Estimating the mortality impacts of particulate matter: what can be learned from between-study variability?

abstract：:Asbestos and other mineral fibers are carcinogenic to humans and animals but differ from many carcinogens in that they do not induce gene mutations. An understanding of these interesting human carcinogens, therefore, is an important problem in cancer research. Asbestos and other fibers induce predominantly two types o...

journal_title：Environmental health perspectives

authors： Barrett JC,Lamb PW,Wiseman RW

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND:Tetraethyl lead was phased out of gasoline in Uganda in 2005. Recent mitigation of an important source of lead exposure suggests examination and re-evaluation of the prevalence of childhood lead poisoning in this country. Ongoing concerns persist about exposure from the Kiteezi landfill in Kampala, the count...

journal_title：Environmental health perspectives

authors： Graber LK,Asher D,Anandaraja N,Bopp RF,Merrill K,Cullen MR,Luboga S,Trasande L

更新日期：2010-06-01 00:00:00

abstract：:The effects of global change on biodiversity and ecosystem functioning encompass multiple complex dynamic processes. Climate change and exposure to endocrine-disrupting chemicals (EDCs) are currently regarded as two of the most serious anthropogenic threats to biodiversity and ecosystems. We should, therefore, be espe...

journal_title：Environmental health perspectives

authors： Jenssen BM

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:Exposure to inorganic arsenic is associated with numerous adverse health outcomes, with susceptibility differing by sex. Although evidence from in vitro studies suggests that arsenic alters post-translational histone modifications (PTHMs), evidence in humans is limited. OBJECTIVES:The objectives were to det...

journal_title：Environmental health perspectives

authors： Howe CG,Liu X,Hall MN,Slavkovich V,Ilievski V,Parvez F,Siddique AB,Shahriar H,Uddin MN,Islam T,Graziano JH,Costa M,Gamble MV

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:C60 fullerenes and single-walled carbon nanotubes (SWCNT) are projected to be used in medicine and consumer products with potential human exposure. The hazardous effects of these particles are expected to involve oxidative stress with generation of oxidatively damaged DNA that might be the initiating event i...

journal_title：Environmental health perspectives

authors： Folkmann JK,Risom L,Jacobsen NR,Wallin H,Loft S,Møller P

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Understanding the potential links between extreme weather events and human health in India is important in the context of vulnerability and adaptation to climate change. Research exploring such linkages in India is sparse. OBJECTIVES:We evaluated the association between extreme precipitation and gastrointes...

journal_title：Environmental health perspectives

authors： Bush KF,O'Neill MS,Li S,Mukherjee B,Hu H,Ghosh S,Balakrishnan K

更新日期：2014-03-01 00:00:00

abstract：:Spontaneous fetal death has been observed among various mammalian species after exposure to polychlorinated biphenyls (PCBs). Our exposure-based cohort study assessed the relationship between consumption of PCB-contaminated Lake Ontario sport fish and spontaneous fetal death using 1820 multigravid fertile women from t...

journal_title：Environmental health perspectives

authors： Mendola P,Buck GM,Vena JE,Zielezny M,Sever LE

更新日期：1995-05-01 00:00:00

abstract：:Lead is a male reproductive toxicant. Data suggest that rats dosed with relatively high levels of lead acetate for short periods of time induced changes in the hypothalamic gonadotropin-releasing hormone (GnRH) at the molecular level, but these changes were attenuated with increased concentration of exposure. The curr...

journal_title：Environmental health perspectives

authors： Sokol RZ,Wang S,Wan YJ,Stanczyk FZ,Gentzschein E,Chapin RE

更新日期：2002-09-01 00:00:00

abstract：:Our work has focused on the determination of physiological traits that may facilitate in situ degradation of xenobiotic compounds by indigenous microorganisms. For this our interests center on the following questions: What are the ambient conditions in a benzene, toluene, ethylbenzene, and xylene (BTEX)-contaminated a...

journal_title：Environmental health perspectives

authors： Olsen RH,Mikesell MD,Kukor JJ,Byrne AM

更新日期：1995-06-01 00:00:00

abstract：:The cytotoxic action of a series of mineral dusts has been studied using Chinese hamster V79-4 cells obtained from three separate laboratories in the UK. The dusts which have been studied include samples of asbestos from the Union Internationale Contre le Cancer reference series and an internationally available sample...

journal_title：Environmental health perspectives

authors： Lock SO,Chamberlain M

更新日期：1983-09-01 00:00:00

abstract：:Lung burden analysis was performed on 126 autopsy cases of persons who died in New York City from 1966 through 1968. Of the 126 cases, 107 were probably non-occupationally exposed, judging by occupational history and asbestos body content of lung. Fifty-three of the 107 cases contained short chrysotile fibers/fibrils,...

