Cytotoxic action of mineral dusts on CHV 79 cells in vitro: factors affecting toxicity.

abstract：BACKGROUND:Psychological sequelae are among the most pronounced effects in populations following exposure to oil spills. Women in particular represent a vulnerable yet influential population but have remained relatively understudied with respect to the Deepwater Horizon oil spill (DHOS). OBJECTIVE:To describe the rela...

journal_title：Environmental health perspectives

authors： Rung AL,Gaston S,Oral E,Robinson WT,Fontham E,Harrington DJ,Trapido E,Peters ES

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Methylmercury (MeHg) exposure has been linked to an increased risk of coronary heart disease (CHD). Paraoxonase 1 (PON1), an enzyme located in the high-density-lipoprotein (HDL) fraction of blood lipids, may protect against CHD by metabolizing toxic oxidized lipids associated with low-density liproprotein an...

journal_title：Environmental health perspectives

authors： Ayotte P,Carrier A,Ouellet N,Boiteau V,Abdous B,Sidi EA,Château-Degat ML,Dewailly É

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:The 1974 Safe Drinking Water Act (SDWA) regulates >170,000 public water systems to protect health, but not >13 million private wells. State and local government requirements for private well water testing are rare and inconsistent; the responsibility to ensure water safety remains with individual households....

journal_title：Environmental health perspectives

authors： Zheng Y,Flanagan SV

更新日期：2017-08-03 00:00:00

abstract：:The extracellular lining of the lungs is reviewed. The pulmonary extracellular lining is a complex mixture of phospholipids, proteins and carbohydrates which is absolutely essential for the maintenance of normal pulmonary functions such as gas exchange. Without the lining the lungs would collapse. Alterations in the p...

journal_title：Environmental health perspectives

authors： George G,Hook GE

更新日期：1984-04-01 00:00:00

abstract：BACKGROUND:Adapting to extreme heat is becoming more critical as our climate changes. Previous research reveals that very few communities in the United States have programs to sufficiently prevent health problems during hot weather. OBJECTIVE:Our goal was to examine county-level local heat preparedness and response in...

journal_title：Environmental health perspectives

authors： White-Newsome JL,Ekwurzel B,Baer-Schultz M,Ebi KL,O'Neill MS,Anderson GB

更新日期：2014-06-01 00:00:00

abstract：:The neurochemical basis of memory has been approached experimentally in four different ways: the bioassay; the interventive approach; the interventive-correlative approach; and the correlative approach. These approaches are fundamentally similar to those used for the study of the chemistry of any behavior. Each of the...

journal_title：Environmental health perspectives

authors： Dunn AJ

更新日期：1978-10-01 00:00:00

abstract：:Ecological risk assessment can be enhanced with predictive models for metal toxicity. Modelings of published data were done under the simplifying assumption that intermetal trends in toxicity reflect relative metal-ligand complex stabilities. This idea has been invoked successfully since 1904 but has yet to be applied...

journal_title：Environmental health perspectives

authors： Newman MC,McCloskey JT,Tatara CP

更新日期：1998-12-01 00:00:00

abstract：:Exposure of rats to quartz (or various other particles) can lead to the development of lung tumors. At the moment, the mechanisms involved in particle-induced tumor formation are not clarified. However, it is suggested that inflammation, in conjunction with the production of reactive oxygen species (ROS) and an enhanc...

journal_title：Environmental health perspectives

authors： Nehls P,Seiler F,Rehn B,Greferath R,Bruch J

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:Drinking water in multiple water districts in the Mid-Ohio Valley has been contaminated with perfluorooctanoic acid (PFOA), which was released by a nearby DuPont chemical plant. Two highly contaminated water districts began granular activated carbon filtration in 2007. OBJECTIVES:To determine the rate of de...

journal_title：Environmental health perspectives

authors： Bartell SM,Calafat AM,Lyu C,Kato K,Ryan PB,Steenland K

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Exposure to flame retardants has been associated with negative health outcomes including metabolic effects. As polybrominated diphenyl ether flame retardants were pulled from commerce, human exposure to new flame retardants such as Firemaster® 550 (FM550) has increased. Although previous studies in murine sy...

