Estimating the burden of disease from water, sanitation, and hygiene at a global level.

abstract：:This paper examines behavioral changes in natural populations of wildlife associated with pollution. Although some changes such as lack of nest attentiveness and decreased nest defense have been noted, the results have not been consistent and have been difficult to relate to specific pollutants. Experimental studies i...

journal_title：Environmental health perspectives

authors： Peakall DB

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:The incidence of asbestos-induced human cancers is increasing worldwide, and considerable evidence suggests that reactive oxygen species (ROS) are important mediators of these diseases. Our previous studies suggested that mitochondria might be involved in the initiation of oxidative stress in asbestos-expose...

journal_title：Environmental health perspectives

authors： Huang SX,Partridge MA,Ghandhi SA,Davidson MM,Amundson SA,Hei TK

更新日期：2012-06-01 00:00:00

abstract：:Multiple chemical sensitivity (MCS) is a condition in which persons experience negative health effects in multiple organ systems from exposure to low levels of common chemicals. Although symptoms experienced from particular chemicals vary across persons, they are generally stable within persons. The sensitivities ofte...

journal_title：Environmental health perspectives

authors： Gibson PR,Elms AN,Ruding LA

更新日期：2003-09-01 00:00:00

abstract：:Carcinogenic nickel compounds are usually found to be weak mutagens; therefore these compounds may not exert their carcinogenic activity through conventional genotoxic mechanisms. On the other hand, the activities of many nickel compounds have not been adequately investigated. We evaluated the genotoxic activities of ...

journal_title：Environmental health perspectives

authors： Au WW,Heo MY,Chiewchanwit T

更新日期：1994-11-01 00:00:00

abstract：:Polychlorinated biphenyls (PCBs) and dioxins are known as neurotoxic compounds that may modulate sex steroid hormones. Steroid hormones play a mediating role in brain development and may influence behaviors that show sex differences, such as childhood play behavior. In this study we evaluated the effects of perinatal ...

journal_title：Environmental health perspectives

authors： Vreugdenhil HJ,Slijper FM,Mulder PG,Weisglas-Kuperus N

更新日期：2002-10-01 00:00:00

abstract：:A physiologically based pharmacokinetic model for trichloroethylene (TCE) in rodents and humans was calibrated with published toxicokinetic data sets. A Bayesian statistical framework was used to combine previous information about the model parameters with the data likelihood, to yield posterior parameter distribution...

journal_title：Environmental health perspectives

authors： Bois FY

更新日期：2000-05-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to assess whether the joint effects of three androgen receptor antagonists (vinclozolin, flutamide, procymidone) on male sexual differentiation after in utero and postnatal exposures can be predicted based on dose-response data of the individual chemicals. METHODS:Test chemicals and...

journal_title：Environmental health perspectives

authors： Hass U,Scholze M,Christiansen S,Dalgaard M,Vinggaard AM,Axelstad M,Metzdorff SB,Kortenkamp A

更新日期：2007-12-01 00:00:00

abstract：:Polychlorinated biphenyls (PCBs) are a family of persistent organic contaminants suspected to cause adverse effects in wildlife and humans. In rodents, PCBs bind to the aryl hydrocarbon (AhR) and pregnane X receptors (PXR) inducing the expression of catabolic cytochrome p450 enzymes of the CYP1A and 3A families. We fo...

journal_title：Environmental health perspectives

authors： Tabb MM,Kholodovych V,Grün F,Zhou C,Welsh WJ,Blumberg B

更新日期：2004-02-01 00:00:00

abstract：:Isoflavonoids and related compounds such as coumestrol have classically been categorized as phytoestrogens because these environmentally derived substances bind to the estrogen receptor (ER) and increase uterine wet weight in immature rats and mice. Assessment of the binding affinities of isoflavonoids for ER and subs...

journal_title：Environmental health perspectives

authors： Markaverich BM,Webb B,Densmore CL,Gregory RR

更新日期：1995-06-01 00:00:00

abstract：:Most contemporary bioinsecticides are derived from scaled-up cultures of Bacillus thuringiensis subspecies israelensis (Bti) and kurstaki (Btk), whose particulate fractions contain mostly B. thuringiensis spores (> 10(12)/L) and proteinaceous aggregates, including crystal-like parasporal inclusion bodies (PIB). Based ...

journal_title：Environmental health perspectives

authors： Tayabali AF,Seligy VL

更新日期：2000-10-01 00:00:00

abstract：:We examined the estrogenicity of binary mixtures of the hydroxylated polychlorinated biphenyls (OHPCBs) 2,4,6-trichloro-4'-biphenylol (2,4,6-TCB-4'-OH) and 2,3,4,5-tetrachloro-4'-biphenylol and the pesticides endosulfan and dieldrin. The OHPCBs and pesticides were tested in both the MCF-7 focus assay and a competitive...