journal_title：Environmental health perspectives

authors： Langer AM,Nolan RP

更新日期：1994-10-01 00:00:00

abstract：:We have demonstrated that the pyrolysis products of amino acids and proteins in model systems are mutagenic. The mutagenic principles in the pyrolyzates of amino acids have been isolated and identified by Sugimura et al. We have isolated and identified amino-alpha-carbolines from pyrolyzed soybean globulin as mutagens...

journal_title：Environmental health perspectives

authors： Yoshida D,Matsumoto T,Okamoto H,Mizusaki S,Kushi A,Fukuhara Y

更新日期：1986-08-01 00:00:00

abstract：BACKGROUND:Studies on the health effects of polychlorinated biphenyls (PCBs) call for an understanding of past and present human exposure. Time-resolved mechanistic models may supplement information on concentrations in individuals obtained from measurements and/or statistical approaches if they can be shown to reprodu...

journal_title：Environmental health perspectives

authors： Nøst TH,Breivik K,Wania F,Rylander C,Odland JØ,Sandanger TM

更新日期：2016-03-01 00:00:00

abstract：:This report reviews the recent literature on the adverse effects of occupational factors on fertility and related reproductive outcomes. Few studies fulfill the criteria of good study design because of small sample size, insensitive measures of effect, selection, recall, and observation bias, weak if any control of co...

journal_title：Environmental health perspectives

authors： Baranski B

更新日期：1993-07-01 00:00:00

abstract：:Tobacco smoke contains a number of genotoxic compounds that are metabolized to their biologically active forms that subsequently react with cellular DNA to form covalently bound carcinogen-DNA adducts. Several analytical procedures have been developed to detect these adducts in human tissues. Using the nuclease P1-enh...

journal_title：Environmental health perspectives

authors： Hansen C,Asmussen I,Autrup H

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND:Phthalates, known endocrine disruptors, may play a role in breast carcinogenesis. Few studies have examined phthalates in relation to breast cancer (BC), and, to our knowledge, none have considered survival following BC. OBJECTIVES:We examined 11 urinary phthalate metabolites, individually and as molar sum ...

journal_title：Environmental health perspectives

authors： Parada H Jr,Gammon MD,Chen J,Calafat AM,Neugut AI,Santella RM,Wolff MS,Teitelbaum SL

更新日期：2018-04-26 00:00:00

abstract：BACKGROUND:Epidemiological research on effects of transportation noise on incident hypertension is inconsistent. OBJECTIVES:We aimed to investigate whether residential road traffic noise increases the risk for hypertension. METHODS:In a population-based cohort of 57,053 individuals 50-64 years of age at enrollment, w...

journal_title：Environmental health perspectives

authors： Thacher JD,Poulsen AH,Roswall N,Hvidtfeldt U,Raaschou-Nielsen O,Jensen SS,Ketzel M,Brandt J,Overvad K,Tjønneland A,Münzel T,Sørensen M

更新日期：2020-05-01 00:00:00

abstract：:To set occupational exposure limits (OELs) for aerosol particles, dusts, or chemicals, one has to evaluate whether mechanistic considerations permit identification of a no observed effect level (NOEL). In the case of carcinogenic effects, this can be assumed if no genotoxicity is involved, and exposure is considered s...

journal_title：Environmental health perspectives

authors： Greim HA,Ziegler-Skylakakis K

更新日期：1997-09-01 00:00:00

abstract：:Repeated inhalation of silica dust can lead to inflammation and fibrosis in human lung and in experimental animal models. The alveolar macrophage is believed to play a pivotal role in this process. Numerous macrophage-derived growth factors, cytokines, and arachidonic acid metabolites have been shown to contribute to ...

journal_title：Environmental health perspectives

authors： Koren HS,Joyce M,Devlin RB,Becker S,Driscoll K,Madden MC

更新日期：1992-07-01 00:00:00

abstract：:Adults eating a Western diet digest and absorb ingested food containing approximately 100 g fat, 350 g carbohydrate, and 75 g protein daily. Normal fat absorption requires adequate gastric, pancreatic, liver-biliary, mucosal, and lymphatic function. Carbohydrate and protein absorption is much less dependent on liver-b...

journal_title：Environmental health perspectives

authors： Heizer WD

更新日期：1979-12-01 00:00:00

abstract：BACKGROUND:Although previous studies have reported negative associations between exposure to air pollution and cognition, studies of the effects of prenatal and postnatal exposures in early childhood have been limited. OBJECTIVES:We sought to assess the role exposure to fine particulate matter ([Formula: see text]) du...

