Abstract:
:An allele (263bp) of the nonamyloid component of plaques (NACP)-Repl polymorphism has shown association with sporadic PD in a German population. The authors studied this polymorphism in 100 American PD patients and 100 healthy controls. The authors also studied 46 essential tremor (ET) and 55 Huntington's disease (HD) patients. Allele 263bp was significantly higher in PD patients (OR = 3.86) and ET patients (OR = 6.42) but not HD patients, compared with healthy controls. The association of allele 263bp with PD and ET suggests a possible etiologic link between these two conditions.
journal_name
Neurologyjournal_title
Neurologyauthors
Tan EK,Matsuura T,Nagamitsu S,Khajavi M,Jankovic J,Ashizawa Tdoi
10.1212/wnl.54.5.1195subject
Has Abstractpub_date
2000-03-14 00:00:00pages
1195-8issue
5eissn
0028-3878issn
1526-632Xjournal_volume
54pub_type
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