Associations between Blood and Urine Arsenic Concentrations and Global Levels of Post-Translational Histone Modifications in Bangladeshi Men and Women.

abstract：OBJECTIVE:We previously demonstrated that among 54 infants in neonatal intensive care units, exposure to polyvinyl chloride plastic medical devices containing the plasticizer di(2-ethylhexyl) phthalate (DEHP) is associated with urinary concentrations of mono(2-ethylhexyl) phthalate (MEHP) , a DEHP metabolite. In this f...

journal_title：Environmental health perspectives

authors： Weuve J,Sánchez BN,Calafat AM,Schettler T,Green RA,Hu H,Hauser R

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:The World Health Organization (WHO) released the fourth edition of Guidelines for Drinking-Water Quality in July 2011. In this edition, the 400-µg/L drinking-water guideline for manganese (Mn) was discontinued with the assertion that because "this health-based value is well above concentrations of manganese ...

journal_title：Environmental health perspectives

authors： Frisbie SH,Mitchell EJ,Dustin H,Maynard DM,Sarkar B

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Despite experimental evidence, most epidemiologic studies to date have not supported an association between exposure to persistent organic pollutants (POP) and breast cancer incidence in humans. This may be attributable to difficulties in estimating blood/tissue POP concentration at critical time periods of ...

journal_title：Environmental health perspectives

authors： Verner MA,Charbonneau M,López-Carrillo L,Haddad S

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVE:We synthesized the main findings from an international epidemiologic study on the impact of biopersistent organic pollutants (POPs) on human reproductive function. DATA SOURCES AND EXTRACTION:We used a database with interview and biological data from 2,269 women and their spouses, and 18 published core paper...

journal_title：Environmental health perspectives

authors： Bonde JP,Toft G,Rylander L,Rignell-Hydbom A,Giwercman A,Spano M,Manicardi GC,Bizzaro D,Ludwicki JK,Zvyezday V,Bonefeld-Jørgensen EC,Pedersen HS,Jönsson BA,Thulstrup AM,INUENDO.

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Animal studies suggest that early-life lead exposure influences gene expression and production of proteins associated with Alzheimer's disease (AD). OBJECTIVES:We attempted to assess the relationship between early-life lead exposure and potential biomarkers for AD among young men and women. We also attempte...

journal_title：Environmental health perspectives

authors： Mazumdar M,Xia W,Hofmann O,Gregas M,Ho Sui S,Hide W,Yang T,Needleman HL,Bellinger DC

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Human exposure to inorganic arsenic (iAs), a potent oxidative stressor, causes various dermal disorders, including hyperkeratosis and skin cancer. Nuclear factor-erythroid 2-related factor 1 (NRF1, also called NFE2L1) plays a critical role in regulating the expression of many antioxidant response element (AR...

journal_title：Environmental health perspectives

authors： Zhao R,Hou Y,Xue P,Woods CG,Fu J,Feng B,Guan D,Sun G,Chan JY,Waalkes MP,Andersen ME,Pi J

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Endocrine-disrupting chemicals have been shown to have broad effects on development, but their mutagenic actions that can lead to cancer have been less clearly demonstrated. Physiological levels of estrogen have been shown to stimulate DNA damage in breast epithelial cells through mechanisms mediated by estr...

journal_title：Environmental health perspectives

authors： Majhi PD,Sharma A,Roberts AL,Daniele E,Majewski AR,Chuong LM,Black AL,Vandenberg LN,Schneider SS,Dunphy KA,Jerry DJ

更新日期：2020-01-01 00:00:00

abstract：:Acetylcholinesterase (AChE) is the enzyme that hydrolyzes the neurotransmitter acetylcholine at cholinergic synapses and neuromuscular junctions. However, results from our laboratory and others indicate that AChE has an extrasynaptic, noncholinergic role during neural development. This article is a review of our findi...

journal_title：Environmental health perspectives

authors： Bigbee JW,Sharma KV,Gupta JJ,Dupree JL

更新日期：1999-02-01 00:00:00

abstract：:Fish and other seafood may contain organic mercury but also beneficial nutrients such as n-3 polyunsaturated fatty acids. We endeavored to study whether maternal fish consumption during pregnancy harms or benefits fetal brain development. We examined associations of maternal fish intake during pregnancy and maternal h...

journal_title：Environmental health perspectives

authors： Oken E,Wright RO,Kleinman KP,Bellinger D,Amarasiriwardena CJ,Hu H,Rich-Edwards JW,Gillman MW

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Ocean pollution affects marine organisms and ecosystems as well as humans. The International Oceanographic Commission recommends ocean health monitoring programs to investigate the presence of marine contaminants and the health of threatened species and the use of multiple and early-warning biomarker approac...