journal_title：Environmental health perspectives

authors： Arcaro KF,Vakharia DD,Yang Y,Gierthy JF

更新日期：1998-08-01 00:00:00

abstract：:Preterm delivery can lead to serious infant health outcomes, including death and lifelong disability. Small increases in preterm delivery risk in relation to spatial gradients of air pollution have been reported, but previous studies may have controlled inadequately for individual factors. Using a time-series analysis...

journal_title：Environmental health perspectives

authors： Sagiv SK,Mendola P,Loomis D,Herring AH,Neas LM,Savitz DA,Poole C

更新日期：2005-05-01 00:00:00

abstract：:Environmental estrogens are of particular concern when exposure occurs during embryonic development. Although there are good models to study estrogenic activity of chemicals in adult animals, developmental exposure is much more difficult to test. The weak estrogenic activity of the environmental estrogen bisphenol A (...

journal_title：Environmental health perspectives

authors： Lemmen JG,Arends RJ,van der Saag PT,van der Burg B

更新日期：2004-11-01 00:00:00

abstract：:Nicotine and cigarette smoke extract show acute physiological effects: increasing tracheal pressure (PTR), pulmonary artery pressure (PPA), systemic blood pressure (PSYST), and left atrium pressure (PLA); and decreasing cardiac output (QAORTA) and blood flow to the left lower lobe (QLLL). In addition, cigarette smokin...

journal_title：Environmental health perspectives

authors： Kitamura S

更新日期：1987-06-01 00:00:00

abstract：:A brief history of the development of the field of aquatic toxicology is provided. In order to provide a perspective on the state-of-the-art in aquatic toxicology relative to classical toxicology, the two fields are compared from the standpoint of the type of scientist practicing each field, the respective objectives ...

journal_title：Environmental health perspectives

authors： Macek KJ

更新日期：1980-02-01 00:00:00

abstract：:Serious problems emerge when evaluating evidence on lead neurotoxicity in children. The extent of these problems and ways to control them were explored in a study of 1291 children from the first class in the schools of Aarhus municipality, Denmark. The lead retention in circumpulpal dentin in shed deciduous teeth was ...

journal_title：Environmental health perspectives

authors： Grandjean P,Lyngbye T,Hansen ON

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:Traffic noise has been associated with cardiovascular and metabolic disorders. Potential modes of action are through stress and sleep disturbance, which may lead to endocrine dysregulation and overweight. OBJECTIVES:We aimed to investigate the relationship between residential traffic and railway noise and a...

journal_title：Environmental health perspectives

authors： Christensen JS,Raaschou-Nielsen O,Tjønneland A,Overvad K,Nordsborg RB,Ketzel M,Sørensen TIa,Sørensen M

更新日期：2016-03-01 00:00:00

abstract：:In this study, we explored the efficacy of upper-room ultraviolet germicidal irradiation (UVGI) in reducing the concentration of Serratia marcescens and Mycobacterium bovis bacille Calmette-Guérin (BCG) aerosols in enclosed places. We constructed a facility (4.5 m x 3 m x 2.9 m) in which both ceiling- and wall-mounted...

journal_title：Environmental health perspectives

authors： Ko G,First MW,Burge HA

更新日期：2002-01-01 00:00:00

abstract：:This review presents a brief overview of the health effects and exposures of two criteria pollutants--ozone and particulate matter--and two toxic air pollutants--benzene and formaldehyde. These pollutants were selected from the six criteria pollutants and from the 189 toxic air pollutants on the basis of their prevale...

journal_title：Environmental health perspectives

authors： Suh HH,Bahadori T,Vallarino J,Spengler JD

更新日期：2000-08-01 00:00:00

abstract：:Soil samples were collected from 28 fields which had received manure from Michigan's most highly contaminated dairy herds. The number of fields in each concentration range of PBB in soil were: 2, not detectable; 15, 0.0 to 8.0 ppb; 6, 14-102 ppb, and 5, 153 to 371 ppb. Plant tissue sampled from the 10 most highly cont...

journal_title：Environmental health perspectives

authors： Jacobs LW,Chou SF,Tiedje JM

更新日期：1978-04-01 00:00:00

abstract：:Mineral fibers and particulates represent one of the best documented, economically important, and ubiquitously occurring categories of human carcinogens. Yet, while a wealth of information exists concerning the mechanism of action of physical, chemical, and viral carcinogens, virtually nothing is known relative to the...