journal_title：Environmental health perspectives

authors： Rivas I,Basagaña X,Cirach M,López-Vicente M,Suades-González E,Garcia-Esteban R,Álvarez-Pedrerol M,Dadvand P,Sunyer J

更新日期：2019-05-01 00:00:00

abstract：:This paper reports on the prevalence of lead poisoning in children between 1 and 5 years of age living in a marginal area to the north of Mexico City and also includes an evaluation of sources of exposure to this metal in the same area. The results show that 67.5% of the children studied have blood lead (PbB) levels >...

journal_title：Environmental health perspectives

authors： López-Carrillo L,Torres-Sánchez L,Garrido F,Papaqui-Hernández J,Palazuelos-Rendón E,López-Cervantes M

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND:Cockroaches and mice, which are common in urban homes, are sources of allergens capable of triggering asthma symptoms. Traditional pest control involves the use of scheduled applications of pesticides by professionals as well as pesticide use by residents. In contrast, integrated pest management (IPM) involv...

journal_title：Environmental health perspectives

authors： Kass D,McKelvey W,Carlton E,Hernandez M,Chew G,Nagle S,Garfinkel R,Clarke B,Tiven J,Espino C,Evans D

更新日期：2009-08-01 00:00:00

abstract：:The presence of blue-green algae (BGA) toxins in surface waters used for drinking water sources and recreation is receiving increasing attention around the world as a public health concern. However, potential risks from exposure to these toxins in contaminated health food products that contain BGA have been largely ig...

journal_title：Environmental health perspectives

authors： Gilroy DJ,Kauffman KW,Hall RA,Huang X,Chu FS

更新日期：2000-05-01 00:00:00

abstract：:Pesticides used in agriculture may cause adverse health effects among the population living near agricultural areas. However, identifying the populations most likely to be exposed is difficult. We conducted a feasibility study to determine whether satellite imagery could be used to reconstruct historical crop patterns...

journal_title：Environmental health perspectives

authors： Ward MH,Nuckols JR,Weigel SJ,Maxwell SK,Cantor KP,Miller RS

更新日期：2000-01-01 00:00:00

abstract：:Organochlorines are persistent lipophilic compounds that accumulate in Inuit people living in circumpolar countries. Organochlorines accumulate as a result of the Inuits' large consumption of sea mammal fat; however, available data are limited to blood lipids, milk fat, and adipose tissue. We report results of organoc...

journal_title：Environmental health perspectives

authors： Dewailly E,Mulvad G,Pedersen HS,Ayotte P,Demers A,Weber JP,Hansen JC

更新日期：1999-10-01 00:00:00

abstract：OBJECTIVE:We previously demonstrated that among 54 infants in neonatal intensive care units, exposure to polyvinyl chloride plastic medical devices containing the plasticizer di(2-ethylhexyl) phthalate (DEHP) is associated with urinary concentrations of mono(2-ethylhexyl) phthalate (MEHP) , a DEHP metabolite. In this f...

journal_title：Environmental health perspectives

authors： Weuve J,Sánchez BN,Calafat AM,Schettler T,Green RA,Hu H,Hauser R

更新日期：2006-09-01 00:00:00

abstract：:Environmental estrogens are of particular concern when exposure occurs during embryonic development. Although there are good models to study estrogenic activity of chemicals in adult animals, developmental exposure is much more difficult to test. The weak estrogenic activity of the environmental estrogen bisphenol A (...

journal_title：Environmental health perspectives

authors： Lemmen JG,Arends RJ,van der Saag PT,van der Burg B

更新日期：2004-11-01 00:00:00

abstract：:There are still many uncertainties regarding the risk of adverse pregnancy outcomes associated with exposure to drinking water disinfection by-products. In Montréal, Québec, Canada, we carried out a hospital-based case-control study including 493 cases of intrauterine growth restriction defined as birth weight below t...

journal_title：Environmental health perspectives

authors： Infante-Rivard C

更新日期：2004-08-01 00:00:00

abstract：:The effects of chrysotile on DNA synthesis in the gastrointestinal tract of the rat were studied by measuring the uptake of tritium-labeled thymidine; whole stomach, small intestine, colon liver were removed, cleaned, and homogenized and the DNA was isolated and assayed for tritium label.A dose-response study indicate...

journal_title：Environmental health perspectives

authors： Amacher DE,Alarif A,Epstein SS

更新日期：1974-12-01 00:00:00