journal_title：Environmental health perspectives

authors： Godard-Codding CA,Clark R,Fossi MC,Marsili L,Maltese S,West AG,Valenzuela L,Rowntree V,Polyak I,Cannon JC,Pinkerton K,Rubio-Cisneros N,Mesnick SL,Cox SB,Kerr I,Payne R,Stegeman JJ

更新日期：2011-03-01 00:00:00

abstract：:Mass poisonings, called yusho and yu-cheng, occurred in western Japan in 1968 and central Taiwan in 1979, respectively. These occurrences were separately caused by ingestion of rice oils contaminated with polychlorinated biphenyls (PCBs), polychlorinated dibenzofurans (PCDFs) and polychlorinated quaterphenyls. The tot...

journal_title：Environmental health perspectives

authors： Masuda Y

更新日期：1985-05-01 00:00:00

abstract：:Unlike laboratory animals, people are rarely exposed to a single hazardous chemical. However, most of the information documenting adverse human health effects from environmental and occupational contaminants has come from studies focused on exposure to single chemicals, and there is little information available on how...

journal_title：Environmental health perspectives

authors： Carpenter DO,Arcaro KF,Bush B,Niemi WD,Pang S,Vakharia DD

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:Adverse cardiorespiratory health is associated with exposure to ambient particulate matter (PM). The highest PM concentrations in London occur in proximity to waste transfer stations (WTS), sites that experience high numbers of dust-laden, heavy-duty diesel vehicles transporting industrial and household wast...

journal_title：Environmental health perspectives

authors： Godri KJ,Duggan ST,Fuller GW,Baker T,Green D,Kelly FJ,Mudway IS

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Exposure to air pollution has been associated with higher C-reactive protein (CRP) levels, suggesting an inflammatory response. Not much is known about this association in pregnancy. OBJECTIVES:We investigated the associations of air pollution exposure during pregnancy with maternal and fetal CRP levels in ...

journal_title：Environmental health perspectives

authors： van den Hooven EH,de Kluizenaar Y,Pierik FH,Hofman A,van Ratingen SW,Zandveld PY,Lindemans J,Russcher H,Steegers EA,Miedema HM,Jaddoe VW

更新日期：2012-05-01 00:00:00

abstract：:We have witnessed a tremendous increase in our knowledge of the molecular and biochemical mechanisms which underly the activities of the nervous system. Such knowledge is essential in order to determine the basic mechanisms involved in neurotoxic events. An overview of how neurotoxins could conceivably interfere with ...

journal_title：Environmental health perspectives

authors： Damstra T

更新日期：1978-10-01 00:00:00

abstract：:The presence of low concentrations of perchlorate in some drinking water sources has led to concern regarding potential effects on the thyroid. In a recently published report, the National Academy of Sciences indicated that the perchlorate dose required to cause hypothyroidism in adults would probably be > 0.40 mg/kg-...

journal_title：Environmental health perspectives

authors： Crump KS,Gibbs JP

更新日期：2005-08-01 00:00:00

abstract：:Interleukin-3 (IL-3) and granulocyte/macrophage-colony-stimulating factor (GM-CSF) are responsible for maintaining survival and stimulating growth of early dormant hematopoietic progenitor cells (HPC). These cytokines exhibit extensive overlap, with GM-CSF supporting growth and differentiation of myeloid HPC. A charac...

journal_title：Environmental health perspectives

authors： Irons RD,Stillman WS

更新日期：1996-12-01 00:00:00

abstract：:The unique nonrespiratory functions of the lungs have become more apparent in recent years. The isolated perfused lung model offers many advantages over other methods for the study of pulmonary metabolism, xenobiotic disposition and the influence of interactions among agents of different physical forms. Detailed descr...

journal_title：Environmental health perspectives

authors： Niemeier RW

更新日期：1984-06-01 00:00:00

abstract：BACKGROUND:The biological mechanisms involved in inflammatory response to air pollution are not clearly understood. OBJECTIVE:In this study we assessed the association of short-term air pollutant exposure with inflammatory markers and lung function. METHODS:We studied a cohort of 158 asthmatic and 50 nonasthmatic sch...

journal_title：Environmental health perspectives

authors： Barraza-Villarreal A,Sunyer J,Hernandez-Cadena L,Escamilla-Nuñez MC,Sienra-Monge JJ,Ramírez-Aguilar M,Cortez-Lugo M,Holguin F,Diaz-Sánchez D,Olin AC,Romieu I

更新日期：2008-06-01 00:00:00

abstract：:The metabolism of polybrominated biphenyls (PBBs) was studied in vitro by using rat liver microsomes in the presence of NADPH and atmospheric O2. Quantitative recoveries of all PBBs were obtained after incubations with control or 3-methylcholanthrene (MC) induced microsomes. Of the twelve major components, losses of o...