journal_title：Environmental health perspectives

authors： Tung EWY,Peshdary V,Gagné R,Rowan-Carroll A,Yauk CL,Boudreau A,Atlas E

更新日期：2017-09-14 00:00:00

abstract：:We assessed chlorinated hydrocarbon contamination of mink and river otters on the Columbia and Fraser River systems of northwestern North America, in relation to morphological measures of condition. We obtained carcasses of mink and river otters from commercial trappers during the winters 1994-1995 and 1995-1996. Necr...

journal_title：Environmental health perspectives

authors： Harding LE,Harris ML,Stephen CR,Elliott JE

更新日期：1999-02-01 00:00:00

abstract：:The 11 September 2001 terrorist attack on New York City's World Trade Center (WTC) caused an unprecedented environmental emergency. The collapse of the towers sent a tremendous cloud of crushed building materials and other pollutants into the air of lower Manhattan. In response to the calamity, federal, state, and cit...

journal_title：Environmental health perspectives

authors： Gavett SH

更新日期：2003-06-01 00:00:00

abstract：:This study assessed whether exposure of male rats to two estrogenic, environmental chemicals, 4-octylphenol (OP) and butyl benzyl phthalate (BBP) during gestation or during the first 21 days of postnatal life, affected testicular size or spermatogenesis in adulthood (90-95 days of age). Chemicals were administered via...

journal_title：Environmental health perspectives

authors： Sharpe RM,Fisher JS,Millar MM,Jobling S,Sumpter JP

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND:Human epidemiological and animal studies suggest that developmental exposure to contaminants that activate the aryl hydrocarbon receptor (AHR) lead to suppression of immune system function throughout life. The persistence of immune deficiency throughout life suggests that the cellular target of AHR activatio...

journal_title：Environmental health perspectives

authors： Laiosa MD,Tate ER,Ahrenhoerster LS,Chen Y,Wang D

更新日期：2016-07-01 00:00:00

abstract：:As part of a cohort study of the effects of chronic exposure to lead on pregnancy outcome and child development, lead concentrations in the umbilical cord and placental tissues (body and membranes) from 9 late fetal deaths, 23 preterm births, and 18 births associated with premature rupture of the amniotic membranes we...

journal_title：Environmental health perspectives

authors： Baghurst PA,Robertson EF,Oldfield RK,King BM,McMichael AJ,Vimpani GV,Wigg NR

更新日期：1991-01-01 00:00:00

abstract：:Gene expression is a unique way of characterizing how cells and organisms adapt to changes in the external environment. The measurements of gene expression levels upon exposure to a chemical can be used both to provide information about the mechanism of action of the toxicant and to form a sort of "genetic signature" ...

journal_title：Environmental health perspectives

authors： Lettieri T

更新日期：2006-01-01 00:00:00

abstract：:We estimated the disease burden from water, sanitation, and hygiene at the global level taking into account various disease outcomes, principally diarrheal diseases. The disability-adjusted life year (DALY) combines the burden from death and disability in a single index and permits the comparison of the burden from wa...

journal_title：Environmental health perspectives

authors： Prüss A,Kay D,Fewtrell L,Bartram J

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Eliminating silicosis is a priority of the International Labour Organization and the World Health Organization. Prevalence is particularly high in developing countries. OBJECTIVES:We describe trends in silicosis among South African gold miners who had had an autopsy between 1975 and 2007 and quantify the co...

journal_title：Environmental health perspectives

authors： Nelson G,Girdler-Brown B,Ndlovu N,Murray J

更新日期：2010-03-01 00:00:00

abstract：:The metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), the most abundant compound of the aminoimidazoazaarens (AIA) group of mutagens/carcinogens isolated from the crust of fried and broiled meat, was examined in freshly isolated hepatocytes from untreated rat, mouse, hamster, and guinea pig. Activa...

journal_title：Environmental health perspectives

authors： Alexander J,Fossum BH,Holme JA

更新日期：1994-10-01 00:00:00

abstract：:Large quantities of food processing, crop, forestry, and animal solid wastes are generated in the United States each year. The major components of these wastes are biodegradable. However, they also contain components such as nitrogen, human and animal pathogens, medicinals, feed additives, salts, and certain metals, t...

journal_title：Environmental health perspectives

authors： Loehr RC

更新日期：1978-12-01 00:00:00

abstract：:Some of the statistical properties of a simple two-stage model of carcinogenesis are explored. The implications of additive treatment effects versus independent treatment effects on the shape of the dose-response curve are considered. Response that is low-dose linear results in the cases where the mutation rates are a...