journal_title：Environmental health perspectives

authors： Hart RW,Daniel FB,Kindig OR,Beach CA,Joseph LB,Wells RC

更新日期：1980-02-01 00:00:00

abstract：:Comments on "Determination of bisphenol A and related aromatic compounds released from Bis-GMA-based composites and sealants by high performance liquid chromatography." by ulgar R, Olea-Serrano MF, Novillo-Fertrell A, Rivas A, Pazos P, Pedraza V, Navajas J-M, Olea N. Environ Health Perspect 108:21-27 (2000). ...

journal_title：Environmental health perspectives

authors： Olea N

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:The widespread use of organophosphorus (OP) pesticides has led to frequent exposure in adults and children. Because such exposure may cause adverse health effects, particularly in children, the sources and patterns of exposure need to be studied further. OBJECTIVES:We assessed young urban/suburban children'...

journal_title：Environmental health perspectives

authors： Lu C,Barr DB,Pearson MA,Waller LA

更新日期：2008-04-01 00:00:00

abstract：:The study reported here presents the results of an investigation of a marsh-cove ecosystem heavily contaminated by cadmium. The most contaminated aquatic sediments were dredged in 1972-73, but the resuspension of the sediments and recycle of water from the dredge spoil resulted in reestablishment of a large contaminat...

journal_title：Environmental health perspectives

authors： Kneip TJ,Hazen RE

更新日期：1979-02-01 00:00:00

abstract：BACKGROUND:Evidence on the association between colorectal cancer and exposure to disinfection by-products in drinking water is inconsistent. OBJECTIVES:We assessed long-term exposure to trihalomethanes (THMs), the most prevalent group of chlorination by-products, to evaluate the association with colorectal cancer. ME...

journal_title：Environmental health perspectives

authors： Villanueva CM,Gracia-Lavedan E,Bosetti C,Righi E,Molina AJ,Martín V,Boldo E,Aragonés N,Perez-Gomez B,Pollan M,Acebo IG,Altzibar JM,Zabala AJ,Ardanaz E,Peiró R,Tardón A,Chirlaque MD,Tavani A,Polesel J,Serraino D,Pi

更新日期：2017-01-01 00:00:00

abstract：:The metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), the most abundant compound of the aminoimidazoazaarens (AIA) group of mutagens/carcinogens isolated from the crust of fried and broiled meat, was examined in freshly isolated hepatocytes from untreated rat, mouse, hamster, and guinea pig. Activa...

journal_title：Environmental health perspectives

authors： Alexander J,Fossum BH,Holme JA

更新日期：1994-10-01 00:00:00

abstract：:Thirty compounds of various chemical classes were investigated for mutagenicity in a collaborative study (three laboratories) using Salmonella typhimurium TA102. With five compounds, hydrazine sulfate, phenylhydrazine, hydralazine, glutardialdehyde, and glyoxal, mutagenicity was detected by all laboratories. Formaldeh...

journal_title：Environmental health perspectives

authors： Müller W,Engelhart G,Herbold B,Jäckh R,Jung R

更新日期：1993-10-01 00:00:00

abstract：:Lead is a male reproductive toxicant. Data suggest that rats dosed with relatively high levels of lead acetate for short periods of time induced changes in the hypothalamic gonadotropin-releasing hormone (GnRH) at the molecular level, but these changes were attenuated with increased concentration of exposure. The curr...

journal_title：Environmental health perspectives

authors： Sokol RZ,Wang S,Wan YJ,Stanczyk FZ,Gentzschein E,Chapin RE

更新日期：2002-09-01 00:00:00

abstract：:In recent years, it has become apparent that minerals can trigger alterations in gene expression by initiating signaling events upstream of gene transactivation. These cascades may be initiated at the cell surface after interaction of minerals with the plasma membrane either through receptorlike mechanisms or integrin...

journal_title：Environmental health perspectives

authors： Mossman BT,Faux S,Janssen Y,Jimenez LA,Timblin C,Zanella C,Goldberg J,Walsh E,Barchowsky A,Driscoll K

更新日期：1997-09-01 00:00:00

abstract：:We used an improved method for trapping carbon-centered radicals (.R) from the gas-phase to compare radical suites trapped from various tobacco smoke and model smoke systems. Using a nitroxide trap, 3-amino-2,2,5,5-tetramethyl-1-pyrrolidinyloxy (3AP), on solid support, we trapped radicals directly from the gas phase, ...

journal_title：Environmental health perspectives

authors： Flicker TM,Green SA

更新日期：2001-08-01 00:00:00