journal_title：Environmental health perspectives

authors： Dannan GA,Moore RW,Aust SD

更新日期：1978-04-01 00:00:00

abstract：:Pregnant rats were exposed by inhalation to vapor concentrations of 100, 200, 400 or 800 ppm of ethylene glycol monopropyl ether acetate on days 6 through 15 of gestation. Concentrations of 400 and 800 ppm reduced the feed intake, mean body weight and red blood cell counts. Mean corpuscular volume and mean corpuscular...

journal_title：Environmental health perspectives

authors： Krasavage WJ,Katz GV

更新日期：1984-08-01 00:00:00

abstract：:Serious problems emerge when evaluating evidence on lead neurotoxicity in children. The extent of these problems and ways to control them were explored in a study of 1291 children from the first class in the schools of Aarhus municipality, Denmark. The lead retention in circumpulpal dentin in shed deciduous teeth was ...

journal_title：Environmental health perspectives

authors： Grandjean P,Lyngbye T,Hansen ON

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:Organophosphates elicit developmental neurotoxicity through multiple mechanisms other than their shared property as cholinesterase inhibitors. Accordingly, these agents may differ in their effects on specific brain circuits. OBJECTIVES:We gave parathion to neonatal rats [postnatal days (PNDs) 1-4], at daily...

journal_title：Environmental health perspectives

authors： Slotkin TA,Bodwell BE,Ryde IT,Levin ED,Seidler FJ

更新日期：2008-10-01 00:00:00

abstract：:Factors affecting the design of an epidemiologic study assessing possible health effects from chemical waste disposal sites are reviewed. Such epidemiologic studies will most likely be prompted either by a known release of chemicals into the environment around the site, or by an unusual disease cluster in a population...

journal_title：Environmental health perspectives

authors： Buffler PA,Crane M,Key MM

更新日期：1985-10-01 00:00:00

abstract：:In this article we report a simple and efficient method for detecting nonsteroidal estrogens in a biologic sample. This method uses polyclonal antibodies to estradiol (E2) to immunoprecipitate these major biologically active steroidal estrogens, leaving behind the nonsteroidal estrogens, which are then detected in a c...

journal_title：Environmental health perspectives

authors： Natarajan K,Overstreet JW,Rogers JM,Denison MS,Chen J,Lohstroh PN,McConnell DS,Lasley BL

更新日期：2002-08-01 00:00:00

abstract：:Exposure of rats to quartz (or various other particles) can lead to the development of lung tumors. At the moment, the mechanisms involved in particle-induced tumor formation are not clarified. However, it is suggested that inflammation, in conjunction with the production of reactive oxygen species (ROS) and an enhanc...

journal_title：Environmental health perspectives

authors： Nehls P,Seiler F,Rehn B,Greferath R,Bruch J

更新日期：1997-09-01 00:00:00

abstract：:Previous investigations suggest that dietary sources of polycyclic aromatic hydrocarbons (PAHs) contribute to the PAH-DNA adduct load in peripheral white blood cells (WBCs). In the current study, we measured PAH-DNA adducts by enzyme-linked immunosorbent assay in WBCs obtained from 47 California wildland (forest) fire...

journal_title：Environmental health perspectives

authors： Rothman N,Poirier MC,Haas RA,Correa-Villasenor A,Ford P,Hansen JA,O'Toole T,Strickland PT

更新日期：1993-03-01 00:00:00

abstract：:The hypothesis has been put forward that humans and wildlife species adverse suffered adverse health effects after exposure to endocrine-disrupting chemicals. Reported adverse effects include declines in populations, increases in cancers, and reduced reproductive function. The U.S. Environmental Protection Agency spon...

journal_title：Environmental health perspectives

authors： Kavlock RJ,Daston GP,DeRosa C,Fenner-Crisp P,Gray LE,Kaattari S,Lucier G,Luster M,Mac MJ,Maczka C,Miller R,Moore J,Rolland R,Scott G,Sheehan DM,Sinks T,Tilson HA

更新日期：1996-08-01 00:00:00

abstract：:The association between ambient air pollution and adverse health effects, such as emergency room visits, hospitalizations, and mortality from respiratory and cardiovascular diseases, has been studied extensively in many countries, including Canada. Recently, studies conducted in China, the Czech Republic, and the Unit...

journal_title：Environmental health perspectives

authors： Liu S,Krewski D,Shi Y,Chen Y,Burnett RT

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Incorporating the influence of genetic variation in the risk assessment process is often considered, but no generalized approach exists. Many common human diseases such as asthma, cancer, and cardiovascular disease are complex in nature, as they are influenced variably by environmental, physiologic, and gene...

journal_title：Environmental health perspectives

authors： Demchuk E,Yucesoy B,Johnson VJ,Andrew M,Weston A,Germolec DR,De Rosa CT,Luster MI

更新日期：2007-02-01 00:00:00