journal_title：Environmental health perspectives

authors： Portier CJ

更新日期：1987-12-01 00:00:00

abstract：:Tobacco smoke contains a number of genotoxic compounds that are metabolized to their biologically active forms that subsequently react with cellular DNA to form covalently bound carcinogen-DNA adducts. Several analytical procedures have been developed to detect these adducts in human tissues. Using the nuclease P1-enh...

journal_title：Environmental health perspectives

authors： Hansen C,Asmussen I,Autrup H

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND:"Airwave" is the new communication system currently being rolled out across the United Kingdom for the police and emergency services, based on the Terrestrial Trunked Radio Telecommunications System (TETRA). Some police officers have complained about skin rashes, nausea, headaches, and depression as a conseq...

journal_title：Environmental health perspectives

authors： Wallace D,Eltiti S,Ridgewell A,Garner K,Russo R,Sepulveda F,Walker S,Quinlan T,Dudley S,Maung S,Deeble R,Fox E

更新日期：2010-06-01 00:00:00

abstract：:The possible risk for human health arising from consumption of lead-polluted shellfish was suggested by experiments on the bioavailability for mice of a "biologically detoxified" form of the metal. In this work, young mice were fed with a mixed diet including mussels collected in a Pb-polluted area. Metal concentratio...

journal_title：Environmental health perspectives

authors： Regoli F,Orlando E

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:Recent findings suggest that maternal smoking during pregnancy may play a role in the development of metabolic alterations in offspring during childhood. However, whether such exposure increases the risk of developing similar metabolic alterations during adulthood is uncertain. OBJECTIVE:We evaluated the as...

journal_title：Environmental health perspectives

authors： Cupul-Uicab LA,Skjaerven R,Haug K,Travlos GS,Wilson RE,Eggesbø M,Hoppin JA,Whitworth KW,Longnecker MP

更新日期：2012-11-01 00:00:00

abstract：:In this study, we determined the biologic activity of dichloromethane-extracted particulate matter < 10 micro m in aerodynamic diameter (PM10) obtained from filters at three sites in the Paso del Norte airshed, which includes El Paso, Texas, USA; Juarez, Chihuahua, Mexico, and Sunland Park, New Mexico, USA. The extrac...

journal_title：Environmental health perspectives

authors： Arrieta DE,Ontiveros CC,Li WW,Garcia JH,Denison MS,McDonald JD,Burchiel SW,Washburn BS

更新日期：2003-08-01 00:00:00

abstract：:Naturally occurring radon is a relatively ubiquitous environmental carcinogen to which large numbers of people can be exposed over their lifetimes. The accumulation of radon in homes, therefore, has led to a large program to determine the effects of the densely ionizing alpha particles that are produced when radon dec...

journal_title：Environmental health perspectives

authors： Wolff S,Afzal V,Jostes RF,Wiencke JK

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND:Exposure to organophosphate (OP) pesticides is an occupational hazard for farmworkers and affects their children through the take-home pathway. OBJECTIVES:We examined the effectiveness of a randomized community intervention to reduce pesticide exposure among farmworkers and their children. METHODS:We condu...

journal_title：Environmental health perspectives

authors： Thompson B,Coronado GD,Vigoren EM,Griffith WC,Fenske RA,Kissel JC,Shirai JH,Faustman EM

更新日期：2008-05-01 00:00:00

abstract：:The objective of this study was to provide a basis for effectively protecting nonsmokers from acute sensory impacts and for preventing deterioration of indoor air quality caused by environmental tobacco smoke (ETS) emissions. With an olfactory experiment we determined odor detection thresholds (OT) of sidestream ETS (...

journal_title：Environmental health perspectives

authors： Junker MH,Danuser B,Monn C,Koller T

更新日期：2001-10-01 00:00:00

abstract：:Hamsters were exposed to an aerosol of fused aluminosilicate particles (FAP) labeled with 57Co. Three groups of animals were given bronchopulmonary lavage, beginning at either 1 week, 1 month, or 6 months after exposure. Each treated group was lavaged eight times over a period of 25 days. Each lavage involved 10 salin...

journal_title：Environmental health perspectives

authors： Ellender M,Hodgson A,Wood KL,Moody JC

更新日期：1992-07-01 00:00:00