virology

authors： Etherington GJ,Dicks J,Roberts IN

更新日期：2006-02-05 00:00:00